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  1. AU="Halesh, L H"
  2. AU=Babajanyan S G
  3. AU="Haruhara, Kotaro"
  4. AU="Wang, Che-Wei"
  5. AU="Eisenberg, Marcia"
  6. AU="Ufnalska, Sylwia"
  7. AU="Leroux, Dominique"
  8. AU="Gallagher, Timothy J"
  9. AU=Baggish Aaron
  10. AU="Bush, Ashley I"
  11. AU="Carr, Kenneth D."
  12. AU="Spiro, Stephen"
  13. AU="Roberts, William Clifford"
  14. AU="Park, Hyungjong"
  15. AU="Das, Debasish"
  16. AU="Sanz-Magro, Adrián"
  17. AU="Fan, Shanhui"
  18. AU="Ellonen, Pekka"
  19. AU="Lambert, T"
  20. AU="Vivekanandan, Rajesh"

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  1. Artikel: Listeria monocytogenes meningitis: an uncommon opportunistic infection in HIV/AIDS.

    Patil, Asha B / Nadiger, Shobha / Chandrasekhar, M R / Halesh, L H / Kumar, Mahesh

    Indian journal of pathology & microbiology

    2007  Band 50, Heft 3, Seite(n) 671–673

    Abstract: Objective: To report an interesting case of meningitis caused by Listeria monocytogenes meningitis in an HIV seropositive individual.: Materials & methods: A previously healthy 45 years old HIV seropositive man, presented with atypical clinical ... ...

    Abstract Objective: To report an interesting case of meningitis caused by Listeria monocytogenes meningitis in an HIV seropositive individual.
    Materials & methods: A previously healthy 45 years old HIV seropositive man, presented with atypical clinical features of meningitis. Blood and Cerebrospinal fluid (CSF) were obtained for biochemical and microbiological investigations.
    Results: CSF analysis showed pleocytosis with lymphocytic predominance. Gram stain of CSF was negative; however culture yielded growth of gram positive bacilli with tumbling motility. Based on relevant biochemical tests the isolate was identified as Listeria monocytogenes. Patient was treated with i.v. ampicillin and recovered completely.
    Conclusion: Listeriosis is relatively rare in HIV/AIDS among the immunodeficient populations. Atypical clinical and laboratory findings make the diagnosis difficult and these infections may go undiagnosed. Since it is easily treated with readily available antibiotics, it is important to diagnose them at the earliest and thereby prevent treatment failure.
    Mesh-Begriff(e) AIDS-Related Opportunistic Infections/diagnosis ; AIDS-Related Opportunistic Infections/drug therapy ; AIDS-Related Opportunistic Infections/microbiology ; Ampicillin/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Culture Media ; HIV Infections/complications ; Humans ; Listeria monocytogenes/isolation & purification ; Male ; Meningitis, Listeria/diagnosis ; Meningitis, Listeria/drug therapy ; Meningitis, Listeria/microbiology ; Middle Aged ; Treatment Outcome
    Chemische Substanzen Anti-Bacterial Agents ; Culture Media ; Ampicillin (7C782967RD)
    Sprache Englisch
    Erscheinungsdatum 2007-07
    Erscheinungsland India
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 197621-7
    ISSN 0974-5130 ; 0377-4929
    ISSN (online) 0974-5130
    ISSN 0377-4929
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Detection and antifungal susceptibility testing of oral Candida dubliniensis from human immunodeficiency virus-infected patients.

    Chunchanur, Sneha K / Nadgir, Shobha D / Halesh, L H / Patil, B S / Kausar, Yasmeen / Chandrasekhar, M R

    Indian journal of pathology & microbiology

    2009  Band 52, Heft 4, Seite(n) 501–504

    Abstract: Context: Candida dubliniensis, an opportunistic yeast that has been implicated in oropharyngeal candidiasis (OPC) in patients infected with Human Immunodeficiency Virus (HIV) may be under-reported due to its similarity with Candida albicans. Resistance ... ...

    Abstract Context: Candida dubliniensis, an opportunistic yeast that has been implicated in oropharyngeal candidiasis (OPC) in patients infected with Human Immunodeficiency Virus (HIV) may be under-reported due to its similarity with Candida albicans. Resistance to Fluconazole is often seen in C. dubliniensis isolates from clinical specimens.
    Aims: To know the prevalence of C. dubliniensis in OPC in patients infected with HIV and their antifungal susceptibility pattern.
    Settings and design: One hundred and thirty-two HIV seropositive individuals and 50 healthy controls were included in the study.
    Materials and methods: Two oral swabs were collected from the site of the lesion from 132 HIV-infected patients. Oral rinse was obtained from 50 healthy controls. Samples were inoculated on Sabouraud's dextrose agar (SDA) medium and on HiCrome Candida Differential Agar (CHROM agar) medium. Isolates were speciated by standard tests. Dark green-colored, germ tube positive isolates, which failed to grow at 420C and negative for xylose assimilation were identified as C. dubliniensis. Antifungal susceptibility test was performed by Macro broth dilution technique (National Committee for Clinical Laboratory Standards guidelines).
    Results and conclusions: From 132 patients, 22 (16.3%) C. dubliniensis were isolated; samples from healthy controls did not reveal their presence. Antifungal susceptibility test showed higher resistance among C. dubliniensis isolates to azoles compared to C. albicans. Five (22.7%) isolates of C. dubliniensis were resistant to Fluconazole followed by four (18.2%) to Ketoconazole. This study emphasizes the importance of identification and antifungal susceptibility testing of C. dubliniensis in HIV-infected patients.
    Mesh-Begriff(e) Antifungal Agents/pharmacology ; Azoles/pharmacology ; Candida/drug effects ; Candida/isolation & purification ; Candidiasis/epidemiology ; Candidiasis/microbiology ; Drug Resistance, Fungal ; HIV Infections/complications ; Humans ; Microbial Sensitivity Tests ; Mouth/microbiology ; Prevalence
    Chemische Substanzen Antifungal Agents ; Azoles
    Sprache Englisch
    Erscheinungsdatum 2009-10
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 197621-7
    ISSN 0974-5130 ; 0377-4929
    ISSN (online) 0974-5130
    ISSN 0377-4929
    DOI 10.4103/0377-4929.56138
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Significance of isolation and drug susceptibility testing of non-Candida albicans species causing oropharyngeal candidiasis in HIV patients.

