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  1. Article: Pimozide-induced tardive dyskinesia in the treatment of delusions of infestation.

    Gutierrez, Rodrigo A / Smith, Payton / Kranyak, Allison / Davis, Mitchell / Koo, John

    JAAD case reports

    2024  Volume 45, Page(s) 71–73

    Language English
    Publishing date 2024-01-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2024.01.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Transient dermatomyositis-like reaction following COVID-19 messenger RNA vaccination.

    Gutierrez, Rodrigo A / Connolly, Kari / Gross, Andrew / Haemel, Anna

    JAAD case reports

    2023  Volume 37, Page(s) 128–130

    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.05.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Drug rash with eosinophilia and systemic symptoms to anti-tuberculosis therapy: A retrospective review of inpatients at an academic medical centre in the United States.

    Gutierrez, Rodrigo A / Kazmi, Maha / Fox, Lindy / Shinkai, Kanade / Arakaki, Ryan / Dobry, Allison / Haemel, Anna

    Skin health and disease

    2024  Volume 4, Issue 2, Page(s) e337

    Abstract: This retrospective cohort study analyzes the presentation, diagnosis, and treatment outcomes of patients who developed drug rash with eosinophilia and systemic symptoms (DRESS) to tuberculosis (TB) therapy in a TB non-endemic region. Anti-TB agents ... ...

    Abstract This retrospective cohort study analyzes the presentation, diagnosis, and treatment outcomes of patients who developed drug rash with eosinophilia and systemic symptoms (DRESS) to tuberculosis (TB) therapy in a TB non-endemic region. Anti-TB agents represented 7.5% of all antimicrobial-induced DRESS cases, and rifampin was the most commonly implicated agent among drugs used to treat TB.
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ISSN 2690-442X
    ISSN (online) 2690-442X
    DOI 10.1002/ski2.337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Molecular mechanisms underlying nitrate responses in plants.

    Lamig, Liliana / Moreno, Sebastián / Álvarez, José M / Gutiérrez, Rodrigo A

    Current biology : CB

    2022  Volume 32, Issue 9, Page(s) R433–R439

    Abstract: Nitrate is an important source of inorganic nitrogen. Nitrate modulates many plant metabolic, physiological, and developmental processes. This minireview highlights recent findings on the intricate molecular wiring that allows plants to adapt to ... ...

    Abstract Nitrate is an important source of inorganic nitrogen. Nitrate modulates many plant metabolic, physiological, and developmental processes. This minireview highlights recent findings on the intricate molecular wiring that allows plants to adapt to environmental nitrate conditions. We focus on the role of regulatory pathways and their components - transporters, receptors, second messengers, kinases, and transcription factors - in mediating plant metabolic and developmental responses to nitrate. Work is still needed to identify missing components of the nitrate signaling pathway and their interplay with known and well-characterized master regulators and to validate their molecular interactions to explain the complexity of phenotypical responses to nitrate. Understanding how plants perceive nitrate and transduce it into responses at the molecular level is crucial to optimize nitrogen-use efficiency, improve crop yield and mitigate the adverse environmental impacts of fertilizer overuse in a changing world.
    MeSH term(s) Nitrates ; Nitrogen/metabolism ; Plant Physiological Phenomena ; Plants/genetics ; Plants/metabolism ; Transcription Factors/metabolism
    Chemical Substances Nitrates ; Transcription Factors ; Nitrogen (N762921K75)
    Language English
    Publishing date 2022-04-22
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2022.03.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Genomic Footprinting Analyses from DNase-seq Data to Construct Gene Regulatory Networks.

    Moyano, Tomás C / Gutiérrez, Rodrigo A / Alvarez, José M

    Methods in molecular biology (Clifton, N.J.)

    2021  Volume 2328, Page(s) 25–46

    Abstract: Chromatin accessibility is directly linked with transcription in eukaryotes. Accessible regions associated with regulatory proteins are highly sensitive to DNase I digestion and are termed DNase I hypersensitive sites (DHSs). DHSs can be identified by ... ...

    Abstract Chromatin accessibility is directly linked with transcription in eukaryotes. Accessible regions associated with regulatory proteins are highly sensitive to DNase I digestion and are termed DNase I hypersensitive sites (DHSs). DHSs can be identified by DNase I digestion, followed by high-throughput DNA sequencing (DNase-seq). The single-base-pair resolution digestion patterns from DNase-seq allows identifying transcription factor (TF) footprints of local DNA protection that predict TF-DNA binding. The identification of differential footprinting between two conditions allows mapping relevant TF regulatory interactions. Here, we provide step-by-step instructions to build gene regulatory networks from DNase-seq data. Our pipeline includes steps for DHSs calling, identification of differential TF footprints between treatment and control conditions, and construction of gene regulatory networks. Even though the data we used in this example was obtained from Arabidopsis thaliana, the workflow developed in this guide can be adapted to work with DNase-seq data from any organism with a sequenced genome.
    MeSH term(s) Arabidopsis/genetics ; Arabidopsis/metabolism ; Chromatin/genetics ; Chromatin/metabolism ; Chromosome Mapping/methods ; DNA Footprinting/methods ; Deoxyribonuclease I/metabolism ; Gene Expression Regulation/genetics ; Gene Regulatory Networks/genetics ; Genomics ; High-Throughput Nucleotide Sequencing/methods ; Protein Binding ; Software ; Transcription Factors/genetics ; Transcription Factors/metabolism
    Chemical Substances Chromatin ; Transcription Factors ; Deoxyribonuclease I (EC 3.1.21.1)
    Language English
    Publishing date 2021-07-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-1534-8_3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: BrumiR: A toolkit for de novo discovery of microRNAs from sRNA-seq data.

