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Article ; Online: Fungus-Based MnO/Porous Carbon Nanohybrid as Efficient Laccase Mimic for Oxygen Reduction Catalysis and Hydroquinone Detection

Haoran Ge / Hailong Zhang

Nanomaterials, Vol 12, Iss 1596, p

2022 Volume 1596

Abstract: Developing efficient laccase-mimicking nanozymes via a facile and sustainable strategy is intriguing in environmental sensing and fuel cells. In our work, a MnO/porous carbon (MnO/PC) nanohybrid based on fungus was synthesized via a facile carbonization ... ...

Abstract	Developing efficient laccase-mimicking nanozymes via a facile and sustainable strategy is intriguing in environmental sensing and fuel cells. In our work, a MnO/porous carbon (MnO/PC) nanohybrid based on fungus was synthesized via a facile carbonization route. The nanohybrid was found to possess excellent laccase-mimicking activity using 2,2′-azinobis (3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt (ABTS) as the substrate. Compared with the natural laccase and reported nanozymes, the MnO/PC nanozyme had much lower K m value. Furthermore, the electrochemical results show that the MnO/PC nanozyme had high electrocatalytic activity toward the oxygen reduction reaction (ORR) when it was modified on the electrode. The hybrid nanozyme could catalyze the four-electron ORR, similar to natural laccase. Moreover, hydroquinone (HQ) induced the reduction of oxABTS and caused the green color to fade, which provided colorimetric detection of HQ. A desirable linear relationship (0–50 μM) and detection limit (0.5 μM) were obtained. Our work opens a simple and sustainable avenue to develop a carbon–metal hybrid nanozyme in environment and energy applications.
Keywords	fungus ; nanozyme ; laccase ; oxygen reduction reaction ; hydroquinone detection ; Chemistry ; QD1-999
Subject code	540
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Electric-Thermal Uneven Characteristics Simulation of Wide Mg Alloy Strip and Electroplastic Rolling Experiment

Gengliang Liu / Lipo Yang / Hailong Zhang

Applied Sciences, Vol 13, Iss 2772, p

2023 Volume 2772

Abstract: In order to solve the problem of wide magnesium strip uneven deformation in electroplastic rolling, an uneven field measurement device was designed. The device simulates the actual electro-thermal characteristics and provides as even and constant field ... ...

Abstract	In order to solve the problem of wide magnesium strip uneven deformation in electroplastic rolling, an uneven field measurement device was designed. The device simulates the actual electro-thermal characteristics and provides as even and constant field conditions as possible for high-efficiency wide Mg strip rolling. Firstly, the effect of electrode position and distance on the electric field unevenness of magnesium strip is observed by setting the electric rolling condition, to provide the optimal electrical-thermal field quantity coupling conditions required by electric rolling. Secondly, in order to reveal the changing trend of the transient field in the actual rolling, the three-dimensional electric field of wide magnesium strip are simulated by the finite element method. The results show that the even temperature field and stable stress field required by the EPR of a wide Mg strip can be guaranteed to the greatest extent by setting electric field parameter Online. The case proves that the continuous EPR of Mg strip with a thickness of less than 0.13 mm without heat treatment can be realized by fine control of the EPR process.
Keywords	electroplastic rolling ; uneven electric field ; multi-field coupling ; wide Mg alloy strip ; fine control method ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	600
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Efficient Massive MIMO Detection for M-QAM Symbols

Zhi Quan / Jiyu Luo / Hailong Zhang / Li Jiang

Entropy, Vol 25, Iss 391, p

2023 Volume 391

Abstract: Massive multiple-input multiple-output (MIMO) systems significantly outperform small-scale MIMO systems in terms of data rate, making them an enabling technology for next-generation wireless systems. However, the increased number of antennas increases ... ...

Abstract	Massive multiple-input multiple-output (MIMO) systems significantly outperform small-scale MIMO systems in terms of data rate, making them an enabling technology for next-generation wireless systems. However, the increased number of antennas increases the computational difficulty of data detection, necessitating more efficient detection techniques. This paper presents a detector based on joint deregularized and box-constrained dichotomous coordinate descent (BOXDCD) with iterations for rectangular m-ary quadrature amplitude modulation (M-QAM) symbols. Deregularization maximized the energy of the solution. With the box-constraint, the deregularization forces the solution to be close to the rectangular boundary set. The numerical results demonstrate that the proposed detector achieves a considerable performance gain compared to existing detection algorithms. The performance advantage increases with the system size and signal-to-noise ratio.
Keywords	box-constrained dichotomous coordinate descent ; massive MIMO ; negative diagonal loading regularization ; signal detection ; quadrature amplitude modulation ; Science ; Q ; Astrophysics ; QB460-466 ; Physics ; QC1-999
Subject code	003
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Incorporation of the

Tao, Ye / Luan, Ni / Yang, Chunyun / Sun, Jiayu / Li, Kai / Dai, Xing / Hailong Zhang / Zhifang Chai / Wang, Shuao / Wang, Yaxing

Journal of the American Chemical Society

2024

Abstract: We present the first example of ... ...

