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Book: Current occupational & environmental medicine

Ladou, Joseph / Harrison, Joseph

(Current diagnosis & treatment ; A Lange medical book)

2014

Title variant	Current occupational and environmental medicine
Author's details	ed. Joseph LaDou ; Robert J. Harrison
Series title	Current diagnosis & treatment A Lange medical book
Language	English
Size	XII, 911 S. : Ill.
Edition	5. ed.
Publisher	McGraw Hill Education Medical
Publishing place	New York u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT018379044
ISBN	978-0-07-180815-6 ; 0-07-180815-9
Database	Catalogue ZB MED Medicine, Health

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2014 A 3435	available for loan (reading room)	Lesesaal EG

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Article ; Online: Designing Nudges for Success in Health Care.

Harrison, Joseph D / Patel, Mitesh S

AMA journal of ethics

2020 Volume 22, Issue 9, Page(s) E796–801

Abstract: Nudges are subtle changes to the design of the environment or the framing of information that can influence our behaviors. There is significant potential to use nudges in health care to improve patient outcomes and transform health care delivery. However, ...

Abstract	Nudges are subtle changes to the design of the environment or the framing of information that can influence our behaviors. There is significant potential to use nudges in health care to improve patient outcomes and transform health care delivery. However, these interventions must be tested and implemented using a systematic approach. In this article, we describe several ways to design nudges for success by focusing on optimizing and fitting them into the clinical workflow, engaging the right stakeholders, and rapid experimentation.
MeSH term(s)	Delivery of Health Care ; Humans
Language	English
Publishing date	2020-09-01
Publishing country	United States
Document type	Journal Article
ISSN	2376-6980
ISSN (online)	2376-6980
DOI	10.1001/amajethics.2020.796
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Missed Opportunity: Universal School-Based Mental Health Literacy Programs.

Fadus, Matthew C / Harrison, Joseph D

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

2019 Volume 43, Issue 4, Page(s) 457–460

MeSH term(s)	Adolescent ; Awareness ; Health Literacy ; Humans ; Mental Disorders/prevention & control ; Mental Disorders/psychology ; Psychiatry ; Public-Private Sector Partnerships ; Schools ; Students/psychology
Language	English
Publishing date	2019-02-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1045331-3
ISSN	1545-7230 ; 1042-9670
ISSN (online)	1545-7230
ISSN	1042-9670
DOI	10.1007/s40596-019-01036-8
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Article: Dewatering of cellulose nanofibrils using ultrasound

Ringania, Udita / Harrison, Joseph / Moon, Robert J. / Bhamla, M. Saad

Cellulose. 2022 July, v. 29, no. 10

2022

Abstract: Although cellulose nanomaterials have promising properties and performance in a wide application space, one hinderance to their wide scale industrial application has been associated with their economics of dewatering and drying and the ability to ... ...

Abstract	Although cellulose nanomaterials have promising properties and performance in a wide application space, one hinderance to their wide scale industrial application has been associated with their economics of dewatering and drying and the ability to redisperse them back into suspension without introducing agglomerates or lose of yield. The present work investigates the dewatering of aqueous suspensions of cellulose nanofibrils (CNFs) using ultrasound as a potentially low-cost, non-thermal, and scalable alternative to traditional heat-based drying methods such as spray drying. Specifically, we use vibrating mesh transducers to develop a direct-contact mode ultrasonic dewatering platform to remove water from CNF suspensions in a continuous manner. We demonstrate that the degree of dewatering is modulated by the number of transducers, their spatial configuration, and the flow rate of the CNF suspension. Water removal of up to 72 wt.% is achieved, corresponding to a final CNF concentration of 11 wt.% in 30 min using a two-transducer configuration. To evaluate the redispersibility of the dewatered CNF material, we use a microscopic analysis to quantify the morphology of the redispersed CNF suspension. By developing a custom software pipeline to automate image analysis, we compare the histograms of the dimensions of the redispersed dewatered fibrils with the original CNF samples and observe no significant difference, suggesting that no agglomeration is induced due to ultrasonic dewatering. We also perform SEM analysis to evaluate the nanoscale morphology of these fibrils showing a width range of 20 nm–4 um. We estimate that this ultrasound dewatering technique is also energy-efficient, consuming up to 36% less energy than the enthalpy of evaporation per kilogram of water. Together with the inexpensive cost of transducers (< $1), the potential for scaling up in parallel flow configurations, and excellent redispersion of the dewatered CNFs, our work offers a proof-of-concept of a sustainable CNF dewatering system, that addresses the shortcomings of existing techniques.
Keywords	cellulose ; cellulose nanofibers ; dewatering ; direct contact ; energy efficiency ; enthalpy ; evaporation ; image analysis ; industrial applications ; ultrasonics
Language	English
Dates of publication	2022-07
Size	p. 5575-5591.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	1496831-9
ISSN	1572-882X ; 0969-0239
ISSN (online)	1572-882X
ISSN	0969-0239
DOI	10.1007/s10570-022-04626-2
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Inside-Out Design of Zinc-Binding Proteins with Non-Native Backbones.

