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  1. AU="Haider, Kathryn M"
  2. AU="Shang, Hongcai" AU="Shang, Hongcai"
  3. AU="Ho, Collin Elijah Rui Hung"
  4. AU="Akbar, Ansa"
  5. AU="Heinrich, N"
  6. AU="Almeida, Carolina Aparecida de Faria"
  7. AU="Müller, Pavel"
  8. AU="Carosi, Mariantonia"
  9. AU="Bindu Sen"
  10. AU="Kohaut, Eva"
  11. AU="Adam F. Cohen"
  12. AU="Daniele Tomassoni"
  13. AU="Bergado, Gretchen"
  14. AU="Schomberg, Harry H"
  15. AU="Halder, Prolay"
  16. AU="Miyaguchi, Ken"
  17. AU="Zhan, Na-ping"
  18. AU="Stewart Quigg"

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  1. Artikel ; Online: Comparing reactivation and retreatment for three doses of bevacizumab in type 1 retinopathy of prematurity.

    Chopra, Jay / Haider, Kathryn M / Boente, Charline S

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus

    2024  Band 28, Heft 2, Seite(n) 103866

    Abstract: Purpose: To determine timing and rates of reactivation and retreatment of type 1 retinopathy of prematurity (ROP) after treatment with either 0.125 mg, 0.250 mg, or 0.500 mg of intravitreal bevacizumab (IVB).: Methods: Retrospective data, including ... ...

    Abstract Purpose: To determine timing and rates of reactivation and retreatment of type 1 retinopathy of prematurity (ROP) after treatment with either 0.125 mg, 0.250 mg, or 0.500 mg of intravitreal bevacizumab (IVB).
    Methods: Retrospective data, including demographic information, past medical history, and ROP characteristics were analyzed for babies with type 1 ROP treated with IVB at Riley Hospital for Children for the perioed 2014-2021.
    Results: A total of 84 patients met inclusion criteria: 29 patients received 0.125 mg of IVB; 39, 0.250 mg; and 16, 0.500 mg. Of the 84, 67 (80%) had additional laser treatment because of late reactivation (n = 52) or persistent avascular retina (PAR) (n = 15). Subsequent laser treatment was more common with lower doses: 0.125 mg (n = 27 [93%]); 0.250 mg (n = 31 [80%]); 0.500 mg (n = 9 [57%]) (P = 0.012). There was no difference between groups with regard to reason for subsequent laser treatment (reactivation vs PAR). The 0.125 mg group required retreatment because of reactivation 3.8 weeks sooner than the other dosing groups (P = 0.047).
    Conclusions: The outcomes comparing three doses of IVB for severe ROP showed a difference in the timing of secondary treatment, with the lower dosing group requiring laser for reactivation earlier.
    Mesh-Begriff(e) Infant, Newborn ; Infant ; Child ; Humans ; Bevacizumab/therapeutic use ; Angiogenesis Inhibitors/therapeutic use ; Retinopathy of Prematurity/surgery ; Retrospective Studies ; Laser Coagulation ; Intravitreal Injections ; Retreatment ; Gestational Age
    Chemische Substanzen Bevacizumab (2S9ZZM9Q9V) ; Angiogenesis Inhibitors
    Sprache Englisch
    Erscheinungsdatum 2024-03-06
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 1412476-2
    ISSN 1528-3933 ; 1091-8531
    ISSN (online) 1528-3933
    ISSN 1091-8531
    DOI 10.1016/j.jaapos.2024.103866
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Presumed Ocular Histoplasmosis with Choroidal Neovascularization in a 4-year-old.

    Sevgi, Duriye Damla / Haider, Kathryn M / Moorthy, Ramana S

    Ophthalmology. Retina

    2023  Band 7, Heft 10, Seite(n) 917

    Mesh-Begriff(e) Humans ; Child, Preschool ; Histoplasmosis/complications ; Histoplasmosis/diagnosis ; Choroidal Neovascularization/diagnosis ; Eye
    Sprache Englisch
    Erscheinungsdatum 2023-05-22
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2468-6530
    ISSN (online) 2468-6530
    DOI 10.1016/j.oret.2023.04.012
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Using Adult Drug Efficacy Data to Aid in Interpretation of Underpowered Pediatric Studies.

