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  1. Article: Effects of gut bacteria and their metabolites on gut health of animals.

    Hao, Zhuang / Ding, Xuedong / Wang, Jing

    Advances in applied microbiology

    2024  Volume 127, Page(s) 223–252

    Abstract: The intestine tract is a vital site for the body to acquire nutrients, serving as the largest immune organ. Intestinal health is crucial for maintaining a normal physiological state. Abundant microorganisms reside in the intestine, colonized in a ... ...

    Abstract The intestine tract is a vital site for the body to acquire nutrients, serving as the largest immune organ. Intestinal health is crucial for maintaining a normal physiological state. Abundant microorganisms reside in the intestine, colonized in a symbiotic manner. These microorganisms can generate various metabolites that influence host physiological activities. Microbial metabolites serve as signaling molecules or metabolic substrates in the intestine, and some intestinal microorganisms act as probiotics and promote intestinal health. Researches on host, probiotics, microbial metabolites and their interactions are ongoing. This study reviews the effects of gut bacteria and their metabolites on intestinal health to provide useful references for animal husbandry.
    MeSH term(s) Animals ; Gastrointestinal Microbiome ; Probiotics/metabolism ; Bacteria/metabolism ; Bacteria/genetics ; Intestines/microbiology
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 160-0
    ISSN 0065-2164
    ISSN 0065-2164
    DOI 10.1016/bs.aambs.2024.02.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The effects of parental retirement on adult children's health: Evidence from China.

    Hao, Zhuang / Cheng, Huihui / Bärnighausen, Till / Chen, Simiao

    Health economics

    2023  Volume 33, Issue 1, Page(s) 12–20

    Abstract: Using representative data from China, we examine the causal effects of parental retirement on the health of adult children. To do so, we adopt a fuzzy regression discontinuity design and exploit the mandatory retirement ages in China as cut-off points. ... ...

    Abstract Using representative data from China, we examine the causal effects of parental retirement on the health of adult children. To do so, we adopt a fuzzy regression discontinuity design and exploit the mandatory retirement ages in China as cut-off points. We find no evidence that parental retirement has significant effects on the mental health, healthcare utilization, or risky health behaviors of adult children. However, paternal retirement and maternal retirement have different effects on adult children's Self-reported health (SRH). Paternal retirement has a significantly negative effect only on the SRH of sons, while maternal retirement does not induce such effects. Potential mechanisms of intergenerational transfer through which parental retirement might affect adult children's health are also explored.
    MeSH term(s) Adult ; Child ; Humans ; Retirement/psychology ; Child Health ; Parents/psychology ; Mental Health ; China/epidemiology
    Language English
    Publishing date 2023-10-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1135838-5
    ISSN 1099-1050 ; 1057-9230
    ISSN (online) 1099-1050
    ISSN 1057-9230
    DOI 10.1002/hec.4767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Medicaid expansion and the mental health of college students.

    Cowan, Benjamin W / Hao, Zhuang

    Health economics

    2021  Volume 30, Issue 6, Page(s) 1306–1327

    Abstract: Reported mental health problems have risen dramatically among US college students over time, as has treatment for these problems. We examine the effect of state-level Medicaid expansion following the 2014 implementation of the Affordable Care Act on the ... ...

    Abstract Reported mental health problems have risen dramatically among US college students over time, as has treatment for these problems. We examine the effect of state-level Medicaid expansion following the 2014 implementation of the Affordable Care Act on the diagnosis of mental health conditions, psychotropic prescription drug use, and the mental health status of a national sample of college students. We find that students from disadvantaged backgrounds are more likely to report being on public insurance after 2014 in expansion states relative to non-expansion states, while more advantaged students do not see this increase. Both diagnosis of common mental health conditions and psychotropic drug use increase following expansion for disadvantaged students relative to advantaged ones, which translates into an elimination of the pre-expansion gap in these outcomes by family background in expansion states. However, in contrast to some recent work on Medicaid expansion and mental health, we do not find that these changes are associated with improvements in self-reported mental health status. We also do not find that Medicaid expansion has affected risky health behaviors or academic outcomes.
    MeSH term(s) Health Services Accessibility ; Humans ; Insurance Coverage ; Medicaid ; Mental Health ; Patient Protection and Affordable Care Act ; Students ; United States
    Language English
    Publishing date 2021-03-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1135838-5
    ISSN 1099-1050 ; 1057-9230
    ISSN (online) 1099-1050
    ISSN 1057-9230
    DOI 10.1002/hec.4256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3555: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: [Gene Profile and Clinical Significance of Concomitant Mutations in CN-AML Patients with

