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  1. Article: Phlegmasia Dolens.

    Hardin, John

    Western journal of medicine and surgery

    2024  Volume 5, Issue 4, Page(s) 265–266

    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Remarks on Fracture of the Cranium.

    Hardin, John

    Western journal of medicine and surgery

    2024  Volume 9, Issue 3, Page(s) 203–219

    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Observations on a Peculiar Form of Bilious Fever.

    Hardin, John

    Western journal of medicine and surgery

    2024  Volume 3, Issue 2, Page(s) 104–112

    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: On the Treatment of Dysentery.

    Hardin, John

    Western journal of medicine and surgery

    2024  Volume 8, Issue 1, Page(s) 1–7

    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Management of Transverse Presentations of the Fœtus: Read before the Louisville Medical Club.

    Hardin, John

    The North American medico-chirurgical review

    2023  Volume 1, Issue 1, Page(s) 73–78

    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: TIAM-1 regulates polarized protrusions during dorsal intercalation in the

    Zhu, Yuyun / Hardin, Jeff

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Mediolateral cell intercalation is a morphogenetic strategy used throughout animal development to reshape tissues. Dorsal intercalation in the : Summary statement: TIAM-1 activates the Rac pathway to promote protrusion formation via its GEF domain, ... ...

    Abstract Mediolateral cell intercalation is a morphogenetic strategy used throughout animal development to reshape tissues. Dorsal intercalation in the
    Summary statement: TIAM-1 activates the Rac pathway to promote protrusion formation via its GEF domain, while its N-terminal domains suppress ectopic protrusions during dorsal intercalation in the
    Language English
    Publishing date 2023-07-24
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.07.24.550374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: TIAM-1 regulates polarized protrusions during dorsal intercalation in the Caenorhabditis elegans embryo through both its GEF and N-terminal domains.

    Zhu, Yuyun / Tesone, Zoe / Tan, Minyi / Hardin, Jeff

    Journal of cell science

    2024  Volume 137, Issue 5

    Abstract: Mediolateral cell intercalation is a morphogenetic strategy used throughout animal development to reshape tissues. Dorsal intercalation in the Caenorhabditis elegans embryo involves the mediolateral intercalation of two rows of dorsal epidermal cells to ... ...

    Abstract Mediolateral cell intercalation is a morphogenetic strategy used throughout animal development to reshape tissues. Dorsal intercalation in the Caenorhabditis elegans embryo involves the mediolateral intercalation of two rows of dorsal epidermal cells to create a single row that straddles the dorsal midline, and thus is a simple model to study cell intercalation. Polarized protrusive activity during dorsal intercalation requires the C. elegans Rac and RhoG orthologs CED-10 and MIG-2, but how these GTPases are regulated during intercalation has not been thoroughly investigated. In this study, we characterized the role of the Rac-specific guanine nucleotide exchange factor (GEF) TIAM-1 in regulating actin-based protrusive dynamics during dorsal intercalation. We found that TIAM-1 can promote formation of the main medial lamellipodial protrusion extended by intercalating cells through its canonical GEF function, whereas its N-terminal domains function to negatively regulate the generation of ectopic filiform protrusions around the periphery of intercalating cells. We also show that the guidance receptor UNC-5 inhibits these ectopic filiform protrusions in dorsal epidermal cells and that this effect is in part mediated via TIAM-1. These results expand the network of proteins that regulate basolateral protrusive activity during directed rearrangement of epithelial cells in animal embryos.
    MeSH term(s) Animals ; Actins/metabolism ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/metabolism ; Epithelial Cells/metabolism ; Guanine Nucleotide Exchange Factors/metabolism ; Receptors, Cell Surface ; T-Lymphoma Invasion and Metastasis-inducing Protein 1/metabolism
    Chemical Substances Actins ; Caenorhabditis elegans Proteins ; Guanine Nucleotide Exchange Factors ; Receptors, Cell Surface ; T-Lymphoma Invasion and Metastasis-inducing Protein 1 ; TIAM-1 protein, C elegans ; UNC-5 protein, C elegans (149592-60-9)
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2993-2
    ISSN 1477-9137 ; 0021-9533
    ISSN (online) 1477-9137
    ISSN 0021-9533
    DOI 10.1242/jcs.261509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Everyday Ethical Comportment: An Evolutionary Concept Analysis.

