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Article ; Online: Accurate Extraction of Cableways Based on the LS-PCA Combination Analysis Method

Wenxin Wang / Changming Zhao / Haiyang Zhang

Applied Sciences, Vol 13, Iss 2875, p

2023 Volume 2875

Abstract: In order to maintain a ski resort efficiently, regular inspections of the cableways are essential. However, there are some difficulties in discovering and observing the cable car cableways in the ski resort. This paper proposes a high-precision ... ...

Abstract	In order to maintain a ski resort efficiently, regular inspections of the cableways are essential. However, there are some difficulties in discovering and observing the cable car cableways in the ski resort. This paper proposes a high-precision segmentation and extraction method based on the 3D laser point cloud data collected by airborne lidar to address these problems. In this method, first, an elevation filtering algorithm is used to remove ground points and low-height vegetation, followed by preliminary segmentation of the cableway using the spatial distribution characteristics of the point cloud. The ropeway segmentation and extraction are then completed using the least squares-principal component combination analysis method for parameter fitting. Additionally, we selected three samples of data from the National Alpine Ski Center to be used as test objects. The real value is determined by the number of point clouds manually deducted by CloudCompare. The extraction accuracy is defined as the ratio of the number of point clouds extracted by the algorithm to the number of point clouds manually extracted. While the environmental complexities of the samples differ, the algorithm proposed in this paper is capable of segmenting and extracting cableways with great accuracy, achieving a comprehensive and effective extraction accuracy rate of 90.59%, which is sufficient to meet the project’s requirements.
Keywords	ropeway of cable car ; adaptation ; segmentation and extraction ; spatial distribution characteristics ; least squares-principal component analysis ; extraction accuracy ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	518
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Influence of Organic Amendments Based on Garden Waste for Microbial Community Growth in Coastal Saline Soil

Jingnan Li / Haiyang Zhang / Li Zheng

Sustainability, Vol 15, Iss 5038, p

2023 Volume 5038

Abstract: Garden waste compost (GWC) has been applied as an amendment to improve the desalination efficiency, nutrient availability and diversity of the microbial community in coastal saline soil. Understanding the response of the microbial community to garden ... ...

Abstract	Garden waste compost (GWC) has been applied as an amendment to improve the desalination efficiency, nutrient availability and diversity of the microbial community in coastal saline soil. Understanding the response of the microbial community to garden waste compost application is of great significance in coastal ecological restoration. Four treatments were established: CK, nonamended control; T1, application of 68 kg·m −3 garden waste compost; T2, application of 15 kg·m −3 bentonite; and T3, a mixture of garden waste compost and bentonite. In addition, soil physicochemical properties, soil enzymes, microbial biomass carbon and the soil microbial community were measured. The results show that T3 had a more significant effect on increasing soil enzymes, as well as microbial biomass carbon and nitrogen, urease, sucrase and dehydrogenase activities. Based on the relative abundance, microbial diversity and linear discriminant effect size (LEfSe) analyses, the amendments can be seen to have increased the microbial abundance and alpha diversity of the bacterial structure and also altered the microbial community structure. RDA and Pearson correlation analysis at the phylum level indicated that available nitrogen, total porosity, hydraulic conductivity, bulk density and EC were the primary determinants of microbial communities associated with this amendment. In conclusion, the application of garden waste compost enables more microorganisms to participate in the soil material cycle, indicating that garden waste composting is beneficial to the restoration of coastal soils.
Keywords	garden waste compost ; coastal saline soil ; microbial community structure ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	710
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Research on the Calculation and Analysis of Ski-Track Areas Based on Laser Point Clouds

Wenxin Wang / Changming Zhao / Haiyang Zhang

Applied Sciences, Vol 13, Iss 1632, p

2023 Volume 1632

Abstract: To address the long-term statistical problem of ski-track area in the construction and operation of ski resorts, we propose a new ski-track point cloud boundary extraction method that improves the accuracy of boundary extraction and minimizes the offset ... ...

