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  1. Book ; Thesis: Bestimmung der effektiven Halbwertszeit bei der Radioiodtherapie benigner Schilddrüsenerkrankungen mit 131Iod unter Berücksichtigung diverser Einflussfaktoren

    Hartmann, Tobias Rupert Cyprian

    2016  

    Author's details vorgelegt von Tobias Rupert Cyprian Hartmann
    Subject code 610
    Language German
    Size 107 Blätter, Illustrationen
    Publishing place Freiburg (Breisgau)
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Albert-Ludwigs-Universität Freiburg (Breisgau), 2016
    Note Im Titel ist "131" hochgestellt.
    HBZ-ID HT019346622
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Use-Case-Oriented Evaluation of Wireless Communication Technologies for Advanced Underground Mining Operations.

    Theissen, Marius / Kern, Leonhard / Hartmann, Tobias / Clausen, Elisabeth

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 7

    Abstract: This work aims to give an overview of wireless communication technologies (WCT) for underground applications. Difficulties regarding the harsh mining environment and operational constraints for WCT implementation and use are discussed. Selected ... ...

    Abstract This work aims to give an overview of wireless communication technologies (WCT) for underground applications. Difficulties regarding the harsh mining environment and operational constraints for WCT implementation and use are discussed. Selected technologies are then classified regarding underground mining-specific use cases in advanced mining operations. Use-case-based application categories such as 'automation and teleoperation', 'tracking and tracing' and 'Long-Range Underground Monitoring (LUM)' are defined. The use cases determine requirements for the operational suitability and also quantify evaluation criteria for the evaluation of WCT. The result is a comparison by category of the wireless technologies, which underlines potentials of different technologies for defined use cases, but it can be concluded that the technology always has to be evaluated within the use case and operational constraints.
    Language English
    Publishing date 2023-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23073537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online ; Thesis: Zusammenhänge zwischen der Lipidhomöostase und den molekularen Mechanismen der Alzheimer Krankheit

    Hubig, Hannah [Verfasser] / Hartmann, Tobias [Akademischer Betreuer]

    2022  

    Author's details Hannah Hubig ; Betreuer: Tobias Hartmann
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Saarländische Universitäts- und Landesbibliothek
    Publishing place Saarbrücken
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Book ; Online ; Thesis: Über die Regulation der Calcium-Homöostase und den Einfluss von STIM-Proteinen auf die Alzheimer-Pathologie

    Streidenberger, Olga [Verfasser] / Hartmann, Tobias [Akademischer Betreuer]

    2022  

    Author's details Olga Streidenberger ; Betreuer: Tobias Hartmann
    Keywords Naturwissenschaften ; Science
    Subject code sg500
    Language German
    Publisher Saarländische Universitäts- und Landesbibliothek
    Publishing place Saarbrücken
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Book ; Online ; Thesis: Der bidirektionale Zusammenhang zwischen Sulfatiden und den molekularen Mechanismen der Alzheimer-Erkrankung

    Zimmer, Valerie-Christin [Verfasser] / Hartmann, Tobias [Akademischer Betreuer]

    2022  

    Author's details Valerie-Christin Zimmer ; Betreuer: Tobias Hartmann
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Saarländische Universitäts- und Landesbibliothek
    Publishing place Saarbrücken
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  6. Article: Meta-analysis of nutrient budgets in organic farms across Europe

    Reimer, Marie / Möller, Kurt / Hartmann, Tobias Edward

    Organic agriculture. 2020 Dec., v. 10, no. Supplement 1

    2020  

    Abstract: Nutrient supply to organic farms is a highly discussed topic in Europe, due to the restricted availability of external fertilizer resources and the use of contentious inputs. To optimize the flow of nutrients throughout the organic farming system, it is ... ...

