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Article ; Online: Application and enlightenment of virtual reality technology in military psychological training

YU Weicheng / HAN Limin

陆军军医大学学报, Vol 45, Iss 23, Pp 2422-

2023 Volume 2427

Abstract: Virtual reality (VR), currently, as one of the most popular computer technologies, has shown a broad applied prospect. In this article, we review the concept and technical features of VR, and summarize its application in the field of military ... ...

Abstract	Virtual reality (VR), currently, as one of the most popular computer technologies, has shown a broad applied prospect. In this article, we review the concept and technical features of VR, and summarize its application in the field of military psychological training: psychological relaxation training, cognitive training, psychological resilience training, extraordinary psychological training, post-traumatic growth training, psychological experiment and monitoring and suicide-preventing communication training. We also propose that in the future, we should strengthen our military psychological training based on VR in terms of theory, technology, and knowledge dissemination.
Keywords	virtual reality ; military psychological training ; application ; post-traumatic stress disorder ; Medicine (General) ; R5-920
Language	Chinese
Publishing date	2023-12-01T00:00:00Z
Publisher	Editorial Office of Journal of Army Medical University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Intervention study on enhancing well-being of freshmen in military universities based on Wechat platform

HAN Limin / PENG Fan / SONG Weiwei

陆军军医大学学报, Vol 45, Iss 23, Pp 2428-

2023 Volume 2433

Abstract: Objective To explore the efficacy of Wechat platform-based positive psychology intervention on the well-being in freshmen in military universities. Methods Two stages of experiments were carried out. In the first stage, 67 cadets were subjected from the ... ...

Abstract	Objective To explore the efficacy of Wechat platform-based positive psychology intervention on the well-being in freshmen in military universities. Methods Two stages of experiments were carried out. In the first stage, 67 cadets were subjected from the classroom teaching class of a military university by cluster sampling, and were assigned into an experimental group (n=30) and a control group (n=37) according to their own willing. The participants of the experimental group were asked to follow WeChat official account "Happiness Promotion Training Camp" and write records of "mindfulness meditation", "putting complaints aside" and "three good things" every day, but those of the control group had no such interventions. In the second stage, 161 cadets were sampled as above and autonomously divided into experimental group (n=74) and the control group (n=87). The experimental group followed the official account "Happiness Promotion Training Camp" and recorded "three good things" every day, and the other group received no such intervention. In both stages, Miao Yuanjiang's Multiple Happiness questionnaire (MHQ) was used to evaluate the participants of the 2 groups before and after intervention. Results ① In the first stage, after 4 weeks, the experimental group got significantly higher well-being than the control group, mainly in the dimensions of life satisfaction, health concern and self-worth. ② In the second stage, there was no significant difference in the increase of well-being between the experimental group and the control group after 8 weeks. It may be related to the matching of intervention activities and target groups, the subjects' motivation and the simplicity of intervention activities. Conclusion WeChat platform-based comprehensive positive psychology intervention can improve the well-being of cadets, but the effect of single psychological intervention is not good.
Keywords	cadets ; positive psychology interventions ; wechat platform ; well-being ; Medicine (General) ; R5-920
Subject code	796
Language	Chinese
Publishing date	2023-12-01T00:00:00Z
Publisher	Editorial Office of Journal of Army Medical University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genome-Wide Identification and Expression Analysis of the MYB Transcription Factor Family in

Yang, Huan / Chen, Chen / Han, Limin / Zhang, Xiao / Yue, Ming

Genes

2024 Volume 15, Issue 1

Abstract: The MYB transcription factor gene family is among the most extensive superfamilies of transcription factors in plants and is involved in various essential functions, such as plant growth, defense, and pigment formation. ...

Abstract	The MYB transcription factor gene family is among the most extensive superfamilies of transcription factors in plants and is involved in various essential functions, such as plant growth, defense, and pigment formation.
MeSH term(s)	Transcription Factors/genetics ; Salvia/genetics ; Anthocyanins/genetics ; Phylogeny ; Plant Breeding
Chemical Substances	Transcription Factors ; Anthocyanins
Language	English
Publishing date	2024-01-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes15010110
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Nussbaum-Based Adaptive Fault-Tolerant Control for Nonlinear CPSs With Deception Attacks: A New Coordinate Transformation Technology.