Abstract	We present the first example of an
Language	English
Publishing date	2024-03-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c13514
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Article: Exploration of biomarkers for efficacy evaluation of traditional Chinese medicine syndromes of acute exacerbation of chronic obstructive pulmonary disease based on metabolomics.

Hailong, Zhang / Yimei, Si / Yan, Du / Xinguang, Liu / Jiansheng, Li

Frontiers in pharmacology

2024 Volume 15, Page(s) 1302950

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2024-01-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2024.1302950
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Article ; Online: Optimization design of optical windows for deep-sea pressure-resistant structures based on transition materials

Yucong Wei / Guoliang Ma / Hailong Zhang / Xiaowei Zhang / Xiangqian Quan

Frontiers in Marine Science, Vol

2023 Volume 10

Abstract: IntroductionThe design of high-pressure optical windows is one of the key tasks in deep-sea exploration, as it directly determines the reliability and maximum operating depth of underwater optical equipment.MethodIn this paper, mechanical modeling and ... ...

Abstract	IntroductionThe design of high-pressure optical windows is one of the key tasks in deep-sea exploration, as it directly determines the reliability and maximum operating depth of underwater optical equipment.MethodIn this paper, mechanical modeling and finite element analysis methods are employed to study optical windows.Results and discussionResults show that changes in boundary conditions during loading significantly affect the stress distribution of the window. Based on this conclusion, an optimization design method is proposed, which involves the use of transition materials to reduce the impact of base deformation on the window. The study further analyzes the effects of the transition material’s Young’s modulus, Poisson’s ratio, thickness, and friction coefficient on the stress of the optical window. A calculation method for material selection criteria is proposed to select appropriate transition materials, and actual materials are used for verification. Finally, the reliability of the optimization design scheme based on transition materials is confirmed through high-pressure experiments.
Keywords	pressure-resistant structure ; optical window design ; finite element analysis ; mechanical model analysis ; optimized design scheme ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
Subject code	621
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Facility Layout Algorithm for Logistics Scenarios Driven by Transport Lines

Fulin Jiang / Lin Li / Yiming Tang / Hailong Zhang / Xiaoping Liu

Applied Sciences, Vol 13, Iss 7215, p

2023 Volume 7215

Abstract: The layout of facilities in a logistics scenario involves not only the working facilities responsible for processing materials but also the transport lines responsible for transporting materials. The traditional facility layout methods do not take into ... ...

Abstract	The layout of facilities in a logistics scenario involves not only the working facilities responsible for processing materials but also the transport lines responsible for transporting materials. The traditional facility layout methods do not take into account the transportation facilities nor calculate the material handling cost by Manhattan distance, thus failing to fulfill the actual requirements of industrial logistics scenarios. In this paper, a facility layout algorithm framework MOSA-FD driven by transport lines is proposed. A multi-objective simulated annealing (MOSA) algorithm is designed for both material handling cost (MHC) and transport facility cost (TFC) objectives. Then, a force-directed (FD) algorithm is applied to correct the unreasonable solutions according to the material transport lines in the logistics workshop, and a better solution is quickly obtained. Finally, by comparing the results with those of other metaheuristic multi-objective algorithms, the acceleration of the force-directed algorithm in this layout problem is demonstrated in experimental instances of different scales, and our method, compared to the MOSA algorithm, can reach optimal ratios of 36% and 80%, respectively, on the multi-objective.
Keywords	logistics facilities layout problem ; multi-objective optimization ; force-directed algorithm ; collaborative computing ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	670
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impacts of Corn Straw Compost on Rice Growth and Soil Microflora under Saline-Alkali Stress

Shenglin Li / Lixin Li / Zhigang Wang / Jing Sun / Hailong Zhang

Agronomy, Vol 13, Iss 1525, p

2023 Volume 1525

Abstract: Saline–alkali soil seriously inhibits crop growth and yields and threatens the sustainable development of agriculture. Corn straw compost can alleviate saline–alkali stress and improve crop growth and development. In this study, we demonstrate that corn ... ...