    Zhu, Jing / Kang, Ye-Fang / Gao, Yuan / Wang, Hong-Wei / Hao, Zhuang-Hui

    Zhongguo shi yan xue ye xue za zhi

    2024  Volume 32, Issue 2, Page(s) 335–341

    Abstract: Objective: To analyze the occurrence of concomitant gene mutations in cytogenetically normal acute myeloid leukemia (CN-AML) patients with : Methods: 151 newly diagnosed patients with CN-AML in the Second Hospital of Shanxi Medical University from ... ...

    Abstract Objective: To analyze the occurrence of concomitant gene mutations in cytogenetically normal acute myeloid leukemia (CN-AML) patients with
    Methods: 151 newly diagnosed patients with CN-AML in the Second Hospital of Shanxi Medical University from June 2013 to June 2020 were analyzed retrospectively. 34 common genetic mutations associated with hematologic malignancies were detected by next-generation sequencing technology. The occurrence of concomitant gene mutations in patients with
    Results: In 151 patients with CN-AML, 55 (36.42%) were positive for
    Conclusion: CN-AML patients with
    MeSH term(s) Humans ; Leukemia, Myeloid, Acute/genetics ; Mutation ; CCAAT-Enhancer-Binding Proteins/genetics ; Retrospective Studies ; Prognosis ; Dioxygenases ; GATA2 Transcription Factor/genetics ; DNA-Binding Proteins/genetics ; Proto-Oncogene Proteins/genetics ; WT1 Proteins/genetics ; Male ; Female ; Clinical Relevance
    Chemical Substances CCAAT-Enhancer-Binding Proteins ; CEBPA protein, human ; TET2 protein, human (EC 1.13.11.-) ; Dioxygenases (EC 1.13.11.-) ; GATA2 Transcription Factor ; GATA2 protein, human ; DNA-Binding Proteins ; Proto-Oncogene Proteins ; WT1 Proteins ; WT1 protein, human
    Language Chinese
    Publishing date 2024-04-25
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2404306-0
    ISSN 1009-2137
    ISSN 1009-2137
    DOI 10.19746/j.cnki.issn.1009-2137.2024.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Monitoring Cd

    Wang, Hao / Hao, Zhuang / Huang, Cong / Li, Feiran / Pan, Yunlu

    Nanoscale advances

    2022  Volume 5, Issue 5, Page(s) 1416–1424

    Abstract: The discharge of oily industrial wastewater containing heavy metal ions with the development of industry severely threatens the environment and human health. Therefore, it is of great significance to monitor the concentration of heavy metal ions in oily ... ...

    Abstract The discharge of oily industrial wastewater containing heavy metal ions with the development of industry severely threatens the environment and human health. Therefore, it is of great significance to monitor the concentration of heavy metal ions in oily wastewater quickly and effectively. Here, an integrated Cd
    Language English
    Publishing date 2022-12-13
    Publishing country England
    Document type Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d2na00416j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: The effects of graduation requirements on risky health behaviors of high school students

    Hao, Zhuang / Cowan, Benjamin

    (Working paper series / National Bureau of Economic Research ; 23803)

    2017  

    Author's details Zhuang Hao, Benjamin W. Cowan
    Series title Working paper series / National Bureau of Economic Research ; 23803
    Language English
    Size 58 Seiten, Illustrationen
    Publisher National Bureau of Economic Research
    Publishing place Cambridge, MA
    Document type Book
    Note Erscheint auch als Online-Ausgabe
    Database ECONomics Information System