Chen, Wen-Di / Li, Yuan-Xin / Liu, Lei / Zhao, Xu-Dong / Niu, Ben / Han, Li-Min

IEEE transactions on cybernetics

2024 Volume 54, Issue 2, Page(s) 1212–1222

Abstract: In this article, two novel adaptive fault-tolerant control schemes for a class of nonlinear strict-feedback cyber-physical systems (CPSs) with deception attacks are presented. Deception attacks, such as false data-injection attacks, which destroy sensor ... ...

Abstract	In this article, two novel adaptive fault-tolerant control schemes for a class of nonlinear strict-feedback cyber-physical systems (CPSs) with deception attacks are presented. Deception attacks, such as false data-injection attacks, which destroy sensor networks, make the outputs and states of the CPSs unavailable. It is very difficult and challenging for a designer to achieve the tracking control under the circumstance of cyberattacks. To realize the tracking control for the studied CPSs, we propose a new coordinate transformation technology without precedent, where it takes the attack gains into account and uses the compromised states to design the corresponding controllers. In the backstepping design process, Nussbaum functions are presented to alleviate the influence of the unknown attack gains. Furthermore, we consider the actuator faults problem, which includes the loss of effectiveness and the bias fault. By skillfully designing the adaptive laws, the effect of actuator faults is completely eliminated. It is theoretically proved that the first proposed tracking control scheme can guarantee all signals in the closed-loop system are bounded and the output can track the desired reference signal. In addition, the second adaptive control scheme is also developed for the CPSs under the actuator faults and a more general assumption on the deception attacks is proposed simultaneously. Finally, the feasibility of the new proposed methods is verified by MATLAB simulation analysis.
Language	English
Publishing date	2024-01-17
Publishing country	United States
Document type	Journal Article
ISSN	2168-2275
ISSN (online)	2168-2275
DOI	10.1109/TCYB.2022.3206861
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Article ; Online: Economic Growth Prediction Algorithm of Coastal Area Based on Impulse Response Function

Qiu Rong-Shan / Ding Ding / Han Li-Min

Security and Communication Networks, Vol

2021 Volume 2021

Abstract: In order to solve the problems of low accuracy and long prediction time of traditional economic growth prediction algorithms in coastal areas, an algorithm based on impulse response function was designed to analyze economic growth prediction in coastal ... ...

Abstract	In order to solve the problems of low accuracy and long prediction time of traditional economic growth prediction algorithms in coastal areas, an algorithm based on impulse response function was designed to analyze economic growth prediction in coastal areas. Crawler technology is used to capture the economic data of coastal areas and normalize the captured data. Based on the processed data, the impulse response function is used to analyze the relationship between different economic variables, so as to build the PSO-LSTM model, which is used to predict the economic growth trend of coastal areas. The experimental results show that, compared with the experimental comparison algorithm, the prediction accuracy of the algorithm designed in this paper is always above 97%, and the prediction time is always below 1 s, which has certain practical significance.
Keywords	Technology (General) ; T1-995 ; Science (General) ; Q1-390
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Catalyst-free reductive cyclization of bis(2-aminophenyl) disulfide with CO

Li, Xiao / Liu, Zhenbao / Hong, Hailong / Han, Limin / Zhu, Ning

RSC advances

2022 Volume 12, Issue 28, Page(s) 18107–18114

Abstract: An efficient and catalyst-free methodology for the reductive cyclization of various disulfides using ... ...

Abstract	An efficient and catalyst-free methodology for the reductive cyclization of various disulfides using BH
Language	English
Publishing date	2022-06-20
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d2ra03134e
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Article ; Online: Analysis on the structure effect of marine fishery total factor productivity under high-quality development in China.

Wang, Bo / Han, Limin / Zhang, Hongzhi

PloS one

2021 Volume 16, Issue 11, Page(s) e0259853

Abstract: Improving total factor productivity (TFP) is the source of power for high-quality development. Industrial structure optimization is an important way to improve TFP. This paper constructed an econometric model of industry structure changes impacting on ... ...