Guffy, Sharon L / Pulavarti, Surya V S R K / Harrison, Joseph / Fleming, Drew / Szyperski, Thomas / Kuhlman, Brian

Biochemistry

2023 Volume 62, Issue 3, Page(s) 770–781

Abstract: ... ...

Abstract	The
MeSH term(s)	Amino Acid Sequence ; Ligands ; Retrospective Studies ; Proteins/chemistry ; Zinc ; Protein Conformation
Chemical Substances	Ligands ; Proteins ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2023-01-12
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1108-3
ISSN	1520-4995 ; 0006-2960
ISSN (online)	1520-4995
ISSN	0006-2960
DOI	10.1021/acs.biochem.2c00595
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Article ; Online: Eligibility of emergency department patients for public benefit programs.

Harrison, Joseph / McDermott, Grace / Dixon, Erica L / Mehta, Michael / Haider, Aliza / Rareshide, Charles / Southwick, Lauren / Agarwal, Anish K / Merchant, Raina M / Kilaru, Austin S

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

2024

Language	English
Publishing date	2024-03-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	1329813-6
ISSN	1553-2712 ; 1069-6563
ISSN (online)	1553-2712
ISSN	1069-6563
DOI	10.1111/acem.14870
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Article ; Online: Methane yields during anaerobic co-digestion of animal manure with other feedstocks: A meta-analysis.

Ma, Guiling / Ndegwa, Pius / Harrison, Joseph H / Chen, Yanting

The Science of the total environment

2020 Volume 728, Page(s) 138224

Abstract: Anaerobic co-digestion of animal manure with other feedstocks (aka co-digestion) is increasingly being used to enhance methane yield and organic waste management. The benefits accruing from co-digestions compared to mono-digestions, however, vary greatly ...

Abstract	Anaerobic co-digestion of animal manure with other feedstocks (aka co-digestion) is increasingly being used to enhance methane yield and organic waste management. The benefits accruing from co-digestions compared to mono-digestions, however, vary greatly in the literature. The goal of this research was to use meta-analysis to critically compare methane yields between mono- and co-digestions and identify relevant factors (co-substrate type, substrate dose, carbon to nitrogen (C/N) ratio, volatile solids (VS), substrate pH, organic loading rate (OLR), and hydraulic retention time (HRT)) contributing to methane yield. Published studies (n = 64 representing 384 case-studies) with sufficient detail on methane yield were identified for the meta-analysis. Analysis indicated that co-digestion of animal manure with other feedstocks significantly increased methane yield (249 L kg
MeSH term(s)	Anaerobiosis ; Animals ; Biofuels ; Bioreactors ; Cattle ; Manure ; Methane ; Swine ; Waste Management
Chemical Substances	Biofuels ; Manure ; Methane (OP0UW79H66)
Language	English
Publishing date	2020-03-28
Publishing country	Netherlands
Document type	Journal Article ; Meta-Analysis ; Review
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2020.138224
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Article: Leveraging behavioral economics and implementation science to engage patients at risk for suicide in mental health treatment: a pilot study protocol.

Khazanov, Gabriela Kattan / Jager-Hyman, Shari / Harrison, Joseph / Candon, Molly / Buttenheim, Alison / Pieri, Matteo F / Oslin, David W / Wolk, Courtney Benjamin

Pilot and feasibility studies

2022 Volume 8, Issue 1, Page(s) 181

Abstract: Background: Primary care is an ideal setting to connect individuals at risk for suicide to follow-up care; however, only half of the patients referred from the primary care attend an initial mental health visit. We aim to develop acceptable, feasible, ... ...

