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  1. Book ; Online: Feedback Capacity of OU-Colored AWGN Channels

    Su, Jun / Han, Guangyue / Shamai, Shlomo

    2023  

    Abstract: We derive an explicit feedback capacity formula for the OU-Colored AWGN channel. Among many others, this result shows that at least in some cases, the continuous-time Schalkwijk-Kailath coding scheme achieves the feedback capacity for such a channel, and ...

    Abstract We derive an explicit feedback capacity formula for the OU-Colored AWGN channel. Among many others, this result shows that at least in some cases, the continuous-time Schalkwijk-Kailath coding scheme achieves the feedback capacity for such a channel, and feedback may not increase the capacity of a continuous-time ACGN channel even if the noise process is colored.
    Keywords Computer Science - Information Theory
    Publishing date 2023-02-25
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: On Continuous-Time Gaussian Channels.

    Liu, Xianming / Han, Guangyue

    Entropy (Basel, Switzerland)

    2019  Volume 21, Issue 1

    Abstract: A continuous-time white Gaussian channel can be formulated using a white Gaussian noise, and a conventional way for examining such a channel is the sampling approach based on the Shannon-Nyquist sampling theorem, where the original continuous-time ... ...

    Abstract A continuous-time white Gaussian channel can be formulated using a white Gaussian noise, and a conventional way for examining such a channel is the sampling approach based on the Shannon-Nyquist sampling theorem, where the original continuous-time channel is converted to an equivalent discrete-time channel, to which a great variety of established tools and methodology can be applied. However, one of the key issues of this scheme is that continuous-time feedback and memory cannot be incorporated into the channel model. It turns out that this issue can be circumvented by considering the Brownian motion formulation of a continuous-time white Gaussian channel. Nevertheless, as opposed to the white Gaussian noise formulation, a link that establishes the information-theoretic connection between a continuous-time channel under the Brownian motion formulation and its discrete-time counterparts has long been missing. This paper is to fill this gap by establishing causality-preserving connections between continuous-time Gaussian feedback/memory channels and their associated discrete-time versions in the forms of sampling and approximation theorems, which we believe will play important roles in the long run for further developing continuous-time information theory. As an immediate application of the approximation theorem, we propose the so-called approximation approach to examine continuous-time white Gaussian channels in the point-to-point or multi-user setting. It turns out that the approximation approach, complemented by relevant tools from stochastic calculus, can enhance our understanding of continuous-time Gaussian channels in terms of giving alternative and strengthened interpretation to some long-held folklore, recovering "long-known" results from new perspectives, and rigorously establishing new results predicted by the intuition that the approximation approach carries. More specifically, using the approximation approach complemented by relevant tools from stochastic calculus, we first derive the capacity regions of continuous-time white Gaussian multiple access channels and broadcast channels, and we then analyze how feedback affects their capacity regions: feedback will increase the capacity regions of some continuous-time white Gaussian broadcast channels and interference channels, while it will not increase capacity regions of continuous-time white Gaussian multiple access channels.
    Language English
    Publishing date 2019-01-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e21010067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Surveillance of SARS-CoV-2 in wastewater by quantitative PCR and digital PCR: a case study in Shijiazhuang city, Hebei province, China.

    Chai, Xiaoru / Liu, Shiyou / Liu, Chao / Bai, Jiaxuan / Meng, Juntao / Tian, Hong / Han, Xu / Han, Guangyue / Xu, Xiangdong / Li, Qi

    Emerging microbes & infections

    2024  Volume 13, Issue 1, Page(s) 2324502

    Abstract: In this study, we reported the first long-term monitoring of SARS-CoV-2 in wastewater in Mainland China from November 2021 to October 2023. The city of Shijiazhuang was employed for this case study. We developed a triple reverse transcription droplet ... ...

