LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 34

Search options

  1. Article: Structural Study of the Thermoelectric Work Units Encapsulated with Cement Paste for Building Energy Harvesting.

    Lai, Ziqiang / Hao, Yali / Wei, Yongqi / She, Anming / Yao, Wu

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 4

    Abstract: Cement-based material encapsulation is a method of encapsulating electronic devices in highly thermally conductive cement-based materials to improve the heat dissipation performance of electronic components. In the field of construction, a thermoelectric ...

    Abstract Cement-based material encapsulation is a method of encapsulating electronic devices in highly thermally conductive cement-based materials to improve the heat dissipation performance of electronic components. In the field of construction, a thermoelectric generator (TEG) encapsulated with cement-based materials used in the building envelope has significant potential for waste heat energy recovery. The purpose of this study was to investigate the effect of cement-based materials integrated with aluminum heatsinks on the heat dissipation of the TEG composite structure. In this work, three types of thermoelectric work units encapsulated with cement paste were proposed. Moreover, we explored the effect of encapsulated structure, heat dissipation area, the height of thermoelectric single leg, and heat input temperature on maintaining the temperature difference between the two sides of the thermoelectric single leg with COMSOL Multiphysics. The numerical simulation results showed that under the conditions of a heat source temperature of 313.15 K and ambient temperature of 298.15 K, the temperature difference between the two sides of the internal thermoelectric single leg of Type-III can maintain a stable temperature difference of 7.77 K, which is 32.14% higher than that of Type-I and Type-II (5.88 K), and increased by 26.82% in the actual experiment. This work provides a reference for the selection and application of TEG composite structures of cement-based materials combined with aluminum heatsinks.
    Language English
    Publishing date 2024-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17040926
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Fondaparinux Results in Similar Pregnancy Outcomes with Lower Adverse Reaction Rates Compared to Low Molecular Weight Heparin in Chinese Recurrent Miscarriage Women.

    Liu, Chunmiao / Ma, Cui / Hao, Yali

    The Tohoku journal of experimental medicine

    2023  Volume 262, Issue 2, Page(s) 125–131

    Abstract: Fondaparinux inhibits thrombin generation by inactivating factor Xa, which has the potential to treat recurrent miscarriage (RM). However, more clinical evidence is required to support its application in Chinese women with RM. This research aimed to ... ...

    Abstract Fondaparinux inhibits thrombin generation by inactivating factor Xa, which has the potential to treat recurrent miscarriage (RM). However, more clinical evidence is required to support its application in Chinese women with RM. This research aimed to compare the live birth rate, gestational weeks at delivery, birth weight, Apgar score of newborns, and adverse reaction rates between fondaparinux and low molecular weight heparin (LMWH) in Chinese women with RM. Totally, 132 women with RM treated with fondaparinux or LMWH were included in this retrospective study. According to the corresponding treatment, women with RM were divided into the fondaparinux cohort (N = 45) and LMWH cohort (N = 87). The live birth rate was 68.9% in the fondaparinux cohort and 56.3% in the LMWH cohort, which was not different between the two cohorts (P = 0.161). Multivariable logistics regression analysis suggested that only previous miscarriage times (≥ 4 times vs. < 4 times) were independently related to a lower possibility of live birth in women with RM (odds ratio = 0.431, P = 0.036). It was also observed that gestational weeks at delivery (38.1 ± 1.4 vs. 37.7 ± 1.7 weeks) (P = 0.258), birth weight (2,923.7 ± 355.0 vs. 2,807.8 ± 334.0 g) (P = 0.144), and Apgar score of newborns (9.8 ± 0.5 vs. 9.6 ± 0.8) (P = 0.175) were not different between the fondaparinux cohort and LMWH cohort. Inspiringly, the total adverse reaction rate was reduced in the fondaparinux cohort vs. the LMWH cohort (20.0% vs. 37.9%) (P = 0.036). Fondaparinux results in similar pregnancy outcomes with lower adverse reaction rates compared to LMWH in Chinese women with RM.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Heparin, Low-Molecular-Weight/adverse effects ; Pregnancy Outcome ; Fondaparinux/adverse effects ; Anticoagulants/adverse effects ; Retrospective Studies ; Birth Weight ; Abortion, Habitual/drug therapy ; Abortion, Habitual/chemically induced ; China/epidemiology
    Chemical Substances Heparin, Low-Molecular-Weight ; Fondaparinux (J177FOW5JL) ; Anticoagulants
    Language English
    Publishing date 2023-12-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 123477-8
    ISSN 1349-3329 ; 0040-8727
    ISSN (online) 1349-3329
    ISSN 0040-8727
    DOI 10.1620/tjem.2023.J098
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Hypomethylation of the ENPP3 promoter region contributes to the occurrence and development of ovarian endometriosis via the AKT/mTOR/4EBP1 signaling pathway.

