LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Guzmán, María Camila"
  2. AU="Tom Van Den Bogaert"
  3. AU="Di Gioia, Mariacarla"
  4. AU=Hassan Omar F
  5. AU="Rose, Dale"
  6. AU="Baba, Satoshi"
  7. AU=Orienti Isabella
  8. AU="Ragasa, Catherine"
  9. AU="Sadrzadeh, S M Hossein"
  10. AU=Celedon Vera
  11. AU="Ravins Dohare"
  12. AU="Köcher, Thomas"
  13. AU="Iyengar, Sudha K"
  14. AU="Dimitroulis, Ioannis"
  15. AU="García Sandoval, Blanca"
  16. AU="Yuchio Yanagawa"
  17. AU="Ben Warne"
  18. AU="Freitas, Bruna Andrade Santos"
  19. AU="Behar, Raquel"
  20. AU="Hakimi, Mathew"
  21. AU="Voigt, C"
  22. AU="Harenberg, Job"
  23. AU="Bradfield, Owen"
  24. AU=Parmegiani Lodovico
  25. AU=Nasmyth Kim AU=Nasmyth Kim
  26. AU=Krumm Brian AU=Krumm Brian
  27. AU="Isojima, Tsuyoshi"
  28. AU="Rioufol, Gilles"
  29. AU="Hiesmayr, B. C."
  30. AU="Qudrat-Ullah, Hassan"
  31. AU=Kim Ginah Lee
  32. AU="Jeannin, Anne-Caroline"

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: Caracterización de fenotipos de asma en niños del trópico.

    Guzmán, María Camila / de Vivero, María / Gil, Isabel / Marrugo, Victoria / Mercado, Dilia / Zakzuk, Josefina / Puerta, Leonardo / Acevedo, Nathalie / Caraballo, Luis

    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

    2024  Volume 71, Issue 1, Page(s) 74

    Abstract: Objective: Determine the main asthma phenotypes in a population of asthmatic children in Cartagena, Colombia.: Methods: 107 children (7 to 17 years old) with a previous diagnosis of asthma were recruited. Biomarkers of T2 inflammation were evaluated ... ...

    Title translation Characterization of asthma phenotypes in children of the tropics.
    Abstract Objective: Determine the main asthma phenotypes in a population of asthmatic children in Cartagena, Colombia.
    Methods: 107 children (7 to 17 years old) with a previous diagnosis of asthma were recruited. Biomarkers of T2 inflammation were evaluated by measuring FeNO, eosinophil count in peripheral blood by hemocytometry, and determination of specific IgE to mite allergens by ELISA. The study was approved by the ethics committee of the University of Cartagena (SGR, Grant BPIN2020000100405).
    Results: The average age of patients was 10,9 years. 19,6% of the children did not show elevation of any of the T2 inflammation biomarkers evaluated (FeNO<20ppb, eos<300/ul, negative specific IgE), so they were considered patients with non-allergic asthma (non-T2). 71,9% of all patients were sensitized to at least one allergen, this phenotype was considered allergic asthma. 30,8% of the patients presented the three elevated biomarkers (FeNO>20ppb + eos >300/ul + positive specific IgE), this phenotype was classified as high T2 allergic asthma. A moderate correlation (Spearman rho=0,44, p<0,0001) was found between FeNO values and eosinophil counts.
    Conclusion: In this study, the following phenotypes were found: allergic asthma, high T2 asthma, and non-allergic asthma. Most patients presented a type 2 inflammatory phenotype with allergic sensitization. In addition to the measurement of specific IgE, the use of FeNO and eosinophil count in peripheral blood help to accurately determine those patients with high T2 asthma phenotypes.
    MeSH term(s) Humans ; Asthma/blood ; Child ; Phenotype ; Adolescent ; Male ; Female ; Immunoglobulin E/blood ; Eosinophils ; Tropical Climate ; Biomarkers/blood ; Colombia ; Leukocyte Count
    Chemical Substances Immunoglobulin E (37341-29-0) ; Biomarkers
    Language Spanish
    Publishing date 2024-02-01
    Publishing country Mexico
    Document type English Abstract ; Journal Article
    ZDB-ID 639125-4
    ISSN 2448-9190 ; 0002-5151
    ISSN (online) 2448-9190
    ISSN 0002-5151
    DOI 10.29262/ram.v71i1.1362
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Determinación de poblaciones circulantes en sangre periférica de linfocitos T, reguladores CD4

    Barrios-Angulo, Carlos E / de Vivero, María Mónica / Reina-Rivero, Randy / Guzmán, María Camila / Caballero, Miguel Ángel / Acevedo, Nathalie

    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

    2024  Volume 71, Issue 1, Page(s) 73

    Abstract: Objective: To carry out a preliminary analysis on the Treg lymphocyte counts present in the peripheral blood of allergic asthmatic children from the city of Cartagena, Colombia, compared to healthy controls.: Methods: We compared cytometry counts of ... ...

    Title translation Circulating populations of CD4+ CD25+ CD127- regulatory t lymphocytes in peripheral blood of allergic asthmatic children.
    Abstract Objective: To carry out a preliminary analysis on the Treg lymphocyte counts present in the peripheral blood of allergic asthmatic children from the city of Cartagena, Colombia, compared to healthy controls.
    Methods: We compared cytometry counts of ten asthmatic patients (age 7-16 years) and seven healthy controls (6-12 years), recruited in the city of Cartagena. Peripheral blood samples were stained using Cytek's 14-color cFluor Immunoprofiling kit (Cytek
    Results: The frequency of CD3+, CD4+, CD25+, CD127- Tregs was 11% of all CD4+ T cells, with a range of minimum 8,1% and maximum 17,7%. There was no significant difference in the proportion of Tregs between allergic asthmatic patients and healthy controls (P = 0,2).
    Conclusions: With this preliminary sample size, no significant differences were found in the Treg lymphocyte population between allergic asthmatic patients and healthy controls. The 14-color multiplexed panel is a useful tool not only to count CD3+ and CD4+ populations, but also to obtain the percentage of regulatory T cells using cell surface markers.
    MeSH term(s) Adolescent ; Child ; Female ; Humans ; Male ; Asthma/blood ; Asthma/immunology ; CD4 Antigens/analysis ; CD4 Antigens/blood ; Interleukin-2 Receptor alpha Subunit/blood ; Interleukin-2 Receptor alpha Subunit/analysis ; Interleukin-7 Receptor alpha Subunit/analysis ; Interleukin-7 Receptor alpha Subunit/blood ; Lymphocyte Count ; T-Lymphocytes, Regulatory/immunology ; CD4-Positive T-Lymphocytes/immunology
    Chemical Substances CD4 Antigens ; Interleukin-2 Receptor alpha Subunit ; Interleukin-7 Receptor alpha Subunit
    Language Spanish
    Publishing date 2024-02-01
    Publishing country Mexico
    Document type English Abstract ; Journal Article
    ZDB-ID 639125-4
    ISSN 2448-9190 ; 0002-5151
    ISSN (online) 2448-9190
    ISSN 0002-5151
    DOI 10.29262/ram.v71i1.1363
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top