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  1. AU="Hahn, Rachel"
  2. AU="Malone, Candice L"

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  1. Article: CB

    Watkins, Joshua / Aradi, Petra / Hahn, Rachel / Katona, Istvan / Mackie, Ken / Makriyannis, Alexandros / Hohmann, Andrea G

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Recreational use of synthetic cannabinoid agonists (i.e., "Spice" compounds) that target the Cannabinoid Type 1 receptor ( ... ...

    Abstract Recreational use of synthetic cannabinoid agonists (i.e., "Spice" compounds) that target the Cannabinoid Type 1 receptor (CB
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.03.12.584260
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Health Versus Appearance Versus Body Competence: A Content Analysis Investigating Frames of Health Advice in Women's Health Magazines.

    Aubrey, Jennifer Stevens / Hahn, Rachel

    Journal of health communication

    2016  Volume 21, Issue 5, Page(s) 496–503

    Abstract: The present study investigated the extent to which women's health magazines advise readers to adopt healthy behaviors in order to look good (appearance frame), in order to feel good (health frame), or in order to perform better (body competence frame). A ...

    Abstract The present study investigated the extent to which women's health magazines advise readers to adopt healthy behaviors in order to look good (appearance frame), in order to feel good (health frame), or in order to perform better (body competence frame). A content analysis of 5 years of the 6 highest circulating U.S. women's health magazines revealed a higher frequency of health frames (32.6%) than appearance frames (24.8%) overall, but when beauty/health hybrid magazines (i.e., Shape and Self) were examined separately, appearance frames (32.8%) outnumbered health frames (26.5%). Compared to appearance and health frames, body competence frames were underrepresented (13.3% in the full sample). The visual sexual objectification of female models in women's health magazines was also investigated. Appearance-framed articles (43.2%) were significantly more likely to visually depict women with a high degree of skin exposure than health-framed articles (17.4%), and appearance-framed articles (34.8%) were more likely to focus on individual body parts than health-framed articles (21.3%). In addition, despite the magazines' editorial focus on health, the most frequent category of products advertised was appearance-enhancing products. Results are discussed in light of self-determination theory (Deci & Ryan, 1985) and objectification theory (Fredrickson & Roberts, 1997).
    MeSH term(s) Female ; Health Behavior ; Health Communication/methods ; Health Promotion ; Humans ; Periodicals as Topic/statistics & numerical data ; Physical Appearance, Body ; Women's Health
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1427988-5
    ISSN 1087-0415 ; 1081-0730
    ISSN (online) 1087-0415
    ISSN 1081-0730
    DOI 10.1080/10810730.2015.1103328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5899: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Effects of Cough Suppression Therapy on Voice Disorder Severity.

    LaTour, Donn / Crawley, Brianna / Krishna, Priya / Hahn, Rachel / Murry, Thomas

    The Laryngoscope

    2021  Volume 131, Issue 12, Page(s) 2747–2751

    Abstract: Objectives//hypothesis: To determine changes in voice severity when treating chronic cough refractory to medical treatment with cough suppression therapy (CST) in patients with chronic cough and voice complaints. Chronic cough has been reported to be ... ...

    Abstract Objectives//hypothesis: To determine changes in voice severity when treating chronic cough refractory to medical treatment with cough suppression therapy (CST) in patients with chronic cough and voice complaints. Chronic cough has been reported to be refractory to medical treatment and frequently co-occurs with voice disorders. The possible effects of CST on self-assessed changes in chronic cough and voice disorders have not been demonstrated.
    Study design: Retrospective analysis of the effects of cough suppression therapy (CST) on self-assessed changes in chronic cough and voice disorder severity in patients with both chronic cough and voice disorders.
    Methods: Forty-three adult patients with the primary complaint of chronic refractory cough underwent pre- and post-treatment diagnostic examinations, completed pre- and post-treatment Voice Handicap Index-10 (VHI-10) and Cough Severity Index assessments, and were treated by a licensed speech-language pathologist using CST. Twenty-seven subjects were assigned to the cough (C) group and 16 to the cough-voice (CV) group based on the severity of their VHI-10 scores.
    Results: Post-test analysis showed significant improvement in cough severity for both groups and significant improvement in voice severity for the CV group. The VHI-10 scores for the C group did not change significantly. The median number of treatment sessions was 3, with a range of 1-13 sessions. Correlation between changes in severity and number of treatment sessions was not found to be significant at the tested level.
    Conclusions: CST represents a unifying approach for treatment of patients with CRC and comorbid voice disorders. CST offered cross-over effects to the voice when subjects were treated for their primary complaint of chronic cough. This treatment of the primary complaint improves function in systems that share a common pathway.
    Level of evidence: 4 Laryngoscope, 131:2747-2751, 2021.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Breathing Exercises/methods ; Chronic Disease/therapy ; Cough/complications ; Cough/therapy ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Severity of Illness Index ; Treatment Outcome ; Voice Disorders/diagnosis ; Voice Disorders/etiology ; Voice Disorders/therapy ; Voice Quality ; Young Adult
    Language English
    Publishing date 2021-06-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.29705
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.82: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Voice and Airway Outcomes of Montgomery T-tube Placement in Laryngotracheal Stenosis.

