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  1. AU="Hamilton, Shelia M"
  2. AU="Nichols, J Wylie"
  3. AU="Pesce R."
  4. AU="Gambitta, P"
  5. AU="Imran, Aqeel"
  6. AU="Sharma, Yashoda"
  7. AU="Kosai, Jordyn"
  8. AU="Aroca Ferri, María"
  9. AU="Laba, Stephanie"
  10. AU="Kim, Ye-Sel"

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  1. Artikel: Ultraviolet dosage and decontamination efficacy were widely variable across 14 UV devices after testing a dried enveloped ribonucleic acid virus surrogate for SARS-CoV-2.

    Buhr, Tony L / Borgers-Klonkowski, Erica / Gutting, Bradford W / Hammer, Emlyn E / Hamilton, Shelia M / Huhman, Brett M / Jackson, Stuart L / Kennihan, Neil L / Lilly, Samuel D / Little, John D / Luck, Brooke B / Matuczinski, Emily A / Miller, Charles T / Sides, Rachel E / Yates, Vanessa L / Young, Alice A

    Frontiers in bioengineering and biotechnology

    2022  Band 10, Seite(n) 875817

    Abstract: Aims: ...

    Abstract Aims:
    Sprache Englisch
    Erscheinungsdatum 2022-10-04
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.875817
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Ultraviolet Dosage and Decontamination Efficacy was Widely Variable Across 14 UV Devices after Testing a Dried Enveloped Ribonucleic Acid Virus Surrogate for SARS-CoV-2

    Buhr, Tony L / Borgers-Klonkowski, Erica / Gutting, Bradford W / Hammer, Emlyn E / Hamilton, Shelia M / Huhman, Brett M / Jackson, Stuart L / Kennihan, Neil L / Lilly, Samuel D / Little, John D / Luck, Brooke B. / Matuczinski, Emily A / Miller, Charles T / Sides, Rachel E / Yates, Vanessa L / Young, Alice A

    bioRxiv

    Abstract: Aims: The dosages and efficacy of 14 ultraviolet (UV) decontamination technologies were measured against a SARS-CoV-2 surrogate virus that was dried on to different materials for lab and field testing. Methods and Results: A live enveloped, ribonucleic ... ...

    Abstract Aims: The dosages and efficacy of 14 ultraviolet (UV) decontamination technologies were measured against a SARS-CoV-2 surrogate virus that was dried on to different materials for lab and field testing. Methods and Results: A live enveloped, ribonucleic acid virus surrogate for SARS-CoV-2 was dried on stainless steel 304 (SS304), Navy Top Coat-painted SS304 (NTC), cardboard, polyurethane, polymethyl methacrylate (PMMA), and acrylonitrile butadiene styrene (ABS) at > 8.0 log10 plaque-forming units (PFU) per test coupon. The coupons were then exposed to UV light during both lab and field testing. Commercial and prototype UV-emitting devices were measured for efficacy; 4 handheld devices, 3 room/surface-disinfecting machines, 5 air-disinfection devices, and 2 larger custom-made machines. UV device dosages ranged from 0.01-729 mJ cm-2. Anti-viral efficacy among the different UV devices ranged from no decontamination up to nearly achieving sterilization. Importantly, cardboard required far more dosage than SS304. Conclusions: Enormous variability in dosage and efficacy was measured among the different UV devices. Porous materials limit the utility of UV decontamination. Significance and Impact of the Study: UV devices have wide variability in dosages, efficacy, hazards, and UV output over time indicating that each UV device needs independent technical measurement and assessment for product development, and prior to use.
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2022-01-27
    Verlag Cold Spring Harbor Laboratory
    Dokumenttyp Artikel ; Online
    DOI 10.1101/2022.01.27.478063
    Datenquelle COVID19

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  3. Artikel: Hot, Humid Air Decontamination of Aircraft Confirmed That High Temperature and High Humidity Are Critical for Inactivation of Infectious, Enveloped Ribonucleic Acid (RNA) Virus.

    Buhr, Tony L / Young, Alice A / Borgers-Klonkowski, Erica / Kennihan, Neil L / Barnette, Harold K / Minter, Zachary A / Bohmke, Matthew D / Osborn, Emily B / Hamilton, Shelia M / Kimani, Monique B / Hammon, Mark W / Miller, Charles T / Mackie, Ryan S / Innocenti, Jennifer M / Bensman, Misty D / Gutting, Bradford W / Lilly, Samuel D / Hammer, Emlyn E / Yates, Vanessa L /
    Luck, Brooke B

    Frontiers in bioengineering and biotechnology

    2020  Band 8, Seite(n) 592621

    Abstract: Aims: ...

    Abstract Aims:
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-10-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2020.592621
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel ; Online: Hot, humid air decontamination of aircraft confirmed that high temperature and high humidity are critical for inactivation of infectious, enveloped ribonucleic acid (RNA) virus

    Buhr, Tony L. / Young, Alice A. / Borgers-Klonkowski, Erica / Kennihan, Neil L. / Barnette, Harold K. / Minter, Zachary A. / Bohmke, Matthew D. / Osborn, Emily B. / Hamilton, Shelia M. / Kimani, Monique B. / Hammon, Mark W. / Miller, Charles T. / Mackie, Ryan S. / Innocenti, Jennifer M. / Bensman, Misty D. / Gutting, Bradford W. / Lilly, Samuel D. / Hammer, Emlyn E. / Yates, Vanessa L. /
    Luck, Brooke B.

    bioRxiv

    Abstract: Aims To develop infectious (live/dead) enveloped virus test indicators and Response Surface Methodology (RSM) models that evaluate survival of an enveloped ribonucleic acid (RNA) virus on contaminated aircraft materials after exposure to hot, humid air ( ... ...

    Abstract Aims To develop infectious (live/dead) enveloped virus test indicators and Response Surface Methodology (RSM) models that evaluate survival of an enveloped ribonucleic acid (RNA) virus on contaminated aircraft materials after exposure to hot, humid air (HHA). Methods and Results Enveloped RNA bacteriophage Phi6 (Φ6) was dried on wiring insulation, aircraft performance coating (APC), polypropylene, and nylon at ≥ 8 log10 plaque-forming units (PFU) test coupon-1. Only 2.4 log10 inactivation was measured on APC at 70°Celsius (°C), 5% relative humidity (RH) after 24 h. In contrast, HHA RSM models showed a 90% probability of a 7-log10 inactivation at ≥63°C, 90% RH after 1 h, and decontamination kinetics were similar across different materials. HHA decontamination of C-130 and C-17 aircraft showed >7 log10 and ≥5.9 log10 inactivation of enveloped virus on 100 and 110 test indicators, respectively, with a 1-h treatment, excluding ramp-up and ramp-down times. Conclusions Enveloped RNA virus test indicators were successfully developed, lab tested for HHA decontamination, analyzed for RSM, and field-tested in aircraft demonstrations. Significance and Impact of the Study The utility of HHA decontamination was demonstrated after inactivating enveloped RNA virus on aircraft with a 1-h HHA treatment within aircraft temperature and RH limits.
    Schlagwörter covid19
    Verlag BioRxiv
    Dokumenttyp Artikel ; Online
    DOI 10.1101/2020.07.20.212365
    Datenquelle COVID19

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