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  1. Article ; Online: Medial-lateral organization of primary auditory cortex and the question of sound localization.

    Hallett, Mark

    The Journal of comparative neurology

    2023  Volume 531, Issue 18, Page(s) 1893–1896

    Abstract: Pandya made many important contributions to the understanding of the anatomy of the cortical auditory pathways beginning with his publication in 1969. This review focuses on the observation in that article on the transcallosal connections of the primary ... ...

    Abstract Pandya made many important contributions to the understanding of the anatomy of the cortical auditory pathways beginning with his publication in 1969. This review focuses on the observation in that article on the transcallosal connections of the primary auditory cortex. The medial part of the cortex has such connections, but the lateral part does not. Pandya and colleagues speculated that this might have something to do with spatial localization of sound. Review of the subsequent literature shows that the primary auditory cortex anatomy is complex, but the original observation is likely correct. However, the physiological speculation was not.
    MeSH term(s) Sound Localization/physiology ; Auditory Cortex/anatomy & histology ; Acoustic Stimulation ; Auditory Pathways/physiology ; Brain Mapping
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Intramural
    ZDB-ID 3086-7
    ISSN 1096-9861 ; 0021-9967 ; 0092-7317
    ISSN (online) 1096-9861
    ISSN 0021-9967 ; 0092-7317
    DOI 10.1002/cne.25516
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  2. Article ; Online: Transcranial Pulse Stimulation (TPS) - A highly focused brain stimulation therapy with 3D navigation.

    Beisteiner, R / Hallett, M

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    2022  Volume 136, Page(s) 247–248

    MeSH term(s) Brain ; Humans ; Stereotaxic Techniques ; Transcranial Direct Current Stimulation
    Language English
    Publishing date 2022-01-31
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1463630-x
    ISSN 1872-8952 ; 0921-884X ; 1388-2457
    ISSN (online) 1872-8952
    ISSN 0921-884X ; 1388-2457
    DOI 10.1016/j.clinph.2022.01.127
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  3. Article: Neurophysiologic studies of functional neurologic disorders.

    Hallett, M

    Handbook of clinical neurology

    2016  Volume 139, Page(s) 61–71

    Abstract: Functional neurologic disorders are largely genuine and represent conversion disorders, where the dysfunction is unconscious, but there are some that are factitious, where the abnormality is feigned and conscious. Malingering, which can have the same ... ...

    Abstract Functional neurologic disorders are largely genuine and represent conversion disorders, where the dysfunction is unconscious, but there are some that are factitious, where the abnormality is feigned and conscious. Malingering, which can have the same manifestations, is similarly feigned, but not considered a genuine disease. There are no good methods for differentiating these three entities at the present time. Physiologic studies of functional weakness and sensory loss reveal normal functioning of primary motor and sensory cortex, but abnormalities of premotor cortex and association cortices. This suggests a top-down influence creating the dysfunction. Studies of functional tremor and myoclonus show that these disorders utilize normal voluntary motor structures to produce the involuntary movements, again suggesting a higher-level abnormality. Agency is abnormal and studies shows that dysfunction of the temporoparietal junction may be a correlate. The limbic system is overactive and might initiate involuntary movements, but the mechanism for this is not known. The limbic system would then be the source of top-down dysfunction. It can be speculated that the involuntary movements are involuntary due to lack of proper feedforward signaling.
    MeSH term(s) Conversion Disorder/diagnosis ; Factitious Disorders/diagnosis ; Humans ; Malingering/diagnosis ; Nervous System Diseases/diagnosis ; Nervous System Diseases/psychology ; Neurophysiology/methods
    Language English
    Publishing date 2016-09-27
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-12-801772-2.00006-0
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  4. Article ; Online: The dystonias: a heterogeneous collection.

    Hallett, M

    European journal of neurology

    2015  Volume 22, Issue 5, Page(s) 741–742

    MeSH term(s) Blinking/physiology ; Cerebellar Diseases/physiopathology ; Conditioning (Psychology)/physiology ; Dystonia Musculorum Deformans/physiopathology ; Female ; Humans ; Male
    Language English
    Publishing date 2015-05
    Publishing country England
    Document type Comment ; Editorial ; Research Support, N.I.H., Intramural
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.12526
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  5. Article ; Online: Functional movement disorders: Is the crisis resolved?