Abstract	Background: Primary care is an ideal setting to connect individuals at risk for suicide to follow-up care; however, only half of the patients referred from the primary care attend an initial mental health visit. We aim to develop acceptable, feasible, low-cost, and effective new strategies to increase treatment initiation among at-risk individuals identified in primary care. Methods: We will conduct a multi-phase, mixed-methods study. First, we will conduct a chart review study by using administrative data, including medical records, to identify characteristics of primary care patients at risk for suicide who do or do not attend an initial mental health visit following a referral. Second, we will conduct a mixed methods study by using direct observations and qualitative interviews with key stakeholders (N = 65) to understand barriers and facilitators to mental health service initiation among at-risk individuals. Stakeholders will include patients with suicidal ideation referred from primary care who do and do not attend a first mental health visit, primary care and behavioral health providers, and individuals involved in the referral process. We also will collect preliminary self-report and behavioral data regarding potential mechanisms of behavior change (i.e., self-regulation and social support) from patients. Third, we will leverage these findings, relevant frameworks, and the extant literature to conduct a multi-arm, non-randomized feasibility trial. During this trial, we will rapidly prototype and test strategies to support attendance at initial mental health visits. Strategies will be developed with subject matter experts (N = 10) and iteratively pilot tested (~5 patients per strategy) and refined. Research will be completed in the Penn Integrated Care Program (PIC), which includes fourteen primary care clinics in Philadelphia that provide infrastructure for electronic referrals, patient communication, and data access. Discussion: We will leverage frameworks and methods from behavioral economics and implementation science to develop strategies to increase mental health treatment initiation among individuals at risk for suicide identified in primary care. This project will lead to an evaluation of these strategies in a fully powered randomized trial and contribute to improvements in access to and engagement in mental health services for individuals at risk for suicide. Trial registration: ClinicalTrials.gov Identifier: NCT05021224.
Language	English
Publishing date	2022-08-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2809935-7
ISSN	2055-5784
ISSN	2055-5784
DOI	10.1186/s40814-022-01131-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effect of stearic or oleic acid on milk performance and energy partitioning when fed in diets with low and high rumen-active unsaturated fatty acids in early lactation.

Yanting, Chen / Ma, Guiling / Harrison, Joseph H / Block, Elliot

Journal of animal science

2019 Volume 97, Issue 11, Page(s) 4647–4656

Abstract: This experiment was conducted to determine the effects of stearic acid (SA; C18:0) or rumen-protected oleic acid (OA; C18:1 cis-9) on milk performance and energy partitioning of early lactation cows when supplemented in diets with low and high level of ... ...

