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  1. Article: Computerized misinterpretation of QT interval in 12-lead electrocardiogram and its clinical consequences: A case of recurrent syncope.

    Hasegawa, Kanae / Fukuoka, Yoshitomo / Ohno, Seiko / Horie, Minoru / Tada, Hiroshi

    publication RETRACTED

    Journal of arrhythmia

    2023  Volume 39, Issue 2, Page(s) 227–230

    Abstract: Don't blindly accept the automated assessment of electrocardiogram. It is important to raise long QT syndrome to the differential diagnosis of repeated syncope. ...

    Abstract Don't blindly accept the automated assessment of electrocardiogram. It is important to raise long QT syndrome to the differential diagnosis of repeated syncope.
    Language English
    Publishing date 2023-01-30
    Publishing country Japan
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2696593-8
    ISSN 1883-2148 ; 1880-4276
    ISSN (online) 1883-2148
    ISSN 1880-4276
    DOI 10.1002/joa3.12817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Arrhythmogenic superior vena cava manifesting after a right-sided pneumonectomy and mediastinal lymph node dissection.

    Hasegawa, Kanae / Miyazaki, Shinsuke / Okada, Akitoshi / Ishida, Tomokazu / Tada, Hiroshi

    Journal of arrhythmia

    2022  Volume 39, Issue 1, Page(s) 84–87

    Abstract: No case of AF ablation after right-sided pneumonectomy has been reported, presumably because the pneumonectomy renders the ablation procedure more difficult than lobectomy because of the marked mediastinal displacement. In the case of catheter ablation ... ...

    Abstract No case of AF ablation after right-sided pneumonectomy has been reported, presumably because the pneumonectomy renders the ablation procedure more difficult than lobectomy because of the marked mediastinal displacement. In the case of catheter ablation of AF after right-sided pneumonectomy, it is extremely important to insert a mapping catheter not only into the PV but also into the SVC to accurately diagnose the site of abnormal electrical activity.
    Language English
    Publishing date 2022-12-27
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2696593-8
    ISSN 1883-2148 ; 1880-4276
    ISSN (online) 1883-2148
    ISSN 1880-4276
    DOI 10.1002/joa3.12804
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  3. Article ; Online: Intracardiac thrombi fluttering like hair in the wind at VT ablation.

    Hasegawa, Kanae / Powers, Edward M / Yoneda, Zachary T / Richardson, Travis D / Stevenson, William G

    Journal of cardiovascular electrophysiology

    2023  Volume 34, Issue 11, Page(s) 2403–2405

    Abstract: Introduction: Intracardiac echocardiography (ICE) reveals mobile thrombus on implantable electronic device leads in some patients undergoing electrophysiologic procedures.: Methods: ICE was performed in a patient undergoing ventricular tachycardia ( ... ...

    Abstract Introduction: Intracardiac echocardiography (ICE) reveals mobile thrombus on implantable electronic device leads in some patients undergoing electrophysiologic procedures.
    Methods: ICE was performed in a patient undergoing ventricular tachycardia (VT) ablation.
    Results: ICE showed extensive mobile thrombi on the implantable cardioverter defibrillator lead. Radiofrequency catheter ablation of VT from perimitral scar was safely performed via a retrograde aortic approach. After the procedure, chronic anticoagulation was initiated. CT-angiography of the chest 2 months later showed no pulmonary emboli.
    Conclusions: The significance of these thrombi, as related to chronic pulmonary embolization, warrants further study.
    MeSH term(s) Humans ; Tachycardia, Ventricular/diagnostic imaging ; Tachycardia, Ventricular/surgery ; Wind ; Heart Diseases/surgery ; Thrombosis/diagnostic imaging ; Thrombosis/etiology ; Catheter Ablation/methods ; Hair ; Treatment Outcome
    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.16079
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  4. Article ; Online: The R Wave Amplitude in Lead aVL Could Predict Successful Catheter Ablation of Ventricular Arrhythmias Originating below the His Bundle Region of the Right Ventricle.

    Nodera, Minoru / Igarashi, Miyako / Hasegawa, Kanae / Aonuma, Kazutaka / Nogami, Akihiko / Tada, Hiroshi

    International heart journal

    2023  Volume 64, Issue 4, Page(s) 614–622

    Abstract: Radiofrequency catheter ablation (RFCA) to treat ventricular arrhythmias (VAs) originating below the His bundle (HB) region of the right ventricular (RV) septum could impair the atrioventricular node conduction. This study aimed to clarify the parameters ...

    Abstract Radiofrequency catheter ablation (RFCA) to treat ventricular arrhythmias (VAs) originating below the His bundle (HB) region of the right ventricular (RV) septum could impair the atrioventricular node conduction. This study aimed to clarify the parameters of the 12-lead electrocardiography that predict successful RFCA of VAs originating from this region. This study included 20 consecutive patients (13 men; mean age, 68 ± 7 years) with monomorphic VAs in whom the earliest ventricular activation during the VA was below the HB region of the RV septum. According to the ablation results, the patients were divided into two groups: successful ablation (S-group; n = 10) and failed ablation groups (F-group; n = 10). The electrocardiographic parameters during the VAs and RFCA results were assessed. The R wave amplitudes in leads aVL (P = 0.001) and I (P = 0.010) in the S-group were both smaller than those in the F-group. In addition, the S-group had smaller negative deflection amplitudes in leads III (P = 0.002) and aVF (P = 0.003) than the F-group. According to the receiver operating characteristic curve analysis, the most useful electrocardiographic parameter for predicting successful ablation was the R wave amplitude in lead aVL (area under the curve, 0.895; P < 0.001); a cutoff value of < 1.3 mV predicted a successful RFCA with the highest accuracy (sensitivity, 90%; specificity, 80%; positive predictive value, 82%; negative predictive value, 89%). The R wave amplitude in lead aVL was the most useful parameter for predicting a successful RFCA to treat VAs originating below the HB region of the RV septum.
    MeSH term(s) Male ; Humans ; Middle Aged ; Aged ; Heart Ventricles ; Bundle of His/surgery ; Tachycardia, Ventricular/diagnosis ; Tachycardia, Ventricular/surgery ; Arrhythmias, Cardiac ; Electrocardiography/methods ; Catheter Ablation/methods ; Treatment Outcome
    Language English
    Publishing date 2023-07-14
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2187806-7
    ISSN 1349-3299 ; 1349-2365
    ISSN (online) 1349-3299
    ISSN 1349-2365
    DOI 10.1536/ihj.23-054
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  5. Article ; Online: Epicardial adipose tissue density predicts the presence of atrial fibrillation and its recurrence after catheter ablation: three-dimensional reconstructed image analysis.

    Nodera, Minoru / Ishida, Tomokazu / Hasegawa, Kanae / Kakehashi, Shota / Mukai, Moe / Aoyama, Daisetsu / Miyazaki, Shinsuke / Uzui, Hiroyasu / Tada, Hiroshi

    Heart and vessels

    2024  

    Abstract: Epicardial adipose tissue (EAT) induces inflammation in the atria and is associated with atrial fibrillation (AF). Several studies have examined the relationship between EAT volume (EAT-V) and density (EAT-D) and the presence of AF after catheter ... ...

    Abstract Epicardial adipose tissue (EAT) induces inflammation in the atria and is associated with atrial fibrillation (AF). Several studies have examined the relationship between EAT volume (EAT-V) and density (EAT-D) and the presence of AF after catheter ablation. However, conclusions have been inconsistent. This study included 43 consecutive patients who underwent catheter ablation for AF and 30 control patients. EAT-V and EAT-D around the entire heart, entire atrium, left atrium (LA), and right atrium (RA) were measured in detail using reconstructed three-dimensional (3D) EAT images from dual-source computed tomography (CT). None of the measurements of EAT-V differed significantly between patients with AF and controls or between patients with recurrent AF and those without. On the other hand, all measurements of EAT-D were higher in patients with AF than in controls (entire atrium, p < 0.001; RA, p < 0.001; LA, p = 0.002). All EAT-D measurements were associated with the presence of AF. Among patients with AF who underwent ablation, all EAT-D measurements were higher in patients with recurrent AF than in those without. The difference was significant for EATRA-D (p = 0.032). All atrial EAT-D values predicted recurrent AF (EATRA-D: hazard ratio [HR], 1.208; 95% confidence interval [95% CI], 1.053-1.387; p = 0.007; EATLA-D: HR, 1.108; 95% CI 1.001-1.225; p = 0.047; EATatrial-D: HR, 1.174; 95% CI 1.040-1.325; p = 0.010). The most sensitive cutoffs for predicting recurrent AF were highly accurate for EATRA-D (area under the curve [AUC], 0.76; p < 0.01) and EATatrial-D (AUC = 0.75, p < 0.05), while the cutoff for EATLA-D had low accuracy (AUC, 0.65; p = 0.209). For predicting the presence of AF and recurrent AF after catheter ablation, 3D analysis of atrial EAT-D, rather than EAT-V, is useful.
    Language English
    Publishing date 2024-03-18
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 89678-0
    ISSN 1615-2573 ; 0910-8327 ; 0935-736X
    ISSN (online) 1615-2573
    ISSN 0910-8327 ; 0935-736X
    DOI 10.1007/s00380-024-02384-8
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  6. Article ; Online: Correction: Gender Differences in the Inheritance Mode of RYR2 Mutations in Catecholaminergic Polymorphic Ventricular Tachycardia Patients.

    Ohno, Seiko / Hasegawa, Kanae / Horie, Minoru

    PloS one

    2021  Volume 16, Issue 2, Page(s) e0243476

    Abstract: This corrects the article DOI: 10.1371/journal.pone.0131517.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.pone.0131517.].
    Language English
    Publishing date 2021-02-19
    Publishing country United States
    Document type Published Erratum
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0243476
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  7. Article ; Online: Durability of a right superior pulmonary vein isolation after an inevitably interrupted single short freeze during cryoballoon ablation.

    Miyazaki, Shinsuke / Hasegawa, Kanae / Iesaka, Yoshito

    Journal of cardiovascular electrophysiology

    2021  Volume 32, Issue 9, Page(s) 2418–2423

    Abstract: Background: In cryoballoon ablation, applications for right superior pulmonary veins (RSPVs) inevitably need to be interrupted for some safety reasons. We retrospectively investigated the RSPV isolation durability after single interrupted short freezes.! ...

    Abstract Background: In cryoballoon ablation, applications for right superior pulmonary veins (RSPVs) inevitably need to be interrupted for some safety reasons. We retrospectively investigated the RSPV isolation durability after single interrupted short freezes.
    Methods: Data from 30 patients who underwent repeat procedures 8.2 (4.1-13.8) months after an inevitably interrupted single short freeze (<180 s) for RSPVs during the index cryoballoon procedures were analyzed. It was interrupted by active deflation due to phrenic nerve injury (PNI) (Group 1: n = 14) or passive deflation due to a balloon temperature of -60°C (Group 2: n = 16).
    Results: The freezing time was 145 (107-166) and 142 (127-160) s and nadir balloon temperature -50.7 ± 3.6 and -60°C in Groups 1 and 2, respectively. Pulmonary vein isolation was achieved after interrupted freezing in all except in one patient requiring touch-up ablation in Group 1. All PNI was asymptomatic and recovered during the follow-up. Eight/13 (61.5%) and 16/16 (100%) RSPVs were durable during the second procedure in Groups 1 and 2. In Group 1, the freezing time was significantly longer in durable than reconnected RSPVs (p = .032), and the optimal cutoff point for the freezing duration to predict the durability was 94.0 s (sensitivity 100%, specificity 60.0%). When the freezing time was ≥120 s, 80% of the RSPVs were durable. However, when the freezing time was ≤68 s, all RSPVs were reconnected.
    Conclusions: The feasibility of second cryoapplications for RSPVs should be discussed considering the freezing time of the interrupted initial applications in Group 1, however, it was not necessary in Group 2.
    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Catheter Ablation/adverse effects ; Cryosurgery/adverse effects ; Freezing ; Humans ; Pulmonary Veins/surgery ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2021-07-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.15163
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  8. Article ; Online: Cryoballoon left atrial roof ablation for persistent atrial fibrillation-Analysis with high-resolution mapping system.

    Miyazaki, Shinsuke / Hasegawa, Kanae / Mukai, Moe / Aoyama, Daisetsu / Nodera, Minoru / Uzui, Hiroyasu / Tada, Hiroshi

    Pacing and clinical electrophysiology : PACE

    2022  Volume 45, Issue 5, Page(s) 589–597

    Abstract: Background: Additional benefit of cryoballoon left atrial roof line ablation (CB-RA) beyond cryoballoon pulmonary vein isolation (CB-PVI) is suggested in patients with persistent atrial fibrillation (PsAF). We sought to investigate the feasibility of CB- ...

    Abstract Background: Additional benefit of cryoballoon left atrial roof line ablation (CB-RA) beyond cryoballoon pulmonary vein isolation (CB-PVI) is suggested in patients with persistent atrial fibrillation (PsAF). We sought to investigate the feasibility of CB-RA for PsAF and to determine the ablation area.
    Methods and results: Fifty-three PsAF patients (67[58.5-75.5] years, 36 men, 11 longstanding PsAF) underwent CB-PVI. Subsequently, 44(83.0%) out of 53 patients underwent additional CB-RA. Voltage maps were created in all patients with a high-resolution mapping system. The total number and duration of CB-RAs were 3.9 ± 0.7 and 468 ± 84 s. LA roof areas were complete low voltage areas (LVAs) /scar in 37/44(84.1%) patients ("complete roof modification"). The normal LA posterior wall (LAPW) voltage area was 6.1(4.1-8.4) cm
    Conclusions: CB-RA significantly expanded the LAPW isolation area, and a complete roof modification resulted in a high arrhythmia freedom in PsAF patients.
    MeSH term(s) Atrial Fibrillation ; Catheter Ablation/methods ; Cryosurgery/methods ; Humans ; Male ; Pulmonary Veins/surgery ; Recurrence ; Treatment Outcome
    Language English
    Publishing date 2022-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14345
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  9. Article: Importance of alpha-gal syndrome in patients undergoing catheter ablation.

    Hasegawa, Kanae / Powers, Edward M / Yoneda, Zachary T / Richardson, Travis D / Siegrist, Kara K / Stevenson, William G

    HeartRhythm case reports

    2023  Volume 9, Issue 12, Page(s) 926–928

    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2023.10.001
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  10. Article ; Online: Treatment with catheter ablation for patients with arrhythmia-induced cardiomyopathy caused by atrial fibrillation promises a good prognosis.

    Aoyama, Daisetsu / Miyazaki, Shinsuke / Amaya, Naoki / Tama, Naoto / Hasegawa, Kanae / Nomura, Ryohei / Tsuji, Toshihiko / Nakano, Akira / Uzui, Hiroyasu / Tada, Hiroshi

    Heart and vessels

    2023  Volume 39, Issue 3, Page(s) 240–251

    Abstract: Clinical outcomes after catheter ablation in patients with reduced left ventricular (LV) ejection fraction (EF) and atrial fibrillation (AF) remain unclear. This study aimed to explore the clinical outcomes of patients with arrhythmia-induced ... ...

    Abstract Clinical outcomes after catheter ablation in patients with reduced left ventricular (LV) ejection fraction (EF) and atrial fibrillation (AF) remain unclear. This study aimed to explore the clinical outcomes of patients with arrhythmia-induced cardiomyopathy (AIC) and the influence of pharmacological treatment on clinical outcomes in patients with AIC after the procedure. Ninety-six patients with AF with a reduced LVEF (LVEF < 50%, 66.7 ± 10.9 years; 72 males) underwent AF ablation. AIC was defined as patients whose LVEF recovered ≥ 50% after catheter ablation (n = 67) and patients whose LVEF remained reduced were defined as non-AIC (n = 29). During a median follow-up of 25 (13-40) months, Kaplan-Meier analysis demonstrated that patients with AIC were associated with less frequent cardiovascular death (p = 0.025) and hospitalization for worsening heart failure (p < 0.001) than those without AIC. Freedom from AF recurrence was similar between the two groups (p = 0.47). In multivariate analysis, the LV end-diastolic diameter (p = 0.0002) and the CHA
    MeSH term(s) Male ; Humans ; Atrial Fibrillation/complications ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Treatment Outcome ; Heart Failure ; Ventricular Dysfunction, Left/etiology ; Cardiomyopathies/complications ; Cardiomyopathies/diagnosis ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Stroke Volume ; Ventricular Function, Left
    Language English
    Publishing date 2023-10-23
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 89678-0
    ISSN 1615-2573 ; 0910-8327 ; 0935-736X
    ISSN (online) 1615-2573
    ISSN 0910-8327 ; 0935-736X
    DOI 10.1007/s00380-023-02329-7
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