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  1. Article ; Online: Varenicline Use for Cocaine Dependence.

    Gupta, Abhishek

    The primary care companion for CNS disorders

    2023  Volume 25, Issue 3

    MeSH term(s) Humans ; Varenicline/adverse effects ; Cocaine-Related Disorders/drug therapy ; Nicotinic Agonists/adverse effects ; Cocaine
    Chemical Substances Varenicline (W6HS99O8ZO) ; Nicotinic Agonists ; Cocaine (I5Y540LHVR)
    Language English
    Publishing date 2023-05-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7780
    ISSN (online) 2155-7780
    ISSN 2155-7780
    DOI 10.4088/PCC.22l03375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Outcomes of the Tissue-Tuck Surgical Technique for Recurrent Pterygium.

    Singh, Prabhakar / Gupta, Abhishek

    Cornea

    2024  

    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000003499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1790: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Social prescribing in ethnic minority communities.

    Gupta, Abhishek Kumar

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2021  Volume 71, Issue 704, Page(s) 109

    MeSH term(s) Ethnicity ; Humans ; Minority Groups
    Language English
    Publishing date 2021-02-25
    Publishing country England
    Document type Letter
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp21X715037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 576: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 100: Show issues

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  4. Article ; Online: Automatic Segmentation of Organs-at-Risk in Thoracic Computed Tomography Images Using Ensembled U-Net InceptionV3 Model.

    Ashok, Malvika / Gupta, Abhishek

    Journal of computational biology : a journal of computational molecular cell biology

    2023  Volume 30, Issue 3, Page(s) 346–362

    Abstract: The objective of this article is to automatically segment organs at risk (OARs) for thoracic radiology in computed tomography (CT) scan images. The OARs in the thoracic anatomical region during the radiotherapy treatment are mainly the neighbouring ... ...

    Abstract The objective of this article is to automatically segment organs at risk (OARs) for thoracic radiology in computed tomography (CT) scan images. The OARs in the thoracic anatomical region during the radiotherapy treatment are mainly the neighbouring organs such as the esophagus, heart, trachea, and aorta. The dataset of 40 patients was used in the proposed work by splitting it into three parts: training, validation, and test sets. The implementation was performed on the Google Colab Pro+ framework with 52 GB of RAM and 265 GB of storage space. An ensemble model was evolved for the automatic segmentation of four OARs in thoracic CT images. U-Net with InceptionV3 as the backbone was used, and different hyperparameters were used during the training of the model. The proposed model achieved precise accuracy for OARs segmentation with an average dice coefficient of 0.9413, Hausdorff value of 0.1838, sensitivity of 0.9783, and specificity of 0.9895 on the Test dataset. An ensembled U-Net InceptionV3 model has been proposed, improving the segmentation results compared with the state-of-the-art techniques such as U-Net, ResNet, Vgg16, etc. The results of the experiments revealed that the proposed model effectively improved the performance of the segmentation of the esophagus, heart, trachea, and aorta.
    MeSH term(s) Humans ; Organs at Risk ; Tomography, X-Ray Computed/methods ; Image Processing, Computer-Assisted/methods
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2030900-4
    ISSN 1557-8666 ; 1066-5277
    ISSN (online) 1557-8666
    ISSN 1066-5277
    DOI 10.1089/cmb.2022.0248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Clinico-Microbiological Correlates of Hospital-Acquired Pneumonia: A Hospital-Based Prospective Cohort Study.

    Avisham / Agrawal, Anurag / Gupta, Abhishek

    Cureus

    2023  Volume 15, Issue 12, Page(s) e50707

    Abstract: Background and objectives: Hospital-acquired pneumonia (HAP) is a life-threatening hospital-acquired infection contributing to poor outcomes and mortality. Though the prevalence is comparable, the burden of comorbidities and malnutrition further worsens ...

