LIVIVO - Search results -

Search results

Result 1 - 10 of total 269

Search options

Book: Adolescent cardiac issues

Gupta, Pooja

(Pediatric clinics of North America ; 61,1)

2014

Author's details	ed. Pooja Gupta
Series title	Pediatric clinics of North America ; 61,1 The pediatric clinics of North America
Collection	The pediatric clinics of North America
Language	English
Size	XVIII, 239 S. : Ill., graph. Darst.
Publisher	Elsevier
Publishing place	Philadelphia, Pa. u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT018145363
ISBN	978-0-323-26676-5 ; 0-323-26676-2
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
Um IV Zs 147 -61,1-	verfügbar in Königswinter	Königswinter

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: A Rare Case Report of Dental and Craniofacial Manifestations of Nemaline Myopathy.

Badnaware, Sheetal / Gupta, Pooja

Cureus

2023 Volume 15, Issue 11, Page(s) e49091

Abstract: Any congenital muscular disorder can cause severe dental and craniofacial deformity. The clinicians must understand the aetiology of this muscular disorder to plan the treatment for this condition. Currently, there is limited data available in the ... ...

Abstract	Any congenital muscular disorder can cause severe dental and craniofacial deformity. The clinicians must understand the aetiology of this muscular disorder to plan the treatment for this condition. Currently, there is limited data available in the literature on the dental manifestation of nemaline myopathy. Nemaline myopathy is a type of rare congenital muscular disorder characterized by severe dental and craniofacial deformity. This case report describes the dental and craniofacial manifestations of such diseases in an eight-year-old child who visited the unit of pediatric and preventive dentistry with a chief complaint of irregular placement of teeth and inability to close the mouth.
Language	English
Publishing date	2023-11-20
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.49091
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Restoration of Complicated Crown-Root Fracture in a Primary Incisor with Fragment Reattachment.

Gupta, Pooja / Srivastava, Vinay Kumar / Badnaware, Sheetal

Journal of dentistry for children (Chicago, Ill.)

2024 Volume 91, Issue 1, Page(s) 43–46

Abstract: In traumatic dental injuries in children, due to a lack of maturity to cope with the situation, pain intolerance, amount of treatment procedure, and parental anxiety, simplified and non-invasive treatment procedures, such as biologic restorations, are ... ...

Abstract	In traumatic dental injuries in children, due to a lack of maturity to cope with the situation, pain intolerance, amount of treatment procedure, and parental anxiety, simplified and non-invasive treatment procedures, such as biologic restorations, are useful. Using advanced adhesive material for fragment reattachment provides excellent esthetic results and a positive attitude from the patient and family. The purpose of this case report is to describe the biological restoration of a complicated crown-root fracture of a primary maxillary central incisor with the fragment reattachment technique.
MeSH term(s)	Humans ; Tooth Fractures/therapy ; Tooth Fractures/complications ; Incisor/injuries ; Tooth Crown/injuries ; Tooth, Deciduous/injuries ; Tooth Root/injuries ; Dental Restoration, Permanent/methods ; Dental Bonding/methods ; Composite Resins ; Male ; Child ; Maxilla ; Female ; Resin Cements
Chemical Substances	Composite Resins ; Resin Cements
Language	English
Publishing date	2024-04-26
Publishing country	United States
Document type	Journal Article ; Case Reports
ZDB-ID	390120-8
ISSN	1935-5068 ; 1551-8949 ; 0022-0353
ISSN (online)	1935-5068
ISSN	1551-8949 ; 0022-0353
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 304: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Visually impaired population from low socioeconomic strata and their oral health status: an observational study.

Srivastava, Vinay Kumar / Kumar, Aman / Gupta, Pooja / Bhati, Vaishali

The Journal of clinical pediatric dentistry

2024 Volume 48, Issue 1, Page(s) 138–143

Abstract: A significant portion of the world's population suffers from blindness. Despite being a vital part of systemic health, oral health is neglected in such a population. The present study aimed to determine the oral health status of blind individuals in ... ...

