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  1. Article: Propranolol for Vascular Anomalies: Efficacy and Complications in Pediatric Patients.

    Gupta, Rahul

    Journal of Indian Association of Pediatric Surgeons

    2023  Volume 28, Issue 3, Page(s) 194–205

    Abstract: Context: Congenital vascular anomalies are classically subdivided into vascular tumors and vascular malformations. The role of propranolol in the regression of infantile hemangioma (IH), a vascular tumor, is well establishe.: Aims: This study aimed ... ...

    Abstract Context: Congenital vascular anomalies are classically subdivided into vascular tumors and vascular malformations. The role of propranolol in the regression of infantile hemangioma (IH), a vascular tumor, is well establishe.
    Aims: This study aimed to analyze the therapeutic efficacy and complications associated with oral propranolol and adjuvant therapy in the treatment of vascular anomalies.
    Settings and design: A prospective interventional study was undertaken over 10 years duration extending from 2012 to 2022 at a tertiary care teaching institute.
    Materials and methods: All children with cutaneous hemangiomas and lymphatic and venous malformations under 12 years of age, except those with contraindications for administration of propranolol, were included in the study.
    Results: Out of 382 patients, there were 159 males and 223 females (male: female = 1:1.4). The majority (53.66%) were between ≥3 months and 1 year. There were 481 lesions in 382 patients. There were 348 patients with IH, and 11 were congenital hemangiomas (CHs). There were 23 patients with vascular malformations; lymphatic malformation (
    Conclusion: The study validates the use of propranolol hydrochloride as the first-line agent for the treatment of IHs and congenital hemangiomas. It may have an additive role in lymphatic malformations, and venous malformations, as a part of a multimodality treatment approach for vascular malformations.
    Language English
    Publishing date 2023-05-02
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_117_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Transanal Protrusion of Nonischemic Compound Intussusception.

    Gupta, Rahul

    Journal of Indian Association of Pediatric Surgeons

    2022  Volume 27, Issue 4, Page(s) 509–510

    Language English
    Publishing date 2022-07-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_126_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Could anakinra outmatch dexamethasone/tocilizumab in COVID-19?

    Gupta, Rahul

    Bulletin of the National Research Centre

    2022  Volume 46, Issue 1, Page(s) 100

    Abstract: The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe COVID-19. These severe patients have similar ...

    Abstract The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe COVID-19. These severe patients have similar clinical manifestations with patients suffering from certain auto-inflammatory disorders and cytokine storm syndromes. Interestingly, anakinra (blocking both IL-1α and IL-1β) has shown promises in treating these patients with hyperinflammatory disorders, sepsis with multiorgan failures. Another inflammasome, AIM2, involved in production of IL-1 has also been found to be implicated in COVID-19. IL-1β, a known procoagulant, causes induction of tissue factor with increasing vascular endothelial permeability loss ensuing in hypercoagulability-one of the cardinal features of the disease. Hence, anakinra a 17kD recombinant human IL-1 receptor antagonist, used widely in Rheumatoid Arthritis treatments might prove efficacious in attenuating the hyperinflammatory state of the disease. Indeed, some of the controlled clinical trials have shown anakinra to effectively decrease mortality and hospital stay. Targeted cytokine blocking are always preferable in comparison with non-specific blocking (steroids) as it is more restrained with the chances of dampening of systemic immune system being much less. Early cell death and neutrophil migration have been one of the pivotal events in COVID-19 pathogenesis. Hence, suPAR levels which measures IL-1α (necroptosis) and S100A8/A9 (neutrophil migration) can perhaps be a good early biomarker predicting the disease progression. Lastly and importantly, as the vaccines are raised against spike protein and the different variants of concern are known to evade the neutralizing antibodies by varying degrees, it will be deserving to assess anakinra, against the variants of concern as an immunomodulatory drug.
    Language English
    Publishing date 2022-04-13
    Publishing country Germany
    Document type Journal Article
    ISSN 2522-8307
    ISSN (online) 2522-8307
    DOI 10.1186/s42269-022-00781-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: E-agriculture

    Gupta, Rahul

    concepts and applications

    (Icfai books)

    2008  

    Author's details ed. by Rahul Gupta
    Series title Icfai books
    Language English
    Size IX, 190 S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Icfai Univ. Press
    Publishing place Hyderabad
    Publishing country India
    Document type Book
    HBZ-ID HT016117217
    ISBN 978-81-314-1596-2 ; 81-314-1596-1
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    098/1241 available for loan (reading room) Freihandmagazin (U1)

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  5. Book ; Online: Quantifying the Uncertainty of Sensitivity Coefficients Computed from Uncertain Compound Admittance Matrix and Noisy Grid Measurements

    Gupta, Rahul

    2023  

    Abstract: The power-flow sensitivity coefficients (PFSCs) are widely used in the power system for expressing linearized dependencies between the controlled (i.e., the nodal voltages, lines currents) and control variables (e.g., active and reactive power injections, ...

