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  1. Book: Immediate Implant Placement and Loading – Single or Multiple Teeth Requiring Replacement

    Lambert, France / Wismeijer, Daniel / Barter, Stephen / Donos, Nikolaos / Hamilton, Adam

    (ITI Treatment Guide Series (Engl.) ; 14)

    2023  

    Abstract: Dental implants are used routinely throughout the world to replace missing teeth. With the broadening of treatment options and an increasing number of clinicians that provide implant therapy, it is important to ensure that the treatment methods used meet ...

    Author's details Professor Nikos Donos is the Chair of Periodontology & Implant Dentistry, the Director of Clinical Research, the Head of the Centre for Oral Clinical Research and the Lead for the Centre of Oral Immunobiology & Regenerative Medicine at the Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London (QMUL). Prof. Donos is also the Director of the ITI scholarship Centre and the Director of the Osteology Research Scholarship Centre, both at QMUL. In 2009, Professor Donos has been awarded the title of Honorary Professor at the Faculty of Dentistry in Hong Kong, in 2012 the title of Adjunct Professor at the Dental School, Griffith University in Australia, in 2015 the title of Honorary Professor at UCL-Eastman Dental Institute and in 2019 the title of Honorary Professor, School of Dentistry, University of Queensland, Australia. In 2011, Professor Donos was awarded the prestigious International Association for Dental Research (IADR)-Periodon
    Series title ITI Treatment Guide Series (Engl.) ; 14
    Abstract Dental implants are used routinely throughout the world to replace missing teeth. With the broadening of treatment options and an increasing number of clinicians that provide implant therapy, it is important to ensure that the treatment methods used meet the highest clinical standards. -- -- The ITI Treatment Guide series is a compendium of evidence-based implant-therapy techniques in daily practice. Written by renowned clinicians and supported by contributors from expert practitioners, the ...
    Keywords Implantology ; Implants ; dental implants ; ITI ; iti team ; Treatment Guide ; ITI 14 ; ITI TG 14 ; immediate implant placement ; implant placement ; immediate implant ; immediate loading protocols ; loading protocols ; immediate loading ; tooth extraction
    Language English
    Size 288 p.
    Edition 1
    Publisher Quintessence Publishing Co. Ltd
    Document type Book
    Note PDA Manuell_23
    Format 210 x 280
    ISBN 9781786981271 ; 1786981270
    Database PDA

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  2. Article ; Online: Traumatic spinal cord injury and the contributions of the post-injury microbiome.

    Hamilton, Adam M / Sampson, Timothy R

    International review of neurobiology

    2022  Volume 167, Page(s) 251–290

    Abstract: Spinal cord injuries are an enormous burden on injured individuals and their caregivers. The pathophysiological effects of injury are not limited to the spine and limb function, but affect numerous body systems. Growing observations in human studies and ... ...

    Abstract Spinal cord injuries are an enormous burden on injured individuals and their caregivers. The pathophysiological effects of injury are not limited to the spine and limb function, but affect numerous body systems. Growing observations in human studies and experimental models suggest that the gut microbiome is altered following spinal cord injury. Given the importance of signals derived from the gut microbiome for host physiology, it is possible that injury-triggered dysbiosis subsequently affects aspects of recovery. Here, we review emerging literature on the role of the microbiome following spinal cord injury. Specifically, we highlight findings from both human and experimental studies that correlate taxonomic changes to aspects of injury recovery. Examination of both observational and emerging interventional studies supports the notion that future therapeutic avenues for spinal cord injury pathologies may lie at the interface of the host and indigenous microbes.
    MeSH term(s) Humans ; Spinal Cord Injuries/pathology ; Gastrointestinal Microbiome
    Language English
    Publishing date 2022-07-14
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 209876-3
    ISSN 2162-5514 ; 0074-7742
    ISSN (online) 2162-5514
    ISSN 0074-7742
    DOI 10.1016/bs.irn.2022.06.003
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  3. Article ; Online: The relationship between cognitive reserve and the spontaneous use of emotion regulation strategies in older adults: a cross-sectional study.

