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  1. Article: Opportunistic Eye Screening Among First-Degree Relatives of Glaucoma Patients at a Suburban Tertiary Center in Malaysia.

    Chelvaraj, Radtthiga / Hanapi, Maya Sapira / Mohd-Yusof, Siti-Fairuz / Sonny Teo, Khairy Shamel / Ahmad Tajudin, Liza Sharmini / Yaakub, Azhany

    Cureus

    2022  Volume 14, Issue 6, Page(s) e25772

    Abstract: Background and objective The majority of glaucoma patients are asymptomatic and are usually diagnosed at an advanced stage of the disease. This study aimed to assess the outcomes of glaucoma screening among known first-degree relatives of primary ... ...

    Abstract Background and objective The majority of glaucoma patients are asymptomatic and are usually diagnosed at an advanced stage of the disease. This study aimed to assess the outcomes of glaucoma screening among known first-degree relatives of primary glaucoma patients. Materials and methods This study involved primary angle-closure glaucoma (PACG), primary open-angle glaucoma (POAG), and juvenile open-angle glaucoma (JOAG) patients who attended the glaucoma clinic at the Hospital Universiti Sains Malaysia between January 2014 and December 2015. First-degree relatives of the patients underwent a preliminary eye-screening evaluation, including visual acuity (Snellen chart), intraocular pressure (IOP) measurement (air-puff tonometry), and non-mydriatic fundus photography. Patients with visual acuity worse than 6/12, IOP measuring more than 21 mmHg or a difference of more than 3 mmHg between the eyes, and a vertical cup-disc ratio (VCDR) of 0.7 or higher were given a comprehensive eye examination. Results Seventy indexed glaucoma patients were recognized, and 368 first-degree relatives were identified. Forty-five relatives underwent the preliminary screening. Of these, 29 showed normal findings (62%), one had corneal pathology (2%), and 16 (36%) underwent a complete eye examination after failing the initial screening. Among the indexed JOAG group, five relatives (11%) were diagnosed as having JOAG; two were treated medically, while the remaining three required surgical intervention. Conclusion Opportunistic glaucoma screening of high-risk groups, especially JOAG is a feasible and cost-effective way to detect early glaucoma and prevent irreversible blindness. However, improvement in our healthcare system, including the involvement of multicentre clinics in other states in screening initiatives, is required to promote and facilitate the response to screening opportunities.
    Language English
    Publishing date 2022-06-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.25772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Bilateral and Multiple Central Serous Chorioretinopathy Following COVID-19 Infection: A Case Report and Literature Review.

    Mohd-Alif, W Mohd / Nur-Athirah, Adnan / Hanapi, Maya Sapira / Tuan Jaffar, Tengku Norina / Shatriah, Ismail

    Cureus

    2022  Volume 14, Issue 3, Page(s) e23246

    Abstract: Central serous chorioretinopathy (CSCR) following coronavirus disease 2019 (COVID-19) infection is rare. We describe an adult patient who survived a COVID-19 infection and received intravenous and oral corticosteroid treatment for three weeks. He ... ...

    Abstract Central serous chorioretinopathy (CSCR) following coronavirus disease 2019 (COVID-19) infection is rare. We describe an adult patient who survived a COVID-19 infection and received intravenous and oral corticosteroid treatment for three weeks. He presented three weeks post COVID-19 infection with central visual loss in both eyes for six days. Fundus examination showed multiple localized serous retinal detachments in both eyes. Optical coherence tomography (OCT) of the macula confirmed the presence of multiple areas of serous retinal detachment and pigment epithelial detachment. The patient was treated with topical non-steroidal anti-inflammatory eye drops and regained full visual recovery after three months. Corticosteroid treatment for COVID-19 and psychological stress induced by the disease are potential risk factors for the development of CSCR. Physicians should be aware of this side effect, as an early referral to an ophthalmologist for treatment is essential.
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.23246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Extensive Forehead Swelling Including the Periorbital Area in a Child: A Rare Manifestation of Acute Lymphoblastic Leukemia.

