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  1. Article ; Online: Fabrication for single/few-mode Y-branch waveguide using the Mosquito method.

    Hatai, Ryosuke / Hama, Hiroki / Ishigure, Takaaki

    Optics express

    2022  Volume 30, Issue 3, Page(s) 3524–3537

    Abstract: In this paper, Y-branched circular core single-mode/few-mode polymer optical waveguides are designed and fabricated using the Mosquito method we have developed. They comprise a low loss multiplexing (MUX) device for mode division multiplexing. In the ... ...

    Abstract In this paper, Y-branched circular core single-mode/few-mode polymer optical waveguides are designed and fabricated using the Mosquito method we have developed. They comprise a low loss multiplexing (MUX) device for mode division multiplexing. In the Mosquito method, since a liquid core monomer is dispensed into another liquid cladding monomer while the needle scans along the path of the wiring patterns, it was difficult to form in-plane core crossings and core branches. In this paper, to form single-mode/few-mode Y-branched cores, we apply a unicursal needle-scan path for the Y-branch structure with the Mosquito method. For MUX device applications, cores satisfying the single-mode condition are successfully formed on the two-port side while the one-port side has a few-mode core.
    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.447313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Delayed recognition of autism spectrum disorder and attention-deficit/hyperactivity disorder in a girl with ornithine transcarbamylase deficiency: A case report.

    Kadono, Shin / Miyawaki, Dai / Goto, Ayako / Hirai, Kaoru / Sakamoto, Shoko / Hama, Hiroki / Nishiura, Sayaka / Hamazaki, Takashi / Inoue, Koki

    Medicine

    2023  Volume 102, Issue 8, Page(s) e33055

    Abstract: Rationale: Ornithine transcarbamylase (OTC) deficiency, a urea cycle disorder, is a rare congenital metabolic error that leads to hyperammonemia. Psychiatric symptoms of hyperammonemia are nonspecific and can cause autism spectrum disorder (ASD)-like ... ...

    Abstract Rationale: Ornithine transcarbamylase (OTC) deficiency, a urea cycle disorder, is a rare congenital metabolic error that leads to hyperammonemia. Psychiatric symptoms of hyperammonemia are nonspecific and can cause autism spectrum disorder (ASD)-like symptoms and attention-deficit/hyperactivity disorder (ADHD)-like symptoms. Some studies report that OTC deficiency is often initially diagnosed as ASD or ADHD. However, there are no reports of OTC deficiency comorbid with ASD and ADHD.
    Patient concerns: The patient is 17-year-old girl diagnosed with OTC deficiency at 3 years of age. She had behavioral problems since childhood, including depressed mood, irritability, and impulsive behavior; however, they were considered OTC-mediated nonspecific psychiatric symptoms. Therefore, the patient had not been appropriately assessed for ASD and ADHD. She presented with depressed mood and self-harm at 17 years of age.
    Diagnoses: We diagnosed her with ASD and ADHD based on her medical history and semistructured interviews.
    Interventions: We focused her ASD and ADHD traits and discussed strategies with her for better adaptive living.
    Outcomes: Our interventions resulted in her better social adjustment.
    Lessons: Physicians should consider the possibility of comorbid ASD and ADHD in individuals with OTC, facilitating appropriate and intervention for better outcomes.
    MeSH term(s) Humans ; Female ; Child ; Adolescent ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Ornithine Carbamoyltransferase Deficiency Disease ; Autism Spectrum Disorder/epidemiology ; Hyperammonemia ; Comorbidity
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000033055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Associations Between Internet Addiction, Psychiatric Comorbidity, and Maternal Depression and Anxiety: Potential Underlying Mechanisms [Response to Letter].

    Sakamoto, Shoko / Miyawaki, Dai / Goto, Ayako / Hirai, Kaoru / Hama, Hiroki / Kadono, Shin / Nishiura, Sayaka / Inoue, Koki

    Neuropsychiatric disease and treatment

    2023  Volume 19, Page(s) 949–950

    Language English
    Publishing date 2023-04-18
    Publishing country New Zealand
    Document type Journal Article ; Comment
    ZDB-ID 2186503-6
    ISSN 1178-2021 ; 1176-6328
    ISSN (online) 1178-2021
    ISSN 1176-6328
    DOI 10.2147/NDT.S415170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Associations Between Chronic Irritability and Sensory Processing Difficulties in Children and Adolescents.

