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  1. Article ; Online: Optical, piezoelectric and mechanical properties of xylenol orange doped ADP single crystals for NLO applications

    Sahil Goel / Nidhi Sinha / Harsh Yadav / Abhilash J. Joseph / Abid Hussain / Binay Kumar

    Arabian Journal of Chemistry, Vol 13, Iss 1, Pp 146-

    2020  Volume 159

    Abstract: Single crystals of pure and xylenol orange (XO; C31H32N2O13S) dye doped (0.01, 0.05 and 0.1 mol%) ammonium dihydrogen phosphate (ADP; NH4H2PO4) were grown by slow evaporation method with the vision to improve the properties of pure ammonium dihydrogen ... ...

    Abstract Single crystals of pure and xylenol orange (XO; C31H32N2O13S) dye doped (0.01, 0.05 and 0.1 mol%) ammonium dihydrogen phosphate (ADP; NH4H2PO4) were grown by slow evaporation method with the vision to improve the properties of pure ammonium dihydrogen phosphate crystal. The theoretical morphology of the grown crystals was drawn using Bravais–Friedel–Donnay–Harker (BFDH) law. The selective nature of xylenol orange dye to selectively stain the particular growth sectors of ADP crystal was studied. The structural analysis of as grown crystals was carried out using powder XRD study. The identification of the functional groups present in the ADP material was done using Fourier transform infrared (FTIR) spectroscopy. The linear optical study on pure and dye doped crystals was carried out using UV–vis–NIR spectroscopy. The optical band gap, extinction coefficient, refractive index and optical conductivity were calculated using the transmittance spectra for all the samples. In photoluminescence studies, the blue emission intensity got quenched and an orange emission at 597 nm was seen as a result of XO doping. The thermal stability and decomposition temperature of ADP crystal were found to decrease as an effect of dye doping. The piezoelectric charge coefficient, SHG conversion efficiency, mechanical strength and wettability were also enhanced as a result of XO dye doping. Keywords: Nonlinear optical materials, Dye-doped crystals, Optical properties, Piezoelectricity, Mechanical properties
    Keywords Chemistry ; QD1-999
    Subject code 535
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Diagnostic accuracy of dual energy CT in the assessment of traumatic bone marrow edema of lower limb and its correlation with MRI

    Harsh Yadav / Sachin Khanduri / Poonam Yadav / Sushma Pandey / Vivek Kumar Yadav / Shahla Khan

    Indian Journal of Radiology and Imaging, Vol 30, Iss 01, Pp 59-

    2020  Volume 63

    Abstract: Background: Bone marrow edema is assumed to be caused as a result of trabecular microfractures that are detected by MRI. As MRI is not widely available in countries like India, this study aims to encourage the use of DECT in detection of bone edema as ... ...

    Abstract Background: Bone marrow edema is assumed to be caused as a result of trabecular microfractures that are detected by MRI. As MRI is not widely available in countries like India, this study aims to encourage the use of DECT in detection of bone edema as evidence with comparable efficiency to MRI. Aim: To assess the diagnostic accuracy of dual-energy CT in detecting bone marrow edema in patients of trauma of lower limb and correlate it with MRI. Setting and Design: It is a cross-sectional study. Materials and Methods: The study included 40 patients of age 15–70 years irrespective of sex. All the patients of lower extremity trauma underwent DECT and MRI evaluation after clinical evaluation. All the images were postprocessed on a work station and were further evaluated by a radiologist. Results: Mean attenuation at fractured site observed by Dual energy CT was found to be significantly higher as compared to that at adjacent site (170.75 ± 33.99 vs. 19.73 ± 22.50 HU). The sensitivity and specificity of dual energy CT as compared to MRI in detecting bone marrow edema were 94.1% and 91.3%, respectively. Of the 40 cases enrolled in the study, agreement of MRI and Dual energy CT was observed in 37 (92.5%). Conclusion: Dual energy CT can be an effective alternative to MRI in the detection of bone marrow edema in patients of lower limb trauma. Dual energy CT can also be used in patients in whom MRI is contraindicated.
    Keywords bone marrow edema ; dect ; lower limb ; trauma ; mri ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 610 ; 616
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Test Tube Tooth

    Preeti Yadav / Mohammed Tahir / Harsh Yadav / Rakshit Sureka / Aarti Garg

    Journal of Clinical and Diagnostic Research, Vol 10, Iss 6, Pp ZE01-ZE

    The Next Big Thing

    2016  Volume 03

    Abstract: Unlike some vertebrates and fishes, humans do not have the capacity for tooth regeneration after the loss of permanent teeth. Although artificial replacement with removable dentures, fixed prosthesis and implants is possible through advances in the field ...