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  7. Book: The cross-border spillover effects of recreational marijuana legalization

    Hao, Zhuang / Cowan, Benjamin

    (Working paper series / National Bureau of Economic Research ; 23426)

    2017  

    Author's details Zhuang Hao, Benjamin Cowan
    Series title Working paper series / National Bureau of Economic Research ; 23426
    Keywords Cannabis ; Drogenkonsum ; Legalisierung ; Teilstaat ; Spillover-Effekt ; Strafvollzug ; Colorado (Staat) ; Washington (Staat) ; USA
    Language English
    Size 50 Seiten, Illustrationen
    Publisher National Bureau of Economic Research
    Publishing place Cambridge, MA
    Document type Book
    Note Erscheint auch als Online-Ausgabe
    Database ECONomics Information System

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    Inter-library loan at ZB MED

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  8. Article: Birds and plastic pollution: recent advances.

    Wang, Limin / Nabi, Ghulam / Yin, Liyun / Wang, Yanqin / Li, Shuxin / Hao, Zhuang / Li, Dongming

    Avian research

    2021  Volume 12, Issue 1, Page(s) 59

    Abstract: Plastic waste and debris have caused substantial environmental pollution globally in the past decades, and they have been accumulated in hundreds of terrestrial and aquatic avian species. Birds are susceptible and vulnerable to external environments; ... ...

    Abstract Plastic waste and debris have caused substantial environmental pollution globally in the past decades, and they have been accumulated in hundreds of terrestrial and aquatic avian species. Birds are susceptible and vulnerable to external environments; therefore, they could be used to estimate the negative effects of environmental pollution. In this review, we summarize the effects of macroplastics, microplastics, and plastic-derived additives and plastic-absorbed chemicals on birds. First, macroplastics and microplastics accumulate in different tissues of various aquatic and terrestrial birds, suggesting that birds could suffer from the macroplastics and microplastics-associated contaminants in the aquatic and terrestrial environments. Second, the detrimental effects of macroplastics and microplastics, and their derived additives and absorbed chemicals on the individual survival, growth and development, reproductive output, and physiology, are summarized in different birds, as well as the known toxicological mechanisms of plastics in laboratory model mammals. Finally, we identify that human commensal birds, long-life-span birds, and model bird species could be utilized to different research objectives to evaluate plastic pollution burden and toxicological effects of chronic plastic exposure.
    Language English
    Publishing date 2021-11-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2806572-4
    ISSN 2053-7166
    ISSN 2053-7166
    DOI 10.1186/s40657-021-00293-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effects of Chinese wolfberry and Astragalus extract on the antioxidant capacity of Tibetan pig liver.

    Hao, Zhuang / Li, Zhen / Huo, Jinjin / Li, Jiandong / Liu, Fenghua / Yin, Peng

    PloS one

    2021  Volume 16, Issue 1, Page(s) e0245749

    Abstract: The objective of this study is to determine the effect of Chinese wolfberry (Lycium barbarum) and Astragalus (Astragalus membranaceus) extract (WAE) on the antioxidant capacity of Tibetan pig liver, and discussed the regulatory effect of WAE on the liver ...