    Abstract Nutrient supply to organic farms is a highly discussed topic in Europe, due to the restricted availability of external fertilizer resources and the use of contentious inputs. To optimize the flow of nutrients throughout the organic farming system, it is firstly necessary to obtain valid data on the nutrient status of organic farms. Nutrient budgets are a valid tool to investigate the nutrient demand or surplus of a system. However, there is currently no comprehensive overview of nutrient budgets of European organic farms. We therefore carried out a meta-analysis on 56 individual studies that reported either farm-gate or soil surface budgets. The analysis showed an imbalance between nutrients, a general surplus of nitrogen (45 kg N ha⁻¹ year⁻¹ [95% confidence interval (CI) 30, 61]), magnesium (16 kg Mg ha⁻¹ year⁻¹ [− 9, 40]) and sulfur (45 kg S ha⁻¹ year⁻¹ [− 29, 118]), a balanced phosphorus budget (0 kg P ha⁻¹ year⁻¹ [− 2, 2]), and a deficit for potassium (− 12 kg K ha⁻¹ year⁻¹ [− 21, − 3]). We observed large differences between farms that could be partly explained by farm type and budgeting method. Arable and mixed farms showed lower nitrogen, phosphor, magnesium, and sulfur budgets than dairy/beef farms or even vegetable farms, while all farm types besides dairy/beef farms showed deficits for K budgets. Further, farm-gate budget studies yielded higher budgets than soil surface budgets. Variations between studied countries could also be detected, but the coverage and comparability are low due to differences in studied farm types and budgeting method.
    Keywords beef ; confidence interval ; farms ; magnesium ; meta-analysis ; nitrogen ; organic production ; phosphorus ; potassium ; soil ; sulfur ; vegetables ; Europe
    Language English
    Dates of publication 2020-12
    Size p. 65-77.
    Publishing place Springer Netherlands
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2587049-X
    ISSN 1879-4246 ; 1879-4238
    ISSN (online) 1879-4246
    ISSN 1879-4238
    DOI 10.1007/s13165-020-00300-8
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Modeling the underlying biological processes in Alzheimer's disease using a multivariate competing risk joint model.

    van Oudenhoven, Floor M / Swinkels, Sophie H N / Hartmann, Tobias / Rizopoulos, Dimitris

    Statistics in medicine

    2022  Volume 41, Issue 17, Page(s) 3421–3433

    Abstract: Many clinical trials repeatedly measure several longitudinal outcomes on patients. Patient follow-up can discontinue due to an outcome-dependent event, such as clinical diagnosis, death, or dropout. Joint modeling is a popular choice for the analysis of ... ...

    Abstract Many clinical trials repeatedly measure several longitudinal outcomes on patients. Patient follow-up can discontinue due to an outcome-dependent event, such as clinical diagnosis, death, or dropout. Joint modeling is a popular choice for the analysis of this type of data. Using example data from a prodromal Alzheimer's disease trial, we propose a new type of multivariate joint model in which longitudinal brain imaging outcomes and memory impairment ratings are allowed to be associated both with time to open-label medication and dropout, and where the brain imaging outcomes may also directly affect the memory impairment ratings. Existing joint models for multivariate longitudinal outcomes account for the correlation between the longitudinal outcomes through the random effects, often by assuming a multivariate normal distribution. However, for these models, it is difficult to interpret how the longitudinal outcomes affect each other. We model the dependence between the longitudinal outcomes differently so that a first longitudinal outcome affects a second one. Specifically, for each longitudinal outcome, we use a linear mixed-effects model to estimate its trajectory, where, for the second longitudinal outcome, we include the linear predictor of the first outcome as a time-varying covariate. This facilitates an easy and direct interpretation of the association between the longitudinal outcomes and provides a framework for latent mediation analysis to understand the underlying biological processes. For the trial considered here, we found that part of the intervention effect is mediated through hippocampal brain atrophy. The proposed joint models are fitted using a Bayesian framework via MCMC simulation.
    MeSH term(s) Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/drug therapy ; Bayes Theorem ; Biological Phenomena ; Humans ; Linear Models ; Longitudinal Studies ; Models, Statistical
    Language English
    Publishing date 2022-05-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 843037-8
    ISSN 1097-0258 ; 0277-6715
    ISSN (online) 1097-0258
    ISSN 0277-6715
    DOI 10.1002/sim.9425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Thesis: The Mo-containing and NAD+-dependent formate dehydrogenase from Rhodobacter capsulatus

    Hartmann, Tobias

    2014  

    Author's details von Tobias Hartmann
    Language English
    Size 8 [Bl.], 143 S., Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Potsdam, 2014
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Book: Wie Unternehmen ihr Naturkapital ökonomisch erfassen

    Hartmann, Tobias

    Bestandsaufnahme und Handlungsempfehlungen

    2014  

    Author's details Autor: Tobias Hartmann
    Keywords Umweltbericht ; Ökosystem ; Artenvielfalt ; Kosten-Nutzen-Analyse ; Multinationales Unternehmen ; Welt
    Language Undetermined
    Size 62 Seiten, Illustrationen, 30 cm
    Edition Stand: April 2014
    Publisher Global Nature Fund (GNF), Internationale Stiftung für Umwelt und Natur
    Publishing place Radolfzell
    Document type Book
    Database ECONomics Information System

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  10. Book ; Online: Code Cache Optimizations for Dynamically Compiled Languages

    Hartmann, Tobias

    2014  

    Keywords KODIERUNG (SOFTWARE ENGINEERING) ; COMPILER (PROGRAMMIERSPRACHEN) ; CODING (SOFTWARE ENGINEERING) ; COMPILERS (PROGRAMMING LANGUAGES) ; info:eu-repo/classification/ddc/004 ; Data processing ; computer science
    Language English
    Publisher ETH-Zürich
    Publishing country ch
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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