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  1. Article: Skin Tears in Older People.

    Hardie, Chevannah / Wick, Jeannette Y

    The Senior care pharmacist

    2020  Volume 35, Issue 9, Page(s) 379–387

    Abstract: Skin tears are a common occurrence in older people, though many are unfamiliar with them until late in life. These painful wounds are more likely to occur with age as the skin experiences age-related changes. Numerous factors including declining dermal ... ...

    Abstract Skin tears are a common occurrence in older people, though many are unfamiliar with them until late in life. These painful wounds are more likely to occur with age as the skin experiences age-related changes. Numerous factors including declining dermal thickness and loss of elasticity contribute to their development. Risk increases in patients who need assistance with activities of daily living or who need help transferring from bed or chair. Polypharmacy is a risk factor. Prevention is the best approach, but once skin tears develop, treatment needs to be tailored to the tear's grade.
    MeSH term(s) Activities of Daily Living ; Aged ; Aged, 80 and over ; Elasticity ; Humans ; Lacerations ; Skin ; Soft Tissue Injuries
    Language English
    Publishing date 2020-08-17
    Publishing country United States
    Document type Journal Article
    ISSN 2639-9636
    ISSN 2639-9636
    DOI 10.4140/TCP.n.2020.379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Small-angle neutron scattering from CuCrZr coupons and components.

    Schoofs, F / King, S / Cackett, A J / Leyland, M / Hardie, C

    Journal of applied crystallography

    2021  Volume 54, Issue Pt 5, Page(s) 1394–1402

    Abstract: Small-angle neutron scattering (SANS) is performed to analyse the microstructural state of a reference CuCrZr material with carefully controlled heat treatments, small-scale manufacturing mock-ups of assemblies and high-heat-flux-exposed mock-ups for ... ...

    Abstract Small-angle neutron scattering (SANS) is performed to analyse the microstructural state of a reference CuCrZr material with carefully controlled heat treatments, small-scale manufacturing mock-ups of assemblies and high-heat-flux-exposed mock-ups for fusion reactor components. The information derived from the SANS data corresponds well to existing literature data based on microscopic-scale techniques, but is obtained at millimetre scale with minimal surface preparation. The manufacturing method and high-heat-flux testing conditions are confirmed to have little impact on the microstructural properties, demonstrating the validity of these treatments for scaled-up reactor components.
    Language English
    Publishing date 2021-09-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2020879-0
    ISSN 1600-5767 ; 0021-8898
    ISSN (online) 1600-5767
    ISSN 0021-8898
    DOI 10.1107/S1600576721008311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diagnostic accuracy of magnetic resonance imaging for nerve injury in obstetric brachial plexus injury: protocol for systematic review and meta-analysis.

    Hardie, Claire / Brooks, James / Wade, Ryckie / Teh, Irvin / Bourke, Grainne

    Systematic reviews

    2022  Volume 11, Issue 1, Page(s) 173

    Abstract: Background: Early and accurate clinical diagnosis of the extent of obstetric brachial plexus injury (OBPI) is challenging. The current gold standard for delineating the nerve injury is surgical exploration, and synchronous reconstruction is performed if ...

