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Book ; Online: Distant Companions

Hansen, Karen Tranberg

Servants and Employers in Zambia, 1900-1985

2018

Keywords	Social & cultural anthropology, ethnography ; Social & cultural anthropology
Language	English
Size	1 electronic resource (342 pages)
Publisher	Cornell University Press
Document type	Book ; Online
Note	English
HBZ-ID	HT030721780
ISBN	9781501719967 ; 1501719963
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Concerns about Race and Ethnicity within the United States Fracture Risk Assessment Tool.

Mayer, Martin / Keevil, Jon / Hansen, Karen E

Journal of bone metabolism

2022 Volume 29, Issue 2, Page(s) 141–144

Language	English
Publishing date	2022-05-31
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2765291-9
ISSN	2287-7029 ; 2287-6375
ISSN (online)	2287-7029
ISSN	2287-6375
DOI	10.11005/jbm.2022.29.2.141
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Article ; Online: Mesh exposure following minimally invasive sacrocolpopexy: a narrative review.

Deblaere, Stephanie / Hauspy, Jan / Hansen, Karen

International urogynecology journal

2022 Volume 33, Issue 10, Page(s) 2713–2725

Abstract: Introduction and hypothesis: Sacrocolpopexy is considered mainstay treatment for apical or vaginal vault prolapse and is currently most often performed via a minimally invasive approach. Although mesh-related complications after this procedure are ... ...

Abstract	Introduction and hypothesis: Sacrocolpopexy is considered mainstay treatment for apical or vaginal vault prolapse and is currently most often performed via a minimally invasive approach. Although mesh-related complications after this procedure are uncommon, mesh exposure can have an important impact on the patient's quality of life. Our objective is to perform a literature review on this complication post laparoscopic or robotic sacrocolpopexy. Methods: Web of Science and MEDLINE databases were searched for relevant articles published between 2005 and 2021. We retrieved 272 articles of which 83 ultimately were withheld. Results: Minimally invasive sacrocolpopexy (MISC) implies a low risk of mesh exposure, which is currently estimated at 3.5%. Literature however is marked by substantial methodological heterogeneity. Controversy remains in the debate over prevention of mesh exposure after MISC. Performing a concomitant total hysterectomy is associated with an increased risk compared to subtotal hysterectomy or hysteropexy. Treatment of mesh exposure is challenging as guidelines are lacking. Although supported by few prospective data, patients with asymptomatic mesh exposure are managed conservatively. Surgical intervention, preferentially performed by an experienced pelvic surgeon, is indicated in symptomatic patients. Conclusions: Mesh exposure is often undiagnosed and remains untreated. There is a gap in evidence exploring risk factors for mesh-related complications and efficient measures for reducing them. Choosing the best treatment option is still difficult. Management should be individualized and optimized at the time of diagnosis. Lack of acknowledgement and experience can result in increased morbidity.
MeSH term(s)	Female ; Gynecologic Surgical Procedures/adverse effects ; Gynecologic Surgical Procedures/methods ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Pelvic Organ Prolapse/etiology ; Pelvic Organ Prolapse/surgery ; Prospective Studies ; Quality of Life ; Surgical Mesh/adverse effects ; Treatment Outcome ; Vagina/surgery
Language	English
Publishing date	2022-02-28
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1050631-7
ISSN	1433-3023 ; 0937-3462
ISSN (online)	1433-3023
ISSN	0937-3462
DOI	10.1007/s00192-021-04998-2
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Book ; Online: Distant Companions

Hansen, Karen Tranberg

Servants and Employers in Zambia, 1900-1985

(The Anthropology of Contemporary Issues Ser)

2018

Abstract: Distant Companions -- Contents -- Preface -- Abbreviations -- Introduction: The Problem and Its Context -- Part I A Fixture of Colonial Society -- 1. The Creation of a Gender Role: The Male Domestic Servant -- 2. Women for Hire? Sex and Gender in ... ...

Series title	The Anthropology of Contemporary Issues Ser
Abstract	Distant Companions -- Contents -- Preface -- Abbreviations -- Introduction: The Problem and Its Context -- Part I A Fixture of Colonial Society -- 1. The Creation of a Gender Role: The Male Domestic Servant -- 2. Women for Hire? Sex and Gender in Domestic Service -- 3. Troubled Lives: Servants and Their Employers in the Preindependence Era -- Part II Encountering Domestic Service -- 4. Research on and Life with Servants -- Part III Colonial Legacies and Postcolonial Changes -- 5. Persistence and Change -- 6. A Transformed Occupation -- 7. Lives beyond the Workplace -- 8. Servants Everywhere: Conclusions -- Appendix 1 Servants' Wages -- Appendix 2 Servants' Budgets -- Index
Language	English
Size	1 Online-Ressource (340 pages)
Document type	Book ; Online
ISBN	9781501719950 ; 9781501719967 ; 9781501719967 ; 1501719955 ; 1501719963 ; 1501719963
Database	ECONomics Information System

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Article ; Online: Denosumab in the treatment of glucocorticoid-induced osteoporosis: a systematic review and meta-analysis.

