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  1. Article ; Online: Protective actions of a luminally acting 5-HT

    Hurd, Molly / Haag, Melody M / Kwasnik, Matthew J / Wykosky, Jill / Lavoie, Brigitte / Mawe, Gary M

    Neurogastroenterology and motility

    2023  Volume 35, Issue 11, Page(s) e14673

    Abstract: Background: 5-hydroxytryptamine 4 receptors (5-HT: Methods: The dextran sodium sulfate (DSS), trinitrobenzene sulfonic acid (TNBS), and interleukin 10 knockout (IL-10KO) models of colitis were used to test the protective effects of the luminally ... ...

    Abstract Background: 5-hydroxytryptamine 4 receptors (5-HT
    Methods: The dextran sodium sulfate (DSS), trinitrobenzene sulfonic acid (TNBS), and interleukin 10 knockout (IL-10KO) models of colitis were used to test the protective effects of the luminally acting 5-HT
    Key results: Daily enema of 5HT4-LA1 attenuated the development of, and accelerated recovery from, active colitis. Enema administration of 5HT4-LA1 did not attenuate the development of colitis in 5-HT
    Conclusions and inferences: Luminally restricted 5-HT
    MeSH term(s) Humans ; Mice ; Animals ; Serotonin ; Caco-2 Cells ; Colitis/chemically induced ; Colitis/drug therapy ; Colitis/pathology ; Mice, Knockout ; Water
    Chemical Substances Serotonin (333DO1RDJY) ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.14673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2979: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Prokinetic actions of luminally acting 5-HT

    Konen, John R / Haag, Melody M / Guseva, Daria / Hurd, Molly / Linton, Alisha A / Lavoie, Brigitte / Kerrigan, Colleen B / Joyce, Emily / Bischoff, Stephan C / Swann, Steve / Griffin, Luana / Matsukawa, Jun / Falk, Matthew D / Gibson, Tony S / Hennig, Grant W / Wykosky, Jill / Mawe, Gary M

    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

    2020  Volume 33, Issue 4, Page(s) e14026

    Abstract: Background: 5-HT: Methods: Non-absorbed 5-HT: Key results: Pharmacological screening demonstrated selectivity and potency of test agonists for 5-HT: Conclusions and inferences: These findings demonstrated that stimulation of epithelial 5- ... ...

    Abstract Background: 5-HT
    Methods: Non-absorbed 5-HT
    Key results: Pharmacological screening demonstrated selectivity and potency of test agonists for 5-HT
    Conclusions and inferences: These findings demonstrated that stimulation of epithelial 5-HT
    MeSH term(s) Animals ; CHO Cells ; Colon/drug effects ; Colon/physiology ; Constipation/drug therapy ; Constipation/physiopathology ; Cricetinae ; Cricetulus ; Gastrointestinal Motility/drug effects ; Gastrointestinal Motility/physiology ; Humans ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Receptors, Serotonin, 5-HT4/physiology ; Serotonin 5-HT4 Receptor Agonists/pharmacology ; Serotonin 5-HT4 Receptor Agonists/therapeutic use
    Chemical Substances Serotonin 5-HT4 Receptor Agonists ; Receptors, Serotonin, 5-HT4 (158165-40-3)
    Language English
    Publishing date 2020-11-12
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.14026
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2979: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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