    Abstract Background and objectives: Hospital-acquired pneumonia (HAP) is a life-threatening hospital-acquired infection contributing to poor outcomes and mortality. Though the prevalence is comparable, the burden of comorbidities and malnutrition further worsens the scenario in developing countries. Infective agents responsible for these infections vary between regions due to the variables involved. There is a dearth of data on clinico-microbiological correlates of HAP from Northern India. With this study, we aim to explore the same and add more evidence to fill the gap.
    Methodology: A hospital-based cohort study was done on ICU patients of the tertiary care center in Northern India including the cohort of patients obeying a strict inclusion criterion. The clinical and microbiological correlates were estimated following an appraisal of quality of study samples.
    Results: We found that the most common clinical feature in patients with HAP was fever (82%) followed by purulent respiratory secretions (72%), tachycardia (52%), and crepitations on auscultation (38%). Approximately 86% of cases were found to be culture-positive while others were bacteriologically sterile. Gram-negative bacilli were more commonly isolated (83% Gram-negative vs 17% Gram-positive). The most common organisms isolated were Klebsiella pneumoniae, Citrobacter freundii, Escherichia coli, Acinetobacter, and Pseudomonas aeruginosa. Staphylococcus aureus was isolated from eight specimens and all isolates were susceptible to vancomycin, linezolid, teicoplanin, and tigecycline. Seven isolates were resistant to clindamycin and all 8 were resistant to macrolides and quinolones. Five strains had methicillin resistance indicating a rising burden of 'superbugs'. The most common side involved was the right side and the right middle zone was the most common zone involved. Forty-four percent of cases had a poor outcome and succumbed to the infection.
    Conclusions: HAP places patients at a heightened risk of mortality and manifests a distinctive clinical-microbiological profile. It is advisable to adopt a proactive stance in averting HAI by adhering to robust prophylaxis and management protocols in alignment with regional data and hospital guidelines. Despite the study's constrained sample size, it contributes significant insights specific to the region. This underscores the necessity for further exploration through analogous studies and audits in the northern part of India. Such endeavors have the potential to tailor treatment approaches for patients, ultimately enhancing overall outcomes.
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.50707
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  6. Article: Tinospora cordifolia (Giloy)

    Gupta, Abhishek / Gupta, Priyanka / Bajpai, Gunjan

    Heliyon

    2024  Volume 10, Issue 4, Page(s) e26125

    Abstract: Medicinal herbs are being widely accepted as alternative remedies for preventing various diseases especially in India and other Asian countries. However, most plant-based herbal medicines are not yet being scientifically accepted worldwide. " ...

    Abstract Medicinal herbs are being widely accepted as alternative remedies for preventing various diseases especially in India and other Asian countries. However, most plant-based herbal medicines are not yet being scientifically accepted worldwide. "
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26125
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  7. Article ; Online: Bi-Manual Sensory Discrimination: A Kinesthetic Study.

    Kakade, Suhas / Chaudhuri, Subhasis / Gupta, Abhishek

    IEEE transactions on haptics

    2024  Volume 17, Issue 1, Page(s) 116–121

    Abstract: The ability of humans to perceive and differentiate kinesthetic sensory information significantly influences our daily activities and motor control. This study examines the impact of asynchronous bi-manual discrimination tasks compared to uni-manual ... ...

    Abstract The ability of humans to perceive and differentiate kinesthetic sensory information significantly influences our daily activities and motor control. This study examines the impact of asynchronous bi-manual discrimination tasks compared to uni-manual discrimination tasks on kinesthetic perception. Our study aims to reveal the relationship between kinesthetic perception of haptic signals by examining perceptual thresholds in three different scenarios using (i) the dominant hand, (ii) the non-dominant hand, and (iii) both hands simultaneously to differentiate between two successive signals. Subjects exposed to force signals in these three situations conveyed their perceptions of alterations in signal magnitude after each trial. Subsequently, we applied psychometric functions to the collected responses to determine perceptual thresholds. Our results indicate a substantial difference in threshold values between bi-manual and uni-manual scenarios, with the bi-manual scenario exhibiting higher thresholds, indicating inferior perceptual ability when both hands are simultaneously utilized in two separate discrimination tasks. Furthermore, our investigation reveals distinct perception thresholds between the dominant and non-dominant hands, owing to differences in the perceptual capability of the two hands. These findings provide substantial insight into how the nature of tasks may alter kinesthetic perception, offering implications for the development of haptic interfaces in practical applications.
    MeSH term(s) Humans ; Touch Perception/physiology ; Hand/physiology ; Mechanical Phenomena ; Upper Extremity ; Sensory Thresholds
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ISSN 2329-4051
    ISSN (online) 2329-4051
    DOI 10.1109/TOH.2024.3362352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Body composition parameters as predictors of low back pain in rural homemakers of North India.

