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  1. Book: Lecture notes on medical microbiology

    Elliott, Tom / Hastings, Mark / Desselberger, Ulrich

    (The lecture notes series)

    1997  

    Title variant Medical microbiology
    Author's details Tom Elliott ; Mark Hastings ; Ulrich Desselberger
    Series title The lecture notes series
    Keywords Microbiology ; Communicable Diseases / microbiology
    Language English
    Size VIII, 343 S. : Ill., graph. Darst.
    Edition 3. ed.
    Publisher Blackwell Science
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT007576011
    ISBN 0-632-02446-1 ; 0-632-03534-X ; 978-0-632-02446-9 ; 978-0-632-03534-2
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Psychopathy and Identification of Facial Expressions of Emotion.

    Hastings, Mark E / Tangney, June P / Stuewig, Jeff

    Personality and individual differences

    2011  Volume 44, Issue 7, Page(s) 1474–1483

    Abstract: The authors examined the association between psychopathy and identification of facial expressions of emotion. Previous research in this area is scant and has produced contradictory findings (Blair et. al., 2001, 2004; Glass & Newman, 2006; Kosson et al., ...

    Abstract The authors examined the association between psychopathy and identification of facial expressions of emotion. Previous research in this area is scant and has produced contradictory findings (Blair et. al., 2001, 2004; Glass & Newman, 2006; Kosson et al., 2002). One hundred and forty-five male jail inmates, rated using the Hare Psychopathy Checklist: Screening Version participated in a facial affect recognition task. Participants were shown faces containing one of five emotions (happiness, sadness, fear, anger, or shame) displayed at one of two different levels of intensity of expression (100% or 60%). The authors predicted that psychopathy would be associated with decreased affect recognition, particularly for sad and fearful emotional expressions, and decreased recognition of less intense displays of facial affect. Results were largely consistent with expectations in that psychopathy was negatively correlated with overall facial recognition of affect, sad facial affect, and recognition of less intense displays of affect. An unexpected negative correlation with recognition of happy facial affect was also found. These results suggest that psychopathy may be associated with a general deficit in affect recognition.
    Language English
    Publishing date 2011-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 625323-4
    ISSN 0191-8869
    ISSN 0191-8869
    DOI 10.1016/j.paid.2008.01.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Assessing Jail Inmates' Proneness to Shame and Guilt: Feeling Bad About the Behavior or the Self?

    Tangney, June P / Stuewig, Jeffrey / Mashek, Debra / Hastings, Mark

    Criminal justice and behavior

    2011  Volume 38, Issue 7, Page(s) 710–734

    Abstract: This study of 550 jail inmates (379 male and 171 female) held on felony charges examines the reliability and validity of the Test of Self Conscious Affect -Socially Deviant Version (TOSCA-SD; Hanson & Tangney, 1996) as a measure of offenders' proneness ... ...

    Abstract This study of 550 jail inmates (379 male and 171 female) held on felony charges examines the reliability and validity of the Test of Self Conscious Affect -Socially Deviant Version (TOSCA-SD; Hanson & Tangney, 1996) as a measure of offenders' proneness to shame and proneness to guilt. Discriminant validity (e.g., vis-à-vis self-esteem, negative affect, social desirability/impression management) and convergent validity (e.g., vis-à-vis correlations with empathy, externalization of blame, anger, psychological symptoms, and substance use problems) was supported, paralleling results from community samples. Further, proneness to shame and guilt were differentially related to widely used risk measures from the field of criminal justice (e.g., criminal history, psychopathy, violence risk, antisocial personality). Guilt-proneness appears to be a protective factor, whereas there was no evidence that shame-proneness serves an inhibitory function. Subsequent analyses indicate these findings generalize quite well across gender and race. Implications for intervention and sentencing practices are discussed.
    Language English
    Publishing date 2011-07-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1500128-3
    ISSN 1552-3594 ; 0093-8548
    ISSN (online) 1552-3594
    ISSN 0093-8548
    DOI 10.1177/0093854811405762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Predictive and incremental validity of the Violence Risk Appraisal Guide scores with male and female jail inmates.