Abstract	Improving total factor productivity (TFP) is the source of power for high-quality development. Industrial structure optimization is an important way to improve TFP. This paper constructed an econometric model of industry structure changes impacting on TFP in the marine fisheries and conducted an empirical test and analysis. The results showed that the industry rationalization, softening and processing coefficient of marine fishery had a significant "structural dividend" for improving its TFP; while the impact of industrial structure advancement and aquaculture-catching structure changes did not have "structural dividend", but it could be a combination of other factors to reduce these adverse effects.We believe that simply pursuing the advanced evolution of the industrial structure is not conducive to sustainable development of fishery. Under the pursuit of the rationalization of the marine fishery industry structure, by promoting the coordinated evolution of marine fisheries advancement, aquaculture-catching structure and other factors, the "structural dividend" effect can be enhanced and the fishery can achieve sustainable development. Finally, it proposed to promote the development of advancement and rationalization of marine fishery industry structure coordinately, adjust fishery science and technology transformation direction and key points, and accelerate the development of intensive processing industry by cross-border integration.
MeSH term(s)	Animals ; Aquaculture/economics ; Aquaculture/methods ; China ; Conservation of Natural Resources/methods ; Fisheries/trends ; Humans ; Industry/methods ; Manufacturing Industry ; Models, Econometric ; Rationalization ; Sustainable Development/trends ; Technology
Language	English
Publishing date	2021-11-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0259853
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Article ; Online: Spatial Differences of Nutrient Adequacy in Coastal Areas of China.

Yin, Wei / Yu, Huijuan / Wang, Yecheng / Qiu, Rongshan / Han, Limin

Nutrients

2022 Volume 14, Issue 22

Abstract: Ensuring nutrient adequacy for all is a common goal of the international community, but spatial difference is one of the barriers to its development. Exploring nutrient adequacy in coastal areas of China can help regions where food production systems and ...

Abstract	Ensuring nutrient adequacy for all is a common goal of the international community, but spatial difference is one of the barriers to its development. Exploring nutrient adequacy in coastal areas of China can help regions where food production systems and economic development systems are under mutual stress to reduce nutritional disparities and improve nutrition levels. This paper used the transformation food-to-nutrient model to calculate nutrient production and nutrient consumption in 11 coastal provinces of China and analyzed their spatial patterns, after which spatial differences in nutrient adequacy (including energy, protein and fat) were analyzed. The results showed that nutrient production and nutrient consumption in coastal areas of China showed significant spatial differences, in which nutrient production was mainly concentrated in land food, and the three provinces of Shandong, Jiangsu and Hebei contributed more. Guangdong had the highest nutrient consumption; in contrast, Shanghai, Tianjin, and Hainan had the lowest consumption. Nutrient adequacy was not optimistic, with fat being particularly significant, and nutrient surplus quantity was mainly concentrated in Shandong and Jiangsu and nutrient deficiency quantity was mainly concentrated in Guangdong. Overall, the study area had adequate levels of protein and was deficient in energy and fat levels, with surplus or shortage of 2.41 million tonnes, 2620 billion kcal and 9.97 million tonnes, respectively.
MeSH term(s)	China ; Nutrients
Language	English
Publishing date	2022-11-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14224763
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Article ; Online: Arenobufagin inhibits lung metastasis of colorectal cancer by targeting c-MYC/Nrf2 axis.

Wang, Mei / Hu, Siyi / Yang, Jiawang / Yuan, Liang / Han, Limin / Liang, Feng / Zhang, Fenglin / Zhao, Hailong / Liu, Yun / Gao, Ning

Phytomedicine : international journal of phytotherapy and phytopharmacology

2024 Volume 127, Page(s) 155391

Abstract: Background: Colorectal cancer (CRC) is one of the commonest cancers worldwide. Metastasis is the most common cause of death in patients with CRC. Arenobufagin is an active component of bufadienolides, extracted from toad skin and parotid venom. ... ...