    Harima, Yuji / Miyawaki, Dai / Goto, Ayako / Hirai, Kaoru / Sakamoto, Shoko / Hama, Hiroki / Kadono, Shin / Nishiura, Sayaka / Inoue, Koki

    Frontiers in psychiatry

    2022  Volume 13, Page(s) 860278

    Abstract: Irritability is one of the most common reasons for which children and adolescents are referred for psychiatric evaluation and care. However, clinical irritability is difficult to define; thus, its prevalence varies widely. Chronic irritability may be ... ...

    Abstract Irritability is one of the most common reasons for which children and adolescents are referred for psychiatric evaluation and care. However, clinical irritability is difficult to define; thus, its prevalence varies widely. Chronic irritability may be associated with sensory processing difficulties (SPD), but little is known about the relationship between these two factors in clinical populations. In this study, we examined the prevalence of chronic irritability and its association with SPD in 166 children aged 5-16 years who were referred to the psychiatric outpatient clinic of the Osaka City University Hospital. Chronic irritability and parent-reported scores for the Short Sensory Profile, Infant Behavior Checklist-Revised, Child Behavior Checklist, and Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children (Present and Lifetime version) questionnaires were used for assessment. A total of 22 children (13.2%) presented with chronic irritability (i.e., the irritability group) and were more likely to have oppositional defiant disorder, externalizing problems, and attention issues than those without chronic irritability (i.e., the control group). SPD were reported in eight (36%) patients in the irritability group and in 21 (15%) in the control group (
    Language English
    Publishing date 2022-04-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2022.860278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Associations between Internet Addiction, Psychiatric Comorbidity, and Maternal Depression and Anxiety in Clinically Referred Children and Adolescents.

    Sakamoto, Shoko / Miyawaki, Dai / Goto, Ayako / Hirai, Kaoru / Hama, Hiroki / Kadono, Shin / Nishiura, Sayaka / Inoue, Koki

    Neuropsychiatric disease and treatment

    2022  Volume 18, Page(s) 2421–2430

    Abstract: Purpose: Internet addiction (IA) has become a global problem and is one of the most common reasons for children to be referred for intervention because IA results in social and educational dysfunction and conflict with parents. IA is associated with ... ...

    Abstract Purpose: Internet addiction (IA) has become a global problem and is one of the most common reasons for children to be referred for intervention because IA results in social and educational dysfunction and conflict with parents. IA is associated with various comorbid psychiatric disorders, with notable association between IA and family factors. However, little is known about parental psychopathology. This study aimed to examine the prevalence of IA and association between IA and maternal depression and anxiety in clinical samples after adjusting for comorbidities.
    Patients and methods: A cross-sectional study was conducted between April 2020 and August 2021 at the Department of Neuropsychiatry of Osaka Metropolitan University Hospital in Japan. A total of 218 clinically referred children and adolescents (aged 8 to 15 years) were assessed using the Internet Addiction Test, which is one of the most popular questionnaires to evaluate IA, the Child Behavior Checklist (CBCL), and The Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version. IA was defined as a total score on the Internet Addiction Test ≥ 50. Of those, for the evaluation of maternal depression and anxiety, the 132 mothers of the children who were referred after January 2021 completed K6 as well.
    Results: A total of 68 participants (31.2%) presented with IA and had higher total and externalizing scores of CBCL, social anxiety disorder, and oppositional defiant disorder compared to those without IA. IA was associated with the six-item Kessler scale scores of mothers, being raised by single parents, and anxiety disorders after adjusting for age, sex, and family income (95% CI: 1.023-1.215).
    Conclusion: Maternal depression and anxiety may be one of the risk factors for children and adolescents to develop IA. Care for maternal depression and anxiety may contribute to intervention for children and adolescents with IA.
    Language English
    Publishing date 2022-10-21
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186503-6
    ISSN 1178-2021 ; 1176-6328
    ISSN (online) 1178-2021
    ISSN 1176-6328
    DOI 10.2147/NDT.S383160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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