    Sengar, Mili / Gupta, Abhishek / Singh, Swati / Mishra, Nandini

    Journal of family medicine and primary care

    2024  Volume 13, Issue 2, Page(s) 512–516

    Abstract: Background: Homemakers are the backbones of families, but in rural India, females suffer from many musculoskeletal problems due to excessive workload in their houses. The objective of the present study is to compare body composition parameters as ... ...

    Abstract Background: Homemakers are the backbones of families, but in rural India, females suffer from many musculoskeletal problems due to excessive workload in their houses. The objective of the present study is to compare body composition parameters as predictors of low back pain (LBP) in nonworking rural homemakers of North India.
    Materials and methods: The study was conducted among 296 homemakers from rural areas of Lucknow district in Uttar Pradesh. Details of LBP and body composition parameters (body mass index, body fat, visceral fat) were taken.
    Results: The prevalence of LBP among homemakers was found to be 15.54%. BMI was found to be a better predictor of LBP than body fat and visceral fat. The risk of LBP is 7.24 times higher in BMI ≥23 than in women with BMI <23. The risk of LBP is 3.67 times more in visceral fat % ≥10% than in women with visceral fat % <10%.
    Conclusion: Age, type of family, socioeconomic status income was identified as risk factors in this population. Maintaining an adequate BMI is essential for the prevention of LBP.
    Language English
    Publishing date 2024-03-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_920_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Making Responsible AI the Norm rather than the Exception

    Gupta, Abhishek

    2021  

    Abstract: This report prepared by the Montreal AI Ethics Institute provides recommendations in response to the National Security Commission on Artificial Intelligence (NSCAI) Key Considerations for Responsible Development and Fielding of Artificial Intelligence ... ...

    Abstract This report prepared by the Montreal AI Ethics Institute provides recommendations in response to the National Security Commission on Artificial Intelligence (NSCAI) Key Considerations for Responsible Development and Fielding of Artificial Intelligence document. The report centres on the idea that Responsible AI should be made the Norm rather than an Exception. It does so by utilizing the guiding principles of: (1) alleviating friction in existing workflows, (2) empowering stakeholders to get buy-in, and (3) conducting an effective translation of abstract standards into actionable engineering practices. After providing some overarching comments on the document from the NSCAI, the report dives into the primary contribution of an actionable framework to help operationalize the ideas presented in the document from the NSCAI. The framework consists of: (1) a learning, knowledge, and information exchange (LKIE), (2) the Three Ways of Responsible AI, (3) an empirically-driven risk-prioritization matrix, and (4) achieving the right level of complexity. All components reinforce each other to move from principles to practice in service of making Responsible AI the norm rather than the exception.

    Comment: A report prepared by the Montreal AI Ethics Institute for the National Security Commission on Artificial Intelligence in response to their Key Considerations for Responsible Development and Fielding of Artificial Intelligence document; 26 pages
    Keywords Computer Science - Computers and Society ; Computer Science - Artificial Intelligence ; Computer Science - Human-Computer Interaction
    Subject code 170
    Publishing date 2021-01-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Book ; Online: On the Target Detection Performance of a Molecular Communication Network with Multiple Mobile Nanomachines

    Sabu, Nithin V. / Gupta, Abhishek K.

    2024  

    Abstract: A network of nanomachines (NMs) can be used to build a target detection system for a variety of promising applications. They have the potential to detect toxic chemicals, infectious bacteria, and biomarkers of dangerous diseases such as cancer within the ...

    Abstract A network of nanomachines (NMs) can be used to build a target detection system for a variety of promising applications. They have the potential to detect toxic chemicals, infectious bacteria, and biomarkers of dangerous diseases such as cancer within the human body. Many diseases and health disorders can be detected early and efficiently treated in the future by utilizing these systems. To fully grasp the potential of these systems, mathematical analysis is required. This paper describes an analytical framework for modeling and analyzing the performance of target detection systems composed of multiple mobile nanomachines of varying sizes with passive/absorbing boundaries. We consider both direct contact detection, in which NMs must physically contact the target to detect it, and indirect sensing, in which NMs must detect the marker molecules emitted by the target. The detection performance of such systems is calculated for degradable and non-degradable targets, as well as mobile and stationary targets. The derived expressions provide various insights, such as the effect of NM density and target degradation on detection probability.
    Keywords Computer Science - Information Theory ; Electrical Engineering and Systems Science - Signal Processing
    Subject code 006
    Publishing date 2024-01-09
    Publishing country us
    Document type Book ; Online
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