    Abstract In this study, we reported the first long-term monitoring of SARS-CoV-2 in wastewater in Mainland China from November 2021 to October 2023. The city of Shijiazhuang was employed for this case study. We developed a triple reverse transcription droplet digital PCR (RT-ddPCR) method using triple primer-probes for simultaneous detection of the N1 gene, E gene, and Pepper mild mottle virus (PMMoV) to achieve accurate quantification of SARS-CoV-2 RNA in wastewater. Both the RT-ddPCR method and the commercial multiplex reverse transcription quantitative polymerase chain reaction (RT-qPCR) method were implemented for the detection of SARS-CoV-2 in wastewater in Shijiazhuang City over a 24-month period. Results showed that SARS-CoV-2 was detected for the first time in the wastewater of Shijiazhuang City on 10 November 2022. The peak of COVID-19 cases occurred in the middle of December 2022, when the concentration of SARS-CoV-2 in the wastewater was highest. The trend of virus concentration increases and decreases forming a "long-tailed" shape in the COVID-19  outbreak and recession cycle. The results indicated that both multiplex RT-ddPCR and RT-qPCR are effective in detecting SARS-CoV-2 in wastewater, but RT-ddPCR is capable of detecting low concentrations of SARS-CoV-2 in wastewater which is more efficient. The SARS-CoV-2 abundance in wastewater is correlated to clinical data, outlining the public health utility of this work.HighlightsFirst long-term monitoring of SARS-CoV-2 in wastewater in Mainland ChinaCOVID-19 outbreak was tracked in Shijiazhuang City from outbreak to containmentWastewater was monitored simultaneously using RT-ddPCR and RT-qPCR methodsTriple primer-probe RT-ddPCR detects N1 and E genes of SARS-CoV-2 and PMMoV.
    MeSH term(s) Humans ; SARS-CoV-2/genetics ; Wastewater ; COVID-19/diagnosis ; COVID-19/epidemiology ; RNA, Viral/genetics ; China/epidemiology ; Multiplex Polymerase Chain Reaction ; COVID-19 Testing ; Tobamovirus
    Chemical Substances Wastewater ; RNA, Viral
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2681359-2
    ISSN 2222-1751 ; 2222-1751
    ISSN (online) 2222-1751
    ISSN 2222-1751
    DOI 10.1080/22221751.2024.2324502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Isometries and MacWilliams Extension Property for Weighted Poset Metric

    Xu, Yang / Kan, Haibin / Han, Guangyue

    2022  

    Abstract: Let $\mathbf{H}$ be the cartesian product of a family of left modules over a ring $S$, indexed by a finite set $\Omega$. We are concerned with the $(\mathbf{P},\omega)$-weight on $\mathbf{H}$, where $\mathbf{P}=(\Omega,\preccurlyeq_{\mathbf{P}})$ is a ... ...

    Abstract Let $\mathbf{H}$ be the cartesian product of a family of left modules over a ring $S$, indexed by a finite set $\Omega$. We are concerned with the $(\mathbf{P},\omega)$-weight on $\mathbf{H}$, where $\mathbf{P}=(\Omega,\preccurlyeq_{\mathbf{P}})$ is a poset and $\omega:\Omega\longrightarrow\mathbb{R}^{+}$ is a weight function. We characterize the group of $(\mathbf{P},\omega)$-weight isometries of $\mathbf{H}$, and give a canonical decomposition for semi-simple subcodes of $\mathbf{H}$ when $\mathbf{P}$ is hierarchical. We then study the MacWilliams extension property (MEP) for $(\mathbf{P},\omega)$-weight. We show that the MEP implies the unique decomposition property (UDP) of $(\mathbf{P},\omega)$, which further implies that $\mathbf{P}$ is hierarchical if $\omega$ is identically $1$. For the case that either $\mathbf{P}$ is hierarchical or $\omega$ is identically $1$, we show that the MEP for $(\mathbf{P},\omega)$-weight can be characterized in terms of the MEP for Hamming weight, and give necessary and sufficient conditions for $\mathbf{H}$ to satisfy the MEP for $(\mathbf{P},\omega)$-weight when $S$ is an Artinian simple ring (either finite or infinite). When $S$ is a finite field, in the context of $(\mathbf{P},\omega)$-weight, we compare the MEP with other coding theoretic properties including the MacWilliams identity, Fourier-reflexivity of partitions and the UDP, and show that the MEP is strictly stronger than all the rest among them.

    Comment: arXiv admin note: text overlap with arXiv:2201.10828
    Keywords Computer Science - Information Theory
    Subject code 006
    Publishing date 2022-02-03
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Online: Reflexivity of Partitions Induced by Weighted Poset Metric and Combinatorial Metric

    Xu, Yang / Kan, Haibin / Han, Guangyue

    2022  

    Abstract: Let $\mathbf{H}$ be the Cartesian product of a family of finite abelian groups. Via a polynomial approach, we give sufficient conditions for a partition of $\mathbf{H}$ induced by weighted poset metric to be reflexive, which also become necessary for ... ...