Abstract	A significant portion of the world's population suffers from blindness. Despite being a vital part of systemic health, oral health is neglected in such a population. The present study aimed to determine the oral health status of blind individuals in north India and to identify the factors affecting it. Sixty-nine blind students from a local school for the visually impaired were included in the study. A questionnaire was used to record the basic demographic details and oral habits, followed by an oral examination by a single trained dentist to record dental caries, periodontal status and dental trauma. The prevalence of Dental caries was 63.8% (mean 1.43 ± 1.61). Gingival bleeding on probing (BOP) was found in 60.9% of individuals. Dental trauma prevalence was 23.2%, and harmful oral habits were found in 31.9% of individuals. Individuals experiencing a toothache in the last year had a 1.784 times higher risk of dental caries than those who didn't experience a toothache. Individuals having acquired blindness are 2.411 times more prone to dental trauma in comparison to those suffering from congenital blindness. Blind individuals have poor oral health. Toothache in the last one year is an important risk factor for dental caries in such individuals. Acquired blindness makes a person more susceptible to dental trauma than congenital blindness.
MeSH term(s)	Humans ; Oral Health ; Dental Caries/epidemiology ; Toothache ; Blindness/epidemiology ; Blindness/etiology ; Socioeconomic Factors
Language	English
Publishing date	2024-01-03
Publishing country	Singapore
Document type	Observational Study ; Journal Article
ZDB-ID	1062408-9
ISSN	1053-4628 ; 0145-5508
ISSN	1053-4628 ; 0145-5508
DOI	10.22514/jocpd.2024.015
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1444: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Association of Proliferative Indices With Various Grades of Breast Carcinoma.

Awasthi, Seema / Gupta, Pooja / Mittal, Ankita

Cureus

2023 Volume 15, Issue 7, Page(s) e41865

Abstract: Aims and objectives: Various grades of breast carcinoma and proliferative indices used as nuclear protein Ki-67 and argyrophilic nucleolar organizer regions (AgNOR) are being compared to each other.: Materials and method: In this observational cross- ... ...

Abstract	Aims and objectives: Various grades of breast carcinoma and proliferative indices used as nuclear protein Ki-67 and argyrophilic nucleolar organizer regions (AgNOR) are being compared to each other. Materials and method: In this observational cross-sectional investigation, 42 breast biopsies from questionable breast areas were collected and preserved in formalin and paraffin before the tissue blocks were made. A thorough medical history regarding the breast tumor and thorough physical examination results were recorded. Two sections were produced, one stained with an immunohistochemical marker called Ki-67 and the other with a unique stain called AgNOR. Results: Grade I in Nottingham was found to be highest in subjects with Ki-67 1%, grade II in subjects with Ki-67 1-10%, and grade III in subjects with Ki-67>10%. Therefore, a higher Ki-67 score and a higher Nottingham grade were more closely associated. The mean AgNOR score was determined to be highest in Nottingham grade III and lowest in Nottingham grade I. In contrast to grade I and grade II of carcinoma (CA) breast, where there was no statistically significant association between Ki-67 and AgNOR, grade III of CA breast showed a statistically significant link between Ki-67 and AgNOR. Conclusion: Proliferation has been identified as a distinctive feature of cancer and as a key factor in the prognosis of the disease.
Language	English
Publishing date	2023-07-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.41865
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Integrative analysis of small non-coding RNAs predicts a piRNA/miRNA-CCND1/BRAF/HRH1/ATXN3 regulatory circuit that drives oncogenesis in glioblastoma.

Nayak, Rojalin / Chattopadhyay, Trisha / Gupta, Pooja / Mallick, Bibekanand

Molecular omics

2023 Volume 19, Issue 3, Page(s) 252–261

Abstract: The high-grade astrocytoma, glioblastoma multiforme (GBM), is the most common primary tumour of the brain, known for being aggressive and developing drug resistance. The non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and Piwi-interacting RNAs ( ... ...

