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  1. Article: Revealing the Meaning of Cannabis Use as an Occupation: A Scoping Review.

    Guyonnet, Emma / Stewart, Katherine E / Davis, Jane A

    Substance abuse : research and treatment

    2023  Volume 17, Page(s) 11782218221150113

    Abstract: Background: Occupational science and occupational therapy typically perceive occupations as promoting health and well-being. However, this perspective overlooks the many occupations that are viewed as illegal, unhealthy, or risky, such as drug use. Due ... ...

    Abstract Background: Occupational science and occupational therapy typically perceive occupations as promoting health and well-being. However, this perspective overlooks the many occupations that are viewed as illegal, unhealthy, or risky, such as drug use. Due to its negative association with health, drug use is perceived as not holding significance or meaning in people's lives.
    Objective: This study explores how individuals perceive and describe the meaning of their cannabis use in the context of their lives, from an occupational perspective.
    Methods: A scoping review was conducted using Levac et al.' modifications to Arksey and O'Malley's framework. To examine the peer-reviewed literature, 7 databases were searched using terms related to cannabis and meaning. Descriptive statistics were used to describe the selected studies, and reflexive thematic analysis identified cross-study themes.
    Results: Fourteen studies were selected. Most studies have been published since 2008, with 5 published in the last 2 years. Four themes were identified across the studies: (a) preserving life; (b) navigating the routines of everyday life; (c) understanding the self, identity, and belonging; and (d) expanding the view of the world.
    Conclusions: Cannabis use was revealed in this study as a support for navigating occupational routines and enhancing occupational repertoires and engagement, feelings of belonging, and collective user identities. As such, substance abuse treatment practices, including those provided by occupational therapists, should recognize the potential significance of cannabis use within people's lives. Using a harm reduction approach, occupational therapists can acknowledge the ways in which clients use cannabis to manage their daily routines, while also focusing on supporting clients to reduce the ill-effects of cannabis. As individuals become more engaged in occupations that are significant in their lives, their need for and meaning of cannabis use may change leading to a possible reduction in its use and a shift in their identity construction.
    Language English
    Publishing date 2023-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1458030-5
    ISSN 1547-0164 ; 1178-2218 ; 0889-7077
    ISSN (online) 1547-0164
    ISSN 1178-2218 ; 0889-7077
    DOI 10.1177/11782218221150113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Vitamin D and Calcium Supplement Use and High-Risk Breast Cancer: A Case-Control Study among

    Guyonnet, Emma / Kim, Shana J / Pullella, Katherine / Zhang, Cindy X W / McCuaig, Jeanna M / Armel, Susan / Narod, Steven A / Kotsopoulos, Joanne

    Cancers

    2023  Volume 15, Issue 10

    Abstract: The role of vitamin D and calcium use in the development of breast cancer among women in the general population is not clear. Furthermore, whether vitamin D and calcium supplement use are associated with breast cancer in high-risk populations has not ... ...

    Abstract The role of vitamin D and calcium use in the development of breast cancer among women in the general population is not clear. Furthermore, whether vitamin D and calcium supplement use are associated with breast cancer in high-risk populations has not been evaluated. Thus, we evaluated the association between vitamin D and/or calcium supplement use and breast cancer among women with a pathogenic variant (mutation) in
    Language English
    Publishing date 2023-05-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15102790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Physical Activity During Adolescence and Early-adulthood and Ovarian Cancer Among Women with a BRCA1 or BRCA2 Mutation.

    Guyonnet, Emma / Kim, Shana J / Xia, Yue Yin / Giannakeas, Vasily / Lubinski, Jan / Randall Armel, Susan / Eisen, Andrea / Bordeleau, Louise / Eng, Charis / Olopade, Olufunmilayo I / Tung, Nadine / Foulkes, William D / Couch, Fergus J / Aeilts, Amber M / Narod, Steven A / Kotsopoulos, Joanne

    Cancer research communications

    2023  Volume 3, Issue 11, Page(s) 2420–2429

    Abstract: In the general population, physical activity has been associated with a lower risk of several cancers; however, the evidence for ovarian cancer is not clear. It is suggested that early-life physical activity may differentially impact risk. Whether this ... ...

    Abstract In the general population, physical activity has been associated with a lower risk of several cancers; however, the evidence for ovarian cancer is not clear. It is suggested that early-life physical activity may differentially impact risk. Whether this is true among women at high risk due to a pathogenic variant (mutation) in the BRCA1 or BRCA2 genes has not been evaluated. Thus, we performed a matched case-control study to evaluate the association between adolescent and early-adulthood physical activity and ovarian cancer. BRCA mutation carriers who completed a research questionnaire on various exposures and incident disease and with data available on physical activity were eligible for inclusion. Self-reported activity at ages 12-13, 14-17, 18-22, 23-29, and 30-34 was used to calculate the average metabolic equivalent of task (MET)-hours/week for moderate, vigorous, and total physical activity during adolescence (ages 12-17) and early-adulthood (ages 18-34). Conditional logistic regression was used to estimate the OR and 95% confidence intervals (CI) of invasive ovarian cancer associated with physical activity. This study included 215 matched pairs (mean age = 57.3). There was no association between total physical activity during adolescence (ORhigh vs. low = 0.91; 95% CI: 0.61-1.36; Ptrend = 0.85), early-adulthood (ORhigh vs. low = 0.78; 95% CI: 0.51-1.20; Ptrend = 0.38) and overall (ORhigh vs. low = 0.81; 95% CI: 0.54-1.23; Ptrend = 0.56) and ovarian cancer. Findings were similar for moderate (Ptrend ≥ 0.25) and vigorous (Ptrend ≥ 0.57) activity. These findings do not provide evidence for an association between early-life physical activity and BRCA-ovarian cancer; however, physical activity should continue to be encouraged to promote overall health.
    Significance: In this matched case-control study, we observed no association between physical activity during adolescence or early-adulthood and subsequent risk of ovarian cancer. These findings do not provide evidence for an association between early-life physical activity and BRCA-ovarian cancer; however, being active remains important to promote overall health and well-being.
    MeSH term(s) Adolescent ; Humans ; Female ; Adult ; Middle Aged ; Case-Control Studies ; Ovarian Neoplasms/epidemiology ; Genes, BRCA2 ; Mutation ; Exercise ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics
    Chemical Substances BRCA1 protein, human ; BRCA1 Protein ; BRCA2 protein, human ; BRCA2 Protein
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2767-9764
    ISSN (online) 2767-9764
    DOI 10.1158/2767-9764.CRC-23-0223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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