    Qin, Yuzhen / Li, Yishuai / Hao, Yali / Li, Yan / Kang, Shan

    Biomolecules & biomedicine

    2023  

    Abstract: Growing evidence indicates that aberrant methylation is pivotal in the development and progression of endometriosis (EMs). This study explores the relationship between abnormal methylation of the ENPP3 promoter and the pathogenesis of ovarian EMs, ... ...

    Abstract Growing evidence indicates that aberrant methylation is pivotal in the development and progression of endometriosis (EMs). This study explores the relationship between abnormal methylation of the ENPP3 promoter and the pathogenesis of ovarian EMs, focusing on its regulatory effect on ENPP3 expression. We analyzed the methylation levels of ENPP3 in ectopic endometrial tissues from ovarian EMs patients and in normal endometrial tissues from women without EMs. The expression and distribution of ENPP3 were evaluated using RT-qPCR and immunohistochemistry. Transwell assays were conducted to examine the impact of ENPP3 overexpression on the migratory and invasive capabilities of endometrial stromal cells. Our results demonstrated significantly reduced methylation levels at the CpG sites of the ENPP3 promoter region in ectopic endometrial tissues compared to normal endometrial tissues. RT-qPCR findings revealed a marked increase in ENPP3 expression in ovarian EMs tissues relative to endometrial tissues from patients without EMs, and this upregulation was negatively correlated with the methylation levels of the ENPP3 promoter region. Immunohistochemical analyses confirmed elevated ENPP3 expression in the glandular epithelial cells and stroma of ovarian EMs tissues. Furthermore, in vitro experiments showed that overexpressed ENPP3 notably intensified the invasion and migration of endometrial stromal cells. Transcriptome sequencing and functional analyses indicated that the increased ENPP3 expression activated the AKT/mTOR/4EBP1 signaling pathway. In summary, the study suggests that hypomethylation in the ENPP3 promoter region may contribute to the initiation and advancement of ovarian EMs by activating the AKT/mTOR/4EBP1 pathway, supporting the theory that EMs might be an epigenetically regulated disorder.
    Language English
    Publishing date 2023-12-27
    Publishing country Bosnia and Herzegovina
    Document type Journal Article
    ISSN 2831-090X
    ISSN (online) 2831-090X
    DOI 10.17305/bb.2023.9989
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Genome-wide transcriptome profiling reveals molecular response pathways of

    Yang, Qihong / Mao, Zhenchuan / Hao, Yali / Zheng, Shijie / Zhao, Jianlong / Li, Yan / Yang, Yuhong / Xie, Bingyan / Ling, Jian / Li, Yanlin

    Frontiers in microbiology

    2024  Volume 15, Page(s) 1342584

    Abstract: Trichoderma ... ...

    Abstract Trichoderma harzianum
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1342584
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Bilirubin ameliorates murine atherosclerosis through inhibiting cholesterol synthesis and reshaping the immune system.

    Wen, Guanmei / Yao, Leyi / Hao, Yali / Wang, Jinheng / Liu, Jinbao

    Journal of translational medicine

    2022  Volume 20, Issue 1, Page(s) 1

    Abstract: Atherosclerosis is a chronic inflammatory disease caused mainly by lipid accumulation and excessive inflammatory immune response. Although the lipid-lowering and cardioprotective properties of bilirubin, as well as the negative relationship between ... ...

    Abstract Atherosclerosis is a chronic inflammatory disease caused mainly by lipid accumulation and excessive inflammatory immune response. Although the lipid-lowering and cardioprotective properties of bilirubin, as well as the negative relationship between bilirubin and atherosclerosis, were well documented, it is not yet clear whether bilirubin can attenuate atherosclerosis in vivo. In this study, we investigated the role of bilirubin in improving atherosclerosis. We found that mildly elevated bilirubin significantly reduced the risk factors of atherosclerosis, such as plasma glucose, total cholesterol, and low-density lipoprotein cholesterol, and the formation of atherosclerotic plaques, liver total cholesterol, and cholesterol ester concentration in apolipoprotein E-deficient (ApoE
    MeSH term(s) Animals ; Apolipoproteins E ; Atherosclerosis ; Bilirubin ; Cholesterol, LDL ; Immune System/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Plaque, Atherosclerotic
    Chemical Substances Apolipoproteins E ; Cholesterol, LDL ; Bilirubin (RFM9X3LJ49)
    Language English
    Publishing date 2022-01-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2118570-0
    ISSN 1479-5876 ; 1479-5876
    ISSN (online) 1479-5876
    ISSN 1479-5876
    DOI 10.1186/s12967-021-03207-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Recent Advances in Properties and Applications of Carbon Fiber-Reinforced Smart Cement-Based Composites.