Abstract	The high-grade astrocytoma, glioblastoma multiforme (GBM), is the most common primary tumour of the brain, known for being aggressive and developing drug resistance. The non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and Piwi-interacting RNAs (piRNAs), have critical functions in tumorigenesis and cancer drug resistance. Hence, we profiled miRNAs, piRNAs, and genes in U-87 MG GBM cells by next-generation sequencing and performed target prediction, pathway enrichment, protein-protein interaction, co-expression studies, and qRT-PCR validations to predict their possible roles in the malignancy. The study identified 335 miRNAs, 665 piRNAs, and 4286 genes differentially expressed (DE) in GBM. Among them 128 DE genes (DEGs) were targeted by both miRNAs and piRNAs, while 1817 and 192 were targeted solely by miRNAs or piRNAs, respectively. Interestingly, all the DEG targets enriched in cancer processes were overexpressed in GBM. Among these, BRAF was solely targeted by two piRNAs and this was found to be co-expressed with 19 sole targets of 5 miRNAs, including CCND1, and both were found to regulate cell proliferation in cancer. We conjectured that upregulated HRH1 and ATXN3 were targeted by both piRNAs and miRNAs, and along with BRAF and CCND1 might induce cell proliferation in GBM through G-protein-coupled receptor or Akt signalling pathways due to downregulation of the respective targeting small RNAs. These targets were also linked to the progression and overall survival of GBM patients, suggesting that they could be used as biomarkers. Overall, this study has identified a few novel ncRNA targets, which might aid in a better understanding of GBM pathogenesis.
MeSH term(s)	Humans ; MicroRNAs/genetics ; Glioblastoma/genetics ; Glioblastoma/pathology ; Piwi-Interacting RNA ; Proto-Oncogene Proteins B-raf ; RNA, Untranslated/genetics ; Carcinogenesis ; Cell Transformation, Neoplastic ; Ataxin-3 ; Repressor Proteins ; Cyclin D1/genetics
Chemical Substances	MicroRNAs ; Piwi-Interacting RNA ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; RNA, Untranslated ; ATXN3 protein, human (EC 3.4.19.12) ; Ataxin-3 (EC 3.4.19.12) ; Repressor Proteins ; BRAF protein, human (EC 2.7.11.1) ; CCND1 protein, human ; Cyclin D1 (136601-57-5)
Language	English
Publishing date	2023-03-27
Publishing country	England
Document type	Journal Article
ISSN	2515-4184
ISSN (online)	2515-4184
DOI	10.1039/d2mo00245k
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Cognition and cardiovascular comorbidities among older adults in primary care in West India.

Dhikav, Vikas / Jadeja, Bhargavi / Gupta, Pooja

Journal of neurosciences in rural practice

2023 Volume 14, Issue 2, Page(s) 230–234

Abstract: Objectives: Cardiovascular risk factors (e.g., diabetes and hypertension) are comorbidities associated with cognitive impairment. The present study was planned to study the relationship between cardiovascular risk factors and cognitive impairment using ... ...

Abstract	Objectives: Cardiovascular risk factors (e.g., diabetes and hypertension) are comorbidities associated with cognitive impairment. The present study was planned to study the relationship between cardiovascular risk factors and cognitive impairment using General Practitioner assessment of Cognition (GPCOG) scale, which is easy to use scale in the primary care. Materials and methods: A total of 350 older adults (mean age=66.71 ± 6.53 years; M:F = 220:130) among 3000 who reported to the primary care center in West India were screened. Cardiovascular risk factors were assessed based on written medical records. GPCOG was used for cognitive screening of those over the age of 60 with subjective memory complaints. Results: Frequency of cardiovascular (CV) risk factors in those with cognitive impairment was 46.2% ( Conclusion: A higher CV risk factors were observed among those with cognitive impairment compared to those cognitively normal older adults in the primary care.
Language	English
Publishing date	2023-01-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2601242-X
ISSN	0976-3155 ; 0976-3147
ISSN (online)	0976-3155
ISSN	0976-3147
DOI	10.25259/JNRP_23_2022
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Antigen loss following CAR-T cell therapy: Mechanisms, implications, and potential solutions.

Mishra, Archana / Maiti, Rituparna / Mohan, Prafull / Gupta, Pooja

European journal of haematology

2023 Volume 112, Issue 2, Page(s) 211–222

Abstract: Chimeric Antigen Receptor T-cell (CAR-T cell) therapy has emerged as a groundbreaking immunotherapeutic approach for treating various hematological malignancies. CAR-T cells are engineered to express synthetic receptors that target specific antigens on ... ...