    Hallett, Mark

    Movement disorders : official journal of the Movement Disorder Society

    2019  Volume 34, Issue 7, Page(s) 971–974

    MeSH term(s) Brain/physiopathology ; Humans ; Movement/physiology ; Movement Disorders/diagnosis ; Movement Disorders/physiopathology ; Prognosis ; Research
    Language English
    Publishing date 2019-05-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.27713
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  6. Book ; Conference proceedings: Advances in clinical neurophysiology

    Hallett, Mark

    proceedings of the 27th International Congress of Clinical Neurophysiology, AAEM 50th anniversary and 57th annual meeting of the ACNS joint meeting, San Francisco, CA, USA, 15 - 20 September 2003

    (Clinical neurophysiology : Supplement ; 57)

    2004  

    Institution American Association of Electrodiagnostic Medicine
    American Clinical Neurophysiology Society
    Event/congress International Congress of Clinical Neurophysiology (27, 2003, SanFranciscoCalif.)
    Author's details ed. by M. Hallett
    Series title Clinical neurophysiology : Supplement ; 57
    Clinical neurophysiology
    Clinical neurophysiology ; Supplement
    Collection Clinical neurophysiology
    Clinical neurophysiology ; Supplement
    Language English
    Size XXI, 760 S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT014402241
    ISBN 0-444-51439-2 ; 978-0-444-51439-4
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Reappraisal of cortical myoclonus: Electrophysiology is the gold standard.

    Hallett, Mark

    Movement disorders : official journal of the Movement Disorder Society

    2018  Volume 33, Issue 7, Page(s) 1190

    MeSH term(s) Electroencephalography ; Electrophysiology ; Humans ; Myoclonus ; Neurophysiology ; Retrospective Studies
    Language English
    Publishing date 2018-09-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.27430
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  8. Article: The rise of movement disorders.

    Hallett, Mark

    Neurology India

    2018  Volume 66, Issue Supplement, Page(s) S10–S11

    MeSH term(s) Humans ; Movement Disorders/diagnosis ; Movement Disorders/therapy
    Language English
    Publishing date 2018-03-13
    Publishing country India
    Document type Editorial
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.226445
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  9. Article ; Online: Patients with Parkinson disease are prone to functional neurological disorders.

    Hallett, Mark

    Journal of neurology, neurosurgery, and psychiatry

    2018  Volume 89, Issue 6, Page(s) 557

    MeSH term(s) Humans ; Nervous System Diseases ; Parkinson Disease ; REM Sleep Behavior Disorder
    Language English
    Publishing date 2018-03-16
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Intramural ; Comment
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp-2017-317684
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  10. Article ; Online: Refining the clinical diagnosis of Parkinson's disease.

    Mulroy, Eoin / Erro, Roberto / Bhatia, Kailash P / Hallett, Mark

    Parkinsonism & related disorders

    2024  , Page(s) 106041

    Abstract: Our ability to define, understand, and classify Parkinson's disease (PD) has undergone significant changes since the disorder was first described in 1817. Clinical features and neuropathologic signatures can now be supplemented by in-vivo interrogation ... ...

    Abstract Our ability to define, understand, and classify Parkinson's disease (PD) has undergone significant changes since the disorder was first described in 1817. Clinical features and neuropathologic signatures can now be supplemented by in-vivo interrogation of genetic and biological substrates of disease, offering great opportunity for further refining the diagnosis of PD. In this mini-review, we discuss the historical perspectives which shaped our thinking surrounding the definition and diagnosis of PD. We highlight the clinical, genetic, pathologic and biologic diversity which underpins the condition, and proceed to discuss how recent developments in our ability to define biologic and pathologic substrates of disease might impact PD definition, diagnosis, individualised prognostication, and personalised clinical care. We argue that Parkinson's 'disease', as currently diagnosed in the clinic, is actually a syndrome. It is the outward manifestation of any array of potential dysfunctional biologic processes, neuropathological changes, and disease aetiologies, which culminate in common outward clinical features which we term PD; each person has their own unique disease, which we can now define with increasing precision. This is an exciting time in PD research and clinical care. Our ability to refine the clinical diagnosis of PD, incorporating in-vivo assessments of disease biology, neuropathology, and neurogenetics may well herald the era of biologically-based, precision medicine approaches PD management. With this however comes a number of challenges, including how to integrate these technologies into clinical practice in a way which is acceptable to patients, promotes meaningful changes to care, and minimises health economic impact.
    Language English
    Publishing date 2024-02-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1311489-x
    ISSN 1873-5126 ; 1353-8020
    ISSN (online) 1873-5126
    ISSN 1353-8020
    DOI 10.1016/j.parkreldis.2024.106041
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