Abstract	Background: Colorectal cancer (CRC) is one of the commonest cancers worldwide. Metastasis is the most common cause of death in patients with CRC. Arenobufagin is an active component of bufadienolides, extracted from toad skin and parotid venom. Arenobufagin reportedly inhibits epithelial-to-mesenchymal transition (EMT) and metastasis in various cancers. However, the mechanism through which arenobufagin inhibits CRC metastasis remains unclear. Purpose: This study aimed to elucidate the molecular mechanisms by which arenobufagin inhibits CRC metastasis. Methods: Wound-healing and transwell assays were used to assess the migration and invasion of CRC cells. The expression of nuclear factor erythroid-2-related factor 2 (Nrf2) in the CRC tissues was assessed using immunohistochemistry. The protein expression levels of c-MYC and Nrf2 were detected by immunoblotting. A mouse model of lung metastasis was used to study the effects of arenobufagin on CRC lung metastasis in vivo. Results: Arenobufagin observably inhibited the migration and invasion of CRC cells by downregulating c-MYC and inactivating the Nrf2 signaling pathway. Pretreatment with the Nrf2 inhibitor brusatol markedly enhanced arenobufagin-mediated inhibition of migration and invasion, whereas pretreatment with the Nrf2 agonist tert‑butylhydroquinone significantly attenuated arenobufagin-mediated inhibition of migration and invasion of CRC cells. Furthermore, Nrf2 knockdown with short hairpin RNA enhanced the arenobufagin-induced inhibition of the migration and invasion of CRC cells. Importantly, c-MYC acts as an upstream modulator of Nrf2 in CRC cells. c-MYC knockdown markedly enhanced arenobufagin-mediated inhibition of the Nrf2 signaling pathway, cell migration, and invasion. Arenobufagin inhibited CRC lung metastasis in vivo. Together, these findings provide evidence that interruption of the c-MYC/Nrf2 signaling pathway is crucial for arenobufagin-inhibited cell metastasis in CRC. Conclusions: Collectively, our findings show that arenobufagin could be used as a potential anticancer agent against CRC metastasis. The arenobufagin-targeted c-MYC/Nrf2 signaling pathway may be a novel chemotherapeutic strategy for treating CRC.
MeSH term(s)	Animals ; Mice ; Humans ; NF-E2-Related Factor 2/metabolism ; Colorectal Neoplasms/pathology ; Cell Line, Tumor ; Bufanolides/pharmacology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Epithelial-Mesenchymal Transition ; Cell Movement ; Gene Expression Regulation, Neoplastic ; Cell Proliferation ; Neoplasm Metastasis
Chemical Substances	arenobufagin (464-74-4) ; NF-E2-Related Factor 2 ; Bufanolides
Language	English
Publishing date	2024-02-21
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2024.155391
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Article ; Online: Anemonin ameliorates human diploid fibroblasts 2BS and IMR90 cell senescence by PARP1-NAD

Zhao, Lijun / Hu, Kexin / Liu, Weiting / Qi, Haonan / Li, Guodong / Chen, Jun / Han, Limin

Archives of gerontology and geriatrics

2023 Volume 117, Page(s) 105255

Abstract: Objective: Aging becomes the most predominant risk factor for all age-associated pathological conditions with the increase of life expectancy and the aggravation of social aging. Slowing down the speed of aging is considered an effective way to improve ... ...

Abstract	Objective: Aging becomes the most predominant risk factor for all age-associated pathological conditions with the increase of life expectancy and the aggravation of social aging. Slowing down the speed of aging is considered an effective way to improve health, but so far, effective anti-aging methods are relatively lacking. Methods: Anemonin (ANE) was screened from eight existing small-molecule compounds by cell viability assay. The function of ANE was determined by the analysis of cell proliferation, β -galactosidase (SA-β -Gal) activity, cell cycle, SASP secretion, NAD Results: ANE can delay cell senescence; PARP1 is one of the targets of ANE and plays a crucial role in ANE anti-aging; ANE release more NAD Conclusions: Our study indicates that ANE can delay cellular senescence through the PARP1-NAD
MeSH term(s)	Humans ; Sirtuin 1/genetics ; Sirtuin 1/metabolism ; Sirtuin 1/pharmacology ; NAD/metabolism ; NAD/pharmacology ; Diploidy ; Cellular Senescence/physiology ; Signal Transduction ; Fibroblasts/metabolism ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Poly (ADP-Ribose) Polymerase-1/pharmacology
Chemical Substances	Sirtuin 1 (EC 3.5.1.-) ; NAD (0U46U6E8UK) ; anemonin (G99XG5B674) ; SIRT1 protein, human (EC 3.5.1.-) ; PARP1 protein, human (EC 2.4.2.30) ; Poly (ADP-Ribose) Polymerase-1 (EC 2.4.2.30)
Language	English
Publishing date	2023-10-31
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603162-6
ISSN	1872-6976 ; 0167-4943
ISSN (online)	1872-6976
ISSN	0167-4943
DOI	10.1016/j.archger.2023.105255
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