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Book ; Online: Locating Suburbia

Hamilton, Paula / Ashton, Paul

2013

Abstract: The identity of suburbia, so far as it can be ascribed one, is shifting and insecure, a borderline and liminal space. Dominant stereotypes have listed it as 'on the margins' beyond edges of cultural sophistication and tradition' and the areas that make ... ...

Abstract	The identity of suburbia, so far as it can be ascribed one, is shifting and insecure, a borderline and liminal space. Dominant stereotypes have listed it as 'on the margins' beyond edges of cultural sophistication and tradition' and the areas that make up 'sprawl'. But in the twenty-first century this static view has to be modified. As is evident from this collection, suburban dwellers themselves have redefined themselves. This collection explores the range and complexity of twenty-first century responses to city suburbs, predominantly in Sydney. It draws on a range of approaches - from history to creative non-fiction and multi-media
Keywords	Architecture ; Sports ; History (General)
Size	1 electronic resource (314 pages)
Publisher	UTS ePRESS
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT020589935
ISBN	9781863654326 ; 1863654321
DOI	10.5130/978-1-86365-432-6
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: What can the uptake of online pharmacy education in Scotland, during the COVID-19 pandemic, tells us about the future of CPD?

Zlotos, Leon / Hamilton, Peter / Park, Vicky / Stewart, Fiona

Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors

2024 Volume 34, Issue 5-6, Page(s) 277–286

Abstract: Pharmacy CPD in Scotland has been evolving towards online, asynchronous delivery since 2014. The COVID-19 pandemic accelerated this movement by restricting face-to-face education (Zlotos & Stewart, 2021). This study utilised Google analytics to describe ... ...

Abstract	Pharmacy CPD in Scotland has been evolving towards online, asynchronous delivery since 2014. The COVID-19 pandemic accelerated this movement by restricting face-to-face education (Zlotos & Stewart, 2021). This study utilised Google analytics to describe web traffic, and electronic e-learning completion records to describe learner activity on the Virtual Learning Environment of a national CPD provider in Scotland. The aim was to describe patterns of learning activity in the years spanning the COVID-19 pandemic, to help predict what future education practice may look like. This study identified that there was an increase in estimated time spent on learning from 8085.5 vs 16,061.5 hours of learning in 2018-19 and 2020-21, respectively. Completion of non-mandatory clinical modules and mandatory service modules increased each year. Mandatory, service focussed modules were most popular each year and the number of completions peaked to coincide with new services or updated content. The findings suggest asynchronous, online pharmacy education continues to grow in popularity. CPD providers should prioritise Mandatory, Service focussed education for pharmacy staff; although, they cannot neglect non-mandatory and Clinical education too. Future education for CPD should be designed to reflect the growing and diverse learner population.
MeSH term(s)	Humans ; Education, Distance ; Pandemics ; COVID-19/epidemiology ; Pharmacy ; Education, Pharmacy ; Scotland
Language	English
Publishing date	2024-01-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2074818-8
ISSN	1475-990X ; 1473-9879
ISSN (online)	1475-990X
ISSN	1473-9879
DOI	10.1080/14739879.2023.2272859
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Zs.A 3195: Show issues

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Article: Adaptive capabilities and fitness consequences associated with pollution exposure in fish

Hamilton, Patrick / Uren Webster, Tamsyn / tyler, charles

Philosophical transactions of the Royal Society of London / B, 372(1712):20160042

2017

Abstract: Many fish populations are exposed to harmful levels of chemical pollution and selection pressures associated with these exposures have led to the evolution of tolerance. Our understanding of the physiological basis for these adaptations is limited, but ... ...