    Abstract Background: Early and accurate clinical diagnosis of the extent of obstetric brachial plexus injury (OBPI) is challenging. The current gold standard for delineating the nerve injury is surgical exploration, and synchronous reconstruction is performed if indicated. Magnetic resonance imaging (MRI) is a non-invasive method of assessing the anatomy and severity of nerve injury in OBPI but the diagnostic accuracy is unclear. The primary objective of this review is to determine the diagnostic accuracy of MRI in comparison to surgical brachial plexus exploration for detecting root avulsion in children under 5 with OBPI. The secondary objectives are to determine its' diagnostic accuracy for detecting nerve abnormality and detecting pseudomeningocele(s) in this group.
    Methods: This review will be conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA).We will include studies reporting the accuracy of MRI (index test) compared to surgical exploration (reference standard) in detecting any of the three target conditions (root avulsion, any nerve abnormality and pseudomeningocele) in children under five with OBPI. Case reports and studies where the number of true positives, false positives, true negatives and false negatives cannot be derived will be excluded. We plan to search PubMed, Embase and CENTRAL for relevant studies from database inception to 15 June 2022. We will also search grey literature (medRxiv, bioRxiv and Google Scholar) and perform forward and backward citation chasing. Screening and full-text assessment of eligibility will be conducted by two independent reviewers, who will then both extract the relevant data. The QUADAS-2 tool will be used to assess methodological quality and risk of bias of included studies by two reviewers independently. The following test characteristics for the target conditions will be extracted: true positives, false positives, true negatives and false negatives. Estimates of sensitivity and specificity with 95% confidence intervals will be shown in forest plots for each study. If appropriate, summary sensitivities and specificities for target conditions will be obtained via meta-analyses using a bivariate model.
    Discussion: This study will aim to clarify the diagnostic accuracy of MRI for detecting nerve injury in OBPI and define its clinical role.
    Systematic review registration: PROSPERO CRD42021267629.
    MeSH term(s) Brachial Plexus/diagnostic imaging ; Brachial Plexus/injuries ; Child, Preschool ; Humans ; Magnetic Resonance Imaging/methods ; Meta-Analysis as Topic ; Sensitivity and Specificity ; Systematic Reviews as Topic
    Language English
    Publishing date 2022-08-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2662257-9
    ISSN 2046-4053 ; 2046-4053
    ISSN (online) 2046-4053
    ISSN 2046-4053
    DOI 10.1186/s13643-022-02037-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Wound complications following surgery to the lymph nodes: A protocol for a systematic review and meta-analysis.

    Nzenwa, Ikemsinachi C / Iqbal, Hassan A / Hardie, Claire / Smith, George E / Matteucci, Paolo L / Totty, Joshua P

    PloS one

    2022  Volume 17, Issue 8, Page(s) e0272490

    Abstract: Background: Malignancies that spread to the lymph nodes may be identified through surgical biopsy, and treatment of metastatic disease may be through lymph node dissection. These surgeries, however, may be associated with significant adverse outcomes, ... ...

    Abstract Background: Malignancies that spread to the lymph nodes may be identified through surgical biopsy, and treatment of metastatic disease may be through lymph node dissection. These surgeries, however, may be associated with significant adverse outcomes, particularly wound complications, the true incidence of which remains unknown. Multiple studies have reported their individual rates of complications in isolation. The aim of this study will be to systematically evaluate data that presents the incidence of wound complications in patients undergoing these surgeries.
    Methods: We have designed and registered a protocol for a systematic review and meta-analysis of studies presenting incidence data. We will search MEDLINE, EMBASE and CENTRAL for relevant articles. Meta-analysis will be undertaken to synthesise an overall incidence of surgical site infection, wound dehiscence, haematoma and seroma. Subgroup analyses will investigate the effects of anatomical location, primary malignancy and study design on pooled incidence. Risk of bias will be evaluated for each included study using bespoke tools matched to the study design.
    Discussion: The results of this study will provide the incidence of wound complications and secondary complications following lymph node surgery. This will directly impact upon the consent process, and may influence the nature of future research studies aimed at reducing post-operative complications.
    MeSH term(s) Humans ; Lymph Nodes/surgery ; Meta-Analysis as Topic ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Seroma ; Surgical Wound Dehiscence/epidemiology ; Surgical Wound Dehiscence/etiology ; Surgical Wound Infection/complications ; Surgical Wound Infection/etiology ; Systematic Reviews as Topic
    Language English
    Publishing date 2022-08-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0272490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Prevalence and risk factors for nerve injury following shoulder dislocation.

    Hardie, C M / Jordan, R / Forker, O / Fort-Schaale, A / Wade, R G / Jones, J / Bourke, G

    Musculoskeletal surgery

    2022  Volume 107, Issue 3, Page(s) 345–350

    Abstract: Background: The glenohumeral joint dislocation can be associated with major nerve injury. The reported prevalence and risk factors for major nerve injury are variable and this injury can have a severe and life-long impact on the patient. The objectives ... ...