    Haider, Kathryn M / Wallace, David K

    JAMA ophthalmology

    2020  Band 139, Heft 2, Seite(n) 217–218

    Mesh-Begriff(e) Adult ; Child ; Data Interpretation, Statistical ; Evidence-Based Medicine ; Humans ; Infant, Newborn ; Ophthalmia Neonatorum ; Pharmaceutical Preparations
    Chemische Substanzen Pharmaceutical Preparations
    Sprache Englisch
    Erscheinungsdatum 2020-12-17
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2020.5557
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  4. Artikel ; Online: Complications Occurring Through 5 Years Following Primary Intraocular Lens Implantation for Pediatric Cataract.

    Yen, Kimberly G / Repka, Michael X / Sutherland, Desirae R / Haider, Kathryn M / Hatt, Sarah R / Kraker, Raymond T / Galvin, Jennifer A / Li, Zhuokai / Cotter, Susan A / Holmes, Jonathan M

    JAMA ophthalmology

    2023  Band 141, Heft 8, Seite(n) 705–714

    Abstract: Importance: Lensectomy with primary intraocular lens (IOL) implantation is often used in the management of nontraumatic pediatric cataract, but long-term data evaluating the association of age and IOL location with the incidence of complications are ... ...

    Abstract Importance: Lensectomy with primary intraocular lens (IOL) implantation is often used in the management of nontraumatic pediatric cataract, but long-term data evaluating the association of age and IOL location with the incidence of complications are limited.
    Objective: To describe the incidence of complications and additional eye surgeries through 5 years following pediatric lensectomy with primary IOL implantation and association with age at surgery and IOL location.
    Design, setting, and participants: This prospective cohort study used Pediatric Eye Disease Investigator Group cataract registry data from 61 institution- and community-based practices over 3 years (June 2012 to July 2015). Participants were children younger than 13 years without baseline glaucoma who had primary IOL implantation (345 bilateral and 264 unilateral) for nontraumatic cataract. Data analysis was performed between September 2021 and January 2023.
    Exposures: Lensectomy with primary IOL implantation.
    Main outcome and measures: Five-year cumulative incidence of complications by age at surgery (<2 years, 2 to <4 years, 4 to <7 years, and 7 to <13 years) and by IOL location (sulcus vs capsular bag) were estimated using Cox proportional hazards models.
    Results: The cohort included 609 eyes from 491 children (mean [SD] age, 5.6 [3.3] years; 261 [53%] male and 230 [47%] female). Following cataract extraction with primary IOL implantation, a frequent complication was surgery for visual axis opacification (VAO) (cumulative incidence, 32%; 95% CI, 27%-36%). Cumulative incidence was lower with anterior vitrectomy at the time of IOL placement (12%; 95% CI, 8%-16%) vs without (58%; 95% CI, 50%-65%), and the risk of undergoing surgery for VAO was associated with not performing anterior vitrectomy (hazard ratio [HR], 6.19; 95% CI, 3.70-10.34; P < .001). After adjusting for anterior vitrectomy at lens surgery, there were no differences in incidence of surgery for VAO by age at surgery (<2 years, HR, 1.35 [95% CI, 0.63-2.87], 2 to <4 years, HR, 0.86 [95% CI, 0.44-1.68], 4 to <7 years, HR, 1.06 [95% CI, 0.72-1.56]; P = .74) or by capsular bag vs sulcus IOL fixation (HR, 1.22; 95% CI, 0.36-4.17; P = .75). Cumulative incidence of glaucoma plus glaucoma suspect by 5 years was 7% (95% CI, 4%-9%), which did not differ by age after controlling for IOL location and laterality.
    Conclusions and relevance: In this cohort study, a frequent complication following pediatric lensectomy with primary IOL was surgery for VAO, which was associated with primary anterior vitrectomy not being performed but was not associated with age at surgery or IOL location. The risk of glaucoma development across all ages at surgery suggests a need for long-term monitoring.
    Mesh-Begriff(e) Child ; Humans ; Male ; Female ; Child, Preschool ; Lens Implantation, Intraocular/adverse effects ; Lens Implantation, Intraocular/methods ; Cohort Studies ; Prospective Studies ; Visual Acuity ; Cataract Extraction/adverse effects ; Cataract Extraction/methods ; Cataract/etiology ; Cataract/complications ; Glaucoma/epidemiology ; Glaucoma/etiology ; Glaucoma/surgery ; Ocular Hypertension/complications
    Sprache Englisch
    Erscheinungsdatum 2023-06-22
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2023.2335
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Outcomes and Complications 5 Years After Surgery for Pediatric Cataract Associated With Persistent Fetal Vasculature.