Abstract	To address the long-term statistical problem of ski-track area in the construction and operation of ski resorts, we propose a new ski-track point cloud boundary extraction method that improves the accuracy of boundary extraction and minimizes the offset of the area error. In this method, all point clouds are first projected onto the fitting plane using the random sample consensus (RANSAC) method. An improved point cloud boundary extraction algorithm is used to triangulate and extract the high-precision ski-track boundary. A discrete Green formula is then used to calculate and count the ski track’s exact area. It is demonstrated through five sets of test experiments that the error offset of the method proposed in this paper is smaller than that of other classical methods, which confirms its benefits and feasibility.
Keywords	laser point clouds ; ski-track area ; boundary extraction ; discrete Green formula ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	310
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Research on echo characteristics in remote detection with the pulse LiDAR of aerial targets under diverse atmospheric conditions

Si Chen / Haiyang Zhang / Fahong Jin / Lin Wang / Changming Zhao

Heliyon, Vol 9, Iss 6, Pp e16728- (2023)

2023

Abstract: This paper utilizes the idea of theoretical analysis to introduce a method for echo characteristics in remote detection with the pulse LiDAR of aerial targets under atmospheric conditions. A Missiles and an aircraft are selected as simulation targets. ... ...

Abstract	This paper utilizes the idea of theoretical analysis to introduce a method for echo characteristics in remote detection with the pulse LiDAR of aerial targets under atmospheric conditions. A Missiles and an aircraft are selected as simulation targets. The relation among mutual mapping of target surface elements can be directly gained by setting light source and target parameters. We discuss influences on atmospheric transport conditions, target shapes and detection conditions on echo characteristics. Atmospheric transport model is introduced as weather conditions, including sunny and cloudy days, with or without turbulence. Simulation results conclude that the outline of scanned waveform can invert the target shape. These provide a theoretical basis for improving the target detection and tracking performance.
Keywords	The pulse LiDAR ; Aerial targets ; Echo characteristics ; Atmospheric conditions ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	380
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Investigating the Mechanism of Continuous–Discrete Coupled Destabilization of Roadway-Surrounding Rocks in Weakly Cemented Strata under Varying Levels of Moisture Content

Lihui Sun / Zhixin Jiang / Yaxin Long / Qingfeng He / Haiyang Zhang

Processes, Vol 11, Iss 2556, p

2023 Volume 2556

Abstract: This study examines frequent disasters, including large-scale deformation and collapse, caused by underground mining in weakly cemented strata in Western China. The weakly cemented rock’s unique characteristics, including low strength and easy ... ...

Abstract	This study examines frequent disasters, including large-scale deformation and collapse, caused by underground mining in weakly cemented strata in Western China. The weakly cemented rock’s unique characteristics, including low strength and easy disintegration, demonstrate a different damage pattern than that traditionally seen in the central and eastern regions. Using Fast Lagrangian Analysis of Continua-Particle Flow Code (FLAC2D-PFC2D) coupling, we model the strata, focusing on the 3-1 coal seam roadway at Hongqinghe mine. This study investigates the damage–rupture–destabilization progression in the peripheral rock under varying levels of moisture content. Our findings indicate that a water content of ω = 5.5% is the threshold for roadway damage, and moisture content <5.5% yields minimal rock deformation. However, moisture content >5.5% abruptly increases cracks and shifts the rock’s force chain, causing significant deformation and affecting the ceiling the most. Moreover, higher levels of moisture content weaken the anchor solid’s performance, with two primary failure modes: anchor interface slippage (comprising five stages: elasticity, elasticity–shear hardening, elasticity–shear hardening–decohesion, shear hardening–decohesion, and decohesion) and shear damage. These insights are vital for improving numerical simulations of underground mining, obtaining a more accurate understanding of mineral pressure disasters in weakly cemented strata mining regions in Western China, and developing a solid foundation for the better control of such strata.
Keywords	continuous–discrete ; moisture content ; weakly cemented rock ; destabilization mechanism ; anchorage failure mechanism ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
Subject code	669
Language	English
Publishing date	2023-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Computational Investigation of Structural Basis for Enhanced Binding of Isoflavone Analogues with Mitochondrial Aldehyde Dehydrogenase

Yongguang Zhang / Yejie Qiu / Haiyang Zhang

ACS Omega, Vol 7, Iss 9, Pp 8115-

2022 Volume 8127

Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A New Method of Ski Tracks Extraction Based on Laser Intensity Information

Wenxin Wang / Changming Zhao / Haiyang Zhang

Applied Sciences, Vol 12, Iss 5678, p

2022 Volume 5678

Abstract: At present, the mainstream laser point cloud classification algorithms are mainly based on the geometric information of the target. Nevertheless, if there is occlusion between the targets, the classification effect will be negatively affected. Compared ... ...

