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  1. Book ; Online: La práctica pedagógica: un espacio de formación para futuros formadores

    Muñoz Galíndez, Efraín / Escobar Gutiérrez, Gloria Milena / Torres Rojas, Ingrid Selene / Cano Quintero, María Constanza / Giraldo García, Luz Karime

    2020  

    Keywords Educational strategies & policy ; Práctica pedagógica ; Docentes en formación ; Interdisciplinariedad ; Educación infantil
    Language 0|s
    Size 1 electronic resource (152-169 pages)
    Publisher Universidad Santiago de Cali
    Publishing place Colombia
    Document type Book ; Online
    Note Spanish ; Open Access
    HBZ-ID HT021616972
    ISBN 978-958-5583-88-7 ; 958-5583-88-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Perspectivas de la enseñanza en educación infantil

    Sánchez Borrero, Ana Milena / Bonilla Campo, Constanza / Cuartas Montero, Deisy Liliana / Monroy Machado, Edilson / Muñoz Galíndez, Efraín / Escobar Gutiérrez, Gloria Milena / González Valencia, Heriberto / Torres Rojas, Ingrid Selene / Villota Enríquez, Jakeline Amparo / Cano Moya, Johanna Lorena / Marcela, Duarte Herrera / Miranda Corzo, María Claudia / Villota Enríquez, Maribel Deicy / Salamanca Alarcón, Mayerly / Cuesta Ordoñez, Miguel Enrique / Fajardo Torres, Neiver / Lozano, Pablo Cesar / Caicedo Bahamonde, Virginia / Cano Quintero, María Constanza /
    Giraldo García, Luz Karime

    2020  

    Keywords Educational strategies & policy ; Lenguaje ; Primera infancia ; Herramientas tecnológicas y formación de profesores ; Aprendizaje activo ; Afrocolombianos ; Indígenas ; Diversidad ; Pedagogía infantil ; Etnoeducación ; Comunidad ; Identidad cultural
    Language 0|s
    Size 1 electronic resource (1-198 pages)
    Publisher Universidad Santiago de Cali
    Publishing place Colombia
    Document type Book ; Online
    Note Spanish ; Open Access
    HBZ-ID HT021613984
    ISBN 978-958-5583-88-7 ; 958-5583-88-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Impact of the Covid-19 epidemic on a US sample of patients with myasthenia gravis.

    Gutierrez, Gloria / Girma, Helen / Kuhnell, Pierce / Macaluso, Maurizio / Kaminski, Henry J

    Therapeutic advances in rare disease

    2022  Volume 3, Page(s) 26330040221082673

    Abstract: Introduction: The Covid-19 pandemic has devastated the world and demonstrated the inadequacy of health care in the United States. To assess its impact, the Rare Disease Clinical Research Network conducted a survey to assess the pandemic on the rare ... ...

    Abstract Introduction: The Covid-19 pandemic has devastated the world and demonstrated the inadequacy of health care in the United States. To assess its impact, the Rare Disease Clinical Research Network conducted a survey to assess the pandemic on the rare disease community of patients, including those with myasthenia gravis (MG).
    Methods: A cross-sectional survey was designed to target people or their care givers who live in the United States, have a rare disease, and are under 90 years of age. Respondents logged onto a dedicated web page and completed the survey online, which requested demographic, disease-specific, drug treatment, and symptom information as well as assessment of Covid-19 impact on them. The survey was open from May 2020 to December 2020.
    Results: Five hundred ninety-four with self-reported myasthenia gravis completed the survey, which was the largest number of respondents. Sixty percent of respondents were women with a mean age of 60 years. Eighty-nine percent identified as White. Respondents did not appreciate a worsening of symptoms after the pandemic. Only 7 respondents reported the diagnosis of Covid-19 but 11% indicated they had difficulty accessing care at the time of the survey.
    Discussion and conclusion: Patients with MG complained of worse access to medical care during the early months of the pandemic, including challenges in diagnosis of suspected Covid-19 infection. A major limitation of the survey is its inability to access minority populations. Nevertheless, the results of the Rare Disease Clinical Research Network (RCDRN) survey of patients with MG provide clear evidence that the pandemic has demonstrated the deficiencies in US healthcare.
    Language English
    Publishing date 2022-03-10
    Publishing country England
    Document type Journal Article
    ISSN 2633-0040
    ISSN (online) 2633-0040
    DOI 10.1177/26330040221082673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: From parallel to partnership.