    Nadagir, Shobha D / Chunchanur, Sneha K / Halesh, L H / Yasmeen, K / Chandrasekhar, M R / Patil, B S

    The Southeast Asian journal of tropical medicine and public health

    2008  Band 39, Heft 3, Seite(n) 492–495

    Abstract: Oropharyngeal candidiasis (OPC) continues to be a common opportunistic infection in patients infected with Human Immunodeficiency Virus (HIV) and is predictive of increasing immunosuppression. Though Candida albicans remains the predominant isolate, a ... ...

    Abstract Oropharyngeal candidiasis (OPC) continues to be a common opportunistic infection in patients infected with Human Immunodeficiency Virus (HIV) and is predictive of increasing immunosuppression. Though Candida albicans remains the predominant isolate, a rise in the frequency of isolation of non-albicans Candida (NAC) species is being observed. The levels of virulence and the sensitivities to available antifungal drugs vary among these species. Of 340 HIV seropositive patients in this study, 132 (38.8%) had oral lesions suggestive of candidiasis. Samples were collected from the lesion using sterile cotton swabs. Isolation and speciation were done by standard techniques. Antifungal drug susceptibility testing was done by macro broth dilution. The total number of Candida isolates was 135, of which, 45 (33.3%) were NAC species and 90 were C.albicans (66.6%). Of the NAC species, C. dubliniensis was the predominant pathogen (22,48.9%). Antifungal susceptibility testing showed that 14 (31.1%) of the NAC species and 11 (12.2%) of C. albicans were resistant to fluconazole (MIC > 8 microg/ml). A very high MIC of > 32 microg/ml was noted among the NAC species resistant to fluconazole.
    Mesh-Begriff(e) AIDS-Related Opportunistic Infections/microbiology ; Antifungal Agents/pharmacology ; Candida/drug effects ; Candida/isolation & purification ; Candidiasis, Oral/microbiology ; Candidiasis, Oral/virology ; Drug Resistance, Fungal ; Fluconazole/pharmacology ; HIV Infections/microbiology ; Humans ; Ketoconazole/pharmacology ; Microbial Sensitivity Tests
    Chemische Substanzen Antifungal Agents ; Fluconazole (8VZV102JFY) ; Ketoconazole (R9400W927I)
    Sprache Englisch
    Erscheinungsdatum 2008-05
    Erscheinungsland Thailand
    Dokumenttyp Journal Article
    ZDB-ID 800646-5
    ISSN 0125-1562 ; 0038-3619
    ISSN 0125-1562 ; 0038-3619
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Subconjunctival dirofilariasis in India.

    Nadgir, S / Tallur, S S / Mangoli, V / Halesh, L H / Krishna, B V

    The Southeast Asian journal of tropical medicine and public health

    2001  Band 32, Heft 2, Seite(n) 244–246

    Abstract: Human dirofilariasis caused by Dirofilaria repens, have been reported to occur widely throughout Asia, Europe and Africa. Reports of this infection from India are however limited. Herein we report a case of subconjunctival dirofilariasis from Karnataka ... ...

    Abstract Human dirofilariasis caused by Dirofilaria repens, have been reported to occur widely throughout Asia, Europe and Africa. Reports of this infection from India are however limited. Herein we report a case of subconjunctival dirofilariasis from Karnataka state of India. A 42 year old man presented with a history of pain and swelling in the left eye. A live parasite measuring 3.5cm in length was surgically removed from the nodular swelling in the conjunctiva. The parasite was identified as Dirofilaria repens, adult male.
    Mesh-Begriff(e) Adult ; Animals ; Conjunctival Diseases/epidemiology ; Conjunctival Diseases/parasitology ; Conjunctival Diseases/surgery ; Dirofilariasis/epidemiology ; Dirofilariasis/surgery ; Humans ; India/epidemiology ; Male
    Sprache Englisch
    Erscheinungsdatum 2001-06
    Erscheinungsland Thailand
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 800646-5
    ISSN 0125-1562 ; 0038-3619
    ISSN 0125-1562 ; 0038-3619
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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