    Miles, Ethan R / Krishna, Priya D / Dehom, Salem / Hahn, Rachel / LaTour, Donn / Murry, Thomas / Crawley, Brianna K

    Journal of voice : official journal of the Voice Foundation

    2022  

    Abstract: Objectives: To describe voice and airway outcomes and complications experienced by patients with laryngotracheal stenosis following Montgomery T-tube placement.: Methods: Retrospective chart review of all patients with laryngotracheal stenosis and ... ...

    Abstract Objectives: To describe voice and airway outcomes and complications experienced by patients with laryngotracheal stenosis following Montgomery T-tube placement.
    Methods: Retrospective chart review of all patients with laryngotracheal stenosis and Montgomery T-tube placement treated at a tertiary referral center from 2012 to 2021.
    Results: Eighteen patients met criteria with laryngotracheal stenosis, seven including the level of the glottis and 11 without glottal involvement. Eleven were completely aphonic before T-tube placement and the remainder had severe dysphonia. There was improvement of Voice Handicap Index-10, Reflux Symptom Index, and GRBAS grade following T-tube placement in patients compared to their preoperative values. Improvement of grade was greater in patients without glottal involvement. Complications of chronic indwelling T-tube included granulation in 14 patients (78%), tracheitis in two patients (11%), and mucus plugging in three patients (17%) with one T-tube related mortality. Five patients were eventually decannulated, six returned to tracheostomy tube, and seven retained the T-tube at last follow-up (average: 30 months, range: 4-80 months).
    Conclusions: Montgomery T-tube placement improves voice in patients with severe dysphonia secondary to laryngotracheal stenosis with and without glottal involvement though the degree of improvement is greater in patients without glottal involvement. T-tube can help reestablish long-term laryngotracheal continuity in patients with no other surgical options. The potential benefits in phonation should be weighed against the possibility of rare but serious adverse events.
    Language English
    Publishing date 2022-07-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 17459-2
    ISSN 1873-4588 ; 1557-8658 ; 0892-1997
    ISSN (online) 1873-4588 ; 1557-8658
    ISSN 0892-1997
    DOI 10.1016/j.jvoice.2022.06.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4034: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Simultaneous exposure to Escherichia coli heat-labile and heat-stable enterotoxins increases fluid secretion and alters cyclic nucleotide and cytokine production by intestinal epithelial cells.

    Read, Lisa T / Hahn, Rachel W / Thompson, Carli C / Bauer, David L / Norton, Elizabeth B / Clements, John D

    Infection and immunity

    2014  Volume 82, Issue 12, Page(s) 5308–5316

    Abstract: Enterotoxigenic Escherichia coli (ETEC) is a significant cause of diarrheal disease and death, especially in children in developing countries. ETEC causes disease by colonizing the small intestine and producing heat-labile toxin (LT), heat-stable toxin ( ... ...

    Abstract Enterotoxigenic Escherichia coli (ETEC) is a significant cause of diarrheal disease and death, especially in children in developing countries. ETEC causes disease by colonizing the small intestine and producing heat-labile toxin (LT), heat-stable toxin (ST), or both LT and ST (LT+ST). The majority of ETEC strains produce both ST and LT. Despite the prevalence of LT+ST-producing organisms, few studies have examined the physiologic or immunologic consequences of simultaneous exposure to these two potent enterotoxins. In the current report, we demonstrate that when LT and ST are both present, they increase water movement into the intestinal lumen over and above the levels observed with either toxin alone. As expected, cultured intestinal epithelial cells increased their expression of intracellular cyclic GMP (cGMP) when treated with ST and their expression of intracellular cyclic AMP (cAMP) when treated with LT. When both toxins were present, cGMP levels but not cAMP levels were synergistically elevated compared with the levels of expression caused by the corresponding single-toxin treatment. Our data also demonstrate that the levels of inflammatory cytokines produced by intestinal epithelial cells in response to LT are significantly reduced in animals exposed to both enterotoxins. These findings suggest that there may be complex differences between the epithelial cell intoxication and, potentially, secretory outcomes induced by ETEC strains expressing LT+ST compared with strains that express LT or ST only. Our results also reveal a novel mechanism wherein ST production may reduce the hosts' ability to mount an effective innate or adaptive immune response to infecting organisms.
    MeSH term(s) Animals ; Bacterial Toxins/toxicity ; Cell Line ; Cytokines/metabolism ; Enterotoxigenic Escherichia coli/immunology ; Enterotoxigenic Escherichia coli/physiology ; Enterotoxins/toxicity ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Escherichia coli Proteins/toxicity ; Female ; Humans ; Mice ; Mice, Inbred BALB C ; Nucleotides, Cyclic/metabolism ; Water/metabolism
    Chemical Substances Bacterial Toxins ; Cytokines ; Enterotoxins ; Escherichia coli Proteins ; Nucleotides, Cyclic ; heat stable toxin (E coli) ; Water (059QF0KO0R) ; heat-labile enterotoxin, E coli (D9K3SN2LNY)
    Language English
    Publishing date 2014-10-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.02496-14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 684: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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