    Orr, Debra E / Bravo Gutiérrez, Gloria / Fette, Don

    Leadership in health services (Bradford, England)

    2019  Volume 32, Issue 4, Page(s) 493–508

    Abstract: Purpose: In the USA, there has recently been an unprecedented convergence of complementary/alternative medicine (CAM) with mainstream biomedical care. This confluence may lead to a deeply rooted philosophical conflict. This qualitative study works to ... ...

    Abstract Purpose: In the USA, there has recently been an unprecedented convergence of complementary/alternative medicine (CAM) with mainstream biomedical care. This confluence may lead to a deeply rooted philosophical conflict. This qualitative study works to identify factors that health-care leaders can use, which will build a pathway to greater integrative practice between medical doctors and CAM practitioners - from parallel existence to partnership - by examining the tensions between biomedical medicine and naturopathic medicine. The purpose of this study is to offer short-term suggestions for partnership and long-term recommendations for better understanding.
    Design/methodology/approach: An original qualitative study using semi-structured with CAM practitioners and biomedical practitioners.
    Findings: Areas of conflict that are preventing synergy are identified and a pathway for health-care leaders to follow to create greater integration and partnerships is suggested.
    Research limitations/implications: This is a qualitative and exploratory study that has significant limitations on generalizability.
    Practical implications: This study suggest steps that both types of health-care practitioners can take to increase their success at working together on an individual level, a group level, an organizational level and on an industry-wide basis, as well as provide a specific pathway to create greater integrative practice for health-care leaders.
    Social implications: The results indicate that stronger partnerships between different types of medical practitioners increase patient choice, patient satisfaction and outcomes.
    Originality/value: Increasing interested in CAM modalities is driving more contact between CAM practitioners and biomedical practitioners. This contact is best established in partnership between practitioners rather than in parallel. This original research outlines the sources of conflict and provides recommendations for encouraging greater synergy.
    MeSH term(s) Attitude of Health Personnel ; Complementary Therapies ; Health Personnel ; Humans ; Physicians ; Qualitative Research
    Language English
    Publishing date 2019-07-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2279996-5
    ISSN 1751-1887 ; 1751-1879 ; 1366-0756
    ISSN (online) 1751-1887
    ISSN 1751-1879 ; 1366-0756
    DOI 10.1108/LHS-12-2018-0063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Bioprocess intensification for acetone-butanol-ethanol fermentation from brewer's spent grain: Fed-batch strategies coupled with in-situ gas stripping

    Plaza, Pedro E. / Coca, Mónica / Yagüe, Susana Lucas / Gutiérrez, Gloria / Rochón, Eloísa / García-Cubero, M. Teresa

    Biomass and bioenergy. 2022 Jan., v. 156

    2022  

    Abstract: A fed-batch ABE fermentation process coupled with in-situ gas-stripping to mitigate butanol toxicity was investigated. Two feeding strategies were compared: pulses of sugars and continuous feeding of the liquid released in the dilute acid pretreatment of ...

    Abstract A fed-batch ABE fermentation process coupled with in-situ gas-stripping to mitigate butanol toxicity was investigated. Two feeding strategies were compared: pulses of sugars and continuous feeding of the liquid released in the dilute acid pretreatment of brewer's spent grain. The concentrations of butanol (13.2 g L⁻¹ total and 50 g L⁻¹ average in the condensates for glucose pulse feeding) were higher than those obtained under batch conditions, showing that in-situ gas-stripping can relieve butanol toxicity. The continuous feeding of the fed-batch reactor produced similar butanol concentrations (10.2 g L⁻¹ total and 65 g L⁻¹ in the condensates), more stable concentrations of solvents in the condensates and enhanced monosaccharides uptake (99.1%) in comparison with the pulse feeding strategy. The efficient utilization of the enzymatic and pretreatment hydrolysates in the same fed-batch reactor is an integrated approach that could reduce capital and operating costs. The mathematical model proposed showed good performance to predict concentrations in the fermentation broth.
    Keywords bioenergy ; biomass ; bioprocessing ; butanol ; capital ; culture media ; fermentation ; glucose ; liquids ; mathematical models ; spent grains ; toxicity
    Language English
    Dates of publication 2022-01
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1090121-8
    ISSN 0961-9534
    ISSN 0961-9534
    DOI 10.1016/j.biombioe.2021.106327
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 5470: Show issues