Institution	Senckenberg Biodiversität und Klima Forschungszentrum
Abstract	Many fish populations are exposed to harmful levels of chemical pollution and selection pressures associated with these exposures have led to the evolution of tolerance. Our understanding of the physiological basis for these adaptations is limited, but they are likely to include processes involved with the absorption, distribution, metabolism and/or excretion of the target chemical. Other potential adaptive mechanisms include enhancements in antioxidant responses, an increased capacity for DNA and/or tissue repair and alterations to the life cycle of fish that enable earlier reproduction. Analysis of single-nucleotide polymorphism frequencies has shown that tolerance to hydrocarbon pollutants in both marine and estuarine fish species involves alteration in the expression of the xenobiotic metabolism enzyme CYP1A. In this review, we present novel data showing also that variants of the CYP1A gene have been under selection in guppies living in Trinidadian rivers heavily polluted with crude oil. Potential costs associated with these adaptations could reduce fitness in unpolluted water conditions. Integrating knowledge of local adaptation to pollution is an important future consideration in conservation practices such as for successful restocking, and improving connectivity within river systems. This article is part of the themed issue ‘Human influences on evolution, and the ecological and societal consequences’.
Keywords	chemical pollution ; adaptation ; genetics ; genetic adaptation ; environmental science ; ecology ; evolution ; fish ; single-nucleotide polymorphism ; tolerance
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article: Understanding the prevalence and distribution of fellowship trained female and male genitourinary reconstruction and men's health/andrology academic faculty in the United States.

Tuong, Mei N / Lombard, Hamilton P / Erickson, Bradley A

Translational andrology and urology

2023 Volume 12, Issue 9, Page(s) 1383–1389

Abstract: Background: We evaluated the prevalence, distribution, and specialist to population ratio of male and female reconstruction and andrology/prosthetics faculty within United States urologic training programs. Our objective was to help determine the ... ...

Abstract	Background: We evaluated the prevalence, distribution, and specialist to population ratio of male and female reconstruction and andrology/prosthetics faculty within United States urologic training programs. Our objective was to help determine the current need/demand for reconstructive fellowship trained faculty for necessary clinical exposure during residency in the midst of a nationwide residency expansion. Methods: All non-military urology residency programs were evaluated. Programs were sorted into their American Urologic Association Sections and websites were analyzed for evidence of fellowship training and/or clinical expertise/interest: (I) male genitourinary reconstruction (MGR); (II) female genitourinary reconstruction (FGR) and (III) infertility/andrology/men's health (AMH). The 2020 US Census data was used to determine specialist to population ratios by sections. Results: Of 137 evaluated programs, FGR had the highest percentage of fellowship-trained faculty (76%) followed by AMH (66%) and MGR (61%). Clinical/surgical interest was noted in pelvic organ prolapse (88%), inflatable penile prosthesis (79%) and urethral stricture disease (75%). Over 10% of training programs had two or more faculty with MGR, FGR and AMH fellowship training. Significant geographic variation amongst academic programs exists with the South and Southeastern parts of the US being relatively underserved, both in percentage of programs with fellowship-trained faculty, and by faculty per 1,000,000 inhabitants. Conclusions: The majority of US urology residencies have faculty with fellowship training and/or stated clinical interest in MGR, FGR and AMH. Still, many programs remain without these faculty while others have two or more in their respective fields. The geographic trends noted here have both educational and recruitment significance.
Language	English
Publishing date	2023-09-11
Publishing country	China
Document type	Journal Article
ZDB-ID	2851630-8
ISSN	2223-4691 ; 2223-4691 ; 2223-4683
ISSN (online)	2223-4691
ISSN	2223-4691 ; 2223-4683
DOI	10.21037/tau-23-159
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Republican Argument Against Nudging and Informed Consent.

Hamilton, Paul

HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues

2017 Volume 30, Issue 3, Page(s) 267–282

Abstract: I argue that it is impermissible to use nudges as a tool to influence patients in the context of informed consent. The motivation for such nudges is that their use can help reconcile potential conflicts between a physician's duty of beneficence and duty ... ...

Abstract	I argue that it is impermissible to use nudges as a tool to influence patients in the context of informed consent. The motivation for such nudges is that their use can help reconcile potential conflicts between a physician's duty of beneficence and duty to respect patient autonomy. I argue that their use places physicians in a position of domination over patients. That is, it violates the republican freedom of patients because it grants physicians the power to arbitrarily interfere. I also argue that if one tries to adjust the duty of beneficence to avoid this conclusion, then the republican freedom of patients is still threatened under conditions of clinical equipoise. As ways to avoid the inevitability of nudging, I suggest the alternative of boosting or the pairing of patients with physicians who share their deep values. This latter option achieves the benefits nudging patients is supposed to provide without violating the republican freedom of those patients.
MeSH term(s)	Coercion ; Decision Making/ethics ; Humans ; Informed Consent/psychology ; Informed Consent/standards ; Personal Autonomy ; Politics
Language	English
Publishing date	2017-12-27
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1042368-0
ISSN	1572-8498 ; 0956-2737
ISSN (online)	1572-8498
ISSN	0956-2737
DOI	10.1007/s10730-017-9343-2
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Zs.A 2996: Show issues

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Article ; Online: Evolocumab and clinical outcomes in patients with cardiovascular disease.

