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  1. Article: Diffuse large B cell gastric lymphoma a rare disease: the effort to obtain scientific data in a multicenter, multinational retrospective trial.

    Hamerschlak, Nelson

    Revista brasileira de hematologia e hemoterapia

    2016  Volume 38, Issue 3, Page(s) 186–187

    Language English
    Publishing date 2016-06-23
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2105177-X
    ISSN 1806-0870 ; 1516-8484
    ISSN (online) 1806-0870
    ISSN 1516-8484
    DOI 10.1016/j.bjhh.2016.05.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Haploidentical transplantation of hematopoietic stem cells.

    Hamerschlak, Nelson

    Revista da Associacao Medica Brasileira (1992)

    2016  Volume 62 Suppl 1, Page(s) 29–33

    Abstract: Objective: To review and discuss the literature on hematopoietic stem cell transplantation (HSCT) with haploidentical donors in Brazil.: Method: Literature review.: Results: The haploidentical hematopoietic stem cell transplantations have become a ...

    Abstract Objective: To review and discuss the literature on hematopoietic stem cell transplantation (HSCT) with haploidentical donors in Brazil.
    Method: Literature review.
    Results: The haploidentical hematopoietic stem cell transplantations have become a safe option in hematology since the 80s, with the possibility of ex-vivo T-cell depletion. However, its broad use worldwide occurred with the advent of haploidentical nonmyeloablative transplants using in vivo T-cell depletion with the administration of post-transplant cyclophosphamide. The results were encouraging, despite the increased risk of infection and post-transplantation recurrence. Recent publications on acute myeloid leukemia, myelodysplastic syndrome and Hodgkin's lymphoma have shown similar results among haploidentical, unrelated and related full-match transplants. Obviously, these findings of retrospective studies should be confirmed by clinical trials.
    Conclusions: Transplantation with haploidentical donor has shown to be feasible in Brazil and the first publications and results are showing encouraging results.
    MeSH term(s) Brazil ; Donor Selection/methods ; Hematopoietic Stem Cell Transplantation/methods ; Hematopoietic Stem Cell Transplantation/mortality ; Histocompatibility ; Humans ; Risk Assessment ; Time Factors ; Tissue Donors ; Treatment Outcome
    Language English
    Publishing date 2016-10
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1590/1806-9282.62.suppl1.29
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Fine and Gray or Cox model?

    Arcuri, Leonardo Javier / Souza Santos, Fabio Pires de / Perini, Guilherme Fleury / Hamerschlak, Nelson

    Blood advances

    2024  Volume 8, Issue 6, Page(s) 1420–1421

    MeSH term(s) Proportional Hazards Models ; Risk Factors ; Risk Assessment
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2915908-8
    ISSN 2473-9537 ; 2473-9529
    ISSN (online) 2473-9537
    ISSN 2473-9529
    DOI 10.1182/bloodadvances.2023012157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: 50 years of BMT: risk stratification, donor matching and stem cell collection for transplantation.

    Hamerschlak, Nelson / Gómez-Almaguer, David / McLornan, Donal P

    Frontiers in oncology

    2023  Volume 13, Page(s) 1321334

    Language English
    Publishing date 2023-12-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1321334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Posttransplant cyclophosphamide beyond haploidentical transplantation.

    Arcuri, Leonardo Javier / Ribeiro, Andreza Alice Feitosa / Hamerschlak, Nelson / Kerbauy, Mariana Nassif

    Annals of hematology

    2023  Volume 103, Issue 5, Page(s) 1483–1491

    Abstract: Posttransplant cyclophosphamide (PTCy) has practically revolutionized haploidentical (Haplo) hematopoietic cell transplantation (HCT). Comparisons between Haplo with PTCy and unrelated donor (URD) with conventional graft-versus-host disease (GVHD) ... ...