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  6. Article: Inheritance of Yield Components and Morphological Traits in Avocado cv. Hass From "Criollo" "Elite Trees"

    Cañas-Gutiérrez, Gloria Patricia / Sepulveda-Ortega, Stella / López-Hernández, Felipe / Navas-Arboleda, Alejandro A / Cortés, Andrés J

    Frontiers in plant science

    2022  Volume 13, Page(s) 843099

    Abstract: Grafting induces precocity and maintains clonal integrity in fruit tree crops. However, the complex rootstock × scion interaction often precludes understanding how the tree phenotype is shaped, limiting the potential to select optimum rootstocks. ... ...

    Abstract Grafting induces precocity and maintains clonal integrity in fruit tree crops. However, the complex rootstock × scion interaction often precludes understanding how the tree phenotype is shaped, limiting the potential to select optimum rootstocks. Therefore, it is necessary to assess (1) how seedling progenies inherit trait variation from elite 'plus trees', and (2) whether such family superiority may be transferred after grafting to the clonal scion. To bridge this gap, we quantified additive genetic parameters (i.e., narrow sense heritability-
    Language English
    Publishing date 2022-05-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.843099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Towards a Treatment for Gulf War Illness: A Consensus Docking Approach.

    Jaundoo, Rajeev / Bohmann, Jonathan / Gutierrez, Gloria E / Klimas, Nancy / Broderick, Gordon / Craddock, Travis J A

    Military medicine

    2020  Volume 185, Issue Suppl 1, Page(s) 554–561

    Abstract: Introduction: Gulf War Illness (GWI) currently has no known cure and affects soldiers deployed during the Persian Gulf War. It is thought to originate from exposure to neurotoxicants combined with battlefield stress, and previous research indicates that ...

    Abstract Introduction: Gulf War Illness (GWI) currently has no known cure and affects soldiers deployed during the Persian Gulf War. It is thought to originate from exposure to neurotoxicants combined with battlefield stress, and previous research indicates that treatment first involves inhibition of interleukin-2 and tumor necrosis factor alpha, followed by the glucocorticoid receptor. However, the off-target effects of pharmaceuticals hinder development of a drug treatment therapy.
    Materials and methods: AutoDock 4.2, AutoDock Vina, and Schrodinger's Glide were used to perform consensus docking, a computational technique where pharmaceuticals are screened against targets using multiple scoring algorithms to obtain consistent binding affinities. FDA approved pharmaceuticals were docked against the above-mentioned immune and stress targets to determine a drug therapy for GWI. Additionally, the androgen and estrogen targets were screened to avoid pharmaceuticals with off-target interactions.
    Results: While suramin bound to both immune targets with high affinity, top binders of the hormonal and glucocorticoid targets were non-specific towards their respective proteins, possibly due to high structure similarity between these proteins.
    Conclusions: Development of a drug treatment therapy for GWI is threatened by the tight interplay between the immune and hormonal systems, often leading to drug interactions. Increasing knowledge of these interactions can lead to break-through therapies.
    MeSH term(s) Consensus ; Humans ; Lymphokines/therapeutic use ; Persian Gulf Syndrome/drug therapy ; Tumor Necrosis Factor Inhibitors/therapeutic use
    Chemical Substances Lymphokines ; Tumor Necrosis Factor Inhibitors ; interleukin 2 inhibitor
    Language English
    Publishing date 2020-02-19
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usz299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Un I Zs.546: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Book ; Online: Voces Femeninas de Hispanoamerica

    Bautista Gutiérrez, Gloria

    (Pitt Latin American Series)

    2014  

    Abstract: ... Voces Femeninas de Hispanoamerica ... presents in one volume a selection of the most representative and outstanding writing by Latin American women writers from the seventeenth century to the present.  Designed as a text for third and fourth-year ...

