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  1. Article ; Online: Addressing comprehensive complexities a striking familial hypercholesterolemia case study.

    Rasheed, Shazia / Kubra, Ghulam / Baqai, Lubna / Raza, Muhammad Liaquat / Hassan, Fariha / Rizvi, Syed Ghazi Abbas

    The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

    2024  Volume 76, Issue 1, Page(s) 51

    Abstract: Background: Premature aortic involvement and comprehensive management strategies in familial hypercholesterolemia familial hypercholesterolemia (FH), a rare autosomal dominant genetic disorder, poses significant challenges due to its propensity for ... ...

    Abstract Background: Premature aortic involvement and comprehensive management strategies in familial hypercholesterolemia familial hypercholesterolemia (FH), a rare autosomal dominant genetic disorder, poses significant challenges due to its propensity for elevated low-density lipoprotein cholesterol, premature coronary heart disease, and vascular atherosclerosis.
    Case presentation: Unraveling Cardiovascular Complexities: A Striking Familial Hypercholesterolemia. This case study delves into a remarkable instance of FH in a 16-year-old female who presented with chest pain and worsening dyspnea. Diagnostic evaluation revealed distinct electrocardiographic changes, elevated troponin levels, and profound dyslipidemia. Remarkable findings on transthoracic echocardiography, computed tomography angiography, and catheterization prompted multidisciplinary interventions and demonstrated remarkable enhancements in ventricular function, mitral regurgitation, and aortic stenosis.
    Conclusion: The case study underscores the urgency of comprehensive management strategies in confronting the myriad challenges of FH, emphasizing the value of early intervention, innovative therapies, and rigorous imaging modalities for unraveling the intricate cardiovascular manifestations of this condition.
    Language English
    Publishing date 2024-04-20
    Publishing country Germany
    Document type Journal Article
    ISSN 2090-911X
    ISSN (online) 2090-911X
    DOI 10.1186/s43044-024-00483-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Bacterial community characterization of Batura Glacier in the Karakoram Range of Pakistan.

    Ali, Pervaiz / Chen, Feng / Hassan, Fariha / Sosa, Ana / Khan, Samiullah / Badshah, Malik / Shah, Aamer Ali

    International microbiology : the official journal of the Spanish Society for Microbiology

    2021  Volume 24, Issue 2, Page(s) 183–196

    Abstract: High-altitude cold habitats of the Karakoram are rarely explored for their bacterial community characterization and metabolite productions. In the present study, bacterial communities in ice, water, and sediments of Batura Glacier were investigated using ...

    Abstract High-altitude cold habitats of the Karakoram are rarely explored for their bacterial community characterization and metabolite productions. In the present study, bacterial communities in ice, water, and sediments of Batura Glacier were investigated using culture-dependent and culture-independent methods. Twenty-seven cold-adapted bacterial strains (mostly psychrotrophic) were isolated using R2A, Tryptic Soy Agar (TSA), and Luria-Bertani (LB) media, at 4 °C and 15 °C. Most of the isolates exhibited growth at a wide range of temperature (4-35 °C), pH (5-12), and salinity (1-6%). Among the bacterial isolates, 52% were identified as Gram-positive and the remaining 48% represented as Gram-negative. The results of phylogenetic analysis indicated that all the culturable bacteria belonged to 3 major phylogenetic groups, i.e., Actinobacteria (48%), Bacteroidetes (26%), and Proteobacteria (22%), while Flavobacterium (26%), Arthrobacter (22%), and Pseudomonas (19%) were represented as the dominant genera. Similarly, Illumina amplicon sequencing of 16S rRNA genes after PCR amplification of DNA from the whole community revealed dominance of the same phylogenetic groups, Proteobacteria, Actinobacteria, and Bacteroidetes, while Arthrobacter, Mycoplana, Ochrobactrum, Kaistobacter, Janthinobacterium, and Flavobacterium were found as the dominant genera. Among the culturable isolates, 70% demonstrated activity for cellulases, 48% lipases, 41% proteases, 41% DNases, and only 7% for amylases. Most of the glacial isolates demonstrated antimicrobial activity against other microorganisms including the multiple-drug-resistant strains of Candida albicans, Klebsiella pneumoniae, Acinetobacter sp., and Bacillus sp. 67% of Gram-negative while 46% of Gram-positive glacial bacteria were resistant to trimethoprim/sulfamethoxazole. Resistance against methicillin and vancomycin among the Gram-positive isolates was 23% and 15%, respectively, while 11% of the Gram-negative isolates exhibited resistance against both colistin sulfate and nalidixic acid.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Bacteria/classification ; Bacteria/drug effects ; Bacteria/genetics ; Bacteria/isolation & purification ; DNA, Bacterial/genetics ; DNA, Ribosomal/genetics ; Ice Cover/microbiology ; Microbiota ; Pakistan ; Phylogeny ; RNA, Ribosomal, 16S/genetics
    Chemical Substances Anti-Bacterial Agents ; DNA, Bacterial ; DNA, Ribosomal ; RNA, Ribosomal, 16S
    Language English
    Publishing date 2021-01-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1454951-7
    ISSN 1618-1905 ; 1139-6709
    ISSN (online) 1618-1905
    ISSN 1139-6709
    DOI 10.1007/s10123-020-00153-x
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4964: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Evaluation of prescription errors and prescribing indicators in the private practices in Bahawalpur, Pakistan.