    Abstract The objective of this study is to determine the effect of Chinese wolfberry (Lycium barbarum) and Astragalus (Astragalus membranaceus) extract (WAE) on the antioxidant capacity of Tibetan pig liver, and discussed the regulatory effect of WAE on the liver antioxidant mechanism. Twelve healthy 120-day-old Tibetan black pigs (35±2 kg) were divided randomly into two groups. The WAE group was fed a basal diet supplemented with 1% WAE for 90 days. The control group was fed the same diet, but without the WAE. We found that liver superoxide dismutase 1 (SOD1) activity (P<0.05), total antioxidative capacity (T-AOC) (P<0.05), and catalase (CAT) activity (P<0.01) significantly increased in the WAE group compared with the control group; malondialdehyde (MDA) content decreased, but this was not significant (P >0.05). Transcriptome sequencing analysis detected 106 differentially expressed genes (DEGs) related to oxidative stress. GO enrichment analysis showed these DEGs were involved in the positive regulation of reactive oxygen metabolism and biosynthesis, process regulation, and regulation of the oxidative stress response. KEGG Pathway enrichment analysis showed they were enriched in the PI3K-Akt, AMPK, Rap1, and peroxisome signaling pathways. The expression levels of key peroxisome biosynthesis genes (e.g., PEX3 and PEX11B) and key antioxidant genes (e.g., CAT and SOD1) were significantly higher in the WAE group than in the control group. The PRDX1 and PRDX5 content also was significantly higher in the WAE group. This study showed that the WAE regulated the antioxidant and anti-stress ability of Tibetan pig liver through a "peroxisome antioxidant-oxidant stress" signaling pathway.
    MeSH term(s) Animals ; Antioxidants/pharmacology ; Astragalus Plant/chemistry ; Liver/drug effects ; Liver/metabolism ; Lycium/chemistry ; Peroxins/genetics ; Peroxins/metabolism ; Peroxisomes/metabolism ; Plant Extracts/pharmacology ; Signal Transduction ; Swine
    Chemical Substances Antioxidants ; Peroxins ; Plant Extracts
    Language English
    Publishing date 2021-01-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0245749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effects of Chinese wolfberry and astragalus extracts on growth performance, pork quality, and unsaturated fatty acid metabolism regulation in Tibetan fragrant pigs

    Hao, Zhuang / Li, Zhen / Huo, Jinjin / Chu, Yaocheng / Li, Jiandong / Yu, Xiaohong / Liu, Fenghua / Yin, Peng

    Animal science journal =. 2021 Dec., v. 92, no. 1

    2021  

    Abstract: We studied the effects of wolfberry and astragalus extract on the growth performance, carcass traits, and meat quality of Tibetan fragrant pigs, and we want to explain the mechanism of the difference from the level of RNA Seq. Twelve healthy 120‐day‐old ... ...

    Abstract We studied the effects of wolfberry and astragalus extract on the growth performance, carcass traits, and meat quality of Tibetan fragrant pigs, and we want to explain the mechanism of the difference from the level of RNA Seq. Twelve healthy 120‐day‐old Tibetan fragrant pigs weighing 35 ± 2 kg were divided randomly into two groups, each with six pigs. The control group was fed a basal diet, and the wolfberry and astragalus extract (WAE) group was fed a basal diet +1‰ of WAE. The experimental period was 90 days. Compared with the control group, the growth performance of the WAE group was significantly improved (p < .05), pork marble score significantly improved (p < .05), vitamin E content significantly increased (p < .05), unsaturated fatty acid content significantly increased (p < .05). A total of 256 differentially expressed genes were obtained by transcriptome sequencing, among which 114 were up‐regulated and 142 were down‐regulated. GO analysis showed that the differentially expressed genes were related to biological functions, such as monounsaturated fatty acid biosynthesis, fatty acid metabolism, lipoprotein decomposition, and lipase activity. Pathway analysis showed that these differentially expressed genes were mainly involved in unsaturated fatty acid biosynthesis regulation, glycerin metabolism, and lipopolysaccharide regulation in fat. WAE improved Tibetan fragrant pigs growth performance. By intervening in key genes related to fatty acid metabolism, the unsaturated fatty acid contents in pork were regulated, which improved the nutritional value of the pork.
    Keywords Lycium ; RNA ; biosynthesis ; carboxylic ester hydrolases ; diet ; fatty acid composition ; fatty acid metabolism ; gene expression regulation ; glycerol ; growth performance ; lipopolysaccharides ; lipoproteins ; monounsaturated fatty acids ; nutritive value ; pork ; pork quality ; transcriptome ; vitamin E
    Language English
    Dates of publication 2021-12
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2095161-9
    ISSN 1740-0929 ; 1344-3941
    ISSN (online) 1740-0929
    ISSN 1344-3941
    DOI 10.1111/asj.13581
    Database NAL-Catalogue (AGRICOLA)

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