Abstract	This experiment was conducted to determine the effects of stearic acid (SA; C18:0) or rumen-protected oleic acid (OA; C18:1 cis-9) on milk performance and energy partitioning of early lactation cows when supplemented in diets with low and high level of rumen unsaturated fatty acids (RUFA). In low RUFA experiment (LRUFA), FA supplement rich in either SA or calcium salts OA was added to a basal diet with a low concentration of RUFA (0.75% vs. 1.4%, LRUFA-SA vs. LRUFA-OA). In high RUFA experiment (HRUFA), 2% soybean oil was added to the diet fed in the LRUFA experiment. In each experiment, 30 multiparous cows were blocked by parity and predicted transmitting ability for milk yield and were randomly fed 1 of 2 treatment diets from 2 to 13 wk postpartum. In the LRUFA experiment, LRUFA-SA had 2.4 kg/d more dry matter intake (DMI) (P < 0.01), 3.8 kg/d more energy-corrected milk (P < 0.01), and 0.3% units more milk fat percentage (P < 0.01) and 0.2 kg/d more milk fat yield (P < 0.01). Dietary treatments did not affect body weight, energy balance, and energy intake partitioning into milk, maintenance, and body tissues (P > 0.1). In the HRUFA experiment, HRUFA-SA had 1.4 kg/d more DMI (P = 0.03) but similar milk and milk components yields (P > 0.1). HRUFA-SA had a tendency to gain more body weight (P = 0.07) and had more positive energy balance (P = 0.01) and decreased gross feed efficiency (milk yield/DMI) (P = 0.01). Consistently, HRUFA-SA increased intake energy partitioning into body tissues (P = 0.02) and decreased energy partitioning into milk (P = 0.01). In summary, SA supplementation had more DMI relative to OA, but the effects on milk and milk fat production were different and affected by the level of RUFA in the basal diet. In application, SA supplementation was more effective to improve milk production when included in the basal diet with the low RUFA.
MeSH term(s)	Animals ; Body Weight ; Cattle/physiology ; Diet/veterinary ; Dietary Supplements/analysis ; Energy Metabolism/drug effects ; Fatty Acids, Unsaturated/administration & dosage ; Female ; Glycolipids/analysis ; Glycoproteins/analysis ; Lactation ; Lipid Droplets ; Milk/chemistry ; Milk/metabolism ; Oleic Acid/administration & dosage ; Postpartum Period ; Pregnancy ; Rumen/metabolism ; Soybean Oil/administration & dosage ; Stearic Acids/administration & dosage
Chemical Substances	Fatty Acids, Unsaturated ; Glycolipids ; Glycoproteins ; Stearic Acids ; milk fat globule ; Oleic Acid (2UMI9U37CP) ; stearic acid (4ELV7Z65AP) ; Soybean Oil (8001-22-7)
Language	English
Publishing date	2019-09-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	390959-1
ISSN	1525-3163 ; 0021-8812
ISSN (online)	1525-3163
ISSN	0021-8812
DOI	10.1093/jas/skz304
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Article ; Online: Usability of Wearable Devices to Remotely Monitor Sleep Patterns Among Patients With Ischemic Heart Disease: Observational Study.

Fortunato, Michael / Adusumalli, Srinath / Chokshi, Neel / Harrison, Joseph / Rareshide, Charles / Patel, Mitesh

JMIR formative research

2020 Volume 4, Issue 4, Page(s) e14508

Abstract: Background: There is growing interest in using wearable devices to remotely monitor patient behaviors. However, there has been little evaluation of how often these technologies are used to monitor sleep patterns over longer term periods, particularly ... ...

Abstract	Background: There is growing interest in using wearable devices to remotely monitor patient behaviors. However, there has been little evaluation of how often these technologies are used to monitor sleep patterns over longer term periods, particularly among more high-risk patients. Objective: The goal of the research was to evaluate the proportion of time that patients with ischemic heart disease used wearable devices to monitor their sleep and identify differences in characteristics of patients with higher versus lower use. Methods: We evaluated wearable device data from a previously conducted clinical trial testing the use of wearable devices with personalized goal-setting and financial incentives. Patients with ischemic heart disease established a sleep baseline and were then followed for 24 weeks. The proportion of days that sleep data was collected was compared over the 24 weeks and by study arm. Characteristics of patients were compared to groups with high, low, or no sleep data. Results: The sample comprised 99 patients with ischemic heart disease, among which 79% (78/99) used the wearable device to track their sleep. During the 6-month trial, sleep data were collected on 60% (10,024/16,632) of patient-days. These rates declined over time from 77% (4292/5544) in months 1 and 2 to 58% (3188/5544) in months 3 and 4 to 46% (2544/5544) in months 5 and 6. Sleep data were collected at higher rates among the intervention group compared with control (67% vs 55%, P<.001). In the main intervention period (months 3 and 4), patients with higher rates of sleep data were on average older (P=.03), had a history of smoking (P=.007), and had higher rates of commercial health insurance (P=.03). Conclusions: Among patients with ischemic heart disease in a physical activity trial, a high proportion used wearable devices to track their sleep; however, rates declined over time. Future research should consider larger evaluations coupled with behavioral interventions. Trial registration: ClinicalTrials.gov NCT02531022; https://clinicaltrials.gov/ct2/show/NCT02531022.
Language	English
Publishing date	2020-04-07
Publishing country	Canada
Document type	Journal Article
ISSN	2561-326X
ISSN (online)	2561-326X
DOI	10.2196/14508
Database	MEDical Literature Analysis and Retrieval System OnLINE

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