    Haider, Kathryn M / Repka, Michael X / Sutherland, Desirae R / Hatt, Sarah R / Fallaha, Nicole / Kraker, Raymond T / Melia, B Michele / Cotter, Susan A / Holmes, Jonathan M

    American journal of ophthalmology

    2023  Band 260, Seite(n) 30–36

    Abstract: Purpose: To report 5-year outcomes after surgery for cataract associated with persistent fetal vasculature (PFV).: Design: Clinical cohort study using pediatric cataract registry data collected annually from medical records.: Methods: This study ... ...

    Abstract Purpose: To report 5-year outcomes after surgery for cataract associated with persistent fetal vasculature (PFV).
    Design: Clinical cohort study using pediatric cataract registry data collected annually from medical records.
    Methods: This study included 64 children <13 years of age who were undergoing surgery for unilateral, nontraumatic cataract associated with PFV. Proportions with age-normal visual acuity (VA) and VA better than 20/200 at 5 years' follow-up were estimated. Cumulative incidences of complications and additional surgeries by 5 years were calculated. Outcomes were compared between eyes with unilateral PFV and eyes with unilateral non-PFV cataract from our registry.
    Results: Forty-eight of 64 eyes were aphakic postoperatively (median age at surgery 2 months [range 1-13 months]) and 16 were pseudophakic (29 months [range 2-92 months]). Overall, 4 of 42 eyes (10% [95% confidence interval {CI} 3%-23%]) achieved age-normal VA. VA better than 20/200 was achieved in 17 (59% [95% CI 39%-76%]) unilateral aphakic PFV eyes and 44 (43% [95% CI 32%-54%]) unilateral non-PFV aphakic eyes (age-adjusted odds ratio = 1.90 [95% CI 0.81-4.50]; P = .14). The most common complication in aphakic PFV eyes was glaucoma-related adverse events (cumulative incidence 24% [95% CI 9%-37%]). There was no significant difference in glaucoma-related adverse events between PFV and non-PFV eyes in aphakic participants ≤1 year of age at lensectomy (age-adjusted hazard ratio = 1.20 [95% CI 0.54-2.64], P = .66).
    Conclusions: A wide range of visual outcomes for PFV cataract were observed with a 10% probability of achieving age-normal VA. There was an ongoing risk for the development of glaucoma-related adverse events in PFV eyes.
    Mesh-Begriff(e) Child ; Humans ; Infant ; Child, Preschool ; Cataract Extraction/adverse effects ; Cohort Studies ; Follow-Up Studies ; Visual Acuity ; Cataract/complications ; Persistent Hyperplastic Primary Vitreous/complications ; Persistent Hyperplastic Primary Vitreous/diagnosis ; Persistent Hyperplastic Primary Vitreous/surgery ; Glaucoma/surgery ; Glaucoma/complications ; Retrospective Studies ; Postoperative Complications/surgery
    Sprache Englisch
    Erscheinungsdatum 2023-11-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2023.11.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Unusual causes of papilledema: Two illustrative cases.

    Nguyen, Ha Son / Haider, Kathryn M / Ackerman, Laurie L

    Surgical neurology international

    2013  Band 4, Seite(n) 60

    Abstract: Background: Neurosurgeons are frequently among the first physicians asked to evaluate patients with papilledema, and the patient is often referred with the implication that they may require shunting. After an initial evaluation to exclude potential ... ...