    Abstract Unlike some vertebrates and fishes, humans do not have the capacity for tooth regeneration after the loss of permanent teeth. Although artificial replacement with removable dentures, fixed prosthesis and implants is possible through advances in the field of prosthetic dentistry, it would be ideal to recreate a third set of natural teeth to replace lost dentition. For many years now, researchers in the field of tissue engineering have been trying to bioengineer dental tissues as well as whole teeth. In order to attain a whole tooth through dental engineering, that has the same or nearly same biological, mechanical and physical properties of a natural tooth, it’s necessary to deal with all the cells and tissues which are concerned with the formation, maintenance and repair of the tooth. In this article we review the steps involved in odontogenesis or organogenesis of a tooth and progress in the bioengineering of a whole tooth.
    Keywords bioengineering ; odontogenesis ; regeneration ; stem cells ; Medicine ; R
    Subject code 670
    Language English
    Publishing date 2016-06-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Antibiotic sensitivity and resistance in nosocomial infection in medical and surgical intensive care units of a tertiary care hospital in north India

    Harsh Yadav / Gopal Jhalani / Kalpana Sharma / Shivankan Kakkar / Vishnu Gupta / Arvind Verma

    International Journal of Basic & Clinical Pharmacology, Vol 5, Iss 5, Pp 2164-

    2016  Volume 2167

    Abstract: Background: Antibiotic resistance threatens the health of many throughout the world. It is a common problem in the ICU patients who acquire nosocomial infections. Critically ill ICU patients are most vulnerable for developing multidrug resistant ... ...

    Abstract Background: Antibiotic resistance threatens the health of many throughout the world. It is a common problem in the ICU patients who acquire nosocomial infections. Critically ill ICU patients are most vulnerable for developing multidrug resistant nosocomial infections. Methods: Hospital based, cross sectional, descriptive type of observational study involving 311 patients admitted in ICU who were studied for development of nosocomial infections. Results: In this study, the nosocomial infection rate among ICU patients was 32.79%. The commonest organism isolated from all samples were E. coli., Acinetobacter spp., Pseudomonas sp., CONS and Staph. aureus. In these samples, it was found that E. coli was most commonly resistant to Imipenem (93.8%) and Meropenem (93.8%). Majority of CONS was resistant to Nitrofurantoin (81.0%). Klebsiella sp. was most commonly resistant to Ceftriaxone (94.4%). Pseudomonas was commonly resistant to Imipenem (94.1%) and Meropenem (94.1%). Acinetobacter sp. was resistant commonly to Amikacin (90%) and Gentamicin (90%). Staph. Aureus was mostly resistant to Amikacin (90%), Gentamicin (90%) and Cotrimoxazole (90%). Conclusions: Nosocomial infections affect about 1/3rd of the patients in ICUs. Development of antibiotic resistance to commonly used drugs becomes a major deterrent to patient outcome, increasing duration of patient stay as well as expense. Strict infection control measures like universal precautions and stringent adherence to hand washing practices; formulation of antibiotic policy; Surveillance activities, appointment of infection control practitioners; might be required for the same for which further research is advocated. [Int J Basic Clin Pharmacol 2016; 5(5.000): 2164-2167]
    Keywords Antibiotic resistance ; Nosocomial infection ; Antibiotic policy ; Therapeutics. Pharmacology ; RM1-950 ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2016-10-01T00:00:00Z
    Publisher Medip Academy
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Comparative evaluation of efficacy and safety of primaquine sustained-release tablets v/s primaquine conventional tablets in Treatment and prevention of relapse of plasmodium vivax malaria

    Vishnu Kumar Gupta / Gopal Jhalani / Harsh Yadav / Arvind Verma / Shivankan Kakkar

    International Journal of Basic & Clinical Pharmacology, Vol 5, Iss 6, Pp 2664-

    2016  Volume 2668

    Abstract: Background: Malaria is one of the most important parasitic disease of human. In India 60-65% of infections are due to P.vivax and 35-40% are due to P.falciparum Malaria is an acute, recurrent and sometimes chronic vector borne protozoan disease which has ...

    Abstract Background: Malaria is one of the most important parasitic disease of human. In India 60-65% of infections are due to P.vivax and 35-40% are due to P.falciparum Malaria is an acute, recurrent and sometimes chronic vector borne protozoan disease which has worldwide distribution in tropical and subtropical regions The role of Primaquine is well established in the prevention of relapse of P.vivax malaria. Primaquine has a narrow therapeutic range and short half-life that requires daily administration upto 2 weeks, resulting in poor compliance Methods: Randomized control trial, which involved 100 patients of P.vivax Malaria Patient in medical ward of mahatma Gandhi hospital attached to S N medical college 'Jodhpur. All patient in this study received chloroquine for 3 days (10mg of base per kg followed by 5mg /kg 6-8 hours later and 5 mg/kg on each of the two days, total 25mg/kg over 3days and divided in three groups viz.Group 1 taken Primaquine 15 mg tab for 14 days (n=34), Group 2 taken Primaquine 15 mg SR tab for 14 days (n=33),Group 3 taken Primaquine 30 mg SR tab for 7 days and placebo for next 7 days. Results: In this study, Efficacy and compliance of Primaquine 30 mg SR for 7 days was found greater than the conventional Primaquine tab. and Primaquine 15 mg SR tab for 14 day. Adverse effect of primaquine 30 mg SR tab for 7 days was found lesser than conventional Primaquine tab 15 mg as well as Primaquine 15 mg SR tab. Conclusions: As Malaria is very prevalent in India which causes significant mortality and morbidity in Indian population. Use of Primaquine 30 mg SR tab has good compliance, efficacy as well as lesser adverse effect. [Int J Basic Clin Pharmacol 2016; 5(6.000): 2664-2668]
    Keywords Malaria ; P. Vivax ; Primaquine SR ; Randomized control trial ; Therapeutics. Pharmacology ; RM1-950 ; Medicine ; R
    Subject code 630
    Language English
    Publishing date 2016-12-01T00:00:00Z
    Publisher Medip Academy
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Biomedical Biopolymers, their Origin and Evolution in Biomedical Sciences