    Colombo, Barbara / Hamilton, Adam / Telazzi, Ilaria / Balzarotti, Stefania

    Aging clinical and experimental research

    2023  Volume 35, Issue 7, Page(s) 1505–1512

    Abstract: Background: Several studies reported cognitive reserve (CR) as an important factor in promoting healthy aging within a non-clinical aging population.: Aims: The main goal of the present study is to investigate the link between higher levels of CR and ...

    Abstract Background: Several studies reported cognitive reserve (CR) as an important factor in promoting healthy aging within a non-clinical aging population.
    Aims: The main goal of the present study is to investigate the link between higher levels of CR and more effective emotion regulation. In more detail, we examine the association between a number of CR proxies and the habitual use of two emotion regulation strategies, cognitive reappraisal and emotional suppression.
    Methods: Three hundred and ten older adults aged between 60 and 75 (mean = 64.45, SD = 4.37; 69.4% female) joined this cross-sectional study by filling out self-report measures of CR and emotion regulation.² RESULTS: Reappraisal and suppression use were correlated. Practicing different leisure activities constantly over many years, being more original and having a higher education promoted more frequent use of cognitive reappraisal. These CR proxies were also significantly related to suppression use, even though the percentage of variance explained was lower.
    Discussion and conclusions: Exploring the role played by the cognitive reserve on different emotion regulation techniques can be useful in understanding which variables predict the use of antecedent-focused (reappraisal) or response-focused (suppression) emotion regulation strategies in aging individuals.
    MeSH term(s) Humans ; Female ; Aged ; Male ; Cognitive Reserve/physiology ; Cross-Sectional Studies ; Emotional Regulation ; Emotions/physiology ; Aging/psychology
    Language English
    Publishing date 2023-05-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2104785-6
    ISSN 1720-8319 ; 1594-0667
    ISSN (online) 1720-8319
    ISSN 1594-0667
    DOI 10.1007/s40520-023-02424-9
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    Zs.A 3343: Show issues Location:
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  4. Article ; Online: The Anatomy of the Mandibular Incisive Canal and Its Influence in Implant Therapy. A Scoping Review.

    Peña-Cardelles, Juan Francisco / Markovic, Jovana / Alanezi, Ahmad / Hamilton, Adam / Gallucci, German O / Lanis, Alejandro

    The International journal of periodontics & restorative dentistry

    2024  , Page(s) 1–27

    Abstract: Introduction: The interforaminal region is considered more favorable for implant placement than the posterior mandible in edentulous patients, mainly because of the interference of the inferior alveolar nerve with implant placement in the severely ... ...

    Abstract Introduction: The interforaminal region is considered more favorable for implant placement than the posterior mandible in edentulous patients, mainly because of the interference of the inferior alveolar nerve with implant placement in the severely resorbed posterior mandible. However, complications in the interforaminal region may occur due to the presence of the mandibular incisive nerve.
    Objective: This scoping review aims to describe the mandibular incisive nerve anatomy related to the potential interference in implant therapy.
    Material and methods: A comprehensive literature search was conducted in the following databases: MEDLINE (via PubMed), Web of Science, and Scopus. This scoping review was structured according to the Joanna Briggs Institute method.
    Results: Thirteen studies were included in the review. All the studies were observational cohort anatomical studies, carried out mainly by CBCT and on cadavers. A total of 1471 patients/cadavers were studied. The mandibular incisive nerve was presented in 87-100% of the cases, with an average length of 9.97 mm and an average diameter of 1.97 mm. The mandibular incisive nerve may be damaged during drilling and implant placement, especially using implant lengths larger than 12 mm.
    Conclusions: Damage to the mandibular incisive nerve due to implant placement could be present, however, it is necessary to conduct more studies focusing on assessing mandibular incisive nerve damage to understand the clinical relevance of this nerve and its associated morbidities such as neurosensorial alterations. Due to the different anatomical characteristics of this nerve, CBCT analysis is recommended for implant therapy in the anterior mandible to prevent the described complications.
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ISSN 1945-3388
    ISSN (online) 1945-3388
    DOI 10.11607/prd.6826
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  5. Article ; Online: Impact of digital technologies on implant surgery in fully edentulous patients: A scoping review.