    Hastings, Mark E / Krishnan, Shilpa / Tangney, June P / Stuewig, Jeffrey

    Psychological assessment

    2011  Volume 23, Issue 1, Page(s) 174–183

    Abstract: The present study examines the predictive and incremental validity of Violence Risk Appraisal Guide scores in a sample of 328 male and 145 female jail inmates held on felony charges. Significant gender differences were observed in VRAG item and total ... ...

    Abstract The present study examines the predictive and incremental validity of Violence Risk Appraisal Guide scores in a sample of 328 male and 145 female jail inmates held on felony charges. Significant gender differences were observed in VRAG item and total score means, as well as in correlations between the VRAG and concurrent measures of aggression. VRAG scores significantly predicted institutional misconduct during incarceration and recidivism in the first year postrelease for male inmates but not for female inmates. In terms of incremental validity, VRAG scores predicted institutional misconduct and recidivism beyond that accounted for by psychopathy for male inmates but not for female inmates. Implications for clinical practice and future research are discussed.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aggression/psychology ; Female ; Humans ; Male ; Middle Aged ; Personality Assessment/standards ; Personality Inventory/standards ; Predictive Value of Tests ; Prisoners/psychology ; ROC Curve ; Reproducibility of Results ; Risk Assessment ; Sex Factors ; Violence/prevention & control ; Violence/psychology ; Young Adult
    Language English
    Publishing date 2011-03-07
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1000939-5
    ISSN 1939-134X ; 1040-3590
    ISSN (online) 1939-134X
    ISSN 1040-3590
    DOI 10.1037/a0021290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Borderline Personality Disorder Among Jail Inmates: How Common and How Distinct?

    Conn, Courtney / Warden, Rebecca / Stuewig, Jeffrey / Kim, Elysha H / Harty, Laura / Hastings, Mark / Tangney, June P

    Corrections compendium

    2016  Volume 35, Issue 4, Page(s) 6–13

    Language English
    Publishing date 2016-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 0738-8144
    ISSN 0738-8144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Organ donation from children with meningitis.

    Mirza, Darius / Hastings, Mark / Reyes, Jorge / Green, Michael / Healey, Patrick J / Stock, Peter

    The Pediatric infectious disease journal

    2003  Volume 22, Issue 5, Page(s) 475

    MeSH term(s) Adolescent ; Brain Death ; Ceftriaxone/administration & dosage ; Fatal Outcome ; Female ; Follow-Up Studies ; Graft Survival ; Humans ; Liver Transplantation/methods ; Male ; Meningitis, Meningococcal/diagnosis ; Meningitis, Meningococcal/drug therapy ; Middle Aged ; Risk Assessment ; Tissue Donors ; Tissue and Organ Procurement ; United States
    Chemical Substances Ceftriaxone (75J73V1629)
    Language English
    Publishing date 2003-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/01.inf.0000066875.60699.41
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evidence of person-to-person transmission of oseltamivir-resistant pandemic influenza A(H1N1) 2009 virus in a hematology unit.

    Moore, Catherine / Galiano, Monica / Lackenby, Angie / Abdelrahman, Tamer / Barnes, Rosemary / Evans, Meirion R / Fegan, Christopher / Froude, Susannah / Hastings, Mark / Knapper, Steven / Litt, Emma / Price, Nicola / Salmon, Roland / Temple, Mark / Davies, Eleri

    The Journal of infectious diseases

    2010  Volume 203, Issue 1, Page(s) 18–24

    Abstract: We describe the first confirmed person-to-person transmission of oseltamivir-resistant pandemic influenza A(H1N1) 2009 virus that occurred in a hematology unit in the United Kingdom. Eleven cases of (H1N1) 2009 virus infection were identified, of which, ... ...

