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  1. Book: The Mayo Clinic Cardiac Catheterization Laboratory

    Holmes Jr., David R. / Frye, Robert L. / Ritman, Erik L. / Hagler, Donald J / Munger, Thomas M. / Friedman, Paul A.

    History, Research, and Innovations

    2021  

    Author's details Dr. David R. Holmes, Jr - Dr. Holmes is currently a Professor of Medicine at the Mayo Clinic College of Medicine and a consultant in the Department of Cardiovascular Medicine at Mayo Clinic in Rochester, Minnesota. Dr. Holmes has also been named the Edward W. and Betty Knight Scripps Professor in Cardiovascular Medicine in Honor of Dr. George M. Gura, Jr. He was the Director of the Cardiac Catheterization Laboratory from 1984-2003. He was awarded an Honorary Fellowship of the Royal College of Physicians in Ireland in November 2011. He has received the Distinguished Scientist Award (Clinical Domain) from the American College of Cardiology and the Research Career Achievement Award from the Mayo Graduate School of Medicine. He is a Past President of the American College of Cardiology (ACC) as well as the Society for Cardiac Angiography and Interventions (SCAI). He has received the Herrick Award from the American Heart Association. Dr. Holmes continues to lecture both nationally and
    Keywords Mayo Clinic Catheterization Laboratory ; Cardiovascular Disease ; E.H. Wood ; Stroke prevention ; First AV nodal ablation ; First catheter ablation for ventricular tachycardia ; First Pacemaker ; Electronic and imaging methodology ; Computed Tomography ; congenital heart disease ; Coronary Heart Disease ; hemodynamics ; Indocyanine Green dye ; Cardioversion ; Video densitometry technique ; Right and Left heart catheterization ; Satellite transmission ; New innovation treatment strategies ; The first clinical CT (the Dynamic Spatial Reconstructor) ; Stent Implantation ; Cardiovascular disease ; Congenital heart disease ; Coronary heart disease ; Hemodynamics ; Stent implantation
    Language English
    Size 396 p.
    Edition 1
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_12
    Format 160 x 241 x 22
    ISBN 9783030793289 ; 3030793281
    Database PDA

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  2. Article ; Online: Not to worry (most of the time).

    Hagler, Donald J

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2020  Volume 95, Issue 5, Page(s) 937–938

    Abstract: Most (87.6%) of residual atrial L-R shunts after Gore Cardioform septal occluder implant disappear by 12 months. Residual leaks at implantation were more common in larger defects with smaller retro-aortic rims, and multiple fenestrations. While most ... ...

    Abstract Most (87.6%) of residual atrial L-R shunts after Gore Cardioform septal occluder implant disappear by 12 months. Residual leaks at implantation were more common in larger defects with smaller retro-aortic rims, and multiple fenestrations. While most residual defects close in 12 months, we unfortunately do not yet have a clear idea why or which of the 13% do not close.
    MeSH term(s) Heart Septal Defects, Atrial ; Humans ; Prosthesis Design ; Septal Occluder Device ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2020-04-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28877
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  3. Article: Is MYBPC3 linked to bicuspid aortic valve?

    Niaz, Talha / Hagler, Donald J

    Translational pediatrics

    2021  Volume 10, Issue 2, Page(s) 223–224

    Language English
    Publishing date 2021-03-26
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2901309-4
    ISSN 2224-4344 ; 2224-4344 ; 2224-4336
    ISSN (online) 2224-4344
    ISSN 2224-4344 ; 2224-4336
    DOI 10.21037/tp-20-477
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  4. Article ; Online: The Lababidi Procedure: Is Neonatal Balloon Aortic Valvotomy Worth the Risk?

    Hagler, Donald J

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2017  Volume 89, Issue 2, Page(s) 296–297

    MeSH term(s) Aortic Valve Stenosis ; Cardiac Surgical Procedures ; Catheterization ; Humans ; Treatment Outcome
    Language English
    Publishing date 2017--01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.26923
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  5. Article ; Online: Catheterization in Adults With Congenital Heart Disease: A Primer for the Noncongenital Proceduralist.