    Lanis, Alejandro / Peña-Cardelles, Juan Francisco / Negreiros, William Matthew / Hamilton, Adam / Gallucci, German O

    Clinical oral implants research

    2024  

    Abstract: Background: For over three decades, digital technologies have been used in Implant Dentistry, beginning with the introduction of planning software for Static Computer-Assisted Implant Surgery (S-CAIS). During this time, this field has witnessed the ... ...

    Abstract Background: For over three decades, digital technologies have been used in Implant Dentistry, beginning with the introduction of planning software for Static Computer-Assisted Implant Surgery (S-CAIS). During this time, this field has witnessed the emergence of diverse methodologies and a proliferation of technological advancements. Today, S-CAIS is a widely adopted procedure for the placement of dental implants in both partially and fully edentulous patients, with Dynamic Computer-Assisted Surgery (D-CAIS) and Robotic-Assisted Implant Surgery (RAIS) rapidly gaining attention among dental professionals. The continuous advancements in this arena are not merely indicative of technological progress; they represent a steadfast dedication to refining precision, enhancing efficiency, and fostering innovation with the goal of optimizing patient outcomes in dental implantology.
    Aims: The purpose of the following review is to meticulously examine the spectrum of digital technologies available and to describe their protocols, advantages, and shortcomings as well as to evaluate their accuracy in implant surgery in patients with complete edentulism.
    Materials and methods: A scoping review was performed following the Joanna Briggs Institute (JBI) protocols, leveraging the population, concept, and context (PCC) framework to construct the research question and determine the inclusion and exclusion criteria.
    Results: Two hundred and sixty-seven records were identified for screening. After applying all the screening criteria, 41 articles were included for review and qualitative data analysis.
    Discussion: S-CAIS, D-CAIS, and RAIS were identified as the main technologies for computer assisted implant surgery. Their applications, characteristics, protocols and levels of accuracy were compared and described.
    Conclusion: Taking into consideration the limitations of this study, S-CAIS appears to be the most applied and validated technology in implant surgery for fully edentulous patients followed by D-CAIS and RAIS being these last two promising initiatives in the field. Despite having similar levels of accuracy, the overall comparison showed a slightly higher values in RAIS followed by D-CAIS and S-CAIS.
    Language English
    Publishing date 2024-04-13
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 1067626-0
    ISSN 1600-0501 ; 0905-7161
    ISSN (online) 1600-0501
    ISSN 0905-7161
    DOI 10.1111/clr.14268
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    Zs.A 3171: Show issues Location:
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  6. Article ; Online: Influence of scanning protocol on the accuracy of complete-arch digital implant scans: An in vitro study.

    Hamilton, Adam / Negreiros, William Matthew / Jain, Shruti / Finkelman, Matthew / Gallucci, German O

    Clinical oral implants research

    2024  

    Abstract: Objective: This in-vitro study assessed the influence of two intraoral scanning (IOS) protocols on the accuracy (trueness and precision) of digital scans performed in edentulous arches.: Methods: Twenty-two abutment-level master casts of edentulous ... ...

    Abstract Objective: This in-vitro study assessed the influence of two intraoral scanning (IOS) protocols on the accuracy (trueness and precision) of digital scans performed in edentulous arches.
    Methods: Twenty-two abutment-level master casts of edentulous arches with at least four implants were scanned repeatedly five times, each with two different scanning protocols. Protocol A (IOS-A) consisted of scanning the edentulous arch before inserting the implant scan bodies, followed by their insertion and its subsequent digital acquisition. Protocol B (IOS-B) consisted of scanning the edentulous arch with the scan bodies inserted from the outset. A reference scan from each edentulous cast was obtained using a laboratory scanner. Trueness and precision were calculated using the spatial fit analysis, cross-arch distance, and virtual Sheffield test. Statistical analysis was performed using generalized estimating equations (GEEs). Statistical significance was set at α = .05.
    Results: In the spatial fit test, the precision of average 3D distances was 45 μm (±23 μm) with protocol IOS-A and 25 μm (±10 μm) for IOS-B (p < .001), and the trueness of average 3D distances was 44 μm (±24 μm) with protocol IOS-A and 24 μm (±7 μm) for IOS-B (p < .001). Cross-arch distance precision was 59 μm (±53 μm) for IOS-A and 41 μm (±43 μm) for IOS-B (p = .0035), and trueness was 64 μm (±47 μm) for IOS-A and 50 μm (±40 μm) for IOS-B (p = .0021). Virtual Sheffield precision was 286 μm (±198 μm) for IOS-A and 146 μm (±92 μm) for IOS-B (p < .001), and trueness was 228 μm (±171 μm) for IOS-A and 139 μm (±92 μm) for IOS-B (p < .001).
    Conclusions: The IOS-B protocol demonstrated significantly superior accuracy. Placement of scan bodies before scanning the edentulous arch is recommended to improve the accuracy of complete-arch intraoral scanning.
    Language English
    Publishing date 2024-04-03
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1067626-0
    ISSN 1600-0501 ; 0905-7161
    ISSN (online) 1600-0501
    ISSN 0905-7161
    DOI 10.1111/clr.14259
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  7. Article ; Online: Considerations for predictable outcomes in static computer- aided implant surgery in the esthetic zone.