Abstract	At present, the mainstream laser point cloud classification algorithms are mainly based on the geometric information of the target. Nevertheless, if there is occlusion between the targets, the classification effect will be negatively affected. Compared with the above methods, a new method of ski tracks extraction using laser intensity information based on target reflection is presented in this paper. The method can complete the downsampling of the point cloud datasets of ski tracks under the condition that the information of the target edge is complete. Then, the clustering and extraction of ski tracks are effectively accomplished based on the smoothing threshold and curvature between adjacent point clouds. The experimental results show that, different from the traditional methods, the composite classification method based on the intensity information proposed in this paper can effectively extract ski tracks from the complex background. By comparing the proposed method to the Euclidean distance method, the clustering segmentation method, and the RANSAC method, the average extraction accuracy is increased by 16.9%, while the over extraction rate is reduced by 8.4% and the under extraction rate is reduced by 8.6%, allowing us to accurately extract the ski track point cloud of a ski resort.
Keywords	classification algorithms ; smoothing threshold and curvature ; laser intensity information ; ski tracks ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	006
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Atomistic Simulation of Lysozyme in Solutions Crowded by Tetraethylene Glycol

Donglin Liu / Yejie Qiu / Qing Li / Haiyang Zhang

Molecules, Vol 27, Iss 2110, p

Force Field Dependence

2022 Volume 2110

Abstract: The behavior of biomolecules in crowded environments remains largely unknown due to the accuracy of simulation models and the limited experimental data for comparison. Here we chose a small crowder of tetraethylene glycol (PEG-4) to investigate the self- ... ...

Abstract	The behavior of biomolecules in crowded environments remains largely unknown due to the accuracy of simulation models and the limited experimental data for comparison. Here we chose a small crowder of tetraethylene glycol (PEG-4) to investigate the self-crowding of PEG-4 solutions and molecular crowding effects on the structure and diffusion of lysozyme at varied concentrations from dilute water to pure PEG-4 liquid. Two Amber-like force fields of Amber14SB and a99SB- disp were examined with TIP3P (fast diffusivity and low viscosity) and a99SB- disp (slow diffusivity and high viscosity) water models, respectively. Compared to the Amber14SB protein simulations, the a99SB- disp model yields more coordinated water and less PEG-4 molecules, less intramolecular hydrogen bonds (HBs), more protein–water HBs, and less protein–PEG HBs as well as stronger interactions and more hydrophilic and less hydrophobic contacts with solvent molecules. The a99SB- disp model offers comparable protein–solvent interactions in concentrated PEG-4 solutions to that in pure water. The PEG-4 crowding leads to a slow-down in the diffusivity of water, PEG-4, and protein, and the decline in the diffusion from atomistic simulations is close to or faster than the hard sphere model that neglects attractive interactions. Despite these differences, the overall structure of lysozyme appears to be maintained well at different PEG-4 concentrations for both force fields, except a slightly large deviation at 370 K at low concentrations with the a99SB- disp model. This is mainly attributed to the strong intramolecular interactions of the protein in the Amber14SB force field and to the large viscosity of the a99SB- disp water model. The results indicate that the protein force fields and the viscosity of crowder solutions affect the simulation of biomolecules under crowding conditions.
Keywords	molecular crowding ; molecular dynamics simulation ; tetraethylene glycol ; protein diffusion ; Organic chemistry ; QD241-441
Subject code	541
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Molecular regulation of lipid metabolism in Suaeda salsa.

Yan, Bowei / Haiyang Zhang / Li, Huixin / Gao, Yuqiao / Wei, Yulei / Chang, Chuanyi / Zhang, Liguo / Li, Zuotong / Zhu, Lei / Xu, Jingyu

Plant physiology and biochemistry : PPB

2023 Volume 201, Page(s) 107894

Abstract: Suaeda salsa is remarkable for its high oil content and abundant unsaturated fatty acids. In this study, the regulatory networks on fatty acid and lipid metabolism were constructed by combining the de novo transcriptome and lipidome data. Differentially ... ...