    Miranda, William R / Aboulhosn, Jamil A / Hagler, Donald J

    JACC. Cardiovascular interventions

    2022  Volume 15, Issue 9, Page(s) 907–921

    Abstract: Currently in the United States, more than 1 million adults have congenital heart disease. Therefore, it will be inevitable for providers performing cardiac catheterization to be faced with adults with repaired congenital heart abnormalities. Moreover, a ... ...

    Abstract Currently in the United States, more than 1 million adults have congenital heart disease. Therefore, it will be inevitable for providers performing cardiac catheterization to be faced with adults with repaired congenital heart abnormalities. Moreover, a meticulous approach to every cardiac catheterization procedure is mandatory to avoid missing unrecognized congenital lesions presenting in adulthood. The authors provide a primer for cardiac catheterization procedures in adults with congenital heart disease, reviewing key procedural components: flow calculation, detection of shunts according to different lesions, and, when indicated, ventricular angiography and coronary angiography.
    MeSH term(s) Adult ; Cardiac Catheterization/methods ; Coronary Angiography ; Heart Defects, Congenital/diagnostic imaging ; Heart Defects, Congenital/therapy ; Humans ; Treatment Outcome ; United States
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2021.12.020
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  6. Article ; Online: Good news and bad news.

    Hagler, Donald J

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2016  Volume 88, Issue 3, Page(s) 444–445

    Abstract: Current delivery systems for the Sapien XT valve for the native pulmonary valve are unacceptable stiff and poorly design for implantation in the pulmonary outflow tract. This report details improvisation of the Melody Ensemble for easier pulmonary ... ...

    Abstract Current delivery systems for the Sapien XT valve for the native pulmonary valve are unacceptable stiff and poorly design for implantation in the pulmonary outflow tract. This report details improvisation of the Melody Ensemble for easier pulmonary outflow tract delivery of the Sapien XT valve. The unacceptable cost of the utilization of two delivery systems for valve implantation, requires industry development of an safe, effective delivery system appropriate for the pulmonary outflow tract.
    MeSH term(s) Cardiac Catheterization ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation ; Humans ; Prosthesis Design ; Treatment Outcome
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.26713
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  7. Article ; Online: Percutaneous paravalvular leak closure? Perhaps a glimmer of hope after a long course of marginal success.

    Hagler, Donald J

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2016  Volume 11, Issue 10, Page(s) 1095–1096

    MeSH term(s) Cardiac Catheterization ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation ; Humans ; Prosthesis Failure
    Language English
    Publishing date 2016-02
    Publishing country France
    Document type Comment ; Editorial
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJV11I10A222
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  8. Article: Is there a genetic basis to the different morphological subtypes of bicuspid aortic valve?

    Niaz, Talha / Hagler, Donald J

    Annals of translational medicine

    2019  Volume 6, Issue Suppl 2, Page(s) S117

    Language English
    Publishing date 2019-01-22
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2018.12.21
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  9. Article ; Online: Hemodynamics in Adults with Systemic Right Ventricles: Differences Between Congenitally Corrected and Complete Transposition of the Great Arteries.

    Miranda, William R / Jain, C Charles / Egbe, Alexander C / Reddy, Yogesh N / Dearani, Joseph A / Hagler, Donald J / Connolly, Heidi M

    Pediatric cardiology

    2024  

    Abstract: Despite their anatomical differences, congenitally corrected (ccTGA) and complete transposition of the great arteries (d-TGA) post-atrial switch are frequently studied together and managed similarly from a medical standpoint due to the shared systemic ... ...