    Abstract Background: The glenohumeral joint dislocation can be associated with major nerve injury. The reported prevalence and risk factors for major nerve injury are variable and this injury can have a severe and life-long impact on the patient. The objectives of this study were to analyse the prevalence of major nerve injury following shoulder dislocation and examine risk factors. Management and outcomes of nerve injury were explored.
    Methods: A 1 year retrospective cohort study of 243 consecutive adults who presented with a shoulder dislocation was performed. Data were collected on patient demographics, timings of investigations, treatment, follow-up, and nerve injury prevalence and management. The primary outcome measure was prevalence of nerve injury. Risk factors for this were analysed using appropriate tests with Stata SE15.1.
    Results: Of 243 patients with shoulder dislocation, 14 (6%) had neurological deficit. Primary dislocation (p = 0.004) and older age (p = 0.02) were significantly associated with major nerve injury. Sex, time to successful reduction and force of injury were not associated with major nerve injury in this cohort. Patients with nerve injury made functional recovery to varying degrees. Recurrent shoulder dislocation was common accounting for 133/243 (55%) attendances.
    Conclusions: Shoulder dislocation requires careful assessment and timely management in the ED. A 6% rate of nerve injury following shoulder dislocation was at the lower border of reported rates (5-55%), and primary dislocation and older age were identified as risk factors for nerve injury. We emphasise the importance of referring patients with suspected major nerve injury to specialist services.
    MeSH term(s) Adult ; Humans ; Shoulder Dislocation/complications ; Shoulder Dislocation/epidemiology ; Retrospective Studies ; Prevalence ; Risk Factors ; Recovery of Function ; Shoulder
    Language English
    Publishing date 2022-11-29
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2495458-5
    ISSN 2035-5114 ; 2035-5106
    ISSN (online) 2035-5114
    ISSN 2035-5106
    DOI 10.1007/s12306-022-00769-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Receipt of mastectomy and adjuvant radiotherapy following breast conserving surgery (BCS) in New Zealand women with BCS-eligible breast cancer, 2010-2015: an observational study focusing on ethnic differences.

    Bartholomew, Karen / Ghafel, Mazin / Tin Tin, Sandar / Aye, Phyu S / Elwood, J Mark / Hardie, Claire / Scott, Nina / Kidd, Jacquie / Ramsaroop, Reena / Campbell, Ian

    BMC cancer

    2023  Volume 23, Issue 1, Page(s) 766

    Abstract: Background: Women with early breast cancer who meet guideline-based criteria should be offered breast conserving surgery (BCS) with adjuvant radiotherapy as an alternative to mastectomy. New Zealand (NZ) has documented ethnic disparities in screening ... ...

