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  1. Book: Multifaceted biomedical applications of graphene

    Han, Dong-Wook / Hong, Suck Won

    (Advances in experimental medicine and biology ; 1351)

    2022  

    Author's details Dong-Wook Han, Suck Won Hong editors
    Series title Advances in experimental medicine and biology ; 1351
    Collection
    Keywords Biomedical materials ; Graphene/Industrial applications
    Subject code 610.284
    Language English
    Size viii, 264 Seiten, Illustrationen, 24 cm
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book
    HBZ-ID HT021264959
    ISBN 978-981-16-4922-6 ; 9789811649233 ; 981-16-4922-7 ; 9811649235
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -1351- not available for loan Lesesaal EG

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  2. Book ; Online: The Two Faces of Nanomaterials : Toxicity and Bioactivity

    Han, Dong-Wook / Atabaev, Timur Sh

    2020  

    Keywords Research & information: general ; Biology, life sciences ; black phosphorus ; 2D nanomaterial ; cytotoxicity ; biomedical application ; multifunctional magnetic nanoparticles ; chlorin e6 ; folic acid ; in vivo penetration depth ; cancer cell targeting ; cell cycle ; nanoparticle location ; surface biocompatibility ; microtubule ; proteomics ; graphene ; h-BN ; nanostructured coatings ; biofilms ; E. cloacae ; carbon nanomaterials ; unique properties ; biomedical applications ; in vitro toxicity ; in vivo toxicity ; ZnO nanostructures ; toxicity ; biocompatibility ; physicochemical properties ; cells viability assays ; in vivo experiments ; fullerene derivatives ; drug-like descriptors ; binding activity ; cheminformatics ; neural networks modelling ; hydrogenation ; pharmacology ; toxicology
    Size 1 electronic resource (146 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021044243
    ISBN 9783039289844 ; 3039289845
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Virus-Based Nanomaterials and Nanostructures

    Han, Dong-Wook / Oh, Jin-Woo

    2020  

    Keywords History of engineering & technology ; virus-like particles ; glioblastoma ; convection-enhanced delivery ; tobacco mosaic virus ; bioconjugation ; doxorubicin ; drug delivery ; protein-based nanomaterials ; viral capsid ; VLPs ; hepatitis B virus capsid protein ; HBc ; viral self-assembly ; magnetic core ; HBcAg ; BmNPV bacmid ; nanobiomaterials ; Neospora caninum ; Neospora caninum profilin ; neosporosis ; silkworm expression system ; ZnS ; bio/inorganic hybrid materials ; hydrophobization ; polymer coupling ; virus ; tissue regeneration ; biomimetic nanocomposites ; phage display ; nano-vaccines ; HIV-1 Env trimers ; B-cell targeting ; intrastructural help ; VNPs ; Hsp60 ; IBD ; autoantibody ; inflammation ; diagnosis ; biosensor ; M13 bacteriophage ; color sensor ; energy generator ; piezoelectric ; self-assembly ; genetic engineering ; multi-array sensors ; hierarchical cluster analysis ; high selectivity ; piezoelectric materials ; organic materials ; biomaterials ; energy applications ; biomedical applications ; virus-based nanomaterials ; energy devices ; piezoelectric biomaterials
    Size 1 electronic resource (178 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021044700
    ISBN 9783039286959 ; 3039286951
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Frontiers in Toxicity and Functionalization of Nanomaterials

    Chrzanowski, Wojciech / Han, Dong-Wook

    2018  

    Abstract: Over the last decade, various nanomaterials (NMs) have attracted tremendous attention with the incredible development in nanoscience and nanotechnology. Some NMs are explored increasingly for biomedical applications, including drug delivery carriers, ... ...