    Abstract The power-flow sensitivity coefficients (PFSCs) are widely used in the power system for expressing linearized dependencies between the controlled (i.e., the nodal voltages, lines currents) and control variables (e.g., active and reactive power injections, transformer tap positions, etc.). The PFSCs are often computed by knowing the compound admittance matrix of a given network and the grid states. However, when the branch parameters (or admittance matrix) are inaccurate or known with limited accuracy, the computed PFSCs can not be relied upon. Uncertain PFSCs, when used in control, can lead to infeasible control set-points. In this context, this paper presents a method to quantify the uncertainty of the PFSCs from uncertain branch parameters and noisy grid-state measurements that can be used for formulating safe control schemes. We derive an analytical expression using the error-propagation principle. The developed tool is numerically validated using Monte Carlo simulations.

    Comment: 4 pages, Accepted in IEEE Transactions on Instrumentation & Measurement Letter
    Keywords Electrical Engineering and Systems Science - Systems and Control
    Subject code 621
    Publishing date 2023-12-14
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article ; Online: Anakinra: a silver lining in COVID-19?

    Gupta, Rahul

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 598

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Interleukin 1 Receptor Antagonist Protein ; Interleukin-1 ; Pandemics ; Pneumonia, Viral ; Respiratory Insufficiency ; SARS-CoV-2
    Chemical Substances Interleukin 1 Receptor Antagonist Protein ; Interleukin-1
    Keywords covid19
    Language English
    Publishing date 2020-10-06
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03312-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The double edged interferon riddle in COVID-19 pathogenesis.

    Gupta, Rahul

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 631

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Interferon beta-1a ; Interferons ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Chemical Substances Interferons (9008-11-1) ; Interferon beta-1a (XRO4566Q4R)
    Keywords covid19
    Language English
    Publishing date 2020-11-01
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03337-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Newborn Umbilical Cord Stump Myiasis: Report of an Earliest Presentation.

    Sharma, Shyam Bihari / Gupta, Rahul

    Journal of Indian Association of Pediatric Surgeons

    2023  Volume 28, Issue 1, Page(s) 86–87

    Language English
    Publishing date 2023-01-10
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_125_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Outcomes of renin-angiotensin inhibitors following transcatheter aortic valve implantation.

    Hosseinpour, Alireza / Gupta, Rahul

    Clinical cardiology

    2023  Volume 47, Issue 2, Page(s) e24187

    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement/adverse effects ; Angiotensins ; Renin ; Renin Inhibitors ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Treatment Outcome ; Risk Factors ; Heart Valve Prosthesis
    Chemical Substances Angiotensins ; Renin (EC 3.4.23.15) ; Renin Inhibitors
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Letter
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.24187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1423: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Barbed Suspension Bridge Pharyngoplasty: Introducing a Novel Technique for Barbed Pharyngoplasty.

    Agrawal, Vikas K / Gupta, Rahul R

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2023  Volume 76, Issue 1, Page(s) 669–675

    Abstract: Surgical management of Obstructive Sleep Apnea (OSA) and Snoring has undergone many major and minor changes over a period of last decade. The most common surgical approach for OSA is uvulopalatopharyngoplasty (Stuck et al. in Sleep Med 50:152-165, 2018). ...

    Abstract Surgical management of Obstructive Sleep Apnea (OSA) and Snoring has undergone many major and minor changes over a period of last decade. The most common surgical approach for OSA is uvulopalatopharyngoplasty (Stuck et al. in Sleep Med 50:152-165, 2018). The main goals of treatment of OSA are to decrease the risk of deleterious health effects and improve quality of sleep (Evans et al. in Otolaryngol Clin North Am 53: 319-328, 2020). Since bimanual surgical techniques in the depth of oral cavity have been tricky, search for a less demanding & easy to learn technique is always on. The surgical technique should also provide long term results with manageable complications. Barbed suture has been in sporadic use for the last decade amongst sleep apnea surgeons for its advantage of knotless application and distributed suture tension. However, the barbed suture which has been used is absorbable and is used only to close the surgical wound on the soft palate. In this paper we are describing our technique of using the 3-0 Polybutester non absorbable barbed suture to perform a novel technique of palatal surgery, in which we suspend the lower part of the soft palate permanently as a suspension bridge between the right and left Pterygomandibular raphae, so that the lower part of the soft palate cannot move posteriorly to touch the posterior pharyngeal wall preventing airway obstruction whereas it can still move superiorly freely while swallowing or during phonation. This technique can prove to be a technically less demanding one which provides excellent long-term results in snoring and OSA with manageable complications.
    Language English
    Publishing date 2023-10-10
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-04246-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5300: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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