LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Photonics-powered augmented reality skin electronics for proactive healthcare: multifaceted opportunities.

    Taha, Bakr Ahmed / Addie, Ali J / Kadhim, Ahmed C / Azzahran, Ahmad S / Haider, Adawiya J / Chaudhary, Vishal / Arsad, Norhana

    Mikrochimica acta

    2024  Volume 191, Issue 5, Page(s) 250

    Abstract: Rapid technological advancements have created opportunities for new solutions in various industries, including healthcare. One exciting new direction in this field of innovation is the combination of skin-based technologies and augmented reality (AR). ... ...

    Abstract Rapid technological advancements have created opportunities for new solutions in various industries, including healthcare. One exciting new direction in this field of innovation is the combination of skin-based technologies and augmented reality (AR). These dermatological devices allow for the continuous and non-invasive measurement of vital signs and biomarkers, enabling the real-time diagnosis of anomalies, which have applications in telemedicine, oncology, dermatology, and early diagnostics. Despite its many potential benefits, there is a substantial information vacuum regarding using flexible photonics in conjunction with augmented reality for medical purposes. This review explores the current state of dermal augmented reality and flexible optics in skin-conforming sensing platforms by examining the obstacles faced thus far, including technical hurdles, demanding clinical validation standards, and problems with user acceptance. Our main areas of interest are skills, chiroptical properties, and health platform applications, such as optogenetic pixels, spectroscopic imagers, and optical biosensors. My skin-enhanced spherical dichroism and powerful spherically polarized light enable thorough physical inspection with these augmented reality devices: diabetic tracking, skin cancer diagnosis, and cardiovascular illness: preventative medicine, namely blood pressure screening. We demonstrate how to accomplish early prevention using case studies and emergency detection. Finally, it addresses real-world obstacles that hinder fully realizing these materials' extraordinary potential in advancing proactive and preventative personalized medicine, including technical constraints, clinical validation gaps, and barriers to widespread adoption.
    MeSH term(s) Augmented Reality ; Skin ; Precision Medicine ; Electronics ; Delivery of Health Care
    Language English
    Publishing date 2024-04-08
    Publishing country Austria
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-024-06314-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 56/171: Show issues
    Z 8.1: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Targeted delivery of paclitaxel drug using polymer-coated magnetic nanoparticles for fibrosarcoma therapy: in vitro and in vivo studies.

    Al-Obaidy, Rusul / Haider, Adawiya J / Al-Musawi, Sharafaldin / Arsad, Norhana

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 3180

    Abstract: Fibrosarcoma is a rare type of cancer that affects cells known as fibroblasts that are malignant, locally recurring, and spreading tumor in fibrous tissue. In this work, an iron plate immersed in an aqueous solution of double added deionized water, ... ...

    Abstract Fibrosarcoma is a rare type of cancer that affects cells known as fibroblasts that are malignant, locally recurring, and spreading tumor in fibrous tissue. In this work, an iron plate immersed in an aqueous solution of double added deionized water, supplemented with potassium permanganate solution (KMnO
    MeSH term(s) Animals ; Mice ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use ; Paclitaxel/chemistry ; Polymers ; Magnetite Nanoparticles/chemistry ; Antineoplastic Agents/therapeutic use ; Polyethylene Glycols/chemistry ; Fibrosarcoma/drug therapy ; Folic Acid/chemistry ; Nanoparticles/chemistry ; Cell Line, Tumor
    Chemical Substances Paclitaxel (P88XT4IS4D) ; Polymers ; Magnetite Nanoparticles ; Antineoplastic Agents ; poly(ethylene glycol)-folate ; Polyethylene Glycols (3WJQ0SDW1A) ; Folic Acid (935E97BOY8)
    Language English
    Publishing date 2023-02-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-30221-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Uncovering the morphological differences between SARS-CoV-2 and SARS-CoV based on transmission electron microscopy images.

    Taha, Bakr Ahmed / Al Mashhadany, Yousif / Al-Jubouri, Qussay / Haider, Adawiya J / Chaudhary, Vishal / Apsari, Retna / Arsad, Norhana

    Microbes and infection

    2023  Volume 25, Issue 8, Page(s) 105187

    Abstract: Comprehending the morphological disparities between SARS-CoV-2 and SARS-CoV viruses can shed light on the underlying mechanisms of infection and facilitate the development of effective diagnostic tools and treatments. Hence, this study aimed to conduct a ...