    Abstract Let $\mathbf{H}$ be the Cartesian product of a family of finite abelian groups. Via a polynomial approach, we give sufficient conditions for a partition of $\mathbf{H}$ induced by weighted poset metric to be reflexive, which also become necessary for some special cases. Moreover, by examining the roots of the Krawtchouk polynomials, we establish non-reflexive partitions of $\mathbf{H}$ induced by combinatorial metric. When $\mathbf{H}$ is a vector space over a finite field $\mathbb{F}$, we consider the property of admitting MacWilliams identity (PAMI) and the MacWilliams extension property (MEP) for partitions of $\mathbf{H}$. With some invariance assumptions, we show that two partitions of $\mathbf{H}$ admit MacWilliams identity if and only if they are mutually dual and reflexive, and any partition of $\mathbf{H}$ satisfying the MEP is in fact an orbit partition induced by some subgroup of $\Aut_{\mathbb{F}}(\mathbf{H})$, which is necessarily reflexive. As an application of the aforementioned results, we establish partitions of $\mathbf{H}$ induced by combinatorial metric that do not satisfy the MEP, which further enable us to provide counter-examples to a conjecture proposed by Pinheiro, Machado and Firer in \cite{39}.
    Keywords Computer Science - Information Theory
    Subject code 006
    Publishing date 2022-01-26
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Online: Renyi Entropy Rate of Stationary Ergodic Processes

    Wu, Chengyu / Li, Yonglong / Xu, Li / Han, Guangyue

    2022  

    Abstract: In this paper, we examine the Renyi entropy rate of stationary ergodic processes. For a special class of stationary ergodic processes, we prove that the Renyi entropy rate always exists and can be polynomially approximated by its defining sequence; ... ...

    Abstract In this paper, we examine the Renyi entropy rate of stationary ergodic processes. For a special class of stationary ergodic processes, we prove that the Renyi entropy rate always exists and can be polynomially approximated by its defining sequence; moreover, using the Markov approximation method, we show that the Renyi entropy rate can be exponentially approximated by that of the Markov approximating sequence, as the Markov order goes to infinity. For the general case, by constructing a counterexample, we disprove the conjecture that the Renyi entropy rate of a general stationary ergodic process always converges to its Shannon entropy rate as {\alpha} goes to 1.
    Keywords Computer Science - Information Theory
    Publishing date 2022-07-15
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Book ; Online: The Langberg-M\'{e}dard Multiple Unicast Conjecture

    Cai, Kai / Han, Guangyue

    Stable $3$-Pair Networks

    2020  

    Abstract: The Langberg-M\'{e}dard multiple unicast conjecture claims that for a strongly reachable $k$-pair network, there exists a multi-flow with rate $(1,1,\dots,1)$. In this paper, we show that the conjecture holds true for {\em stable} $3$-pair networks. ...

    Abstract The Langberg-M\'{e}dard multiple unicast conjecture claims that for a strongly reachable $k$-pair network, there exists a multi-flow with rate $(1,1,\dots,1)$. In this paper, we show that the conjecture holds true for {\em stable} $3$-pair networks.
    Keywords Computer Science - Information Theory ; Mathematics - Combinatorics
    Publishing date 2020-01-07
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Expression of angiotensin converting enzyme 2 mRNA in different SARS-CoV-2 infection states and times.

    Guo, Nana / Li, Xue / Han, Zhanying / Yu, Qiuli / Zhang, Yanbo / Liu, Shiyou / Xu, Han / Han, Guangyue / Li, Qi

    Journal of biomolecular structure & dynamics

    2023  Volume 41, Issue 20, Page(s) 11255–11261

    Abstract: To measure the expression of angiotensin converting enzyme 2 (ACE2) mRNA in SARS-CoV-2 infection with different infection status and at different stages during infection, we used RT-qP CR to measure the expression of ACE2 mRNA. Measurements were analyzed ...