    Series title Pitt Latin American Series
    Abstract
    Voces Femeninas de Hispanoamerica presents in one volume a selection of the most representative and outstanding writing by Latin American women writers from the seventeenth century to the present.  Designed as a text for third and fourth-year students, the selections, writers' biographies, historical introduction, and appendixes are entirely in Spanish, with notes to help students with difficult words or passages.
    Language Spanish
    Size Online-Ressource
    Publisher University of Pittsburgh Press
    Publishing place s.l
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 1322046204 ; 9780822938774 ; 9780822980773 ; 9781322046204 ; 0822938774 ; 0822980770
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Article ; Online: Using a Consensus Docking Approach to Predict Adverse Drug Reactions in Combination Drug Therapies for Gulf War Illness.

    Jaundoo, Rajeev / Bohmann, Jonathan / Gutierrez, Gloria E / Klimas, Nancy / Broderick, Gordon / Craddock, Travis J A

    International journal of molecular sciences

    2018  Volume 19, Issue 11

    Abstract: Gulf War Illness (GWI) is a chronic multisymptom illness characterized by fatigue, musculoskeletal pain, and gastrointestinal and cognitive dysfunction believed to stem from chemical exposures during the 1990⁻1991 Persian Gulf War. There are currently no ...

    Abstract Gulf War Illness (GWI) is a chronic multisymptom illness characterized by fatigue, musculoskeletal pain, and gastrointestinal and cognitive dysfunction believed to stem from chemical exposures during the 1990⁻1991 Persian Gulf War. There are currently no treatments; however, previous studies have predicted a putative multi-intervention treatment composed of inhibiting Th1 immune cytokines followed by inhibition of the glucocorticoid receptor (GCR) to treat GWI. These predictions suggest the use of specific monoclonal antibodies or suramin to target interleukin-2 and tumor necrosis factor α , followed by mifepristone to inhibit the GCR. In addition to this putative treatment strategy, there exist a variety of medications that target GWI symptomatology. As pharmaceuticals are promiscuous molecules, binding to multiple sites beyond their intended targets, leading to off-target interactions, it is key to ensure that none of these medications interfere with the proposed treatment avenue. Here, we used the drug docking programs AutoDock 4.2, AutoDock Vina, and Schrödinger's Glide to assess the potential off-target immune and hormone interactions of 43 FDA-approved drugs commonly used to treat GWI symptoms in order to determine their putative polypharmacology and minimize adverse drug effects in a combined pharmaceutical treatment. Several of these FDA-approved drugs were predicted to be novel binders of immune and hormonal targets, suggesting caution for their use in the proposed GWI treatment strategy symptoms.
    MeSH term(s) Cognitive Dysfunction/complications ; Cognitive Dysfunction/drug therapy ; Cognitive Dysfunction/metabolism ; Drug-Related Side Effects and Adverse Reactions/etiology ; Drug-Related Side Effects and Adverse Reactions/metabolism ; Fatigue Syndrome, Chronic/complications ; Fatigue Syndrome, Chronic/drug therapy ; Fatigue Syndrome, Chronic/metabolism ; Gastrointestinal Diseases/complications ; Gastrointestinal Diseases/drug therapy ; Gastrointestinal Diseases/metabolism ; Gulf War ; Humans ; Molecular Docking Simulation ; Molecular Targeted Therapy/methods ; Musculoskeletal Pain/complications ; Musculoskeletal Pain/drug therapy ; Musculoskeletal Pain/metabolism ; Polypharmacology ; Software
    Language English
    Publishing date 2018-10-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms19113355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Plasmid-mediated

    Gallardo, Alejandro / Iglesias, María-Rocío / Ugarte-Ruiz, María / Hernández, Marta / Miguela-Villoldo, Pedro / Gutiérrez, Gloria / Rodríguez-Lázaro, David / Domínguez, Lucas / Quesada, Alberto

    Antimicrobial agents and chemotherapy

    2021  Volume 65, Issue 5

    Abstract: The use of colistin as a last resort antimicrobial is compromised by the emergence of resistant enterobacteria with acquired determinants ... ...

    Abstract The use of colistin as a last resort antimicrobial is compromised by the emergence of resistant enterobacteria with acquired determinants like
    Language English
    Publishing date 2021-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/AAC.00091-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 809: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Einzelsignatur: Show issues

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