    Abstract Despite their anatomical differences, congenitally corrected (ccTGA) and complete transposition of the great arteries (d-TGA) post-atrial switch are frequently studied together and managed similarly from a medical standpoint due to the shared systemic right ventricle (sRV). The aim was to assess differences in their underlying hemodynamics. The study is a retrospective review of 138 adults with ccTGA or d-TGA post-atrial switch undergoing cardiac catheterization at Mayo Clinic, MN between 2000 and 2021. ccTGA was categorized into isolated or complex ccTGA depending on concomitant ventricular septal defect and/or left ventricular outflow obstruction. There were 53 patients with d-TGA (91% post-Mustard procedure), 51 with complex and 34 with isolated ccTGA. Isolated ccTGA patients were older (51.8 ± 13.1 years) than those with d-TGA (37.5 ± 8.3 years) or complex ccTGA (40.8 ± 13.4 years). There were no differences in sRV or left ventricular size and function across groups. The ccTGA group more commonly had ≥ moderate tricuspid regurgitation than those with d-TGA; ≥ moderate mitral and ≥ moderate pulmonary regurgitation were most prevalent in complex ccTGA. There were no differences in sRV end-diastolic pressure (sRVEDP) or PAWP between groups. However, the ratio of PAWP:sRVEDP was higher in those with d-TGA compared to those with ccTGA. Cardiac index was higher in the d-TGA group than both groups of ccTGA patients with the latter showing higher indices of ventricular afterload. In conclusion, despite sharing a sRV, adults with d-TGA and ccTGA have substantial differences in hemodynamics and structural/valvular abnormalities. Further investigation regarding disease-specific responses to heart failure therapy in those with d-TGA and ccTGA is warranted.
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 800857-7
    ISSN 1432-1971 ; 0172-0643
    ISSN (online) 1432-1971
    ISSN 0172-0643
    DOI 10.1007/s00246-023-03381-w
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  10. Article ; Online: Elevated Pure Tone Thresholds Are Associated with Altered Microstructure in Cortical Areas Related to Auditory Processing and Attentional Allocation.

    McEvoy, Linda K / Bergstrom, Jaclyn / Hagler, Donald J / Wing, David / Reas, Emilie T

    Journal of Alzheimer's disease : JAD

    2023  Volume 96, Issue 3, Page(s) 1163–1172

    Abstract: Background: Hearing loss is associated with cognitive decline and increased risk for Alzheimer's disease, but the basis of this association is not understood.: Objective: To determine whether hearing impairment is associated with advanced brain aging ...

    Abstract Background: Hearing loss is associated with cognitive decline and increased risk for Alzheimer's disease, but the basis of this association is not understood.
    Objective: To determine whether hearing impairment is associated with advanced brain aging or altered microstructure in areas involved with auditory and cognitive processing.
    Methods: 130 participants, (mean 76.4±7.3 years; 65% women) of the Rancho Bernardo Study of Healthy Aging had a screening audiogram in 2003-2005 and brain magnetic resonance imaging in 2014-2016. Hearing ability was defined as the average pure tone threshold (PTA) at 500, 1000, 2000, and 4000 Hz in the better-hearing ear. Brain-predicted age difference (Brain-pad) was calculated as the difference between brain-predicted age based on a validated structural imaging biomarker of brain age, and chronological age. Regional diffusion metrics in temporal and frontal cortex regions were obtained from diffusion-weighted MRIs. Linear regression analyses adjusted for age, gender, education, and health-related measures.
    Results: PTAs were not associated with brain-PAD (β= 0.09; 95% CI: -0.084 to 0.243; p = 0.34). PTAs were associated with reduced restricted diffusion and increased free water diffusion primarily in right hemisphere temporal and frontal areas (restricted diffusion: βs = -0.21 to -0.30; 95% CIs from -0.48 to -0.02; ps < 0.03; free water: βs = 0.18 to 0.26; 95% CIs 0.01 to 0.438; ps < 0.04).
    Conclusions: Hearing impairment is not associated with advanced brain aging but is associated with differences in brain regions involved with auditory processing and attentional control. It is thus possible that increased dementia risk associated with hearing impairment arises, in part, from compensatory brain changes that may decrease resilience.
    MeSH term(s) Humans ; Female ; Male ; Auditory Perception ; Hearing ; Brain/pathology ; Hearing Loss ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-11-07
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1440127-7
    ISSN 1875-8908 ; 1387-2877
    ISSN (online) 1875-8908
    ISSN 1387-2877
    DOI 10.3233/JAD-230767
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