Yanbeiy, Zeina A / Hansen, Karen E

Drug design, development and therapy

2019 Volume 13, Page(s) 2843–2852

Abstract: Objective: Glucocorticoid-induced osteoporosis (GIOP) is the most common form of secondary osteoporosis. In May 2018, denosumab was approved for the treatment of GIOP in men and women at high risk of fracture. We undertook a systematic review and meta- ... ...

Abstract	Objective: Glucocorticoid-induced osteoporosis (GIOP) is the most common form of secondary osteoporosis. In May 2018, denosumab was approved for the treatment of GIOP in men and women at high risk of fracture. We undertook a systematic review and meta-analysis to summarize the efficacy and safety of denosumab in the prevention and treatment of GIOP. Methods: We searched PubMed, CINAHL, American College of Rheumatology and American Society for Bone and Mineral Research meeting abstracts for relevant studies. We included studies in which subjects were taking systemic glucocorticoid therapy and were assigned to take denosumab or control therapy, and assessed the effect of treatment on areal bone mineral density (BMD), fractures and/or safety. Results: Three eligible studies were included in the primary meta-analysis. Denosumab significantly increased lumbar spine BMD (2.32%, 95% CI 1.73%, 2.91%, Conclusion: Results suggest that denosumab is superior to bisphosphonates in its effects on lumbar spine and total hip BMD in patients with GIOP. There was no difference in the incidence of infections, adverse events or serious adverse events. Studies were underpowered to detect differences in the risk of fracture. Denosumab is a reasonable option for treatment of GIOP. However, further studies are needed to guide transitions off denosumab.
MeSH term(s)	Denosumab/therapeutic use ; Female ; Glucocorticoids/therapeutic use ; Humans ; Osteoporosis/chemically induced ; Osteoporosis/drug therapy
Chemical Substances	Glucocorticoids ; Denosumab (4EQZ6YO2HI)
Language	English
Publishing date	2019-08-14
Publishing country	New Zealand
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2451346-5
ISSN	1177-8881 ; 1177-8881
ISSN (online)	1177-8881
ISSN	1177-8881
DOI	10.2147/DDDT.S148654
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Article ; Online: Sjögren's disease activity associates with cardiovascular disease and monoclonal gammopathy: a university cohort study of disease activity and comorbidities.

Bohman, Bradley R / Dowds, Hunter S / Blagogee, Temisan E / Ike, Robert W / Hansen, Karen E / McCoy, Sara S

Clinical rheumatology

2024 Volume 43, Issue 3, Page(s) 1093–1101

Abstract: Background: We used the University of Wisconsin cohort to determine the extent to which the EULAR Sjögren's syndrome disease activity index (ESSDAI) was associated with comorbidities that contribute to mortality.: Methods: Our University of Wisconsin, ...

