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Article ; Online: Skin infections in pregnancy.

Müllegger, Robert R / Häring, Nina S / Glatz, Martin

Clinics in dermatology

2016  Volume 34, Issue 3, Page(s) 368–377

Abstract: A wide array of infectious diseases can occur in pregnancy. Their acquisition, clinical presentation, and course during gestation may be altered due to an impairment of the maternal cellular immunity. Some infectious diseases can lead to serious ... ...

Abstract A wide array of infectious diseases can occur in pregnancy. Their acquisition, clinical presentation, and course during gestation may be altered due to an impairment of the maternal cellular immunity. Some infectious diseases can lead to serious consequences for the mother or the offspring, including congenital malformations. This review describes in detail the clinical presentation, course, management, and associated maternal and fetal risks of selected viral (varicella-zoster virus infections, condylomata acuminata), fungal (candida vulvovaginitis), bacterial (Lyme borreliosis), and parasitic (scabies) infections. The treatment options are critically reviewed. First-line therapies include acyclovir and varicella-zoster virus immunoglobulin for varicella-zoster virus infections, surgical modalities for genital warts, topical clotrimazole and oral fluconazole for Candida vulvovaginitis, amoxicillin and cefuroxime for Lyme borreliosis, and permethrin for scabies. A synopsis of maternal and fetal risks of other important infections is also included.
MeSH term(s) Candidiasis, Vulvovaginal/drug therapy ; Candidiasis, Vulvovaginal/transmission ; Cesarean Section ; Chickenpox/complications ; Chickenpox/congenital ; Chickenpox/drug therapy ; Chickenpox/transmission ; Condylomata Acuminata/therapy ; Female ; Fetal Diseases/microbiology ; Herpes Zoster/drug therapy ; Herpes Zoster/transmission ; Humans ; Infectious Disease Transmission, Vertical/prevention & control ; Lyme Disease/complications ; Lyme Disease/drug therapy ; Pregnancy ; Pregnancy Complications, Infectious/microbiology ; Pregnancy Complications, Infectious/therapy ; Pregnancy Complications, Parasitic/drug therapy ; Pregnancy Outcome ; Scabies/drug therapy ; Skin Diseases, Infectious/microbiology ; Skin Diseases, Infectious/therapy ; Skin Diseases, Infectious/transmission
Language English
Publishing date 2016-05
Publishing country United States
Document type Journal Article ; Review
ZDB-ID 1064149-x
ISSN 1879-1131 ; 0738-081X
ISSN (online) 1879-1131
ISSN 0738-081X
DOI 10.1016/j.clindermatol.2016.02.009
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