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  1. Article ; Online: Higher risk of Achilles tendon ruptures at competition than training sites in female collegiate gymnasts.

    Muhlenhaupt, Emily / Stauss, Harald M

    The Journal of sports medicine and physical fitness

    2024  Volume 64, Issue 4, Page(s) 392–401

    Abstract: Background: Reportedly, 17.2% of collegiate female gymnasts experience Achilles tendon ruptures (ATRs). Cumulative microtraumas resulting in chronic tendinopathy/tendinitis may contribute to this high injury risk. We hypothesized that the risk of ATRs ... ...

    Abstract Background: Reportedly, 17.2% of collegiate female gymnasts experience Achilles tendon ruptures (ATRs). Cumulative microtraumas resulting in chronic tendinopathy/tendinitis may contribute to this high injury risk. We hypothesized that the risk of ATRs in female collegiate gymnasts increases with years of competitive gymnastics, that non-steroidal anti-inflammatory drug (NSAID) use is associated with less ATRs, and that the risk is larger during competition than training.
    Methods: Female gymnasts from 78 USA collegiate teams completed a survey assessing the prevalence of ATRs, NSAID use, age at which competitive gymnastics started and age at which ATR occurred, and whether ATRs occurred during training or competition.
    Results: Twenty-one of 103 gymnasts (20.4%, 95% CI: 13.6% to 29.4%) experienced ATRs. Eighteen of 21 ruptures (85.7%, 95% CI: 61.3% to 95.8%) occurred after more than ten years of competitive gymnastics (mean: 14.0±2.6 years, 95% CI: 12.8 to 15.2 years). ATRs occurred 0.08±0.01 (95% CI: 0.06 to 0.11) times per 1000 hours at training versus 1.85±0.11 (95% CI: 1.60 to 2.10) times per 1000 hours at competition (P<0.05). Prevalence of NSAID use was 27.6% (95% CI: 18.6% to 39.0%) in gymnasts without ATR but only 5.5% (95% CI: 0.6% to 35.5%, P=0.09) in gymnasts with ATR. Multiple regression analysis demonstrated a negative association between NSAID use and incidence of ATRs (P<0.05).
    Conclusions: Female collegiate gymnasts are at high risk for ATRs, especially after more than ten years of competitive gymnastics and during competition.
    MeSH term(s) Humans ; Female ; Achilles Tendon/injuries ; Gymnastics/injuries ; Tendon Injuries ; Universities ; Tendinopathy/epidemiology ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal
    Language English
    Publishing date 2024-01-09
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 410823-1
    ISSN 1827-1928 ; 0022-4707
    ISSN (online) 1827-1928
    ISSN 0022-4707
    DOI 10.23736/S0022-4707.23.15558-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A framework for the interpretation of heart rate variability applied to transcutaneous auricular vagus nerve stimulation and osteopathic manipulation.

    Kania, Adrienne / Roufail, Jumana / Prokop, Joseph / Stauss, Harald M

    Physiological reports

    2024  Volume 12, Issue 6, Page(s) e15981

    Abstract: Reports on autonomic responses to transcutaneous auricular vagus nerve stimulation (taVNS) and osteopathic manipulative techniques have been equivocal, partly due to inconsistent interpretation of heart rate variability (HRV). We developed a mechanistic ... ...

    Abstract Reports on autonomic responses to transcutaneous auricular vagus nerve stimulation (taVNS) and osteopathic manipulative techniques have been equivocal, partly due to inconsistent interpretation of heart rate variability (HRV). We developed a mechanistic framework for the interpretation of HRV based on a model of sinus node automaticity that considers autonomic effects on Phase 3 repolarization and Phase 4 depolarization of the sinoatrial action potential. The model was applied to HRV parameters calculated from ECG recordings (healthy adult humans, both genders) before (30 min), during (15 min), and after (30 min) a time control intervention (rest, n = 23), taVNS (10 Hz, 300 μs, 1-2 mA, cymba concha, left ear, n = 12), or occipitoatlantal decompression (OA-D, n = 14). The experimental protocol was repeated on 3 consecutive days. The model simulation revealed that low frequency (LF) HRV best predicts sympathetic tone when calculated from heart rate time series, while high frequency (HF) HRV best predicts parasympathetic tone when calculated from heart period time series. Applying our model to the HRV responses to taVNS and OA-D, revealed that taVNS increases cardiac parasympathetic tone, while OA-D elicits a mild decrease in cardiac sympathetic tone.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Heart Rate/physiology ; Vagus Nerve Stimulation/methods ; Manipulation, Osteopathic ; Vagus Nerve/physiology ; Autonomic Nervous System/physiology ; Transcutaneous Electric Nerve Stimulation/methods
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.15981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Conference proceedings: Beiträge zur Elefantenhaltung in Europa