    Abstract Background: Neurosurgeons are frequently among the first physicians asked to evaluate patients with papilledema, and the patient is often referred with the implication that they may require shunting. After an initial evaluation to exclude potential neurosurgical emergencies, the physician should carefully consider various etiologies of papilledema to prevent unnecessary neurosurgical operations.
    Case description: THE AUTHORS REPORT TWO ILLUSTRATIVE CASES OF UNUSUAL CAUSES OF PAPILLEDEMA: Anemia and leukemic infiltration of the central nervous system. In each case, a complete blood count provided clues for the diagnosis. A review of the literature is also included.
    Conclusions: Both patients responded to medical management/treatment of the underlying disease and did not require neurosurgical operative intervention. Papilledema may be caused by other etiologies besides increased intracranial pressure. The authors present two unusual cases leading to papilledema and provide an outline for the workup of these conditions.
    Sprache Englisch
    Erscheinungsdatum 2013-04-18
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.4103/2152-7806.110686
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Intraoperative apnea in children after buffered 5% povidone-iodine site sterilization for strabismus surgery.

    Emhardt, John D / Haider, Kathryn M / Plager, David A / Grundhoefer, Dava L

    Paediatric anaesthesia

    2015  Band 25, Heft 2, Seite(n) 193–195

    Abstract: Background: Presurgical preparation for ocular surgery typically utilizes a buffered 5% povidone-iodine preparation solution. It was our observation that a significant number of spontaneously ventilating patients under sevoflurane anesthesia would ... ...

    Abstract Background: Presurgical preparation for ocular surgery typically utilizes a buffered 5% povidone-iodine preparation solution. It was our observation that a significant number of spontaneously ventilating patients under sevoflurane anesthesia would become apneic upon ophthalmic instillation of this solution. This study was performed to confirm or refute this observation and to determine whether there were any patient variables that might predict this phenomenon.
    Methods: After Institutional Review Board (IRB) approval, thirty pediatric patients scheduled for strabismus surgery were enrolled. Anesthesia was induced and maintained with sevoflurane via laryngeal mask airway, and all patients were breathing spontaneously. All patients received preoperative sedation with oral midazolam (0.5 kg·kg(-1), maximum 12 mg). Presurgical preparation was performed with saline wash followed by instillation of buffered 5% povidone-iodine solution. Respiratory rate was recorded at the time of surgical preparation. Apnea was defined as lack of respiratory effort for 20 s or greater.
    Results: Data from twenty-eight children (ages 1.4-11 years) were ultimately recorded. Fifteen of the twenty-eight patients developed apnea (median duration 40, IQR 37, range 20-262 s) at the time of surgical site preparation.
    Conclusions: Apnea at the time of ocular preparation with buffered 5% povidone-iodine solution is common. The precise mechanism of this response is unknown.
    Mesh-Begriff(e) Anti-Infective Agents, Local/adverse effects ; Apnea/chemically induced ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Intraoperative Complications ; Male ; Povidone-Iodine/adverse effects ; Preoperative Care/adverse effects ; Preoperative Care/methods ; Strabismus/surgery
    Chemische Substanzen Anti-Infective Agents, Local ; Povidone-Iodine (85H0HZU99M)
    Sprache Englisch
    Erscheinungsdatum 2015-02
    Erscheinungsland France
    Dokumenttyp Journal Article
    ZDB-ID 1086049-6
    ISSN 1460-9592 ; 1155-5645
    ISSN (online) 1460-9592
    ISSN 1155-5645
    DOI 10.1111/pan.12476
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Visual Acuity and Ophthalmic Outcomes 5 Years After Cataract Surgery Among Children Younger Than 13 Years.

    Repka, Michael X / Dean, Trevano W / Kraker, Raymond T / Li, Zhuokai / Yen, Kimberly G / de Alba Campomanes, Alejandra G / Young, Marielle P / Rahmani, Bahram / Haider, Kathryn M / Whitehead, George F / Lambert, Scott R / Kurup, Sudhi P / Kraus, Courtney L / Cotter, Susan A / Holmes, Jonathan M

    JAMA ophthalmology

    2022  Band 140, Heft 3, Seite(n) 269–276

    Abstract: Importance: Cataract is an important cause of visual impairment in children. Data from a large pediatric cataract surgery registry can provide real-world estimates of visual outcomes and the 5-year cumulative incidence of adverse events.: Objective: ... ...