    Hanapi, Maya Sapira / Ghani, Siti-Ilyana / Sonny Teo, Khairy Shamel / Wan-Embong, Wan-Zuhairah / Ariffin, Nasir / Wan Hitam, Wan-Hazabbah

    Cureus

    2018  Volume 10, Issue 11, Page(s) e3539

    Abstract: Acute lymphoblastic leukemia (ALL) manifestations in a child are varied. We report a unique and rare presentation of acute lymphoblastic leukemia in a child who presented with frontal swelling involving bilateral upper lids. A previously healthy one-year- ...

    Abstract Acute lymphoblastic leukemia (ALL) manifestations in a child are varied. We report a unique and rare presentation of acute lymphoblastic leukemia in a child who presented with frontal swelling involving bilateral upper lids. A previously healthy one-year-old girl presented with progressively increasing frontal swelling of seven months duration. An examination revealed erythematous, firm, nontender forehead swelling that extended up to the medial part of bilateral upper eye lids. The extraocular muscle movement was normal. The anterior segment and fundus examination were also normal in both eyes. Other systemic examination revealed multiple leukemic cutis on the scalp. The cervical lymph nodes were also palpable with hepatosplenomegaly. A full blood picture (FBP) showed the presence of leucoerythroblastic blood film with 62% blast cells. Flow cytometry and bone marrow aspiration confirmed the diagnosis. Computed tomographic (CT) scan images revealed multiple well-defined hyperdense lesions at the subcutaneous skull with the largest lesion at the anterior glabella. Upon diagnosis, the patient was started on chemotherapy and the swelling resolved after one month post treatment. Extensive forehead swelling is a rare manifestation of acute lymphoblastic leukemia. A high index of suspicion aided with diagnostic investigations could help the doctors arrive at a correct diagnosis and treatment.
    Language English
    Publishing date 2018-11-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.3539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Endophthalmitis following cataract surgery in diabetic patients

    Hanapi Maya-Sapira / Yi-Ni Koh / Yaakub Azhany / Embong Zunaina / Sonny-Teo Khairy-Shamel / Ahmad Tajuddin Liza-Sharmini / Nani Draman / Zamri Noordin

    Family Medicine & Primary Care Review, Vol 19, Iss 4, Pp 431-

    2017  Volume 436

    Abstract: Background . Endophthalmitis post cataract surgery is rare, but the incidence and complications are higher in diabetics. Objectives . We present 3 diabetic patients who underwent cataract surgery and developed endophthalmitis postoperatively. Material ... ...

    Abstract Background . Endophthalmitis post cataract surgery is rare, but the incidence and complications are higher in diabetics. Objectives . We present 3 diabetic patients who underwent cataract surgery and developed endophthalmitis postoperatively. Material and methods . This is a retrospective case series of diabetic patients who underwent cataract surgery and developed endophthalmitis postoperatively between September 2015 and August 2016. The medical records were retrieved from the system, and data was collected. Results . The patients eventually had different visual outcomes depending on the severity of endophthalmitis. Case 1. The patient developed delayed subtle postoperative endophthalmitis at 8 weeks post cataract operation, with underlying foot cellulitis and poor blood sugar control. The patient responded well to topical and systemic antibiotics and stabilization of blood sugar. Case 2. The patient presented with delayed postoperative endophthalmitis secondary to a suture abscess of the cataract wound at 7 months post implantation of an anterior chamber intraocular lens. There was complete resolution of the infection after administration of topical, intravitreal and systemic antibiotics, with a good control of blood sugar. Case 3. The patient presented with acute severe postoperative endophthalmitis with the presence of hypopyon at day 5 following cataract surgery. There were no obvious risk factors besides poor control of blood sugar, but Streptococcus mitis was isolated from the vitreous specimen. The endophthalmitis worsened in spite of topical, intravitreal and systemic antibiotics, as well as vitrectomy. Evisceration was eventually performed for the painful blind eye. Conclusions . Although endophthalmitis following cataract surgery is rare, the incidence and complications are much higher in diabetic patients.
    Keywords endophthalmitis ; cataract surgery ; diabetes mellitus ; Streptococcus mitis ; Medicine ; R
    Subject code 616 ; 610
    Language English
    Publishing date 2017-12-01T00:00:00Z
    Publisher Continuo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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