    Abstract We describe the first confirmed person-to-person transmission of oseltamivir-resistant pandemic influenza A(H1N1) 2009 virus that occurred in a hematology unit in the United Kingdom. Eleven cases of (H1N1) 2009 virus infection were identified, of which, ten were related as shown by sequence analysis of the hemagglutinin and neuraminidase genes. H275Y analysis demonstrated that 8 of 10 case patients had oseltamivir-resistant virus, with 4 of 8 case patients infected by direct transmission of resistant virus. Zanamivir should be considered as first-line therapy for influenza in patients with lymphopenic hematological conditions and uptake of influenza vaccination encouraged to further reduce the number of susceptible individuals.
    MeSH term(s) Adult ; Aged ; Amino Acid Substitution/genetics ; Antiviral Agents/pharmacology ; Cross Infection/transmission ; Cross Infection/virology ; Drug Resistance, Viral ; Hemagglutinins, Viral/genetics ; Hospitals ; Humans ; Influenza A Virus, H1N1 Subtype/drug effects ; Influenza A Virus, H1N1 Subtype/isolation & purification ; Influenza, Human/transmission ; Influenza, Human/virology ; Lymphopenia/complications ; Middle Aged ; Mutation, Missense ; Neuraminidase/genetics ; Oseltamivir/pharmacology ; RNA, Viral/genetics ; Sequence Analysis, DNA ; United Kingdom ; Viral Proteins/genetics
    Chemical Substances Antiviral Agents ; Hemagglutinins, Viral ; RNA, Viral ; Viral Proteins ; hemagglutinin fusogenic peptide, influenza virus ; Oseltamivir (20O93L6F9H) ; NA protein, influenza A virus (EC 3.2.1.18) ; Neuraminidase (EC 3.2.1.18)
    Language English
    Publishing date 2010-12-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiq007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Lecture notes on medical microbiology

    Elliott, Tom / Hastings, Mark / Desselberger, U / Gillies, R. R

    1997  

    Title variant Medical microbiology
    MeSH term(s) Microbiology ; Communicable Diseases/microbiology
    Language English
    Size viii, 343 p., [16] p. of plates :, ill.
    Edition 3rd ed. /
    Publisher Blackwell Science
    Publishing place Oxford ; Cambridge, Mass
    Document type Book
    Note Rev. ed. of: Lecture notes on medical microbiology / R.R. Gillies. 2nd ed. c1978.
    ISBN 9780632024469 ; 0632024461 ; 9780632035342 ; 063203534X
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article ; Online: Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas.

    Cullen, Michael / Steven, Neil / Billingham, Lucinda / Gaunt, Claire / Hastings, Mark / Simmonds, Peter / Stuart, Nicholas / Rea, Daniel / Bower, Mark / Fernando, Indrajit / Huddart, Robert / Gollins, Simon / Stanley, Andrew

    The New England journal of medicine

    2005  Volume 353, Issue 10, Page(s) 988–998

    Abstract: Background: The role of prophylactic antibacterial agents after chemotherapy remains controversial.: Methods: We conducted a randomized, double-blind, placebo-controlled trial in patients who were receiving cyclic chemotherapy for solid tumors or ... ...

    Abstract Background: The role of prophylactic antibacterial agents after chemotherapy remains controversial.
    Methods: We conducted a randomized, double-blind, placebo-controlled trial in patients who were receiving cyclic chemotherapy for solid tumors or lymphoma and who were at risk for temporary, severe neutropenia (fewer than 500 neutrophils per cubic millimeter). Patients were randomly assigned to receive either 500 mg of levofloxacin once daily or matching placebo for seven days during the expected neutropenic period. The primary outcome was the incidence of clinically documented febrile episodes (temperature of more than 38 degrees C) attributed to infection. Secondary outcomes included the incidence of all probable infections, severe infections, and hospitalization but did not include a systematic evaluation of antibacterial resistance.
    Results: A total of 1565 patients underwent randomization (784 to placebo and 781 to levofloxacin). The tumors included breast cancer (35.4 percent), lung cancer (22.5 percent), testicular cancer (14.4 percent), and lymphoma (12.8 percent). During the first cycle of chemotherapy, 3.5 percent of patients in the levofloxacin group had at least one febrile episode, as compared with 7.9 percent in the placebo group (P<0.001). During the entire chemotherapy course, 10.8 percent of patients in the levofloxacin group had at least one febrile episode, as compared with 15.2 percent of patients in the placebo group (P=0.01); the respective rates of probable infection were 34.2 percent and 41.5 percent (P=0.004). Hospitalization was required for the treatment of infection in 15.7 percent of patients in the levofloxacin group and 21.6 percent of patients in the placebo group (P=0.004). The respective rate of severe infection was 1.0 percent and 2.0 percent (P=0.15), with four infection-related deaths in each group. An organism was isolated in 9.2 percent of probable infections.
    Conclusions: Among patients receiving chemotherapy for solid tumors or lymphoma, the prophylactic use of levofloxacin reduces the incidence of fever, probable infection, and hospitalization.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis ; Antineoplastic Agents/adverse effects ; Bacterial Infections/etiology ; Bacterial Infections/mortality ; Bacterial Infections/prevention & control ; Double-Blind Method ; Female ; Fever/etiology ; Fever/prevention & control ; Hospitalization ; Humans ; Leukocyte Count ; Levofloxacin ; Male ; Middle Aged ; Neoplasms/complications ; Neoplasms/drug therapy ; Neutropenia/chemically induced ; Neutropenia/complications ; Ofloxacin/adverse effects ; Ofloxacin/therapeutic use ; Risk ; Systemic Inflammatory Response Syndrome/etiology
    Chemical Substances Anti-Bacterial Agents ; Antineoplastic Agents ; Levofloxacin (6GNT3Y5LMF) ; Ofloxacin (A4P49JAZ9H)
    Language English
    Publishing date 2005-09-08
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMoa050078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Piperacillin-tazobactam versus ciprofloxacin plus amoxicillin in the treatment of infective episodes after liver transplantation.