    Abstract Posttransplant cyclophosphamide (PTCy) has practically revolutionized haploidentical (Haplo) hematopoietic cell transplantation (HCT). Comparisons between Haplo with PTCy and unrelated donor (URD) with conventional graft-versus-host disease (GVHD) prophylaxis have shown comparable overall survival with lower incidences of GVHD with Haplo/PTCy and led to the following question: is it PTCy so good that can be successfully incorporated into matched related donor (MRD) and URD HCT? In this review, we discuss other ways of doing PTCy, PTCy in peripheral blood haploidentical transplants, PTCy in the context of matched related and matched unrelated donors, PTCy with mismatched unrelated donors, and PTCy following checkpoint inhibitor treatment. PTCy is emerging as a new standard GVHD prophylaxis in haploidentical, HLA-matched, and -mismatched HCT.
    MeSH term(s) Humans ; Transplantation, Haploidentical ; Cyclophosphamide/therapeutic use ; Hematopoietic Stem Cell Transplantation ; Graft vs Host Disease/etiology ; Graft vs Host Disease/prevention & control ; Graft vs Host Disease/drug therapy ; Unrelated Donors ; Retrospective Studies
    Chemical Substances Cyclophosphamide (8N3DW7272P)
    Language English
    Publishing date 2023-06-01
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1064950-5
    ISSN 1432-0584 ; 0939-5555 ; 0945-8077
    ISSN (online) 1432-0584
    ISSN 0939-5555 ; 0945-8077
    DOI 10.1007/s00277-023-05300-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Improving patient access to modern myeloma therapy in Latin America: first step, know what your problem really is.

    Hamerschlak, Nelson / de Lima, Marcos

    Leukemia & lymphoma

    2020  Volume 61, Issue 13, Page(s) 3033–3034

    MeSH term(s) Humans ; Latin America/epidemiology ; Multiple Myeloma/diagnosis ; Multiple Myeloma/drug therapy ; Multiple Myeloma/epidemiology
    Language English
    Publishing date 2020-09-24
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2020.1821013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Myeloid leukemia: are we getting better?

    Hamerschlak, Nelson

    Revista brasileira de hematologia e hemoterapia

    2014  Volume 37, Issue 1, Page(s) 3–4

    Language English
    Publishing date 2014-11-21
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2105177-X
    ISSN 1806-0870 ; 1516-8484
    ISSN (online) 1806-0870
    ISSN 1516-8484
    DOI 10.1016/j.bjhh.2014.11.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Correcting an unintentional injustice: a comment on the doctorate thesis 'Transfusion' by José Carvalho Tolentino presented in 1878.

    Hamerschlak, Nelson

    Revista brasileira de hematologia e hemoterapia

    2014  Volume 36, Issue 4, Page(s) 302–304

    Language English
    Publishing date 2014-05-29
    Publishing country Brazil
    Document type Letter
    ZDB-ID 2105177-X
    ISSN 1806-0870 ; 1516-8484
    ISSN (online) 1806-0870
    ISSN 1516-8484
    DOI 10.1016/j.bjhh.2014.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Total marrow irradiation in hematopoietic stem cell transplantation for hematologic malignancies.

    Kerbauy, Mariana Nassif / Arcuri, Leonardo Javier / Favareto, Sergio Leonardo / de Rezende, Ana Carolina Pires / Hamerschlak, Nelson

    Frontiers in medicine

    2023  Volume 10, Page(s) 1155954

    Abstract: Total body irradiation (TBI) has been an essential component of the conditioning regimen in hematopoietic cell transplantation for many years. However, higher doses of TBI reduce disease relapse at the expense of more significant toxicities. Therefore, ... ...

    Abstract Total body irradiation (TBI) has been an essential component of the conditioning regimen in hematopoietic cell transplantation for many years. However, higher doses of TBI reduce disease relapse at the expense of more significant toxicities. Therefore, total marrow irradiation and total marrow and lymphoid irradiation have been developed to deliver organ-sparing targeted radiotherapy. Data from different studies show that TMI and TMLI can be safely administered in escalating doses in association with different chemotherapy conditioning regimen protocols, in situations with unmet needs, such as multiple myeloma, high-risk hematologic malignancies, relapsed or refractory leukemias, and elderly or frail patients, with low rates of transplant-related mortality. We reviewed the literature on applying TMI and TMLI techniques in autologous and allogeneic hematopoietic stem cell transplantation in different clinical situations.
    Language English
    Publishing date 2023-04-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1155954
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Let us think about lymphocyte counts!

    Hamerschlak, Nelson

    Revista brasileira de hematologia e hemoterapia

    2012  Volume 34, Issue 6, Page(s) 407

    Language English
    Publishing date 2012-12-26
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2105177-X
    ISSN 1806-0870 ; 1516-8484
    ISSN (online) 1806-0870
    ISSN 1516-8484
    DOI 10.5581/1516-8484.20120100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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