    Preeti Yadav / Harsh Yadav / Veena Gowri Shah / Gaurav Shah / Gaurav Dhaka

    Journal of Clinical and Diagnostic Research, Vol 9, Iss 9, Pp ZE21-ZE

    A Systematic Review

    2015  Volume 25

    Abstract: Biopolymers provide a plethora of applications in the pharmaceutical and medical applications. A material that can be used for biomedical applications like wound healing, drug delivery and tissue engineering should possess certain properties like ... ...

    Abstract Biopolymers provide a plethora of applications in the pharmaceutical and medical applications. A material that can be used for biomedical applications like wound healing, drug delivery and tissue engineering should possess certain properties like biocompatibility, biodegradation to non-toxic products, low antigenicity, high bio-activity, processability to complicated shapes with appropriate porosity, ability to support cell growth and proliferation and appropriate mechanical properties, as well as maintaining mechanical strength. This paper reviews biodegradable biopolymers focusing on their potential in biomedical applications. Biopolymers most commonly used and most abundantly available have been described with focus on the properties relevant to biomedical importance.
    Keywords biodegradable ; biomedical applications ; polymers ; Medicine ; R
    Language English
    Publishing date 2015-09-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Assessment of morbidity pattern, quality of life and awareness of government facilities among elderly population in South India

    Nitin Joseph / Maria Nelliyanil / Sriraksha R Nayak / Vyom Agarwal / Arjun Kumar / Harsh Yadav / Gourav Ramuka / Kshirabdhi Tanaya Mohapatra

    Journal of Family Medicine and Primary Care, Vol 4, Iss 3, Pp 405-

    2015  Volume 410

    Abstract: Background: This study was done to assess the determinants of morbidity pattern, quality of life (QoL) and awareness of elderly about various government schemes and social security legislations. Materials and Methods: Data was collected by house to house ...

    Abstract Background: This study was done to assess the determinants of morbidity pattern, quality of life (QoL) and awareness of elderly about various government schemes and social security legislations. Materials and Methods: Data was collected by house to house survey among participants aged 60 years and above using a structured interview schedule. The QoL was assessed using Kannada version of WHOQOL-BREF instrument following language validation. Results: Mean age of 206 participants was 69.6±6.7 years. Half of them were males and majority were graduates 54 (26.2%). Morbidity was present among 194 (94.2%) participants (95% CI 89.5-98.9%), most common being hypertension 96 (46.6%). Morbid conditions were seen more among less educated (P = 0.007). Only 68 (33%) were under medical insurance coverage, 17 (8.3%) were under old age government pension and 74 (35.9%) were under retirement pension scheme. Social relationships, psychological health and environmental domain scores were associated with socio-economic status. Social relationship domain score was significantly better among well educated participants and those without morbidities. Level of ambulation was significantly associated with QoL scores in all domains (P < 0.001). Majority of the participants 132 (64.1%) had moderate level of awareness about government facilities for senior citizens. Awareness level was significantly better among males (P < 0.001), well educated (P < 0.001), better socio-economic status respondents (P < 0.001) and those currently working (P = 0.026). Conclusion: Health status of elderly needs improvement which would also improve their QoL. Awareness about various government schemes needs to be enhanced to improve its utilization. The results of this study are expected to help policy makers in planning comprehensive services for elderly residing in this area.
    Keywords Awareness ; community based study ; geriatric population ; government facilities ; morbidity ; quality of life ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Localization of Impacted Canines

    Surubhi Kumar / Praveen Mehrotra / Jitendra Bhagchandani / Ashish Singh / Aarti Garg / Snehi Kumar / Ashish Sharma / Harsh Yadav

    Journal of Clinical and Diagnostic Research, Vol 9, Iss 1, Pp ZE11-ZE

    2015  Volume 14

    Abstract: Impaction of maxillary canines is a frequently encountered clinical problem. The impaction of canine can be prevented in some situations if the canine displacement is diagnosed in the early mixed dentition period and this would be extremely useful for ... ...

    Abstract Impaction of maxillary canines is a frequently encountered clinical problem. The impaction of canine can be prevented in some situations if the canine displacement is diagnosed in the early mixed dentition period and this would be extremely useful for the clinician. Hence, it is very important to focus on the means of early diagnosis and interception of this clinical situation. In the present article, the different modalities used to diagnose the impacted canine are reviewed with an insight into current 3-D modalities.
    Keywords diagnosis ; early displaced canines ; impacted canines ; radiographs ; Medicine ; R
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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