    Hao, Yali / Shi, Cheng / Bi, Zhenxiao / Lai, Ziqiang / She, Anming / Yao, Wu

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 7

    Abstract: Under the strategies of low-carbon and environmental protection, promoting green technology innovation to achieve carbon neutrality in the construction field has become a universal goal. As the building material with the highest consumption, concrete has ...

    Abstract Under the strategies of low-carbon and environmental protection, promoting green technology innovation to achieve carbon neutrality in the construction field has become a universal goal. As the building material with the highest consumption, concrete has gradually begun to transform into a multi-functional and intelligent product. Therefore, the research on carbon fiber-reinforced cement-based composites (CFRCs) is of relative interest. It mainly uses carbon fibers (CFs) with high elasticity, strength, and conductivity to disperse evenly into the concrete as a functional filler, to achieve the intelligent integration of concrete structures and function innovatively. Furthermore, the electrical conductivity of CFRC is not only related to the content of CFs and environmental factors but also largely depends on the uniform dispersion and the interfacial bonding strength of CFs in cement paste. This work systematically presents a review of the current research status of the enhancement and modification mechanism of CFRC and the evaluation methods of CF dispersion. Moreover, it further discusses the improvement effects of different strengthening mechanisms on the mechanical properties, durability, and smart properties (thermoelectric effect, electrothermal effect, strain-sensitive effect) of CFRC, as well as the application feasibility of CFRC in structural real-time health monitoring, thermal energy harvesting, intelligent deformation adjustment, and other fields. Furthermore, this paper summarizes the problems and challenges faced in the efficient and large-scale applications of CFRCs in civil engineering structures, and accordingly promotes some proposals for future research.
    Language English
    Publishing date 2023-03-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16072552
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Effect of tumor-stromal fibroblasts on the biological behavior of salivary gland pleomorphic adenoma cells

    Hou, Yali / Li, Hexiang / Song, Peng / Yang, Yanxiao / Hao, Yali / Liu, Huijuan

    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

    2023  Volume 41, Issue 2, Page(s) 149–156

    Abstract: Objectives: This study aims to investigate the effects of tumor-stromal fibroblasts (TSFs) on the proliferation, invasion, and migration of salivary gland pleomorphic adenoma (SPA) cells : Methods: Salivary gland pleomorphic adenoma cells (SPACs), ... ...

    Abstract Objectives: This study aims to investigate the effects of tumor-stromal fibroblasts (TSFs) on the proliferation, invasion, and migration of salivary gland pleomorphic adenoma (SPA) cells
    Methods: Salivary gland pleomorphic adenoma cells (SPACs), TSFs, and peri-tumorous normal fibroblasts (NFs) were obtained by tissue primary culture and identified by immunocytochemical staining. The conditioned medium was obtained from TSF and NF in logarithmic phase. SPACs were cultured by conditioned medium and treated by TSF (group TSF-SPAC) and NF (group NF-SPAC). SPACs were used as the control group. The proliferation, invasion, and migration of the three groups of cells were detected by MTT, transwell, and scratch assays, respectively. The expression of vascular endothelial growth factor (VEGF) in the three groups was tested by enzyme linked immunosorbent assay (ELISA).
    Results: Immunocytochemical staining showed positive vimentin expression in NF and TSF. Results also indicated the weak positive expression of α-smooth muscle actin (SMA) and fibroblast activation protein (FAP) in TSFs and the negative expression of α-SMA and FAP in NFs. MTT assay showed that cell proliferation in the TSF-SPAC group was significantly different from that in the NF-SPAC and SPAC groups (
    Conclusions: TSFs may be involved in SPA biological behavior by promoting the proliferation of SPACs but has no effect on the invasion and migration of SPACs
    MeSH term(s) Humans ; Adenoma, Pleomorphic/metabolism ; Vascular Endothelial Growth Factor A ; Culture Media, Conditioned/metabolism ; Fibroblasts/metabolism ; Salivary Glands/metabolism
    Chemical Substances Vascular Endothelial Growth Factor A ; Culture Media, Conditioned
    Language Chinese
    Publishing date 2023-04-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 1202342-5
    ISSN 2618-0456 ; 1000-1182
    ISSN (online) 2618-0456
    ISSN 1000-1182
    DOI 10.7518/hxkq.2023.2022314
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Resveratrol improves ovarian function in aged rat by inhibiting oxidative stress and activating the Sirt1.

    Wu, Haifeng / Xue, Jianchang / Di, Hongqin / Lv, Cuiting / Hao, Yali / Nie, Zhaoyan

    General physiology and biophysics

    2022  Volume 41, Issue 1, Page(s) 53–61

    Abstract: Oxidative stress is a leading driver of ovarian aging. Silent mating-type information regulation 2 homolog-1 (Sirt1) plays an role in ovarian function. Resveratrol has numerous effects, including anti-oxidant and Sirt1 activator. The aim of the study was ...

