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  1. Article: Analysis of Pharmaceutical Companies' Social Media Activity during the COVID-19 Pandemic and Its Impact on the Public.

    Gyftopoulos, Sotirios / Drosatos, George / Fico, Giuseppe / Pecchia, Leandro / Kaldoudi, Eleni

    Behavioral sciences (Basel, Switzerland)

    2024  Volume 14, Issue 2

    Abstract: The COVID-19 pandemic, a period of great turmoil, was coupled with the emergence of an "infodemic", a state when the public was bombarded with vast amounts of unverified information from dubious sources that led to a chaotic information landscape. The ... ...

    Abstract The COVID-19 pandemic, a period of great turmoil, was coupled with the emergence of an "infodemic", a state when the public was bombarded with vast amounts of unverified information from dubious sources that led to a chaotic information landscape. The excessive flow of messages to citizens, combined with the justified fear and uncertainty imposed by the unknown virus, cast a shadow on the credibility of even well-intentioned sources and affected the emotional state of the public. Several studies highlighted the mental toll this environment took on citizens by analyzing their discourse on online social networks (OSNs). In this study, we focus on the activity of prominent pharmaceutical companies on Twitter, currently known as X, as well as the public's response during the COVID-19 pandemic. Communication between companies and users is examined and compared in two discrete channels, the COVID-19 and the non-COVID-19 channel, based on the content of the posts circulated in them in the period between March 2020 and September 2022, while the emotional profile of the content is outlined through a state-of-the-art emotion analysis model. Our findings indicate significantly increased activity in the COVID-19 channel compared to the non-COVID-19 channel while the predominant emotion in both channels is joy. However, the COVID-19 channel exhibited an upward trend in the circulation of fear by the public. The quotes and replies produced by the users, with a stark presence of negative charge and diffusion indicators, reveal the public's preference for promoting tweets conveying an emotional charge, such as fear, surprise, and joy. The findings of this research study can inform the development of communication strategies based on emotion-aware messages in future crises.
    Language English
    Publishing date 2024-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651997-5
    ISSN 2076-328X
    ISSN 2076-328X
    DOI 10.3390/bs14020128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Psoriasis is associated with risk of obstructive sleep apnea independently from metabolic parameters and other comorbidities: a large hospital-based case-control study.

    Papadavid, Evangelia / Dalamaga, Maria / Vlami, Katerina / Koumaki, Dimitra / Gyftopoulos, Sotirios / Christodoulatos, Gerasimos Socrates / Papiris, Spyridon / Rigopoulos, Dimitrios

    Sleep & breathing = Schlaf & Atmung

    2017  Volume 21, Issue 4, Page(s) 949–958

    Abstract: Purpose: Obstructive sleep apnea (OSA) represents a breathing disorder during sleep with significant health consequences. Few studies have examined the prevalence of OSA in psoriatic patients and whether OSA may be associated with psoriasis risk. We ... ...

    Abstract Purpose: Obstructive sleep apnea (OSA) represents a breathing disorder during sleep with significant health consequences. Few studies have examined the prevalence of OSA in psoriatic patients and whether OSA may be associated with psoriasis risk. We aimed to explore: (1) the inverse relationship, that is whether psoriasis might represent an independent predictor of OSA and its severity considering important predisposing factors and (2) the psoriatic phenotype related to severe OSA.
    Methods: In a large hospital-based case-control study, we examined a total of 253 patients with OSA and a control group of 104 subjects without OSA, who underwent full nocturnal polysomnography and dermatologic examination.
    Results: The prevalence of psoriasis was significantly greater in OSA patients than in controls (p = 0.03). Psoriasis was associated with OSA risk (p = 0.04) but not severity of OSA, sleepiness severity or sleep efficiency, independently from age, gender, anthropometric features, and significant comorbidities. The phenotype of a psoriatic patient suffering from severe OSA is not different from that of a patient with severe OSA and is not associated with psoriasis severity indexes. OSA psoriatic patients were not compliant with CPAP treatment in comparison with OSA patients without psoriasis.
    Conclusion: Psoriasis may represent an independent risk factor for OSA above and beyond significant comorbidities, anthropometric and metabolic parameters. Physicians should be aware of the bi-directional association of psoriasis and OSA. Managing psoriasis may be a potential target for preventing OSA as well as the potential cardiovascular mortality related to OSA and psoriasis.
    MeSH term(s) Case-Control Studies ; Comorbidity ; Female ; Humans ; Male ; Middle Aged ; Polysomnography ; Prevalence ; Psoriasis/epidemiology ; Risk Factors ; Sleep Apnea, Obstructive/epidemiology
    Language English
    Publishing date 2017-05-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1500381-4
    ISSN 1522-1709 ; 1520-9512
    ISSN (online) 1522-1709
    ISSN 1520-9512
    DOI 10.1007/s11325-017-1507-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5658: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Sleep disturbance symptoms and their associations with alexithymia, depression and anxiety

    Gyftopoulos Sotirios / Karkanias Athanasios / Moussas Georgios / Tselebis Athanasios / Diamandi Christina / Lagou Sofia / Dumitru Silvia / Spanopoulou Asimoula / Bratis Dionisios / Kosmas Epaminondas

    Annals of General Psychiatry, Vol 9, Iss Suppl 1, p S

    2010  Volume 163

    Keywords Psychiatry ; RC435-571 ; Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Psychiatry ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2010-04-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Sleep oxygen desaturation predicts survival in idiopathic pulmonary fibrosis.