Abstract	Saline–alkali soil seriously inhibits crop growth and yields and threatens the sustainable development of agriculture. Corn straw compost can alleviate saline–alkali stress and improve crop growth and development. In this study, we demonstrate that corn straw compost (CSC) improved soil physicochemical properties, e.g., decreased pH and electrical conductivity (EC), but increased soil nutrients, e.g., available nitrogen and phosphorus, and soluble organic carbon, as well as activities of sucrase and urease in saline–alkali soil. CSC affected the structure of water-stable aggregates (WSA) and the composition of soil microflora in saline–alkali soil. With the increase in the content of CSC, the abundances of some genera, e.g., Thermobacillus , Thermopolyspora , and Thermobispora , were significantly increased, suggesting that they play an important role in improving soil nutrient components and physicochemical properties, which subsequently improved plant growth and development. Consequently, the biomass and yields of rice grown in saline–alkali soil were greatly improved. In conclusion, CSC can improve saline–alkali soil activities and microbial communities, thus improving crop growth and yields. Our findings provide a theoretical basis for the sustainable development of modern agriculture.
Keywords	physicochemical properties ; soil structure ; 16S rRNA sequencing ; bacterial community ; correlation ; rice biomass and yields ; Agriculture ; S
Subject code	630
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Detailed studies on the anticancer action of rosmarinic acid in human Hep-G2 liver carcinoma cells: evaluating its effects on cellular apoptosis, caspase activation and suppression of cell migration and invasion.

Chen, Xue / Su, Hailong Zhang Zhejun

Journal of B.U.ON. : official journal of the Balkan Union of Oncology

2020 Volume 25, Issue 4, Page(s) 2011–2016

Abstract: Purpose: Oral cancer is one among the devastating types of malignancies and imposes tremendous disease burden on humans. This study was undertaken to investigate the anticancer properties of a plant-derived flavanone, Blumeatin, against human oral ... ...

Abstract	Purpose: Oral cancer is one among the devastating types of malignancies and imposes tremendous disease burden on humans. This study was undertaken to investigate the anticancer properties of a plant-derived flavanone, Blumeatin, against human oral cancer cells. Additionally, this study also attempted to unreveal the molecular mechanisms responsible for the anticancer properties of this molecule. Methods: MTT assay was used for the assessment of cell viability. Transwell and wound healing assays were used for the determination of cell invasion and migration, respectively. Comet assay was used for the determination of cell viability. Transmission electron microscopy (TEM) analysis was done to assess the induction of autophagy. The protein expression was determined by western blot analysis. Results: Blumeatin inhibited the growth of SCC-4 oral cancer cells with minimal cytotoxic effects against the normal hTRET-OME cells. The flow cytometric analysis showed that Blumeatin triggers DNA damage in the SCC-4 cells. Blumeatin also activated autophagy in SCC-4 cells which was accompanied with upregulation of LC3B and Beclin 1. This molecule also increased ROS and decreased the MMP levels in human SCC-4 cells. The effects of Blumeatin were also examined on the migration and invasion of the SCC-4 cells and it was revealed that the molecule suppresses both migration and invasion of the SCC-4 oral cancer cells. Conclusion: This study indicates that Blumeatin exhibits potent anticancer effects and points towards its use in the development of a new systemic therapy for oral cancer.
MeSH term(s)	Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Apoptosis/drug effects ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Caspases/metabolism ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cinnamates/pharmacology ; Depsides/pharmacology ; Hep G2 Cells ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Neoplasm Invasiveness ; Rosmarinic Acid
Chemical Substances	Anti-Inflammatory Agents, Non-Steroidal ; Cinnamates ; Depsides ; Caspases (EC 3.4.22.-)
Language	English
Publishing date	2020-10-25
Publishing country	Cyprus
Document type	Journal Article
ZDB-ID	2040386-0
ISSN	2241-6293 ; 1107-0625
ISSN (online)	2241-6293
ISSN	1107-0625
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Article ; Online: A sustainable natural clam shell derived photocatalyst for the effective adsorption and photodegradation of organic dyes

Ting Qu / Xinxin Yao / Gary Owens / Liangjun Gao / Hailong Zhang

Scientific Reports, Vol 12, Iss 1, Pp 1-

2022 Volume 14

Abstract: Abstract In response to an increasing desire for modern industries to be both green and sustainable, there has been increasing research focus on the reutilization of natural waste materials to effectively remove and degrade toxic wastewater effluents. ... ...

Abstract	Abstract In response to an increasing desire for modern industries to be both green and sustainable, there has been increasing research focus on the reutilization of natural waste materials to effectively remove and degrade toxic wastewater effluents. One interesting food industry waste product is clam shell. Here a new photocatalytic nanomaterial derived from marine clam shells was successfully prepared and characterized. Thereafter the material was applied for the removal of two target dyes from aqueous solution, where the effect of both catalyst dose and initial dye concentration on adsorption and photocatalysis was investigated. The maximum adsorption capacities of methylene blue (100 mg/L) and Congo red (500 mg/L) were 123.45 mg/g and 679.91 mg/g, respectively, where adsorption followed pseudo second order kinetics predominantly via a chemical adsorption process. The photodegradation removal efficiencies of the two dye solutions under visible light irradiation were 99.6% and 83.3% for MB and CR, respectively. The excellent degradation performance in a mixed dye solution, with strong degradation capability and low cost, demonstrated that the clam shell catalyst material was a good candidate for practical field remediation of dye contaminated wastewater.
Keywords	Medicine ; R ; Science ; Q
Subject code	660
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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