    Moraga, Carol / Sanchez, Evelyn / Ferrarini, Mariana Galvão / Gutierrez, Rodrigo A / Vidal, Elena A / Sagot, Marie-France

    GigaScience

    2022  Volume 11

    Abstract: MicroRNAs (miRNAs) are small noncoding RNAs that are key players in the regulation of gene expression. In the past decade, with the increasing accessibility of high-throughput sequencing technologies, different methods have been developed to identify ... ...

    Abstract MicroRNAs (miRNAs) are small noncoding RNAs that are key players in the regulation of gene expression. In the past decade, with the increasing accessibility of high-throughput sequencing technologies, different methods have been developed to identify miRNAs, most of which rely on preexisting reference genomes. However, when a reference genome is absent or is not of high quality, such identification becomes more difficult. In this context, we developed BrumiR, an algorithm that is able to discover miRNAs directly and exclusively from small RNA (sRNA) sequencing (sRNA-seq) data. We benchmarked BrumiR with datasets encompassing animal and plant species using real and simulated sRNA-seq experiments. The results demonstrate that BrumiR reaches the highest recall for miRNA discovery, while at the same time being much faster and more efficient than the state-of-the-art tools evaluated. The latter allows BrumiR to analyze a large number of sRNA-seq experiments, from plants or animal species. Moreover, BrumiR detects additional information regarding other expressed sequences (sRNAs, isomiRs, etc.), thus maximizing the biological insight gained from sRNA-seq experiments. Additionally, when a reference genome is available, BrumiR provides a new mapping tool (BrumiR2reference) that performs an a posteriori exhaustive search to identify the precursor sequences. Finally, we also provide a machine learning classifier based on a random forest model that evaluates the sequence-derived features to further refine the prediction obtained from the BrumiR-core. The code of BrumiR and all the algorithms that compose the BrumiR toolkit are freely available at https://github.com/camoragaq/BrumiR.
    MeSH term(s) Animals ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Software ; Sequence Analysis, RNA/methods ; High-Throughput Nucleotide Sequencing/methods ; RNA, Small Untranslated/genetics
    Chemical Substances MicroRNAs ; RNA, Small Untranslated
    Language English
    Publishing date 2022-10-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2708999-X
    ISSN 2047-217X ; 2047-217X
    ISSN (online) 2047-217X
    ISSN 2047-217X
    DOI 10.1093/gigascience/giac093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cutaneous and systemic plasmacytosis with concurrent lymphoid hyperplasia.

    Gutierrez, Rodrigo A / Jacobson, Rebecca / Dawson, Annelise / Haemel, Anna / North, Jeffrey

    Journal of cutaneous pathology

    2022  Volume 50, Issue 5, Page(s) 379–382

    MeSH term(s) Humans ; Hyperplasia/pathology ; Skin/pathology ; Skin Diseases/pathology ; Neoplasms/pathology ; Plasma Cells/pathology
    Language English
    Publishing date 2022-11-10
    Publishing country United States
    Document type Letter
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.14338
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1043: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Tuberculid reactions: A multi-institution cohort study from 2 academic medical centers in the United States.

    Jacobson, Rebecca / Gutierrez, Rodrigo A / Ghatnekar, Shilpa / Virji, Azan Z / Schwartz, Brian S / Gensler, Lianne S / Haemel, Anna / Frangos, Jason E

    JAAD international

    2023  Volume 13, Page(s) 68–70

    Language English
    Publishing date 2023-08-19
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3287
    ISSN (online) 2666-3287
    DOI 10.1016/j.jdin.2023.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cutaneous tuberculosis: A multi-institution cohort study from 2 academic medical centers in the United States.

    Gutierrez, Rodrigo A / Jacobson, Rebecca / Ghatnekar, Shilpa / Virji, Azan Z / Schwartz, Brian S / Gensler, Lianne S / Haemel, Anna / Frangos, Jason E

    JAAD international

    2023  Volume 13, Page(s) 63–65

    Language English
    Publishing date 2023-08-12
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3287
    ISSN (online) 2666-3287
    DOI 10.1016/j.jdin.2023.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Emerging Players in the Nitrate Signaling Pathway.

    Armijo, Grace / Gutiérrez, Rodrigo A

    Molecular plant

    2017  Volume 10, Issue 8, Page(s) 1019–1022

    MeSH term(s) Calcium/metabolism ; Nitrates/metabolism ; Signal Transduction ; Transcription Factors/metabolism
    Chemical Substances Nitrates ; Transcription Factors ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2017-07-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2393618-6
    ISSN 1752-9867 ; 1674-2052
    ISSN (online) 1752-9867
    ISSN 1674-2052
    DOI 10.1016/j.molp.2017.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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