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  1. AU="Haddadin, Fadi"
  2. AU="McClean, Marisha"
  3. AU="Ackerman, Kate G"

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  1. Article ; Online: GLP-1 receptor agonists: A novel pharmacotherapy for binge eating (Binge eating disorder and bulimia nervosa)? A systematic review.

    Aoun, Laurence / Almardini, Shaza / Saliba, Fares / Haddadin, Fadi / Mourad, Omar / Jdaidani, Jennifer / Morcos, Zeina / Al Saidi, Ibrahim / Bou Sanayeh, Elie / Saliba, Saliba / Almardini, Michel / Zaidan, Julie

    Journal of clinical & translational endocrinology

    2024  Volume 35, Page(s) 100333

    Abstract: Objective: Systematically review evidence on using GLP-1RAs for reducing BEB in BED and BN.: Methods: Comprehensive literature search (PubMed and Google Scholar) conducted for studies evaluating GLP-1Ras for BEB. Extracted data on study ... ...

    Abstract Objective: Systematically review evidence on using GLP-1RAs for reducing BEB in BED and BN.
    Methods: Comprehensive literature search (PubMed and Google Scholar) conducted for studies evaluating GLP-1Ras for BEB. Extracted data on study characteristics, efficacy, and safety.
    Results: Studies show that GLP-1RAs (liraglutide and dulaglutide) reduce BE frequency and comorbidities in addition to favorable psychiatric side effect profile compared to current options. However, large-scale, blinded placebo-controlled trials are lacking.
    Conclusion: Early findings suggest promising effects of GLP-1RAs on BEB. However, rigorous clinical trials are needed to firmly establish efficacy, dosing, safety, and comparative effectiveness before considering GLP-1RAs a viable novel approach.
    Language English
    Publishing date 2024-02-29
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2834222-7
    ISSN 2214-6237 ; 2214-6237
    ISSN (online) 2214-6237
    ISSN 2214-6237
    DOI 10.1016/j.jcte.2024.100333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Waterpipe Smoking among Bladder Cancer Patients: A Cross-Sectional Study of Lebanese and Jordanian Populations.

    Jabra, Elio / Al-Omari, Amal / Haddadin, Fadi / Alam, Walid / Ammar, Khawlah / Charafeddine, Maya / Alrawashdeh, Mohammad / Kasasbeh, Nour / Habis, Charbel / Mukherji, Deborah / Temraz, Sally / Shamseddine, Ali

    Journal of smoking cessation

    2021  Volume 2021, Page(s) 6615832

    Abstract: Background: Bladder cancer (BC) is the second most reported cancer in Lebanon and the fifth in Jordan. Its risk factors are mainly smoking and occupational exposure to aromatic amines. In these countries where smoking and bladder cancer are highly ... ...

    Abstract Background: Bladder cancer (BC) is the second most reported cancer in Lebanon and the fifth in Jordan. Its risk factors are mainly smoking and occupational exposure to aromatic amines. In these countries where smoking and bladder cancer are highly prevalent, the role of waterpipe smoking (WPS) in bladder cancer is less investigated. We aim to compare two sets of patients between Lebanon and Jordan, focusing on their smoking habits, WP use, occupational exposure, and the grade/invasiveness of their bladder cancer.
    Methods: This is a cross-sectional study that compares the smoking culture between two sets of populations with bladder cancer, from two different countries. We recruited 274 bladder cancer patients over the 18 years of age at the American University of Beirut Medical Center (AUBMC), and 158 bladder cancer patients over the age of 18 years at the King Hussein Cancer Center (KHCC).
    Results: 7.7% of Lebanese patients had significantly more positive family history of bladder cancer compared to 13.9% of Jordanian patients (
    Conclusions: Bladder cancer incidence is on the rise in both Jordan and Lebanon along with different smoking types. It is necessary to impose prevention policies to prevent and control the high smoking prevalence. Bladder cancer invasiveness is higher in Jordan compared to universal data.
    Language English
    Publishing date 2021-04-19
    Publishing country England
    Document type Journal Article
    ISSN 1834-2612
    ISSN (online) 1834-2612
    DOI 10.1155/2021/6615832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online ; Research data: (with research data) Characterizing the interaction between physicians, pharmacists and pharmaceutical representatives in a middle-income country: A qualitative study.

    Hajjar, Rima / Bassatne, Aya / Cheaito, Mohamad Ali / Naser El Dine, Rabie / Traboulsy, Sarah / Haddadin, Fadi / Honein-AbouHaidar, Gladys / Akl, Elie A

    PloS one

    2017  Volume 12, Issue 9, Page(s) e0184662

    Abstract: Background: Studies around the world have shown that interactions between pharmaceutical companies, pharmacists and physicians have a great influence on prescribing and drug dispensing practices. In middle-income countries, the nature and extent of ... ...

    Abstract Background: Studies around the world have shown that interactions between pharmaceutical companies, pharmacists and physicians have a great influence on prescribing and drug dispensing practices. In middle-income countries, the nature and extent of these interactions have not been well researched. Our objectives were to qualitatively explore the nature of the interactions between pharmaceutical companies, physicians and pharmacists, their impact on drug prescription and dispensing practices in Lebanon.
    Methods and findings: We used grounded theory approach as well as the known sponsor, purposive, and snowballing sampling strategies to identify interviewees from the three respective groups: physicians, pharmacists, and pharmaceutical representatives. We conducted semi-structured and analyzed transcripts thematically. This study encompassed 6 pharmaceutical representatives, 13 physicians and 13 pharmacists. The following themes emerged: purpose and driver for the interactions, nature of the interactions, incentives, impact on prescription practices, ethical considerations, and suggestions for managing the interactions. The main purposes for the interaction were educational, promotional, and monitoring prescription practices and dispensing, while the main drivers for these interactions were market potential and neighborhood socio-economic status. Physicians, pharmacists and pharmaceutical representatives who engage in these interactions benefit from a variety of incentives, some of which were characterized as unethical. It appears that pharmaceutical companies give prominence to selected physicians within their communities. Although members of the three interviewed groups refer to some of the interactions as being problematic, they described a culture of acceptance of gift giving. We developed a framework that depicts the prevailing politico-cultural environment, the interactions between the three professional groups, and their impact on drug prescription. Underreporting is the main limitation of this study.
    Conclusion: Interactions between physicians, pharmacists and pharmaceutical representatives are frequent. Although these interactions can be beneficial, they still have a substantial effect on drug prescription and dispensing practices. Hence, the need for new policies that regulate these interactions and penalize any misconduct.
    MeSH term(s) Drug Prescriptions/standards ; Female ; Humans ; Interprofessional Relations ; Lebanon ; Male ; Marketing of Health Services/standards ; Pharmacists/psychology ; Physicians/psychology ; Socioeconomic Factors
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0184662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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