Hamilton, Paul

Annals of clinical biochemistry

2017 Volume 54, Issue 4, Page(s) 511

Language	English
Publishing date	2017
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	390309-6
ISSN	1758-1001 ; 0004-5632
ISSN (online)	1758-1001
ISSN	0004-5632
DOI	10.1177/0004563217705053
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Article ; Online: Polarization purity for active stabilization of diode laser injection lock.

Niederriter, R D / Marques Van Der Put, I / Hamilton, P

The Review of scientific instruments

2021 Volume 92, Issue 8, Page(s) 83004

Abstract: Injection locking of diode lasers is commonly used to amplify low power laser light but is extremely sensitive to perturbations in the laser current and temperature. To counter such perturbations, active stabilization is often applied to the current of ... ...

Abstract	Injection locking of diode lasers is commonly used to amplify low power laser light but is extremely sensitive to perturbations in the laser current and temperature. To counter such perturbations, active stabilization is often applied to the current of the injection locked diode. We observe that the diode laser's polarization extinction ratio (PER) greatly increases when injection locked, and therefore the PER provides a measure of injection lock quality. We report robust active stabilization of a diode laser injection lock based on the PER, demonstrating the technique at 399 nm wavelength where injection locking is typically less stable than at longer wavelengths. The PER provides a feedback error signal that is compatible with standard proportional integral differential servo controllers, requires no additional optical components beyond the optical isolator typically used in injection locking, and enables a large feedback bandwidth.
Language	English
Publishing date	2021-09-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	209865-9
ISSN	1089-7623 ; 0034-6748
ISSN (online)	1089-7623
ISSN	0034-6748
DOI	10.1063/5.0059824
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Article ; Online: Thromboembolism in nephrotic syndrome: controversies and uncertainties.

Parker, Kathrine / Ragy, Omar / Hamilton, Patrick / Thachil, Jecko / Kanigicherla, Durga

Research and practice in thrombosis and haemostasis

2023 Volume 7, Issue 6, Page(s) 102162

Abstract: Thromboembolism is one of the most serious complications of nephrotic syndrome, including both arterial and venous thromboembolic events. Rates of thromboembolism depend on a multitude of factors, including the severity and cause of nephrotic syndrome, ... ...

Abstract	Thromboembolism is one of the most serious complications of nephrotic syndrome, including both arterial and venous thromboembolic events. Rates of thromboembolism depend on a multitude of factors, including the severity and cause of nephrotic syndrome, with primary membranous nephropathy having the highest reported rates. In relation to arterial thromboembolism, the risk can be as high as 8 times that of an age- and sex-matched population. However, extrapolating risks is challenging, with published studies not being homogeneous, several being single center and retrospective, and including different causes of primary nephrotic syndrome. Determining thromboembolic risk in nephrotic syndrome is essential to enable decision making on preventive strategies. However, lack of proven strategies to help estimate risk-benefit aspects underpins variations in clinical practice. Although the use of anticoagulation following a thrombotic event is clear, this still leaves us with a clinical dilemma as to if, and who, should receive prophylactic anticoagulation, with what agent, and for how long. In the absence of clear evidence to answer these questions, prophylactic anticoagulation strategies for nephrotic syndrome currently rely on expert consensus opinion, such as in the recently published 2021 Kidney Disease Improving Global Outcomes glomerular disease guidelines. In the mainstay, these recommendations relate to patients with membranous nephropathy. Here, we detail the current controversies still faced by clinicians around the risk of thromboembolism in nephrotic syndrome, use of prophylactic anticoagulation in nephrotic syndrome and propose ways of advancing existing knowledge and practice in this field to unravel the conundrum.
Language	English
Publishing date	2023-08-09
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2475-0379
ISSN (online)	2475-0379
DOI	10.1016/j.rpth.2023.102162
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Neural suppression in odor recognition memory.