    Kolilekas, Likurgos / Manali, Effrosyni / Vlami, Katerina A / Lyberopoulos, Panagiotis / Triantafillidou, Christina / Kagouridis, Konstantinos / Baou, Katerina / Gyftopoulos, Sotirios / Vougas, Konstantinos N / Karakatsani, Anna / Alchanatis, Manos / Papiris, Spyros

    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    2013  Volume 9, Issue 6, Page(s) 593–601

    Abstract: Background: Recent studies suggest poor sleep quality in patients with idiopathic pulmonary fibrosis (IPF). However, so far, the impact of IPF-related sleep breathing disorders (SBDs) on survival has not been extensively studied.: Methods: In a ... ...

    Abstract Background: Recent studies suggest poor sleep quality in patients with idiopathic pulmonary fibrosis (IPF). However, so far, the impact of IPF-related sleep breathing disorders (SBDs) on survival has not been extensively studied.
    Methods: In a cohort of 31 (24 males) treatment-naïve, newly diagnosed consecutive IPF patients, we prospectively investigated the relationship of SBD parameters such as apnea-hypopnea index (AHI), maximal difference in oxygen saturation between wakefulness and sleep (maxdiff SpO2), and lowest sleep oxygen saturation (lowest SpO2) with clinical (survival, dyspnea, daytime sleepiness), pulmonary function, submaximal (6-min walk test [6MWT]) and maximal exercise variables (cardiopulmonary exercise test [CPET]), and right ventricular systolic pressure (RVSP).
    Results: Sleep oxygen desaturation exceeded significantly that of maximal exercise (p < 0.001). Maxdiff SpO2 was inversely related to survival, DLCO%, and SpO2 after 6MWT, and directly with dyspnea, AHI, and RVSP. The lowest SpO2 was directly related to survival and to functional (TLC%, DLCO%) as well as submaximal and maximal exercise variables (6MWT distance, SpO2 after 6MWT, peak oxygen consumption/kg, SpO2 at peak exercise), while an inverse association with dyspnea score, AHI, and RVSP was observed.
    Conclusions: Our findings provide evidence that intermittent sleep oxygen desaturation significantly exceeds that of maximal exercise and is associated with survival in IPF patients. Furthermore, they imply the existence of a link between lung damage and apnea events resulting to the induction and severity of intermittent sleep oxygen desaturation that aggravate pulmonary arterial hypertension and influence IPF survival.
    MeSH term(s) Aged ; Comorbidity ; Disease Progression ; Dyspnea/epidemiology ; Exercise Tolerance ; Female ; Greece/epidemiology ; Humans ; Idiopathic Pulmonary Fibrosis/epidemiology ; Idiopathic Pulmonary Fibrosis/mortality ; Kaplan-Meier Estimate ; Likelihood Functions ; Male ; Oxygen/metabolism ; Prospective Studies ; Sleep Apnea Syndromes/epidemiology ; Survival Rate
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2013-06-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2397213-0
    ISSN 1550-9397 ; 1550-9389
    ISSN (online) 1550-9397
    ISSN 1550-9389
    DOI 10.5664/jcsm.2758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6590: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: The Role of Cardiopulmonary Exercise Test in IPF Prognosis.

    Triantafillidou, Christina / Manali, Effrosyni / Lyberopoulos, Panagiotis / Kolilekas, Likourgos / Kagouridis, Konstantinos / Gyftopoulos, Sotirios / Vougas, Konstantinos / Kotanidou, Anastasia / Alchanatis, Manos / Karakatsani, Anna / Papiris, Spyros A

    Pulmonary medicine

    2013  Volume 2013, Page(s) 514817

    Abstract: Background. In IPF, defects in lung mechanics and gas exchange manifest with exercise limitation due to dyspnea, the most prominent and disabling symptom. Aim. To evaluate the role of exercise testing through the 6MWT (6-minute walk test) and CPET ( ... ...

    Abstract Background. In IPF, defects in lung mechanics and gas exchange manifest with exercise limitation due to dyspnea, the most prominent and disabling symptom. Aim. To evaluate the role of exercise testing through the 6MWT (6-minute walk test) and CPET (cardiopulmonary exercise testing) in the survival of patients with IPF. Methods. This is a prospective, observational study evaluating in 25 patients the relationship between exercise variables through both the 6MWT and CPET and survival. Results. By the end of the observational period 17 patients were alive (33% mortality). Observation ranged from 9 to 64 months. VE/VCO2 slope (slope of relation between minute ventilation and CO2 production), VO2 peak/kg (peak oxygen consumption/kg), VE/VCO2 ratio at anaerobic threshold, 6MWT distance, desaturation, and DLCO% were significant predictors of survival while VE/VCO2 slope and VO2 peak/kg had the strongest correlation with outcome. The optimal model for mortality risk estimation was VO2 peak/kg + DLCO% combined. Furthermore, VE/VCO2 slope and VO2 peak/kg were correlated with distance and desaturation during the 6MWT. Conclusion. The integration of oxygen consumption and diffusing capacity proved to be a reliable predictor of survival because both variables reflect major underlying physiologic determinants of exercise limitation.
    Language English
    Publishing date 2013-10-31
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2603580-7
    ISSN 2090-1844 ; 2090-1836
    ISSN (online) 2090-1844
    ISSN 2090-1836
    DOI 10.1155/2013/514817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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