    Abstract Importance: Cataract is an important cause of visual impairment in children. Data from a large pediatric cataract surgery registry can provide real-world estimates of visual outcomes and the 5-year cumulative incidence of adverse events.
    Objective: To assess visual acuity (VA), incidence of complications and additional eye operations, and refractive error outcomes 5 years after pediatric lensectomy among children younger than 13 years.
    Design, setting, and participants: This prospective cohort study used data from the Pediatric Eye Disease Investigator Group clinical research registry. From June 2012 to July 2015, 61 eye care practices in the US, Canada, and the UK enrolled children from birth to less than 13 years of age who had undergone lensectomy for any reason during the preceding 45 days. Data were collected from medical record reviews annually thereafter for 5 years until September 28, 2020.
    Exposures: Lensectomy with or without implantation of an intraocular lens (IOL).
    Main outcomes and measures: Best-corrected VA and refractive error were measured from 4 to 6 years after the initial lensectomy. Cox proportional hazards regression was used to assess the 5-year incidence of glaucoma or glaucoma suspect and additional eye operations. Factors were evaluated separately for unilateral and bilateral aphakia and pseudophakia.
    Results: A total of 994 children (1268 eyes) undergoing bilateral or unilateral lensectomy were included (504 [51%] male; median age, 3.6 years; range, 2 weeks to 12.9 years). Five years after the initial lensectomy, the median VA among 701 eyes with available VA data (55%) was 20/63 (range, 20/40 to 20/100) in 182 of 316 bilateral aphakic eyes (58%), 20/32 (range, 20/25 to 20/50) in 209 of 386 bilateral pseudophakic eyes (54%), 20/200 (range, 20/50 to 20/618) in 124 of 202 unilateral aphakic eyes (61%), and 20/65 (range, 20/32 to 20/230) in 186 of 364 unilateral pseudophakic eyes (51%). The 5-year cumulative incidence of glaucoma or glaucoma suspect was 46% (95% CI, 28%-59%) in participants with bilateral aphakia, 7% (95% CI, 1%-12%) in those with bilateral pseudophakia, 25% (95% CI, 15%-34%) in those with unilateral aphakia, and 17% (95% CI, 5%-28%) in those with unilateral pseudophakia. The most common additional eye surgery was clearing the visual axis, with a 5-year cumulative incidence of 13% (95% CI, 8%-17%) in participants with bilateral aphakia, 33% (95% CI, 26%-39%) in those with bilateral pseudophakia, 11% (95% CI, 6%-15%) in those with unilateral aphakia, and 34% (95% CI, 28%-39%) in those with unilateral pseudophakia. The median 5-year change in spherical equivalent refractive error was -8.38 D (IQR, -11.38 D to -2.75 D) among 89 bilateral aphakic eyes, -1.63 D (IQR, -3.13 D to -0.25 D) among 130 bilateral pseudophakic eyes, -10.75 D (IQR, -20.50 D to -4.50 D) among 43 unilateral aphakic eyes, and -1.94 D (IQR, -3.25 D to -0.69 D) among 112 unilateral pseudophakic eyes.
    Conclusions and relevance: In this cohort study, development of glaucoma or glaucoma suspect was common in children 5 years after lensectomy. Myopic shift was modest during the 5 years after placement of an intraocular lens, which should be factored into implant power selection. These results support frequent monitoring after pediatric cataract surgery to detect glaucoma, visual axis obscuration causing reduced vision, and refractive error.
    Mesh-Begriff(e) Aphakia/complications ; Aphakia, Postcataract/epidemiology ; Aphakia, Postcataract/etiology ; Cataract/etiology ; Cataract Extraction/adverse effects ; Cataract Extraction/methods ; Child ; Child, Preschool ; Cohort Studies ; Female ; Follow-Up Studies ; Glaucoma/diagnosis ; Glaucoma/epidemiology ; Glaucoma/etiology ; Humans ; Infant ; Lens Implantation, Intraocular/adverse effects ; Male ; Ocular Hypertension/etiology ; Prospective Studies ; Pseudophakia/epidemiology ; Refractive Errors/complications ; Vision Disorders/etiology ; Visual Acuity
    Sprache Englisch
    Erscheinungsdatum 2022-02-10
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2021.6176
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Hemangiomas treated with propranolol: do the rewards outweigh the risks?