Abstract	Chimeric Antigen Receptor T-cell (CAR-T cell) therapy has emerged as a groundbreaking immunotherapeutic approach for treating various hematological malignancies. CAR-T cells are engineered to express synthetic receptors that target specific antigens on cancer cells, leading to their eradication. While the therapy has shown remarkable efficacy, a significant challenge that has been observed in 30%-70% of patients showing recurrent disease is antigen loss or downregulation. We searched PubMed/MEDLINE, EMBASE, and Google scholar for articles on antigen loss/escape following Chimeric antigen receptor T-cell therapy in malignancies. Antigen loss refers to the loss or reduction in the expression of the target antigen on cancer cells, rendering CAR-T cells ineffective. This phenomenon poses a significant clinical concern, as it can lead to disease relapse and limited treatment options. This review explores the mechanisms underlying antigen loss following CAR-T cell therapy, its implications on treatment outcomes, and potential strategies to overcome the problem.
MeSH term(s)	Humans ; Receptors, Chimeric Antigen ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; T-Lymphocytes ; Neoplasm Recurrence, Local ; Immunotherapy, Adoptive/adverse effects ; Cell- and Tissue-Based Therapy
Chemical Substances	Receptors, Chimeric Antigen ; Receptors, Antigen, T-Cell
Language	English
Publishing date	2023-09-13
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	392482-8
ISSN	1600-0609 ; 0902-4441
ISSN (online)	1600-0609
ISSN	0902-4441
DOI	10.1111/ejh.14101
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 323: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Role of Transesophageal Echocardiography in the Diagnosis of Coronary Ischemia in a Patient with History of Ross Procedure.

Sebastian, Joseph / Dawdy, John / Ala, Chandra / Zehr, Kenton / Gupta, Pooja / Afonso, Luis

CASE (Philadelphia, Pa.)

2024 Volume 8, Issue 3Part A, Page(s) 109–116

Language	English
Publishing date	2024-03-08
Publishing country	United States
Document type	Case Reports
ISSN	2468-6441
ISSN (online)	2468-6441
DOI	10.1016/j.case.2023.12.021
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: TarpiD, a database of putative and validated targets of piRNAs.

Gupta, Pooja / Das, Gourab / Chattopadhyay, Trisha / Ghosh, Zhumur / Mallick, Bibekanand

Molecular omics

2023 Volume 19, Issue 9, Page(s) 706–713

Abstract: Piwi-interacting RNAs (piRNAs) are a novel class of 18-36 nts long small non-coding single-stranded RNAs that play crucial roles in a wide array of critical biological activities besides maintaining genome integrity by transposon silencing. piRNAs ... ...

Abstract	Piwi-interacting RNAs (piRNAs) are a novel class of 18-36 nts long small non-coding single-stranded RNAs that play crucial roles in a wide array of critical biological activities besides maintaining genome integrity by transposon silencing. piRNAs influence biological processes and pathways by regulating gene expression at transcriptional and post-transcriptional level. Studies have reported that piRNAs silence various endogenous genes post-transcriptionally by binding to respective mRNAs through interaction with the PIWI proteins. Several thousands of piRNAs have been discovered in animals, but their functions remain largely undiscovered owing to a lack of proper guiding principles of piRNA targeting or diversity in targeting patterns amongst piRNAs from the same or different species. Identification of piRNA targets is essential for deciphering their functions. There are a few tools and databases on piRNAs, but there are no systematic and exclusive repositories to obtain information on target genes regulated by piRNAs and other related information. Hence, we developed a user-friendly database named TarpiD (Targets of piRNA Database) that offers comprehensive information on piRNA and its targets, including their expression, methodologies (high-throughput or low-throughput) for target identification/validation, cells/tissue types, diseases, target gene regulation types, target binding regions, and key functions driven by piRNAs through target gene interactions. The contents of TarpiD are curated from the published literature and enable users to search and download the targets of a particular piRNA or the piRNAs that target a specific gene for use in their research. This database harbours 28 682 entries of piRNA-target interactions supported by 15 methodologies reported in hundreds of cell types/tissues from 9 species. TarpiD will be a valuable resource for a better understanding of the functions and gene-regulatory mechanisms mediated by piRNAs. TarpiD is freely accessible for academic use at https://tarpid.nitrkl.ac.in/tarpid_db/.
MeSH term(s)	Animals ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Piwi-Interacting RNA ; Gene Expression Regulation ; Proteins/metabolism
Chemical Substances	RNA, Small Interfering ; Piwi-Interacting RNA ; Proteins
Language	English
Publishing date	2023-10-30
Publishing country	England
Document type	Journal Article
ISSN	2515-4184
ISSN (online)	2515-4184
DOI	10.1039/d3mo00098b
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED