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  1. Article ; Online: Heparin monitoring during extracorporeal membrane oxygenation: the effect of dextran sulfate on anti-Xa assay.

    Hammami, Emna / Stiel, Laure / Palpacuer, Clément / Harzallah, Inès

    Research and practice in thrombosis and haemostasis

    2023  Volume 7, Issue 7, Page(s) 102196

    Language English
    Publishing date 2023-08-30
    Publishing country United States
    Document type Journal Article
    ISSN 2475-0379
    ISSN (online) 2475-0379
    DOI 10.1016/j.rpth.2023.102196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sea-blue histiocytes in the bone marrow of a patient with Niemann-Pick disease type C2.

    Fenomanana, Jocia / Harzallah, Inès / Martzolff, Lionel / Debliquis, Agathe

    Annales de biologie clinique

    2020  Volume 78, Issue 4, Page(s) 463–464

    MeSH term(s) Anemia/diagnosis ; Anemia/etiology ; Anemia/pathology ; Bone Marrow/pathology ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/pathology ; Female ; Histiocytes/pathology ; Humans ; Middle Aged ; Mobility Limitation ; Niemann-Pick Disease, Type C/complications ; Niemann-Pick Disease, Type C/diagnosis ; Niemann-Pick Disease, Type C/pathology ; Sea-Blue Histiocyte Syndrome/complications ; Sea-Blue Histiocyte Syndrome/diagnosis ; Sea-Blue Histiocyte Syndrome/pathology ; Weight Loss/physiology
    Language English
    Publishing date 2020-05-26
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 418098-7
    ISSN 1950-6112 ; 0003-3898
    ISSN (online) 1950-6112
    ISSN 0003-3898
    DOI 10.1684/abc.2020.1569
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.203: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Frequency of lupus anticoagulant in COVID-19 patients.

    Harzallah, Inès / Debliquis, Agathe / Drénou, Bernard

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 18, Issue 10, Page(s) 2778

    MeSH term(s) Antiphospholipid Syndrome ; COVID-19 ; Humans ; Lupus Coagulation Inhibitor ; Pandemics ; SARS-CoV-2
    Chemical Substances Lupus Coagulation Inhibitor
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.14937
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    Zs.A 5805: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 295: Show issues

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  4. Article ; Online: Lupus anticoagulant is frequent in patients with Covid-19: Response to reply.

    Harzallah, Inès / Debliquis, Agathe / Drénou, Bernard

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 18, Issue 9, Page(s) E3–E4

    Keywords covid19
    Language English
    Publishing date 2020-06-03
    Publishing country England
    Document type Letter
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.14980
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    Zs.A 5805: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 295: Show issues

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  5. Article ; Online: Lupus anticoagulant is frequent in patients with Covid-19.

    Harzallah, Inès / Debliquis, Agathe / Drénou, Bernard

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 18, Issue 8, Page(s) 2064–2065

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Lupus Coagulation Inhibitor ; Pandemics ; Pneumonia ; Pneumonia, Viral ; Prognosis ; SARS-CoV-2
    Chemical Substances Lupus Coagulation Inhibitor
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.14867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5805: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 295: Show issues

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  6. Article ; Online: Bundles of Auer rods in mature neutrophils in an acute myeloid leukaemia patient with inv(16)(p13.1q22) CBFB-MYH 11.

    Rakotoarivelo, Zolalaina Huberthine / Lefebvre, Thomas / Lamarque, Mathilde / Harzallah, Inès / Debliquis, Agathe

    British journal of haematology

    2022  Volume 200, Issue 4, Page(s) 398

    MeSH term(s) Humans ; Neutrophils ; Leukemia, Myeloid, Acute/genetics ; Oncogene Proteins, Fusion/genetics ; Inclusion Bodies ; Chromosome Inversion ; Core Binding Factor beta Subunit
    Chemical Substances Oncogene Proteins, Fusion ; CBFB protein, human ; Core Binding Factor beta Subunit
    Language English
    Publishing date 2022-11-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.18559
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    Uh III Zs.182: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Acquired Thrombotic Thrombocytopenic Purpura After BNT162b2 COVID-19 Vaccine: Case Report and Literature Review.

    Hammami, Emna / Lamarque, Mathilde / Aujoulat, Olivier / Debliquis, Agathe / Drénou, Bernard / Harzallah, Inès

    Laboratory medicine

    2022  Volume 53, Issue 6, Page(s) e145–e148

    Abstract: Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy that is deadly if not treated promptly. The treatment of choice in patients presenting with TTP is plasma exchanges. However, immunosuppressive therapy and caplacizumab have ... ...

    Abstract Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy that is deadly if not treated promptly. The treatment of choice in patients presenting with TTP is plasma exchanges. However, immunosuppressive therapy and caplacizumab have significantly improved outcomes in TTP. This microangiopathy is classically divided into 2 entities: hereditary and acquired TTP (aTTP), caused by an autoantibody against ADAMTS 13. We present a case study of a patient wth TTP occurring after a second dose of the BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine along with a review of the literature. A 55-year-old patient presented with gastrointestinal symptoms, anemia, and severe thrombocytopenia. The blood film revealed the presence of schistocytes. A diagnosis of aTTP was established because the patient had severe ADAMTS 13 deficiency and autoantibodies against ADAMTS 13 were positive. This episode occurred 10 days after the patient received the COVID-19 vaccine. The patient received plasma exchanges, prednisone, rituximab, and caplacizumab and achieved complete remission. Ten patients with aTTP induced by the COVID-19 vaccine have been reported in the literature. Most of these situations occurred after the second dose of COVID-19 vaccine, and 7 patients were noted to have received the BNT162b2 vaccine. Caplacizumab was used in 6 patients, and complete remission was achieved in 8 patients.
    MeSH term(s) Humans ; Middle Aged ; Purpura, Thrombotic Thrombocytopenic ; ADAMTS13 Protein ; COVID-19 Vaccines/adverse effects ; BNT162 Vaccine ; COVID-19 ; Autoantibodies
    Chemical Substances ADAMTS13 Protein (EC 3.4.24.87) ; COVID-19 Vaccines ; BNT162 Vaccine ; Autoantibodies
    Language English
    Publishing date 2022-04-27
    Publishing country England
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 391758-7
    ISSN 1943-7730 ; 0007-5027
    ISSN (online) 1943-7730
    ISSN 0007-5027
    DOI 10.1093/labmed/lmac016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1013: Show issues Location:
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  8. Article: Severe Perinatal Presentations of Günther's Disease: Series of 20 Cases and Perspectives.

    Goudet, Claire / Ged, Cécile / Petit, Audrey / Desage, Chloe / Mahe, Perrine / Salhi, Aicha / Harzallah, Ines / Blouin, Jean-Marc / Mercie, Patrick / Schmitt, Caroline / Poli, Antoine / Gouya, Laurent / Barlogis, Vincent / Richard, Emmanuel

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 1

    Abstract: 1) Background: Congenital erythropoietic porphyria (CEP), named Günther's disease, is a rare recessive type of porphyria, resulting from deficient uroporphyrinogen III synthase (UROS), the fourth enzyme of heme biosynthesis. The phenotype ranges from ... ...

    Abstract (1) Background: Congenital erythropoietic porphyria (CEP), named Günther's disease, is a rare recessive type of porphyria, resulting from deficient uroporphyrinogen III synthase (UROS), the fourth enzyme of heme biosynthesis. The phenotype ranges from extremely severe perinatal onset, with life-threatening hemolytic anaemia, to mild or moderate cutaneous involvement in late-onset forms. This work reviewed the perinatal CEP cases recorded in France in order to analyse their various presentations and evolution. (2) Methods: Clinical and biological data were retrospectively collected through medical and published records. (3) Results: Twenty CEP cases, who presented with severe manifestations during perinatal period, were classified according to the main course of the disease: antenatal features, acute neonatal distress and postnatal diagnosis. Antenatal symptoms (seven patients) were mainly hydrops fetalis, hepatosplenomegaly, anemia, and malformations. Six of them died prematurely. Five babies showed acute neonatal distress, associated with severe anemia, thrombocytopenia, hepatosplenomegaly, liver dysfunction, and marked photosensitivity leading to diagnosis. The only two neonates who survived underwent hematopoietic stem cell transplantation (HSCT). Common features in post-natal diagnosis (eight patients) included hemolytic anemia, splenomegaly, skin sensitivity, and discoloured teeth and urine. All patients underwent HSCT, with success for six of them, but with fatal complications in two patients. The frequency of the missense variant named C73R is striking in antenatal and neonatal presentations, with 9/12 and 7/8 independent alleles, respectively. (4) Conclusions: The most recent cases in this series are remarkable, as they had a less fatal outcome than expected. Regular transfusions from the intrauterine period and early access to HSCT are the main objectives.
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14010130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Frequency of lupus anticoagulant in Covid-19 patients

    Harzallah, Inès / Debliquis, Agathe / Drénou, Bernard

    J. thromb. haemost

    Abstract: We have recently published in the Journal of Thrombosis and Haemostasis the presence of lupus anticoagulant (LAC) at high frequency in Covid-19 patients (Harzallah et al.1 ). Bowles et al.2 and Helms et al.3 have confirmed these results in new ... ...

    Abstract We have recently published in the Journal of Thrombosis and Haemostasis the presence of lupus anticoagulant (LAC) at high frequency in Covid-19 patients (Harzallah et al.1 ). Bowles et al.2 and Helms et al.3 have confirmed these results in new publications. Tang4 has reported discordant data. He has found that very few tested covid-19 patients had positive LAC in a small series (n=12). Bowles et al. have found that LAC were positive in 91% of patients (n=34) with high activated partial thromboplastin time (aPTT).
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32470207
    Database COVID19

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