Abstract	Suaeda salsa is remarkable for its high oil content and abundant unsaturated fatty acids. In this study, the regulatory networks on fatty acid and lipid metabolism were constructed by combining the de novo transcriptome and lipidome data. Differentially expressed genes (DEGs) associated with lipids biosynthesis pathways were identified in the S. salsa transcriptome. DEGs involved in fatty acid and glycerolipids were generally up-regulated in leaf tissues. DEGs for TAG assembly were enriched in developing seeds, while DEGs in phospholipid metabolic pathways were enriched in root tissues. Polar lipids were extracted from S. salsa tissues and analyzed by lipidomics. The proportion of galactolipid MGDG was the highest in S. salsa leaves. The molar percentage of PG was high in the developing seeds, and the other main phospholipids had higher molar percentage in roots of S. salsa. The predominant C36:6 molecular species indicates that S. salsa is a typical 18:3 plant. The combined transcriptomic and lipidomic data revealed that different tissues of S. salsa were featured with DEGs associated with specific lipid metabolic pathways, therefore, represented unique lipid profiles. This study will be helpful on understanding lipid metabolism pathway and exploring the key genes involved in lipid synthesis in S. salsa.
MeSH term(s)	Lipid Metabolism/genetics ; Gene Expression Profiling ; Transcriptome ; Chenopodiaceae/metabolism ; Fatty Acids/metabolism
Chemical Substances	Fatty Acids
Language	English
Publishing date	2023-07-13
Publishing country	France
Document type	Journal Article
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2023.107894
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Article ; Online: Repurposing Drugs for Inhibition against ALDH2 via a 2D/3D Ligand-Based Similarity Search and Molecular Simulation

Wanyun Jiang / Junzhao Chen / Puyu Zhang / Nannan Zheng / Le Ma / Yongguang Zhang / Haiyang Zhang

Molecules, Vol 28, Iss 21, p

2023 Volume 7325

Abstract: Aldehyde dehydrogenase-2 (ALDH2) is a crucial enzyme participating in intracellular aldehyde metabolism and is acknowledged as a potential therapeutic target for the treatment of alcohol use disorder and other addictive behaviors. Using previously ... ...

Abstract	Aldehyde dehydrogenase-2 (ALDH2) is a crucial enzyme participating in intracellular aldehyde metabolism and is acknowledged as a potential therapeutic target for the treatment of alcohol use disorder and other addictive behaviors. Using previously reported ALDH2 inhibitors of Daidzin, CVT-10216, and CHEMBL114083 as reference molecules, here we perform a ligand-based virtual screening of world-approved drugs via 2D/3D similarity search methods, followed by the assessments of molecular docking, toxicity prediction, molecular simulation, and the molecular mechanics Poisson–Boltzmann surface area (MM–PBSA) analysis. The 2D molecular fingerprinting of ECFP4 and FCFP4 and 3D molecule-shape-based USRCAT methods show good performances in selecting compounds with a strong binding behavior with ALDH2. Three compounds of Zeaxanthin ( q = 0), Troglitazone ( q = 0), and Sequinavir ( q = +1 e ) are singled out as potential inhibitors; Zeaxanthin can only be hit via USRCAT. These drugs displayed a stronger binding strength compared to the reported potent inhibitor CVT-10216. Sarizotan ( q = +1 e ) and Netarsudil ( q = 0/+1 e ) displayed a strong binding strength with ALDH2 as well, whereas they displayed a shallow penetration into the substrate-binding tunnel of ALDH2 and could not fully occupy it. This likely left a space for substrate binding, and thus they were not ideal inhibitors. The MM–PBSA results indicate that the selected negatively charged compounds from the similarity search and Vina scoring are thermodynamically unfavorable, mainly due to electrostatic repulsion with the receptor ( q = −6 e for ALDH2). The electrostatic attraction with positively charged compounds, however, yielded very strong binding results with ALDH2. These findings reveal a deficiency in the modeling of electrostatic interactions (in particular, between charged moieties) in the virtual screening via the 2D/3D similarity search and molecular docking with the Vina scoring system.
Keywords	drug repurposing ; ligand-based virtual screening ; substance use disorder ; receptor–ligand interactions ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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