    Hardin, Joshua

    The Journal of nursing education

    2018  Volume 57, Issue 8, Page(s) 460–468

    Abstract: Background: The formation of everyday ethical comportment is an essential part of nursing education in the 21st century, but the concept is more abstract and confusing than the dominant bioethical models frequently used in nursing education.: Method: ...

    Abstract Background: The formation of everyday ethical comportment is an essential part of nursing education in the 21st century, but the concept is more abstract and confusing than the dominant bioethical models frequently used in nursing education.
    Method: The purpose of this analysis is to explore the concept of everyday ethical comportment and determine whether the concept remains viable for nursing as a discipline. Rodgers' method of evolutionary concept analysis guided a systematic literature review. Following PRISMA guidelines, 32 articles containing the keywords everyday ethical comportment were identified, and 20 are included in this study.
    Results: The analysis identified four critical attributes of everyday ethical comportment (embodiment, skilled relational know-how, caring, and salience). The concept's surrogate and related terms, antecedents, and consequences were also identified.
    Conclusion: Everyday ethical comportment is underrepresented in the literature. Although it remains viable for nursing as a discipline, the concept's future sustainability is questionable. [J Nurs Educ. 2018;57(8):460-468.].
    MeSH term(s) Concept Formation ; Education, Nursing ; Ethics, Nursing/education ; Humans
    Language English
    Publishing date 2018-08-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410686-6
    ISSN 1938-2421 ; 0148-4834
    ISSN (online) 1938-2421
    ISSN 0148-4834
    DOI 10.3928/01484834-20180720-03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Embedded Narratives: Metabolic Disorders and Pentecostal Conversion in Samoa.

    Hardin, Jessica

    Medical anthropology quarterly

    2018  Volume 32, Issue 1, Page(s) 22–41

    Abstract: Drawing from interviews and participant observation, this article explores the intersection of diagnosis of metabolic disorders and religious conversion among Pentecostal Christians in Samoa by analyzing what I call embedded narratives--conversion ... ...

    Abstract Drawing from interviews and participant observation, this article explores the intersection of diagnosis of metabolic disorders and religious conversion among Pentecostal Christians in Samoa by analyzing what I call embedded narratives--conversion narratives embedded in illness narratives. Drawing from ethnographic data, I examine how using conversion narrative conventions enabled those living with metabolic disorders to narrate behavior change in a culturally and socially valorized way. By embedding their narratives, I suggest those living with metabolic disorders shifted the object of care from a disease process toward the creation of a religious life and in turn transformed the risks associated with metabolic disorders, including diet, exercise, and pharmaceutical use into moral risks associated with everyday religious life. In these cases, Pentecostal conversion created possible scripts for changing health practices, managing stress, and shifting resource use in the name of religious commitment, providing insights into how self-care can be an expression of religious practice.
    MeSH term(s) Anthropology, Medical ; Christianity/psychology ; Female ; Humans ; Male ; Metabolic Diseases/ethnology ; Metabolic Diseases/psychology ; Metabolic Diseases/therapy ; Narration ; Samoa/ethnology ; Self Care
    Language English
    Publishing date 2018
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1038242-2
    ISSN 1548-1387 ; 0745-5194
    ISSN (online) 1548-1387
    ISSN 0745-5194
    DOI 10.1111/maq.12368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Lamellipodin homologue MIG-10 is not essential for dorsal intercalation in the embryonic epidermis of the

    Serre, Joel M / Hardin, Jeff

    microPublication biology

    2022  Volume 2022

    Abstract: Dorsal intercalation of the embryonic epidermis in ... ...

    Abstract Dorsal intercalation of the embryonic epidermis in the
    Language English
    Publishing date 2022-02-03
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.000522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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