Eek, Tom / Lundin, Fredrik / Larsson, Maria / Hamilton, Paul / Georgiopoulos, Charalampos

Chemical senses

2023 Volume 48

Abstract: Little is known about the neural basis of lower- and higher-order olfactory functions such as odor memory, compared with other sensory systems. The aim of this study was to explore neural networks and correlates associated with 3 functions: passive ... ...

Abstract	Little is known about the neural basis of lower- and higher-order olfactory functions such as odor memory, compared with other sensory systems. The aim of this study was to explore neural networks and correlates associated with 3 functions: passive smelling (PS), odor encoding (OE), and in particular odor recognition memory (ORM). Twenty-six healthy participants were examined using functional magnetic resonance imaging conducted across 3 sessions, one for each function. Independent component analysis revealed a difference between sessions where a distinct ORM component incorporating hippocampus and posterior cingulate showed delayed triggering dissociated from odor stimulation and recognition. By contrasting Hit for ORM (target odors correctly recognized as old) and a combination of PS and detected odors from OE, we found significantly lower activations in amygdala, piriform cortex, insula, thalamus, and the inferior parietal lobule. Region of interest analysis including anterior insula, posterior cingulate gyrus, dentate gyrus, left middle frontal gyrus, amygdala, and piriform cortex demonstrated that Hit were associated with lower activations compared with other memory responses. In summary, our findings suggest that successful recognition of familiar odors (odor familiarity) is associated with neural suppression in the abovementioned regions of interest. Additionally, network including the hippocampus and posterior cingulate is engaged in a postrecognition process. This process may be related to incidental encoding of less familiar and more novel odors (odor novelty) and should be subject for future research.
MeSH term(s)	Humans ; Odorants ; Smell/physiology ; Recognition, Psychology ; Hippocampus ; Amygdala ; Magnetic Resonance Imaging ; Brain/physiology ; Brain Mapping/methods
Language	English
Publishing date	2023-01-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	754122-3
ISSN	1464-3553 ; 0379-864X
ISSN (online)	1464-3553
ISSN	0379-864X
DOI	10.1093/chemse/bjad001
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Article ; Online: Review of the utility of routine mortality reviews among deaths on General Internal Medicine wards in a Canadian tertiary care hospital.

Tran, Kelvin / Padwal, Raj / Hamilton, Peter / Ngo, Jennifer

BMJ open quality

2022 Volume 11, Issue 4

Abstract: Background: Hospital morbidity and mortality reviews are common quality assurance activities, intended to uncover latent or unrecognised systemic issues that contribute to preventable adverse events and patient harm. Mortality reviews may be routinely ... ...

Abstract	Background: Hospital morbidity and mortality reviews are common quality assurance activities, intended to uncover latent or unrecognised systemic issues that contribute to preventable adverse events and patient harm. Mortality reviews may be routinely mandated by hospital policy or for accreditation purposes. However, patients under the care of certain specialties, such as general internal medicine (GIM), are affected by a substantial burden of chronic disease, advanced age, frailty or limited life expectancy. Many of their deaths could be viewed as reasonably foreseeable, and unrelated to poor-quality care. Methods: We sought to determine how frequently postmortem chart reviews for hospitalised GIM patients at our tertiary care centre in Canada would uncover patient safety or quality of care issues that directly led to these patients' deaths. We reviewed the charts of all patients who died while admitted to the GIM admitting service over a 12-month time period between 1 July 2020 and 30 June 2021. Results: We found that in only 2% of cases was a clinical adverse event detected that directly contributed to a poor or unexpected outcome for the patient, and of those cases, more than half were related to unfortunate nosocomial transmission of COVID-19 infection. Conclusion: Due to an overall low yield, we discourage routine mortality chart reviews for general medical patients, and instead suggest that organisations focus on strategies to recognise and capture safety incidents that may not necessarily result in death.
MeSH term(s)	Humans ; Tertiary Care Centers ; Canada ; COVID-19 ; Internal Medicine ; Quality of Health Care
Language	English
Publishing date	2022-11-07
Publishing country	England
Document type	Review ; Journal Article
ISSN	2399-6641
ISSN (online)	2399-6641
DOI	10.1136/bmjoq-2022-001933
Database	MEDical Literature Analysis and Retrieval System OnLINE

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