    Winkler, Achim / Schwammer, Harald

    EEKMA-Tagung Duisburg, Februar 2004

    2005  

    Event/congress European Elephant Keeper and Manager Association
    Author's details EEKMA. Achim Winkler ; Harald M. Schwammer
    Keywords Europa ; Elefanten ; Zootierhaltung
    Subject Zootiere ; Elefant ; Elephantidae ; Elephants
    Language German
    Size 116 S. : Ill., graph. Darst.
    Publisher Schüling
    Publishing place Münster
    Publishing country Germany
    Document type Book ; Conference proceedings
    HBZ-ID HT014641261
    ISBN 3-86523-027-X ; 978-3-86523-027-0
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  4. Article ; Online: Differential hemodynamic and respiratory responses to right and left cervical vagal nerve stimulation in rats.

    Stauss, Harald M

    Physiological reports

    2017  Volume 5, Issue 7

    Abstract: Neuromodulation through vagal nerve stimulation (VNS) is currently explored for a variety of clinical conditions. However, there are no established VNS parameters for animal models of human diseases, such as hypertension. Therefore, the aim of this study ...

    Abstract Neuromodulation through vagal nerve stimulation (VNS) is currently explored for a variety of clinical conditions. However, there are no established VNS parameters for animal models of human diseases, such as hypertension. Therefore, the aim of this study was to assess hemodynamic and respiratory responses to right- or left-sided cervical VNS in a hypertensive rat model. Anesthetized stroke-prone spontaneously hypertensive rats were instrumented for arterial blood pressure and heart rate monitoring and left- or right-sided VNS Cervical VNS was applied through bipolar coil electrodes. Stimulation parameters tested were 3 V and 6 V, 2 Hz to 20 Hz stimulation frequency, and 50
    MeSH term(s) Animals ; Blood Pressure/physiology ; Functional Laterality/physiology ; Heart Rate/physiology ; Hemodynamics ; Hypertension/physiopathology ; Male ; Rats ; Rats, Inbred SHR ; Respiratory Rate/physiology ; Vagus Nerve/physiopathology ; Vagus Nerve Stimulation/methods
    Language English
    Publishing date 2017-04-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.13244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: DWI scrolling artery sign for the diagnosis of giant cell arteritis: a pattern recognition approach.

    Seitz, Luca / Bucher, Susana / Bütikofer, Lukas / Maurer, Britta / Bonel, Harald M / Lötscher, Fabian / Seitz, Pascal

    RMD open

    2024  Volume 10, Issue 1

    Abstract: Objectives: To investigate the diagnostic accuracy of a pattern recognition approach for the evaluation of MRI scans of the head with diffusion-weighted imaging (DWI) in suspected giant cell arteritis (GCA).: Methods: Retrospectively, 156 patients ... ...

    Abstract Objectives: To investigate the diagnostic accuracy of a pattern recognition approach for the evaluation of MRI scans of the head with diffusion-weighted imaging (DWI) in suspected giant cell arteritis (GCA).
    Methods: Retrospectively, 156 patients with suspected GCA were included. The 'DWI-Scrolling-Artery-Sign' (DSAS) was defined as hyperintense DWI signals in the cranial subcutaneous tissue that gives the impression of a blood vessel when scrolling through a stack of images. The DSAS was rated by experts and a novice in four regions (frontotemporal and occipital, bilaterally). The temporal, occipital and posterior auricular arteries were assessed in the T1-weighted black-blood sequence (T1-BB). The diagnostic reference was the clinical diagnosis after ≥6 months of follow-up.
    Results: The population consisted of 87 patients with and 69 without GCA; median age was 71 years and 59% were women. The DSAS showed a sensitivity of 73.6% and specificity of 94.2% (experts) and 59.8% and 95.7% (novice), respectively. Agreement between DSAS and T1-BB was 80% for the region level (499/624; kappa(κ)=0.59) and 86.5% for the patient level (135/156; κ=0.73). Inter-reader agreement was 95% (19/20; κ=0.90) for DSAS on the patient level and 91.3% (73/80; κ=0.81) on the region level for experts. For expert versus novice, inter-reader agreement for DSAS was 87.8% on the patient level (137/156; κ=0.75) and 91.2% on the region level (569/624; κ=0.77).
    Conclusions: The DSAS can be assessed in less than 1 min and has a good diagnostic accuracy and reliability for the diagnosis of GCA. The DSAS can be used immediately in clinical practice.
    MeSH term(s) Humans ; Female ; Aged ; Male ; Giant Cell Arteritis/diagnostic imaging ; Temporal Arteries/diagnostic imaging ; Reproducibility of Results ; Retrospective Studies ; Sensitivity and Specificity ; Arteries
    Language English
    Publishing date 2024-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2812592-7
    ISSN 2056-5933 ; 2056-5933
    ISSN (online) 2056-5933
    ISSN 2056-5933
    DOI 10.1136/rmdopen-2023-003652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cryptosporidium parvum

    Veshkini, Arash / Dengler, Franziska / Bachmann, Lisa / Liermann, Wendy / Helm, Christiane / Ulrich, Reiner / Delling, Cora / Kühn, Christa / Hammon, Harald M

    Frontiers in immunology

    2024  Volume 15, Page(s) 1351427

    Abstract: One of the leading causes of infectious diarrhea in newborn calves is the apicomplexan ... ...