Abstract	Background: We used the University of Wisconsin cohort to determine the extent to which the EULAR Sjögren's syndrome disease activity index (ESSDAI) was associated with comorbidities that contribute to mortality. Methods: Our University of Wisconsin, Madison cohort had 111 patients with Sjögren's Disease (SjD) by 2016 ACR/EULAR criteria and 194 control patients with sicca. Our study was performed from March 1st, 2020 through April 1st, 2023. We collected data using a standardized collection tool, including components of the Charlson Comorbidity Index (CCI). Stratifying our SjD patients by ESSDAI < 5 and ESSDAI ≥ 5, we assessed differences in comorbidities associated with mortality. Results: At time of SjD diagnosis, the ESSDAI ≥ 5 group had increased odds of peripheral vascular disease compared to controls (OR 10.17; 95% CI 1.18-87.87). Patients with a current ESSDAI ≥ 5 were more likely to have a myocardial infarction compared to controls (OR 9.87; 95% CI 1.17-83.49). SjD patients had increased prevalence of monoclonal gammopathy compared to controls (9.3% vs 0.5%, p < 0.001). SjD patients with high ESSDAI at diagnosis had greater prevalence of monoclonal gammopathy compared to the SjD patients with a low ESSDAI (16% vs 5%, p = .04). As reported elsewhere, the ESSDAI ≥ 5 group had increased odds of chronic pulmonary disease (OR 4.37; 95% CI 1.59-11.97). Conclusion: We found high ESSDAI scores were associated with worse cardiovascular outcomes, specifically peripheral vascular disease and myocardial infarction. Furthermore, monoclonal gammopathy was more frequent in SjD patients compared to sicca controls, supporting screening for monoclonal gammopathy in the appropriate clinical scenario. Key Points • High ESSDAI scores are associated with worse cardiovascular outcomes, specifically peripheral vascular disease and myocardial infarction. • Monoclonal gammopathy is more frequent in SjD patients than sicca controls, supporting screening for monoclonal gammopathy in the appropriate clinical scenario.
MeSH term(s)	Humans ; Sjogren's Syndrome/complications ; Sjogren's Syndrome/epidemiology ; Sjogren's Syndrome/diagnosis ; Cohort Studies ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/epidemiology ; Universities ; Severity of Illness Index ; Comorbidity ; Paraproteinemias/complications ; Paraproteinemias/epidemiology ; Monoclonal Gammopathy of Undetermined Significance/complications ; Monoclonal Gammopathy of Undetermined Significance/epidemiology ; Myocardial Infarction ; Peripheral Vascular Diseases
Language	English
Publishing date	2024-02-07
Publishing country	Germany
Document type	Journal Article
ZDB-ID	604755-5
ISSN	1434-9949 ; 0770-3198
ISSN (online)	1434-9949
ISSN	0770-3198
DOI	10.1007/s10067-024-06890-y
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Article ; Online: Women's experiences of induction of labour with misoprostol tablets compared with vaginal insert.

Hansen, Karen H / Eriksson, Axelina / Jeppesen, Sarah / Jeppegaard, Maria / Krebs, Lone

Danish medical journal

2023 Volume 70, Issue 2

Abstract: Introduction: The aim of this study was to compare nulliparous women's experiences with induction of labour using two different regimens of misoprostol.: Methods: We adapted a validated questionnaire regarding experience with induced labour. In two ... ...

Abstract	Introduction: The aim of this study was to compare nulliparous women's experiences with induction of labour using two different regimens of misoprostol. Methods: We adapted a validated questionnaire regarding experience with induced labour. In two different hospitals, 123 women undergoing medical induction of labour completed a questionnaire after delivery. An independent-samples T-test was used for comparison of parametric continuous variables and Pearson's χ2 test was used for categorical data. The two groups differed regarding BMI and pregnancy complications. No adjusted estimates were calculated. Results: Women induced with oral misoprostol experienced more painful induction of labour (p = 0.019) and described feeling that their length of stay at hospital was excessive (p = 0.028). Overall, the experience of giving birth after induction of labour was reported as "good" among 87.8% of women induced with oral misoprostol compared with 72.7% of the women induced with a slow-release misoprostol vaginal insert (p = 0.039). Conclusion: In two departments characterized by several differences, including whether vaginal or oral misoprostol was used, induction with oral misoprostol in an out-patient setting was associated with a better experience of labour than induction with a slow-release misoprostol vaginal insert. Funding: Region Zealand Health Scientific Research Foundation supported the study financially. Trial registration: The study was registered with clinicaltrials.gov ID: NCT02693587 on 26 February 2016 and with EudraCT number 2020-000366-42 on 23 January 2020 (retrospectively registered).
MeSH term(s)	Female ; Humans ; Pregnancy ; Labor, Induced ; Misoprostol ; Oxytocics/adverse effects ; Tablets ; Vagina
Chemical Substances	Misoprostol (0E43V0BB57) ; Oxytocics ; Tablets
Language	English
Publishing date	2023-01-24
Publishing country	Denmark
Document type	Clinical Trial ; Comparative Study ; Journal Article
ZDB-ID	2648771-8
ISSN	2245-1919 ; 2245-1919
ISSN (online)	2245-1919
ISSN	2245-1919
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Confirmatory digital subtraction angiography after clinical brain death/death by neurological criteria: impact on number of donors and organ transplants.

Hansen, Karen Irgens Tanderup / Kelsen, Jesper / Othman, Marwan H / Stavngaard, Trine / Kondziella, Daniel

PeerJ

2023 Volume 11, Page(s) e15759

Abstract: Background: Demand for organs exceeds the number of transplants available, underscoring the need to optimize organ donation procedures. However, protocols for determining brain death (BD)/death by neurological criteria (DNC) vary considerably worldwide. ...