    Abstract Comprehending the morphological disparities between SARS-CoV-2 and SARS-CoV viruses can shed light on the underlying mechanisms of infection and facilitate the development of effective diagnostic tools and treatments. Hence, this study aimed to conduct a comprehensive analysis and comparative assessment of the morphology of SARS-CoV-2 and SARS-CoV using transmission electron microscopy (TEM) images. The dataset encompassed 519 isolated SARS-CoV-2 images obtained from patients in Italy (INMI) and 248 isolated SARS-CoV images from patients in Germany (Frankfurt). In this paper, we employed TEM images to scrutinize morphological features, and the outcomes were contrasted with those of SARS-CoV viruses. The findings reveal disparities in the characteristics of SARS-CoV-2 and SARS-CoV, such as envelope protein (E) 98.6 and 102.2 nm, length of spike protein (S) 10.11 and 9.50 nm, roundness 0.86 and 0.88, circularity 0.78 and 0.76, and area sizes 25145.54 and 38591.35 pixels, respectively. In conclusion, these results will augment the identification of virus subtypes, aid in the study of antiviral medications, and enhance our understanding of disease progression and the virus life cycle. Moreover, these findings have the potential to assist in the development of more accurate epidemiological prediction models for COVID-19, leading to better outbreak management and saving lives.
    MeSH term(s) Humans ; SARS-CoV-2/metabolism ; COVID-19 ; Viruses/metabolism ; Antiviral Agents/therapeutic use ; Microscopy, Electron, Transmission
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-07-28
    Publishing country France
    Document type Journal Article
    ZDB-ID 1465093-9
    ISSN 1769-714X ; 1286-4579
    ISSN (online) 1769-714X
    ISSN 1286-4579
    DOI 10.1016/j.micinf.2023.105187
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5014: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Cytotoxicity properties of functionalised carbon nanotubes on pathogenic bacteria.

    Atiyah, Alaa Abdulhasan / Haider, Adawiya J / Dhahi, Randa Mohammed

    IET nanobiotechnology

    2019  Volume 13, Issue 6, Page(s) 597–601

    Abstract: Nanobiotechnology is a promising field concerned with the using of engineered nanomaterials, which leads to the improvement of new human remedial against pathogenic bacteria modalities. In this work, silver nanoparticles (AgNPs) were prepared by an easy, ...

    Abstract Nanobiotechnology is a promising field concerned with the using of engineered nanomaterials, which leads to the improvement of new human remedial against pathogenic bacteria modalities. In this work, silver nanoparticles (AgNPs) were prepared by an easy, cheap and low-cost electro-chemical method. The AgNPs were then loaded successfully on to multi-walled carbon nanotubes (MWCNTs) using a modified chemical reaction process. The AgNPs on the MWCNTs were well spread and evenly distributed on the surfaces of the long nanotubes with well-graphitised walls as examined by high-resolution transmission electron microscopy. X-ray diffraction and transmission electron microscopy were used for sample characterisation. Good dispersion of AgNPs was obtained on the surface of MWCNTs, resulting in an efficient reactivity of the carbon nanotubes surfaces. Finally, the antibacterial activity of AgNPs/MWCNTs hybrid was evaluated against two pathogenic bacteria
    MeSH term(s) Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Bacteria/pathogenicity ; Escherichia coli ; Metal Nanoparticles/chemistry ; Metal Nanoparticles/toxicity ; Microbial Sensitivity Tests ; Microbial Viability/drug effects ; Nanotubes, Carbon/chemistry ; Nanotubes, Carbon/microbiology ; Nanotubes, Carbon/toxicity ; Pseudomonas aeruginosa ; Silver/chemistry ; Silver/pharmacology ; Staphylococcus aureus ; Surface Properties
    Chemical Substances Anti-Bacterial Agents ; Nanotubes, Carbon ; Silver (3M4G523W1G)
    Language English
    Publishing date 2019-08-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2264529-9
    ISSN 1751-875X ; 1751-8741
    ISSN (online) 1751-875X
    ISSN 1751-8741
    DOI 10.1049/iet-nbt.2018.5394
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Gene expression and apoptosis response in hepatocellular carcinoma cells induced by biocompatible polymer/magnetic nanoparticles containing 5-fluorouracil

    Abdul Mahdi, Salih / Ali Kadhim, Afraa / Albukhaty, Salim / Nikzad, Safoora / Haider, Adawiya J / Ibraheem, Sumayah / Ali Kadhim, Haitham / Al-Musawi, Sharafaldin

    Electronic Journal of Biotechnology. 2021 July, v. 52

    2021  

    Abstract: Super-paramagnetic iron oxide nanoparticles (SPION) contain a chemotherapeutic drug and are regarded as a promising technique for improving targeted delivery into cancer cells.In this study, the fabrication of 5-fluorouracil (5-FU) was investigated with ... ...