    Markovic, Jovana / Peña-Cardelles, Juan Francisco / Pedrinaci, Ignacio / Hamilton, Adam / Gallucci, German O / Lanis, Alejandro

    Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.

    2023  Volume 36, Issue 1, Page(s) 207–219

    Abstract: Objective: To provide technical and clinical recommendations for implementing a digital workflow in Static Computer-Aided Implant Surgery in the anterior maxilla.: Clinical considerations: An optimal 3D implant position is crucial for achieving ... ...

    Abstract Objective: To provide technical and clinical recommendations for implementing a digital workflow in Static Computer-Aided Implant Surgery in the anterior maxilla.
    Clinical considerations: An optimal 3D implant position is crucial for achieving satisfying results in implant rehabilitation in the esthetic area. Due to its complexity, implant placement in the esthetic zone should be executed with precision and predictability. Static Computer-Aided Implant Surgery requires thorough planning and detailed attention to every step of the digital workflow protocol.
    Conclusions: Implant positioning in the esthetic zone using Static Computer-Aided Implant Surgery is a technique-sensitive procedure that requires precise execution of each step. This approach ensures accurate prosthetically driven 3D implant placement and prevents potential errors that could lead to inaccurate positioning.
    Clinical significance: The proper implementation of Static Computer-Aided Implant Surgery may increase the level of agreement between the planned and definitive implant 3D positions in the esthetic zone, thus enhancing the esthetic outcomes of implant rehabilitation.
    MeSH term(s) Esthetics, Dental ; Dental Implantation, Endosseous/methods ; Surgery, Computer-Assisted/methods ; Maxilla/surgery ; Computers ; Computer-Aided Design ; Dental Implants ; Cone-Beam Computed Tomography
    Chemical Substances Dental Implants
    Language English
    Publishing date 2023-11-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2043146-6
    ISSN 1708-8240 ; 1496-4155
    ISSN (online) 1708-8240
    ISSN 1496-4155
    DOI 10.1111/jerd.13171
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    Zs.A 3314: Show issues Location:
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  8. Article ; Online: Multifunctional anatomical prototypes (MAPs): Treatment of excessive gingival display due to altered passive eruption.

    Pedrinaci, Ignacio / Calatrava, Javier / Flores, Juan / Hamilton, Adam / Gallucci, German O / Sanz, Mariano

    Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.

    2023  Volume 35, Issue 7, Page(s) 1058–1067

    Abstract: Objective: To describe a strategy using digital technologies for improving the diagnosis, treatment planning, and surgical execution of patients with excessive gingival display (EGD) due to altered passive eruption (APE).: Clinical considerations: An ...

