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  1. Article: Xiang Qin Kang Gan Granules Treated the Human Coronavirus 229E Induced Pneumonia with Damp-Heat Syndrome in Mice.

    Cao, Fang / Liu, Zhaoheng / Hao, Qingxun / Zhao, Ronghua / Bao, Lei / Cui, Xiaolan / Jiao, Yang

    The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

    2022  Volume 2022, Page(s) 7609550

    Abstract: Coronavirus disease 2019 (COVID-19), which causes severe respiratory illness, was first reported in Wuhan, China. The etiology of the disease is a new novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was ... ...

    Abstract Coronavirus disease 2019 (COVID-19), which causes severe respiratory illness, was first reported in Wuhan, China. The etiology of the disease is a new novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was reported to share the same origin as SARS-CoV, causing severe public health events in 2002. Unlike the SARS-CoV, which was conquered in the early summer of 2003, this virus was still contagious widely and reached a pandemic level. It can still spread fast even if the season's temperature is raised. Here, we made a model of pneumonia of human coronavirus 229E (HCoV-229E) with damp-heat syndrome treated by Xiangqin Kanggan granules to find a new medicine for treating these kinds of infectious diseases coronaviruses induced.
    Language English
    Publishing date 2022-09-23
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 1057056-1
    ISSN 1712-9532 ; 1180-2332
    ISSN 1712-9532 ; 1180-2332
    DOI 10.1155/2022/7609550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Acute exacerbation of idiopathic pulmonary fibrosis treated using the Feibi recipe: Two case reports.

    Liu, Zhao-Heng / Li, Guo-Dong / Hao, Qing-Xun / Cao, Fang / Cheng, Yu / Kou, Meng-Jia / Jiao, Yang

    World journal of clinical cases

    2023  Volume 11, Issue 24, Page(s) 5742–5748

    Abstract: Background: Rationale: No other treatment besides lung transplant is effective for idiopathic pulmonary fibrosis (IPF). Patients with IPF have poor prognosis, which may eventually lead to death. Patient concerns: Two female patients were diagnosed with ... ...

    Abstract Background: Rationale: No other treatment besides lung transplant is effective for idiopathic pulmonary fibrosis (IPF). Patients with IPF have poor prognosis, which may eventually lead to death. Patient concerns: Two female patients were diagnosed with IPF. In our recent follow-up, both these patients maintained a good quality of life.
    Case summary: Diagnosis: Both patients had dry cough and progressive dyspnea. Interventions: The first patient was treated with prednisone, and the second patient was treated with prednisone and tripterygium glycosides. However, the symptoms did not improve and fibrosis was not controlled. Thus, the Feibi recipe was used. Outcomes: No deterioration was observed after the treatment, and the dry cough and its effect were ameliorated. Furthermore, they are still alive and the quality of their lives has improved.
    Conclusion: These two cases suggest that the Feibi recipe and other traditional Chinese medicine therapies could be beneficial for IPF treatment.
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i24.5742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Astragaloside IV Synergizing with Ferulic Acid Ameliorates Pulmonary Fibrosis by TGF-

    Tong, Jiahuan / Wu, Zhisong / Wang, Yuchen / Hao, Qingxun / Liu, Haoge / Cao, Fang / Jiao, Yang

    Evidence-based complementary and alternative medicine : eCAM

    2021  Volume 2021, Page(s) 8845798

    Abstract: Objective: The study aims to research the interventional effect and mechanism of astragaloside IV (Ast) synergizing with ferulic acid (FA) on idiopathic pulmonary fibrosis (IPF) induced by bleomycin in mice.: Methods: The mice were randomly divided ... ...

    Abstract Objective: The study aims to research the interventional effect and mechanism of astragaloside IV (Ast) synergizing with ferulic acid (FA) on idiopathic pulmonary fibrosis (IPF) induced by bleomycin in mice.
    Methods: The mice were randomly divided into seven groups with 10 mice in each group, namely, a sham operation group, a model group, a miRNA-29b (miR-29) group, a miR-29b negative control group (NC group), a FA group, an Ast group, and a combination group. A mouse model of pulmonary fibrosis was established by intratracheal instillation of bleomycin. Samples were collected after 28 days of continuous administration. Hematoxylin and eosin (HE) and Masson staining were used to observe pathological changes in the lung tissue, and the degree of fibrosis was evaluated using the hydroxyproline content. Changes in transforming growth factor-
    Results: Ferulic acid combined with astragaloside IV reduced the degree of pulmonary fibrosis and the synthesis of hydroxyproline in lung tissue. The combination of the two also regulated the oxidative stress response , TGF-
    Conclusion: Astragaloside IV combined with ferulic acid regulated the oxidative stress of lung tissues and TGF-
    Language English
    Publishing date 2021-03-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2021/8845798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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