    Abstract Super-paramagnetic iron oxide nanoparticles (SPION) contain a chemotherapeutic drug and are regarded as a promising technique for improving targeted delivery into cancer cells.In this study, the fabrication of 5-fluorouracil (5-FU) was investigated with loaded Dextran (DEX-SPION) using the co-precipitation technique and conjugated by folate (FA). These nanoparticles (NPs) were employed as carriers and anticancer compounds against liver cancer cells in vitro. Structural, magnetic, morphological characterization, size, and drug loading activities of the obtained FA-DEX-5-FU-SPION NPs were checked using FTIR, VSM, FESEM, TEM, DLS, and zeta potential techniques. The cellular toxicity effect of FA-DEX-5-FU-SPION NPs was evaluated using the MTT test on liver cancer (SNU-423) and healthy cells (LO2). Furthermore, the apoptosis measurement and the expression levels of NF-1, Her-2/neu, c-Raf-1, and Wnt-1 genes were evaluated post-treatment using flow cytometry and RT-PCR, respectively. The obtained NPs were spherical with a suitable dispersity without noticeable aggregation. The size of the NPs, polydispersity, and zeta were 74 ± 13 nm, 0.080 and −45 mV, respectively. The results of the encapsulation efficiency of the nano-compound showed highly colloidal stability and proper drug maintenance. The results indicated that FA-DEX-5-FU-SPION demonstrated a sustained release profile of 5-FU in both phosphate and citrate buffer solutions separately, with higher cytotoxicity against SNU-423 cells than against other cells types. These findings suggest that FA-DEX-SPION NPs exert synergistic effects for targeting intracellular delivery of 5-FU, apoptosis induction, and gene expression stimulation.The findings proved that FA-DEX-5-FU-SPION presented remarkable antitumor properties; no adverse subsequences were revealed against normal cells.How to cite: Mahdia SA, Kadhimb AA, Albukhaty S, et al. Gene expression and apoptosis response in hepatocellular carcinoma cells induced by biocompatible polymer/magnetic nanoparticles containing 5-fluorouracil. Electron J Biotechnol 2021;52. https://doi.org/10.1016/j.ejbt.2021.04.001
    Keywords apoptosis ; biotechnology ; citrates ; coprecipitation ; cytotoxicity ; dextran ; drug therapy ; encapsulation ; flow cytometry ; fluorouracil ; folic acid ; gene expression ; hepatoma ; iron oxides ; magnetism ; phosphates ; polymers ; wnt proteins ; zeta potential
    Language English
    Dates of publication 2021-07
    Size p. 21-29.
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-AP-2-clean
    ISSN 0717-3458
    DOI 10.1016/j.ejbt.2021.04.001
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Smart Nanoformulation Based on Polymeric Magnetic Nanoparticles and Vincristine Drug: A Novel Therapy for Apoptotic Gene Expression in Tumors.

    Al-Musawi, Sharafaldin / Ibraheem, Sumayah / Abdul Mahdi, Salih / Albukhaty, Salim / Haider, Adawiya J / Kadhim, Afraa Ali / Kadhim, Kadhim Ali / Kadhim, Haitham Ali / Al-Karagoly, Hassan

    Life (Basel, Switzerland)

    2021  Volume 11, Issue 1

    Abstract: Background: Advanced nanobiotechnology provides safe and efficient drug delivery systems to deliver chemotherapy that targets cancer cells efficiently.: Methods: A polymeric-magnetic nanocarrier was composed of a dextran (DEX) shell, a ... ...

    Abstract Background: Advanced nanobiotechnology provides safe and efficient drug delivery systems to deliver chemotherapy that targets cancer cells efficiently.
    Methods: A polymeric-magnetic nanocarrier was composed of a dextran (DEX) shell, a superparamagnetic iron oxide (SPION) core and was conjugated with folate (FA) to carry the anticancer drug vincristine (VNC) in Tera-1 testicular tumor cells. The molecular mechanisms by which apoptosis was induced were analyzed using flow cytometry and qPCR, which exhibited anticancer activity of nanoparticles (NPs).
    Results: This nanocarrier revealed a controlled release of VNC in citrate and phosphate buffer solutions that were maintained at pH 5.5 and pH 7.4, respectively. The Inhibitory concentration (IC50) values were greater than 5 mg/mL and displayed ten times higher cytotoxicity than the comparable free drug concentration. The Caspase-9 and P53 expressions were increased, whereas P21 and AKt1 decreased noticeably in the treated cells. The results point to the possible activation of apoptosis following treatment with NPs loaded with vincristine.
    Language English
    Publishing date 2021-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life11010071
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top