    Abstract To measure the expression of angiotensin converting enzyme 2 (ACE2) mRNA in SARS-CoV-2 infection with different infection status and at different stages during infection, we used RT-qP CR to measure the expression of ACE2 mRNA. Measurements were analyzed by two-way repeated measures analysis of variance (RMANOVA). Expression of ACE2 mRNA was downregulated in initial stages of SARS-CoV-2 infection both in the asymptomatic infection (ASY) group and the confirmed cases (CON) group (t=-8.0845, P < 0.0001; t=-8.1904, P < 0.0001, respectively). The expression of ACE2 mRNA in the incubation period of CON group was lower compared with the intinal period of ASY group (F = 6.084, p = 0.016, partialη2 = 0.070). Relative expression of ACE2 mRNA was upregulated at the late stage of SARS-CoV-2 infection in the ASY and CON groups (F = 23.489, p = 0.000, partialη2 = 0.225; F = 46.555, p = 0.000, partialη2 = 0.365, respectively). The relative expression of ACE2 mRNA was down-regulated (mean ± SEM:0.69 ± 0.03) after inoculation with SARSCoV- 2 Spike pseudovirus, and there was a statistical difference (one-way t test, mean diffience =-0.31, 95%CI: -0.37˜-0.24, t=-8.1904, P < 0.0001). The expression of ACE2 mRNA is downregulated in the initial stage of SARS-CoV-2 infection, and then upregulated in the late stage of SARS-CoV-2 infection. The lower expression of ACE2 mRNA during the incubation period can lead to clinical symptoms. Downregulation of ACE2 mRNA was related to the interaction between SARS-CoV-2 S protein and ACE2.Communicated by Ramaswamy H. Sarma.
    MeSH term(s) Humans ; COVID-19/genetics ; Angiotensin-Converting Enzyme 2/genetics ; SARS-CoV-2/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Peptidyl-Dipeptidase A/genetics ; Peptidyl-Dipeptidase A/metabolism
    Chemical Substances spike protein, SARS-CoV-2 ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) ; RNA, Messenger ; Peptidyl-Dipeptidase A (EC 3.4.15.1)
    Language English
    Publishing date 2023-01-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2022.2160821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: A New Proof of Hopf's Inequality Using a Complex Extension of the Hilbert Metric

    Han, Wendi / Han, Guangyue

    2019  

    Abstract: It is well known from the Perron-Frobenius theory that the spectral gap of a positive square matrix is positive. In this paper, we give a more quantitative characterization of the spectral gap. More specifically, using a complex extension of the Hilbert ... ...

    Abstract It is well known from the Perron-Frobenius theory that the spectral gap of a positive square matrix is positive. In this paper, we give a more quantitative characterization of the spectral gap. More specifically, using a complex extension of the Hilbert metric, we show that the so-called spectral ratio of a positive square matrix is upper bounded by its Birkhoff contraction coefficient, which in turn yields a lower bound on its spectral gap.
    Keywords Mathematics - Spectral Theory ; Computer Science - Information Theory
    Publishing date 2019-06-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Field Evaluation of a Duplex RT-RAA Assay for Rapid Detection of SARS-CoV-2 - Hebei Province, China, January 2021.

    Zhang, Ruiqing / Qi, Shunxiang / Li, Jiandong / Liu, Shiyou / Han, Guangyue / Shen, Xinxin / Li, Qi / Xu, Wenbo / Ma, Xuejun

    China CDC weekly

    2022  Volume 4, Issue 23, Page(s) 504–508

    Abstract: Introduction: Recently, a local cluster epidemic has occurred in Shijiazhuang City, Hebei Province. Failure to promptly identify patients with fever in rural areas was the major reason for this epidemic.: Methods: We presented the field evaluation of ...

    Abstract Introduction: Recently, a local cluster epidemic has occurred in Shijiazhuang City, Hebei Province. Failure to promptly identify patients with fever in rural areas was the major reason for this epidemic.
    Methods: We presented the field evaluation of a new real-time reverse transcription recombinase-aided amplification (RT-RAA) kit incorporating an endogenous internal control in a single-tube format, completed at the Hebei CDC from January 17, 2021 to January 27, 2021.
    Results: We evaluated the diagnostic performance of RT-RAA assay using automatic extracted RNA of 808 clinical samples. Compared with reverse transcriptase real-time quantitative PCR (qRT-PCR), RT-RAA kit achieved 92.41% sensitivity, 98.78% specificity and a 96.29% coincidence rate, demonstrating an excellent agreement between the RT-RAA assay and qRT-PCR assay. Furthermore, 58 samples were extracted using a manual extraction method within 5 minutes, but only samples with high nucleic acid concentration (cycle threshold value not higher than 32) could be stably detected.
    Discussion: The RT-RAA is more suitable to meet the needs of rapid, sensitive, and accurate detection in community-level medical institutions.
    Language English
    Publishing date 2022-05-19
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2022.111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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