    Abstract Background: Women with early breast cancer who meet guideline-based criteria should be offered breast conserving surgery (BCS) with adjuvant radiotherapy as an alternative to mastectomy. New Zealand (NZ) has documented ethnic disparities in screening access and in breast cancer treatment pathways. This study aimed to determine whether, among BCS-eligible women, rates of receipt of mastectomy or radiotherapy differed by ethnicity and other factors.
    Methods: The study assessed management of women with early breast cancer (ductal carcinoma in situ [DCIS] and invasive stages I-IIIA) registered between 2010 and 2015, extracted from the recently consolidated New Zealand Breast Cancer Registry (now Te Rēhita Mate Ūtaetae NZBCF National Breast Cancer Register). Specific criteria were applied to determine women eligible for BCS. Uni- and multivariable analyses were undertaken to examine differences by demographic and clinicopathological factors with a primary focus on ethnicity (Māori, Pacific, Asian, and Other; the latter is defined as NZ European, Other European, and Middle Eastern Latin American and African).
    Results: Overall 22.2% of 5520 BCS-eligible women were treated with mastectomy, and 91.1% of 3807 women who undertook BCS received adjuvant radiotherapy (93.5% for invasive cancer, and 78.3% for DCIS). Asian ethnicity was associated with a higher mastectomy rate in the invasive cancer group (OR 2.18; 95%CI 1.72-2.75), compared to Other ethnicity, along with older age, symptomatic diagnosis, advanced stage, larger tumour, HER2-positive, and hormone receptor-negative groups. Pacific ethnicity was associated with a lower adjuvant radiotherapy rate, compared to Other ethnicity, in both invasive and DCIS groups, along with older age, symptomatic diagnosis, and lower grade tumour in the invasive group. Both mastectomy and adjuvant radiotherapy rates decreased over time. For those who did not receive radiotherapy, non-referral by a clinician was the most common documented reason (8%), followed by patient decline after being referred (5%).
    Conclusion: Rates of radiotherapy use are high by international standards. Further research is required to understand differences by ethnicity in both rates of mastectomy and lower rates of radiotherapy after BCS for Pacific women, and the reasons for non-referral by clinicians.
    MeSH term(s) Female ; Humans ; Breast Neoplasms/epidemiology ; Breast Neoplasms/ethnology ; Breast Neoplasms/radiotherapy ; Breast Neoplasms/surgery ; Carcinoma, Intraductal, Noninfiltrating/epidemiology ; Carcinoma, Intraductal, Noninfiltrating/ethnology ; Carcinoma, Intraductal, Noninfiltrating/radiotherapy ; Carcinoma, Intraductal, Noninfiltrating/surgery ; Maori People/statistics & numerical data ; Mastectomy/statistics & numerical data ; Mastectomy, Segmental/statistics & numerical data ; New Zealand/epidemiology ; Radiotherapy, Adjuvant/statistics & numerical data ; Pacific Island People/statistics & numerical data ; Asian/statistics & numerical data ; European People/statistics & numerical data ; Middle Eastern People/statistics & numerical data ; African People/statistics & numerical data
    Language English
    Publishing date 2023-08-17
    Publishing country England
    Document type Comparative Study ; Journal Article ; Observational Study
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-023-11248-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pharmacists' Experiences, Perceptions, and Knowledge of Direct-to-Consumer Prescription Coupons.

    Gernant, Stephanie A / Polomoff, Christina M / Marsh, Julise / Martineau, Sarah / Hardie, Chevannah / Jeffery, Sean M

    Journal of managed care & specialty pharmacy

    2020  Volume 26, Issue 9, Page(s) 1130–1137

    Abstract: Background: Despite widespread use of manufacturer-sponsored prescription drug coupons and pharmacy network discount cards (i.e., direct-to-consumer prescription coupons), little is known about community pharmacists' experiences, perceptions, and ... ...