    Abstract Over the last decade, various nanomaterials (NMs) have attracted tremendous attention with the incredible development in nanoscience and nanotechnology. Some NMs are explored increasingly for biomedical applications, including drug delivery carriers, imaging probes, antimicrobial agents, biosensors, and tissue engineering scaffolds. However, the in vitro and in vivo toxicities of NMs related to oxidative stress are the main obstacles to use them in biomedical fields. One of the most promising strategies to address these obstacles is functionalizing NMs with biocompatible molecules or materials. In this Special Issue, we are especially interested in manuscripts that advance the understanding of the interaction of NMs with cells, such as cellular responses to NMs, intracellular behaviors of NMs, therapeutic and imaging potentials of NMs, as well as the functionalization of NMs through coating, patterning and hybridization with other biomolecules for multifaceted biomedical applications
    Keywords Chemistry
    Size 1 electronic resource (182 p.)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020097962
    ISBN 9783038427360 ; 9783038427353 ; 3038427365 ; 3038427357
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: Nanofibrous Material-Reinforced Printable Ink for Enhanced Cell Proliferation and Tissue Regeneration.

    Raja, Iruthayapandi Selestin / Kim, Bongju / Han, Dong-Wook

    Bioengineering (Basel, Switzerland)

    2024  Volume 11, Issue 4

    Abstract: The three-dimensional (3D) printing of biomaterials, cells, and bioactive components, including growth factors, has gained interest among researchers in the field of tissue engineering (TE) with the aim of developing many scaffolds to sustain size, shape ...

    Abstract The three-dimensional (3D) printing of biomaterials, cells, and bioactive components, including growth factors, has gained interest among researchers in the field of tissue engineering (TE) with the aim of developing many scaffolds to sustain size, shape fidelity, and structure and retain viable cells inside a network. The biocompatible hydrogel employed in 3D printing should be soft enough to accommodate cell survival. At the same time, the gel should be mechanically strong to avoid the leakage of cells into the surrounding medium. Considering these basic criteria, researchers have developed nanocomposite-based printable inks with suitable mechanical and electroconductive properties. These nanomaterials, including carbon family nanomaterials, transition metal dichalcogenides, and polymeric nanoparticles, act as nanofillers and dissipate stress across polymeric networks through their electroactive interactions. Nanofiber-reinforced printable ink is one kind of nanocomposite-based ink that comprises dispersed nanofiber components in a hydrogel matrix. In this current review, we compile various TE applications of nanofiber-reinforced printable ink and describe the 3D-printing parameters, classification, and impact of cross-linkage. Furthermore, we discuss the challenges and future perspectives in this field.
    Language English
    Publishing date 2024-04-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering11040363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Cytoprotective Effects of Baicalein on H

    Kim, Gyeonghyeon / Han, Dong-Wook / Lee, Jong Hun

    Antioxidants (Basel, Switzerland)

    2023  Volume 12, Issue 4

    Abstract: Reactive oxygen species (ROS) promote oxidative stress, which directly causes molecular damage and disrupts cellular homeostasis, leading to skin aging. Baicalein, a flavonoid compound isolated from the root ... ...

    Abstract Reactive oxygen species (ROS) promote oxidative stress, which directly causes molecular damage and disrupts cellular homeostasis, leading to skin aging. Baicalein, a flavonoid compound isolated from the root of
    Language English
    Publishing date 2023-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12040902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Cytoprotective Effects of Baicalein on H2O2-Induced ROS by Maintaining Mitochondrial Homeostasis and Cellular Tight Junction in HaCaT Keratinocytes

    Kim, Gyeonghyeon / Han, Dong-Wook / Lee, Jong Hun

    Antioxidants. 2023 Apr. 10, v. 12, no. 4

    2023  

    Abstract: Reactive oxygen species (ROS) promote oxidative stress, which directly causes molecular damage and disrupts cellular homeostasis, leading to skin aging. Baicalein, a flavonoid compound isolated from the root of Scutellaria baicalensis Georgi has ... ...