    Haider, Kathryn M / Neely, Daniel E / Plager, David A

    The American orthoptic journal

    2013  Band 63, Seite(n) 2–5

    Abstract: Recent reports of propranolol for the treatment of hemangiomas have led many physicians to question the best treatment strategy for children with vision-threatening hemangiomas. Although propranolol has potential side effects, including hypoglycemia and ... ...

    Abstract Recent reports of propranolol for the treatment of hemangiomas have led many physicians to question the best treatment strategy for children with vision-threatening hemangiomas. Although propranolol has potential side effects, including hypoglycemia and hypotension, early studies suggest it is more efficacious than systemic cortico steroids with a lower incidence of adverse side effects.
    Mesh-Begriff(e) Adrenergic beta-Antagonists/therapeutic use ; Child ; Hemangioma/drug therapy ; Humans ; Orbital Neoplasms/drug therapy ; Propranolol/therapeutic use ; Treatment Outcome
    Chemische Substanzen Adrenergic beta-Antagonists ; Propranolol (9Y8NXQ24VQ)
    Sprache Englisch
    Erscheinungsdatum 2013
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 219397-8
    ISSN 1553-4448 ; 0065-955X
    ISSN (online) 1553-4448
    ISSN 0065-955X
    DOI 10.3368/aoj.63.1.2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Immediate Postoperative Alignment Measurements as a Predictor of Alignment Stability in Fixed Suture Strabismus Surgery.

    Boente, Charline S / Jardine, Griffin J / Damarjian, Tina G / Sprunger, Derek T / Roberts, Gavin J / Neely, Daniel E / Haider, Kathryn M / Plager, David A

    Journal of pediatric ophthalmology and strabismus

    2018  Band 55, Heft 4, Seite(n) 240–244

    Abstract: Purpose: To evaluate the use of immediate postoperative alignment measurements as a predictor of future alignment stability in fixed suture strabismus surgery.: Methods: Forty-seven patients were prospectively evaluated after undergoing horizontal or ...

    Abstract Purpose: To evaluate the use of immediate postoperative alignment measurements as a predictor of future alignment stability in fixed suture strabismus surgery.
    Methods: Forty-seven patients were prospectively evaluated after undergoing horizontal or vertical rectus muscle surgery using a fixed suture technique. Alignment measurements were taken approximately 1 hour, 1 to 3 weeks, and 2 to 3 months postoperatively. A Spearman correlation coefficient was used to compare measurements from the immediate postoperative period to the 2- to 3-month postoperative period. Patients with dissociated strabismus, only oblique muscle surgery, or poor vision in one or both eyes precluding precise alternate cover test were excluded.
    Results: Mean age of all patients was 46.7 years (range: 12 to 86 years). Twenty-two patients underwent surgery for exotropia: 19 for esotropia and 6 for hypertropia. Mean alignment for all surgeries was 2 prism diopters (PD) undercorrection in the immediate postoperative period, which was similar to the mean of 4.6 PD undercorrection at 2 to 3 months postoperatively. However, the Spearman correlation between the immediate postoperative and 2- to 3-month postoperative measurements was 0.18 for all surgeries, 0.03 for exotropia, 0.56 for esotropia, and 0.40 for hypertropia. The overall success rate, defined as 8 PD or less of horizontal deviation and 4 PD or less of vertical deviation, was 77% at 2 to 3 months postoperatively.
    Conclusions: The relationship between immediate postoperative alignment and future alignment stability in fixed suture strabismus surgery has not been previously defined. The current study demonstrated that although the surgical success rate was reasonably good, poor correlation occurred between the alignment immediately postoperatively and 2 to 3 months postoperatively. [J Pediatr Ophthalmol Strabismus. 2018;55(4):240-244.].
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Female ; Humans ; Male ; Middle Aged ; Oculomotor Muscles/physiopathology ; Oculomotor Muscles/surgery ; Ophthalmologic Surgical Procedures ; Postoperative Period ; Prospective Studies ; Strabismus/physiopathology ; Strabismus/surgery ; Suture Techniques ; Sutures ; Vision, Binocular/physiology ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2018-07-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 800921-1
    ISSN 1938-2405 ; 0191-3913
    ISSN (online) 1938-2405
    ISSN 0191-3913
    DOI 10.3928/01913913-20180213-06
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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