    Atif, Muhammad / Azeem, Muhammad / Rehan Sarwar, Muhammad / Malik, Iram / Ahmad, Wajiha / Hassan, Fariha / Rehman, Ayesha / Rana, Mahjabeen

    Journal of the Chinese Medical Association : JCMA

    2018  Volume 81, Issue 5, Page(s) 444–449

    Abstract: Background: Appropriate use of medicines is important to provide quality health. The aim of this study was to assess the prescribing practices and prescription errors in the private clinic practices of Bahawalpur, Pakistan.: Methods: A cross- ... ...

    Abstract Background: Appropriate use of medicines is important to provide quality health. The aim of this study was to assess the prescribing practices and prescription errors in the private clinic practices of Bahawalpur, Pakistan.
    Methods: A cross-sectional observational study was performed in March 2015 to assess the prescribing practices and prescription errors in the private clinical practices of Bahawalpur, Pakistan. We used the standard World Health Organization (WHO) methodology to achieve the study objectives. A convenience sampling technique was used to collect the prescriptions from five community pharmacies.
    Results: A total of 300 prescriptions were collected. Among the prescribing indicators, the average number of drugs per encounter was 4.5, 23.3% of drugs were prescribed by generic name, 39.6% of encounters resulted in the prescription of antibiotics, in 19% of encounters injections were prescribed and 54.5% of the drugs prescribed were from the Essential Drugs List. A total of 1218 omissions, 510 commissions and 199 drug interaction-related errors were recorded.
    Conclusion: Irrational prescribing of medicines and low compliance with the standards of prescription writing were observed in the private clinical practices of Bahawalpur.
    MeSH term(s) Cross-Sectional Studies ; Drug Interactions ; Drug Prescriptions ; Humans ; Medication Errors/prevention & control ; Pakistan ; Pharmacies ; Private Practice
    Language English
    Publishing date 2018-03-13
    Publishing country Netherlands
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 2107283-8
    ISSN 1728-7731 ; 1726-4901
    ISSN (online) 1728-7731
    ISSN 1726-4901
    DOI 10.1016/j.jcma.2017.12.002
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2699: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: Prevalence of Multi-Drug Resistant

    Ali, Sajid / Khan, Muhammad Tahir / Khan, Anwar Sheed / Mohammad, Noor / Khan, Muhammad Mumtaz / Ahmad, Sajjad / Noor, Sadiq / Jabbar, Abdul / Daire, Cantillon / Hassan, Fariha

    Polish journal of microbiology

    2020  Volume 69, Page(s) 1–5

    Abstract: Anti-tuberculosis therapy involves the combination of drugs to hamper the growth of : Anti-tuberculosis therapy involves the combination of drugs to hamper the growth ... ...

    Abstract Anti-tuberculosis therapy involves the combination of drugs to hamper the growth of
    Anti-tuberculosis therapy involves the combination of drugs to hamper the growth of
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antitubercular Agents/pharmacology ; Child ; Child, Preschool ; Drug Resistance, Multiple, Bacterial/genetics ; Endemic Diseases/statistics & numerical data ; Female ; Humans ; Infant ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Mycobacterium tuberculosis/drug effects ; Pakistan/epidemiology ; Prevalence ; Sex Factors ; Sputum/microbiology ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/epidemiology ; Young Adult
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2020-04-05
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2234080-4
    ISSN 2544-4646 ; 1733-1331
    ISSN (online) 2544-4646
    ISSN 1733-1331
    DOI 10.33073/pjm-2020-005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Effect of centrifugation on water recycling and algal growth to enable algae biodiesel production.

    Igou, Thomas / Van Ginkel, Steven W / Penalver-Argueso, Patricia / Fu, Hao / Doi, Shusuke / Narode, Asmita / Cheruvu, Sarasija / Zhang, Qian / Hassan, Fariha / Woodruff, Frazier / Chen, Yongsheng

    Water environment research : a research publication of the Water Environment Federation

    2015  Volume 86, Issue 12, Page(s) 2325–2329

    Abstract: The latest research shows that algal biofuels, at the production levels mandated in the Energy Independence and Security Act of 2007, will place significant demands on water and compete with agriculture meant for food production. Thus, there is a great ... ...

    Abstract The latest research shows that algal biofuels, at the production levels mandated in the Energy Independence and Security Act of 2007, will place significant demands on water and compete with agriculture meant for food production. Thus, there is a great need to recycle water while producing algal biofuels. This study shows that when using a synthetic medium, soluble algal products, bacteria, and other inhibitors can be removed by centrifugation and enable water recycling. Average water recovery reached 84% and water could be recycled at least 10 times without reducing algal growth.
    MeSH term(s) Biofuels/analysis ; Centrifugation ; Chlorella/growth & development ; Chlorella/metabolism ; Water Purification
    Chemical Substances Biofuels
    Language English
    Publishing date 2015-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1098976-6
    ISSN 1554-7531 ; 1061-4303 ; 1047-7624
    ISSN (online) 1554-7531
    ISSN 1061-4303 ; 1047-7624
    DOI 10.2175/106143014x14062131178871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 490: Show issues Location:
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