    Abstract Reactive oxygen species (ROS) promote oxidative stress, which directly causes molecular damage and disrupts cellular homeostasis, leading to skin aging. Baicalein, a flavonoid compound isolated from the root of Scutellaria baicalensis Georgi has antioxidant, anticancer, anti-inflammatory, and other medicinal properties. We aimed to investigate the protective effect of baicalein on the disruption of tight junctions and mitochondrial dysfunction caused by H₂O₂-induced oxidative stress in HaCaT keratinocytes. The cells were pretreated with 20 and 40 µM baicalein followed by treatment with 500 µM H₂O₂. The results revealed that baicalein exerted antioxidant effects by reducing intracellular ROS production. Baicalein attenuated the degradation of the ECM (MMP-1 and Col1A1) and the disruption of tight junctions (ZO-1, occludin, and claudin-4). In addition, baicalein prevented mitochondrial dysfunction (PGC-1α, PINK1, and Parkin) and restored mitochondrial respiration. Furthermore, baicalein regulated the expression of antioxidant enzymes, including NQO-1 and HO-1, via the Nrf2 signaling pathway. Our data suggest that the cytoprotective effects of baicalein against H₂O₂-induced oxidative stress may be mediated through the Nrf2/NQO-1/HO-1 signaling pathway. In conclusion, baicalein exerts potent antioxidant effects against H₂O₂-induced oxidative stress in HaCaT keratinocytes by maintaining mitochondrial homeostasis and cellular tight junctions.
    Keywords Scutellaria baicalensis ; flavonoids ; homeostasis ; keratinocytes ; mitochondria ; occludins ; oxidative stress ; protective effect ; reactive oxygen species ; tight junctions
    Language English
    Dates of publication 2023-0410
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12040902
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Reflections and Outlook on Multifaceted Biomedical Applications of Graphene.

    Raja, Iruthayapandi Selestin / Hong, Suck Won / Han, Dong-Wook

    Advances in experimental medicine and biology

    2022  Volume 1351, Page(s) 253–264

    Abstract: Two-dimensional nanomaterials have been widely explored by researchers due to their nanosized thickness and quantum size effect. They were layered double hydroxides, transition metal dichalcogenides, transition metal oxides, and synthetic silicate clays. ...

    Abstract Two-dimensional nanomaterials have been widely explored by researchers due to their nanosized thickness and quantum size effect. They were layered double hydroxides, transition metal dichalcogenides, transition metal oxides, and synthetic silicate clays. Among the 2D nanomaterials, graphene and their derivatives were investigated extensively at first as they exhibited exceptional conductivity and a zero-band gap semimetal nature. Though graphene family nanomaterials (GFNs) were utilized for several physicochemical applications, including electronic, electric, mechanic, photonic, magnetic, and catalytic devices, their biomedical applications are still meritorious. Biosensor, bioimaging, drug delivery, tumor ablation, and tissue regeneration are some of them. The outlook of the present book chapters encompasses the preparation of GFNs, physicochemical properties, biomedical applications, biosafety, and their future directions.
    MeSH term(s) Biosensing Techniques ; Drug Delivery Systems ; Graphite/chemistry ; Nanostructures/chemistry ; Oxides
    Chemical Substances Oxides ; Graphite (7782-42-5)
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-16-4923-3_12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Virus-Based Nanomaterials and Nanostructures.

    Oh, Jin-Woo / Han, Dong-Wook

    Nanomaterials (Basel, Switzerland)

    2020  Volume 10, Issue 3

    Abstract: This Special Issue highlights the recent developments and future directions of virus-based nanomaterials and nanostructures in energy and biomedical applications. The virus-based biomimetic materials formulated using innovative ideas presented herein are ...

    Abstract This Special Issue highlights the recent developments and future directions of virus-based nanomaterials and nanostructures in energy and biomedical applications. The virus-based biomimetic materials formulated using innovative ideas presented herein are characterized for the applications of biosensors and nanocarriers. The research contributions and trends based on virus-based materials, covering energy-harvesting devices to tissue regeneration over the last two decades, are described and discussed.
    Language English
    Publishing date 2020-03-20
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano10030567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Editorial: Fluorescent Carbon-Based Nanostructures for Bioimaging Applications.

    Atabaev, Timur Sh / Han, Dong-Wook

    Frontiers in chemistry

    2020  Volume 8, Page(s) 587918

    Language English
    Publishing date 2020-09-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2020.587918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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