    Abstract Oxidative stress is a leading driver of ovarian aging. Silent mating-type information regulation 2 homolog-1 (Sirt1) plays an role in ovarian function. Resveratrol has numerous effects, including anti-oxidant and Sirt1 activator. The aim of the study was to investigate the effect of resveratrol on aging-induced ovarian change in rats. The female Sprague Dawley rats were randomly divided into three groups: young control (Con), Aged+Res (20 mg/kg/day resveratrol for 45 days), and Aged. Anti-Müllerian hormone (AMH) was detected by ELISA assay. Malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were detected by conventional method. The ovarian structure and follicles were observed by hematoxylin staining, the caspase-3 and Sirt1 were detected by immunohistochemistry and Western blotting. The AMH in the Aged+Res group was elevated, compared to that in Aged group (p < 0.05). The MDA was decreased and GSH-Px and SOD were increased in the Aged+Res group (p < 0.05). The primordial and primary follicles were increased in the Aged+Res group (p < 0.05). The Sirt1 was increased and caspase-3 was decreased in the Aged+Res group (p < 0.05). These results indicate that resveratrol can delay ovarian aging, probably by reducing oxidative damage and increasing Sirt1.
    MeSH term(s) Animals ; Antioxidants/pharmacology ; Female ; Ovary/drug effects ; Oxidative Stress/drug effects ; Rats ; Rats, Sprague-Dawley ; Resveratrol/pharmacology ; Sirtuin 1/metabolism ; Sirtuin 1/pharmacology
    Chemical Substances Antioxidants ; Sirt1 protein, rat (EC 3.5.1.-) ; Sirtuin 1 (EC 3.5.1.-) ; Resveratrol (Q369O8926L)
    Language English
    Publishing date 2022-03-06
    Publishing country Slovakia
    Document type Journal Article
    ZDB-ID 791184-1
    ISSN 0231-5882
    ISSN 0231-5882
    DOI 10.4149/gpb_2021040
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Induction of Heme Oxygenase-1 Modifies the Systemic Immunity and Reduces Atherosclerotic Lesion Development in ApoE Deficient Mice.

    Yao, Leyi / Hao, Yali / Wen, Guanmei / Xiao, Qingzhong / Wu, Penglong / Wang, Jinheng / Liu, Jinbao

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 809469

    Abstract: Heme oxygenase-1 (HO-1) has been reported to protect against oxidation and inflammation in atherosclerosis. It remains unclear how the immune system participates in the cytoprotective function of HO-1 in the context of atherosclerosis. In this study, we ... ...

    Abstract Heme oxygenase-1 (HO-1) has been reported to protect against oxidation and inflammation in atherosclerosis. It remains unclear how the immune system participates in the cytoprotective function of HO-1 in the context of atherosclerosis. In this study, we attempted to investigate the potential effect of a HO-1 inducer, hemin, and a HO-1 inhibitor, Tin-protoporphyrin IX (SnPP), on the progression of atherosclerosis in ApoE deficient mice. Using mass cytometry, 15 immune cell populations and 29 T cell sub-clusters in spleen and peripheral blood were thoroughly analyzed after hemin or SnPP treatment. SnPP elevated risk factors of atherosclerosis, whereas hemin reduced them. In-depth analysis showed that hemin significantly modified the immune system in both spleen and peripheral blood. Hemin increased dendritic (DC) and myeloid-derived suppressor cells (MDSCs), but decreased natural killer (NK) cells. An opposite effect was observed with SnPP treatment in terms of NK cells. NK cells and MDSCs were positively and negatively correlated with total cholesterol and low-density lipoprotein, respectively. Moreover, the T cell profiles were significantly reshaped by hemin, whereas only minor changes were observed with SnPP. Several hemin-modulated T cell clusters associated with atherosclerosis were also identified. In summary, we have unraveled an important regulatory role for HO-1 pathway in immune cell regulation and atherosclerosis. Our finding suggests that modulating HO-1 signaling represents a potential therapeutic strategy against atherosclerosis.
    Language English
    Publishing date 2022-02-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.809469
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: The Genome of

    Hao, Yali / Li, Yan / Ping, Xingxing / Yang, Qihong / Mao, Zhenchuan / Zhao, Jianlong / Lu, Xiaofei / Xie, Bingyan / Yang, Yuhong / Ling, Jian

    International journal of molecular sciences

    2023  Volume 24, Issue 2

    Abstract: ... Fusarium ... ...

    Abstract Fusarium oxysporum
    MeSH term(s) Fusarium/genetics ; Plant Diseases ; Genome, Fungal
    Language English
    Publishing date 2023-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24020963
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top