    Abstract Background: Despite widespread use of manufacturer-sponsored prescription drug coupons and pharmacy network discount cards (i.e., direct-to-consumer prescription coupons), little is known about community pharmacists' experiences, perceptions, and knowledge of coupon cards.
    Objective: To identify community pharmacists' experiences, perceptions, and knowledge of prescription coupons.
    Methods: An 11-item telephonic survey was conducted from August 2018 to March 2019. Eligible respondents included English-speaking pharmacists employed during the survey period in a community pharmacy physically located in Connecticut. Data were analyzed via descriptive statistics and one-way analysis of variance (ANOVA). One-way ANOVAs were conducted to test the relationship between the respondents' practice types, the average daily volume of coupons processed, and the average time needed to process each coupon. The responses were based on a 5-point Likert scale and dichotomized to enable interpretation of the results.
    Results: There were 240 surveys completed from an eligible pool of 691 community pharmacy sites (34.7% response rate). Respondents representing 60 different businesses located across 123 of the state's 282 major ZIP codes, representing 83.5% of the state's population. Respondents overwhelmingly held positive perceptions of the ability of prescription coupons to increase patients' medication access (91.7 %) and reduce out-of-pocket costs (93.3%). However, respondents also believed patients have trouble paying for prescriptions once coupons expire (70.8%). When questioned about privacy practices, 57.5% of respondents believed that it is illegal to "sell patients' information" (i.e., with no distinction made between protected health information and any other information), while another 25.8% declined to answer, citing they did not know. Only 20.8% (n = 50) of respondents knew that community pharmacies could see lowered reimbursement from accepting network drug discount cards, and 40.4% (n = 97) knew that pharmaceutical manufacturers can cover the difference in patients' copay costs. Approximately 10% of respondents believed (incorrectly) that discounts from pharmacy network discount cards were covered via patients' prescription insurance and/or the third-party discount card vendor companies (7.9% and 3.3%, respectively). Respondents believed patients received prescription coupons most often from the internet or mail (77.1%), their prescribers (62.9%), or from their own community pharmacies (33.3%). Finally, on average, respondents processed 14.6 (SD 19.8) coupons per day and required 4.8 (SD 4.3) minutes for each claim.
    Conclusions: As far as we know, this is the first exploration of community pharmacists' experiences, perceptions, and knowledge of direct-to-consumer prescription coupons. Results show that, while community pharmacists overwhelmingly hold positive perceptions towards prescription coupons and drug discount cards, there is an opportunity to increase general understanding of the differences in business practices between manufacturer-sponsored prescription drug coupons and pharmacy network discount cards. Community pharmacies also spend a significant amount of time processing coupon claims.
    Disclosures: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors declare no relevant conflicts of interest or financial relationships. This study was presented as a poster at the 2019 American Society of Health Systems Pharmacists Midyear Clinical Meeting during December 8-12, 2019, in Las Vegas, NV.
    MeSH term(s) Attitude of Health Personnel ; Community Pharmacy Services ; Drug Industry/economics ; Health Services Accessibility/economics ; Humans ; Pharmacists/statistics & numerical data ; Prescription Drugs/economics ; Reimbursement Mechanisms ; Surveys and Questionnaires ; Time Factors
    Chemical Substances Prescription Drugs
    Language English
    Publishing date 2020-07-31
    Publishing country United States
    Document type Journal Article
    ISSN 2376-1032
    ISSN (online) 2376-1032
    DOI 10.18553/jmcp.2020.26.9.1130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pedagogical practices that influence professional identity formation in baccalaureate nursing education: A scoping review.

    Simmonds, Anne / Nunn, Alexandra / Gray, Mikaela / Hardie, Catherine / Mayo, Samantha / Peter, Elizabeth / Richards, Jessie

    Nurse education today

    2020  Volume 93, Page(s) 104516

    Abstract: Objectives: The purpose of this review was to identify pedagogical practices that contribute to professional identity formation in undergraduate nursing education and to map the components of professional identity described within these practices.: ... ...

    Abstract Objectives: The purpose of this review was to identify pedagogical practices that contribute to professional identity formation in undergraduate nursing education and to map the components of professional identity described within these practices.
    Design: A scoping review using a six-stage methodological framework was used to capture a range of evidence describing how professional identity has been conceptualized and integrated into nursing curriculum.
    Data sources: Databases searched included: Ovid MEDLINE: Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid MEDLINE® Daily and Ovid MEDLINE® 1946-Present, EBSCO CINAHL (1981 to present), OVID PsycINFO (1806 to Present), ProQuest ERIC, ASSIA, and Sociological Abstracts. Additional studies were identified by scanning the reference lists of relevant articles.
    Review methods: The study team collaboratively designed the data charting table and two coauthors independently screened the studies using Covidence software. Qualitative content analysis was used to categorize learning outcomes into five components of professional identity that were associated with pedagogical practices identified in the studies.
    Results: A total of 114 peer-reviewed journal articles were initially charted. Articles were categorized as intervention studies (46, 40%), perspective studies (40, 35%), theoretical papers (17, 15%), or reviews (11, 10%). To ensure feasibility in collating and reporting the results, the review focused on the 46 empirical intervention studies that described associations between pedagogical practices and professional identity formation learning outcomes for students.
    Conclusions: This scoping review illustrates the range of contexts in which nursing students learn, the multidimensional nature of identity formation, as well as the breadth of pedagogical practices and learning outcomes that guide course design. The results can be used to inform future curriculum planning and to identify focused research questions to extend our understanding of evidence-based teaching practices supporting professional identity formation.
    MeSH term(s) Curriculum ; Education, Nursing, Baccalaureate ; Humans ; Learning ; Nurse's Role ; Professionalism ; Students, Nursing/psychology
    Keywords covid19
    Language English
    Publishing date 2020-06-27
    Publishing country Scotland
    Document type Journal Article ; Review
    ZDB-ID 1062570-7
    ISSN 1532-2793 ; 0260-6917
    ISSN (online) 1532-2793
    ISSN 0260-6917
    DOI 10.1016/j.nedt.2020.104516
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of statin and aspirin use on toxicity and pathological complete response rate of neo-adjuvant chemoradiation for rectal cancer.