Abstract	Background: Demand for organs exceeds the number of transplants available, underscoring the need to optimize organ donation procedures. However, protocols for determining brain death (BD)/death by neurological criteria (DNC) vary considerably worldwide. In Denmark, digital subtraction angiography (DSA) is the only legally approved confirmatory test for diagnosing BD/DNC. We investigated the effect of the time delay caused by (repeat) confirmatory DSA on the number of organs donated by patients meeting clinical criteria for BD/DNC. We hypothesized that, first, patients investigated with ≥2 DSAs donate fewer organs than those investigated with a single DSA; second, radiological interpretation of DSA is subject to interrater variability; and third, residual intracranial circulation is inversely correlated with inotropic blood pressure support. Methods: All DSAs performed over a 7-year period as part of BD/DNC protocols at Rigshospitalet, Copenhagen University Hospital, Denmark, were included. Clinical data were extracted from electronic health records. DSAs were reinterpreted by an independent neurinterventionist blinded to the original radiological reports. Results: We identified 130 DSAs in 100 eligible patients. Patients with ≥2 DSAs ( Discussion: In potential donors who fulfill clinical BD/DNC criteria, delays caused by repetition of confirmatory DSA result in lost donors and organ transplants. Self-maintained blood pressure at the time of clinical BD/DNC increases the odds for residual intracranial circulation, creating diagnostic uncertainty because radiological DSA interpretation is not uniform. We suggest that avoiding unnecessary repetition of confirmatory investigations like DSA may result in more organs donated.
MeSH term(s)	Humans ; Brain Death/diagnosis ; Angiography, Digital Subtraction/methods ; Tissue Donors ; Organ Transplantation ; Tissue and Organ Procurement
Language	English
Publishing date	2023-07-21
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.15759
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Article ; Online: Glycomacropeptide Impacts Amylin-Mediated Satiety, Postprandial Markers of Glucose Homeostasis, and the Fecal Microbiome in Obese Postmenopausal Women.

Hansen, Karen E / Murali, Sangita / Chaves, Ibrahim Z / Suen, Garret / Ney, Denise M

The Journal of nutrition

2023 Volume 153, Issue 7, Page(s) 1915–1929

Abstract: Background: Obesity with metabolic syndrome is highly prevalent and shortens lifespan.: Objectives: In a dose-finding crossover study, we evaluated the effect of glycomacropeptide (GMP) on satiety, glucose homeostasis, amino acid concentrations, ... ...

Abstract	Background: Obesity with metabolic syndrome is highly prevalent and shortens lifespan. Objectives: In a dose-finding crossover study, we evaluated the effect of glycomacropeptide (GMP) on satiety, glucose homeostasis, amino acid concentrations, inflammation, and the fecal microbiome in 13 obese women. Methods: Eligible women were ≤10 yr past menopause with a body mass index [BMI (in kg/m Results: The mean ± SE age of the 13 women was 57 ± 1 yr, with a median of 8 yr (range: 3-9 yr) past menopause and a BMI of 30 (IQR: 29-32). GMP was highly acceptable to participants, permitting high adherence. Metabolic effects were similar for twice or thrice daily GMP supplementation. Glucose, insulin, and cytokine concentrations were no different. The postprandial area under the curve (AUC) for glucagon concentrations was significantly lower, and the insulin-glucagon ratio was significantly higher with GMP than that with the soy MTT. Postprandial AUC amylin concentration was significantly higher with GMP than that with the soy MTT and correlated with C-peptide (P < 0.001; R Conclusions: GMP is shown to increase amylin concentrations, improve glucose homeostasis, and alter the fecal microbiome. GMP can be a helpful nutritional supplement in obese postmenopausal women at risk for metabolic syndrome. Further investigation is warranted. This trial was registered at clinicaltrials.gov as NCT05551091.
MeSH term(s)	Humans ; Female ; Islet Amyloid Polypeptide ; Glucagon ; Metabolic Syndrome ; Cross-Over Studies ; Postmenopause ; Obesity/metabolism ; Insulin ; Glucose ; Homeostasis ; Postprandial Period ; Blood Glucose/metabolism
Chemical Substances	caseinomacropeptide ; Islet Amyloid Polypeptide ; Glucagon (9007-92-5) ; Insulin ; Glucose (IY9XDZ35W2) ; Blood Glucose
Language	English
Publishing date	2023-04-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.1016/j.tjnut.2023.03.014
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Article ; Online: [Wellens syndrom].

Winsløw, Frederik / Hansen, Karen Marianne / Winsløw, Ulrik Christian

Ugeskrift for laeger

2020 Volume 182, Issue 43

MeSH term(s)	Chest Pain ; Coronary Angiography ; Electrocardiography ; Humans
Language	Danish
Publishing date	2020-10-28
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	124102-3
ISSN	1603-6824 ; 0041-5782
ISSN (online)	1603-6824
ISSN	0041-5782
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