    Abstract Objective: To describe a strategy using digital technologies for improving the diagnosis, treatment planning, and surgical execution of patients with excessive gingival display (EGD) due to altered passive eruption (APE).
    Clinical considerations: An important component for successful patient's management is to fulfill their esthetic expectations whilst delivering predictable and long-term therapeutic outcomes. To achieve this goal in patients with excessive gingival display due to altered passive eruption, it is essential to perform an accurate diagnosis and to communicate to the patient the expected customized results using digital technologies. Computer-aided designed and manufactured multifunctional anatomical prototypes (MAPs) may contribute to these purposes. Additionally, they can guide the surgical crown lengthening procedure or serve as a reference during the surgical guide fabrication providing information of the required anatomical landmarks.
    Conclusions: This novel strategy protocol for diagnosis, communication, and treatment management of patients with excessive gingival display follows functional and biological principles within the frame of a digital workflow, which improves the diagnostic capabilities, enhances communication, and guides the surgical treatment as shown in the 12 months follow-up of the reported case.
    Clinical significance: Developing a virtual patient by combining multiple digital data sets including cone-beam computed tomography (CBCT), intra-oral scans and digital photography, supports the clinician and the patient to achieve a comprehensive diagnosis and to better communicate the expected results to the patient. Furthermore, this digital treatment exercise based on anatomical and biological principles will facilitate the surgical precision and the achievement of successful outcomes, thus fulfilling the patient needs and expectations.
    MeSH term(s) Humans ; Esthetics, Dental ; Gingiva ; Tooth ; Tooth Crown ; Gingivectomy
    Language English
    Publishing date 2023-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2043146-6
    ISSN 1708-8240 ; 1496-4155
    ISSN (online) 1708-8240
    ISSN 1496-4155
    DOI 10.1111/jerd.13041
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  9. Article ; Online: Additively Manufactured Surgical Implant Guides: A Review.

    Elliott, Tom / Hamilton, Adam / Griseto, Neil / Gallucci, German O

    Journal of prosthodontics : official journal of the American College of Prosthodontists

    2022  Volume 31, Issue S1, Page(s) 38–46

    Abstract: Static computer assisted implant surgery (s-CAIS) is an integral part of the digital workflow in implant dentistry and provides the link between the virtual planning environment and surgical field. The accuracy of s-CAIS is influenced by many cumulative ... ...

    Abstract Static computer assisted implant surgery (s-CAIS) is an integral part of the digital workflow in implant dentistry and provides the link between the virtual planning environment and surgical field. The accuracy of s-CAIS is influenced by many cumulative factors including the fit of the template which is related to the manufacturing process. This critical review provides an overview of the current research on additively manufactured surgical implant guides.
    MeSH term(s) Computer-Aided Design ; Dental Implantation, Endosseous ; Dental Implants ; Surgery, Computer-Assisted
    Chemical Substances Dental Implants
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1197213-0
    ISSN 1532-849X ; 1059-941X
    ISSN (online) 1532-849X
    ISSN 1059-941X
    DOI 10.1111/jopr.13476
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  10. Article ; Online: Implant prosthodontic design as a predisposing or precipitating factor for peri-implant disease: A review.

    Hamilton, Adam / Putra, Armand / Nakapaksin, Pranai / Kamolroongwarakul, Pongrapee / Gallucci, German O

    Clinical implant dentistry and related research

    2023  Volume 25, Issue 4, Page(s) 710–722

    Abstract: Over the past decade, emerging evidence indicates a strong relationship between prosthetic design and peri-implant tissue health. The objective of this narrative review was to evaluate the evidence for the corresponding implant prosthodontic design ... ...

    Abstract Over the past decade, emerging evidence indicates a strong relationship between prosthetic design and peri-implant tissue health. The objective of this narrative review was to evaluate the evidence for the corresponding implant prosthodontic design factors on the risk to peri-implant tissue health. One of the most important factors to achieve an acceptable implant restorative design is the ideal implant position. Malpositioned implants often result in a restorative emergence profile at the implant-abutment junction that can restrict the access for patients to perform adequate oral hygiene. Inadequate cleansability and poor oral hygiene has been reported as a precipitating factors to induce the peri-implant mucositis and peri-implantitis and are influenced by restorative contours. The implant-abutment connection, restorative material selection and restoration design are also reported in the literature as having the potential to influence peri-implant sort tissue health.
    MeSH term(s) Humans ; Peri-Implantitis/etiology ; Dental Implants/adverse effects ; Precipitating Factors ; Prosthodontics ; Dental Materials
    Chemical Substances Dental Implants ; Dental Materials
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2094300-3
    ISSN 1708-8208 ; 1523-0899
    ISSN (online) 1708-8208
    ISSN 1523-0899
    DOI 10.1111/cid.13183
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