    Hardie, Claire / Jung, Yoonsuh / Jameson, Michael

    Asia-Pacific journal of clinical oncology

    2016  Volume 12, Issue 2, Page(s) 167–173

    Abstract: Aim: To retrospectively evaluate the potential impact of statin and aspirin use on acute toxicity and pathological complete response (pCR) rate in rectal cancer patients receiving neo-adjuvant long-course radiation therapy (LCRT) with concurrent ... ...

    Abstract Aim: To retrospectively evaluate the potential impact of statin and aspirin use on acute toxicity and pathological complete response (pCR) rate in rectal cancer patients receiving neo-adjuvant long-course radiation therapy (LCRT) with concurrent chemotherapy.
    Methods: A retrospective review was performed of all patients undergoing neo-adjuvant LCRT for rectal adenocarcinoma at the Regional Cancer Treatment Service between 1 September 2007 and 1 June 2011. Data obtained include demographic details; date and radiological TNM stage at diagnosis; medication taken at time of RT; toxicity during LCRT; and surgical histology to determine if a pCR was obtained following LCRT.
    Results: Neo-adjuvant LCRT was administered to 142 patients for rectal cancer during this period; concurrent chemotherapy was omitted in 13 due to significant comorbidities. TNM stage was 2 or 3 radiologically at diagnosis in 127 (89.4%) of patients. At the time of LCRT, 23% were taking a statin and 25% were taking aspirin. Of 135 assessable patients, 34 (13%) achieved a pCR at surgery. On logistic regression, pCR was not significantly associated with the use of chemotherapy, statins, aspirin, other NSAIDs, T-stage or N-stage. There was no significant correlation between statin or aspirin use with bladder or rectal toxicity. Actuarial time to maximum rectal toxicity was not different in statin users or nonusers.
    Conclusion: In contrast to other larger retrospective series, this study did not find improvements in toxicity or pCR rate through statin or aspirin use in rectal cancer patients undergoing LCRT. Their potential benefits in this setting would be best studied prospectively in a large randomized trial.
    MeSH term(s) Adenocarcinoma/drug therapy ; Adenocarcinoma/pathology ; Adenocarcinoma/radiotherapy ; Adult ; Aged ; Aged, 80 and over ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Aspirin/therapeutic use ; Chemoradiotherapy, Adjuvant ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Male ; Middle Aged ; Rectal Neoplasms/drug therapy ; Rectal Neoplasms/pathology ; Rectal Neoplasms/radiotherapy ; Retrospective Studies ; Young Adult
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2016-06
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2187409-8
    ISSN 1743-7563 ; 1743-7555
    ISSN (online) 1743-7563
    ISSN 1743-7555
    DOI 10.1111/ajco.12468
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Hormone replacement therapy: the risks and benefits of treatment.

    Hardie, C / Bain, C / Walters, M

    The journal of the Royal College of Physicians of Edinburgh

    2009  Volume 39, Issue 4, Page(s) 324–326

    Abstract: Several recent large studies have provoked concern among both health professionals and the general public regarding the safety of hormone replacement therapy (HRT). This article provides a review of the current literature surrounding the risks and ... ...

    Abstract Several recent large studies have provoked concern among both health professionals and the general public regarding the safety of hormone replacement therapy (HRT). This article provides a review of the current literature surrounding the risks and benefits of HRT in postmenopausal women, and how the data can be applied safely in everyday clinical practice.
    Language English
    Publishing date 2009-12
    Publishing country Scotland
    Document type Journal Article
    ISSN 1478-2715
    ISSN 1478-2715
    DOI 10.4997/JRCPE.2009.408
    Database MEDical Literature Analysis and Retrieval System OnLINE

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