    Abstract One of the leading causes of infectious diarrhea in newborn calves is the apicomplexan protozoan
    MeSH term(s) Animals ; Cattle ; Male ; Humans ; Cryptosporidiosis ; Cryptosporidium parvum/genetics ; Cryptosporidium/genetics ; Transcriptome ; Cattle Diseases/genetics ; Intestinal Mucosa ; Tumor Necrosis Factor-alpha/genetics ; Adaptive Immunity ; Immune System Phenomena
    Chemical Substances Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1351427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Thesis: Die Weisheitszahnentfernung bei 1000 Patienten der Klinik und Poliklinik für Zahn-, Mund- und Kieferheilkunde der Universität zu Köln, Abteilungen für zahnärztliche Chirurgie und Mund-, Kiefer- und Gesichtschirurgie

    Horbert, Harald M.

    1995  

    Author's details vorgelegt von Harald M. Horbert
    Keywords Tooth Extraction ; Molar, Third
    Language German
    Size 123 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Köln, Univ., Diss., 1995
    HBZ-ID HT006648068
    Database Catalogue ZB MED Medicine, Health

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  8. Book ; Thesis: Zur Frage der Desinfektion von Latexhandschuhen

    Hildenbrand, Harald M.

    1994  

    Author's details vorgelegt von Harald M. Hildenbrand
    Language German
    Size 70 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 1994
    HBZ-ID HT006650038
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Heart rate variability: just a surrogate for mean heart rate?

    Stauss, Harald M

    Hypertension (Dallas, Tex. : 1979)

    2014  Volume 64, Issue 6, Page(s) 1184–1186

    MeSH term(s) Animals ; Autonomic Nervous System/physiopathology ; Electrocardiography ; Heart/physiopathology ; Heart Diseases/physiopathology ; Heart Rate/physiology ; Humans
    Language English
    Publishing date 2014-12
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.114.03949
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cryptosporidium parvumcompetes with the intestinal epithelial cells for glucose and impairs systemic glucose supply in neonatal calves

    Franziska Dengler / Harald M. Hammon / Wendy Liermann / Solvig Görs / Lisa Bachmann / Christiane Helm / Reiner Ulrich / Cora Delling

    Veterinary Research, Vol 54, Iss 1, Pp 1-

    2023  Volume 16

    Abstract: Abstract Cryptosporidiosis is one of the main causes of diarrhea in children and young livestock. The interaction of the parasite with the intestinal host cells has not been characterized thoroughly yet but may be affected by the nutritional demand of ... ...

    Abstract Abstract Cryptosporidiosis is one of the main causes of diarrhea in children and young livestock. The interaction of the parasite with the intestinal host cells has not been characterized thoroughly yet but may be affected by the nutritional demand of the parasite. Hence, we aimed to investigate the impact of C. parvum infection on glucose metabolism in neonatal calves. Therefore, N = 5 neonatal calves were infected with C. parvum on the first day of life, whereas a control group was not (N = 5). The calves were monitored clinically for one week, and glucose absorption, turnover and oxidation were assessed using stable isotope labelled glucose. The transepithelial transport of glucose was measured using the Ussing chamber technique. Glucose transporters were quantified on gene and protein expression level using RT-qPCR and Western blot in the jejunum epithelium and brush border membrane preparations. Plasma glucose concentration and oral glucose absorption were decreased despite an increased electrogenic phlorizin sensitive transepithelial transport of glucose in infected calves. No difference in the gene or protein abundance of glucose transporters, but an enrichment of glucose transporter 2 in the brush border was observed in the infected calves. Furthermore, the mRNA for enzymes of the glycolysis pathway was increased indicating enhanced glucose oxidation in the infected gut. In summary, C. parvum infection modulates intestinal epithelial glucose absorption and metabolism. We assume that the metabolic competition of the parasite for glucose causes the host cells to upregulate their uptake mechanisms and metabolic machinery to compensate for the energy losses.
    Keywords Cryptosporidiosis ; GLUT2 ; in vivo ; metabolism ; SGLT1 ; Ussing chamber ; Veterinary medicine ; SF600-1100
    Subject code 570
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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