    Philpott-Howard, John / Burroughs, Andrew / Fisher, Neil / Hastings, Mark / Kibbler, Christopher / Mutimer, David / Patch, David / Rolando, Nancy / Wade, Jim / Wendon, Julia / O'Grady, John

    The Journal of antimicrobial chemotherapy

    2003  Volume 52, Issue 6, Page(s) 993–1000

    Abstract: An optimum antimicrobial regimen for bacterial infection after orthotopic liver transplantation has not been identified. In this prospective 4 year study of patients undergoing liver transplantation, patients were randomized to receive either ... ...

    Abstract An optimum antimicrobial regimen for bacterial infection after orthotopic liver transplantation has not been identified. In this prospective 4 year study of patients undergoing liver transplantation, patients were randomized to receive either piperacillin-tazobactam (112 patient episodes) or ciprofloxacin plus amoxicillin (105 patient episodes) for empirical treatment of infective episodes in the first 3 months after transplant. Metronidazole was added to the ciprofloxacin-amoxicillin regimen where anaerobic infection was suspected. Patient groups were comparable with respect to clinical, biochemical and haematological parameters. At the 72 h primary efficacy end-point, the overall response rate for the intention-to-treat group was 74/112 (66.1%) for piperacillin-tazobactam and 63/105 (60.0%) for ciprofloxacin plus amoxicillin (P=0.399); the corresponding figures for the per-protocol (PP) group were 73/82 (89.0%) (piperacillin-tazobactam) and 61/80 (76.3%) (ciprofloxacin plus amoxicillin) (P=0.038). At the end-of-study assessment, 58.9% of episodes in the piperacillin-tazobactam group had a successful clinical outcome, compared with 50.5% in the ciprofloxacin plus amoxicillin group (P=0.222); the corresponding figures for the PP group were 83.5% (piperacillin-tazobactam) and 68.8% (ciprofloxacin plus amoxicillin) (P=0.038). Staphylococci and aerobic Gram-negative bacilli were the predominant pathogens in both groups. Bacteria resistant to the study drugs were encountered, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and multiply-resistant Klebsiella spp. Empirical monotherapy with piperacillin-tazobactam is an effective treatment for infective episodes in liver transplant patients.
    MeSH term(s) Adolescent ; Adult ; Aged ; Amoxicillin/adverse effects ; Amoxicillin/therapeutic use ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Bacterial Infections/drug therapy ; Bacterial Infections/microbiology ; Ciprofloxacin/adverse effects ; Ciprofloxacin/therapeutic use ; Double-Blind Method ; Drug Therapy, Combination/adverse effects ; Drug Therapy, Combination/therapeutic use ; Enterobacteriaceae/drug effects ; Female ; Fever/etiology ; Humans ; Liver Transplantation ; Male ; Metronidazole/therapeutic use ; Middle Aged ; Penicillanic Acid/adverse effects ; Penicillanic Acid/analogs & derivatives ; Penicillanic Acid/therapeutic use ; Penicillins/adverse effects ; Penicillins/therapeutic use ; Piperacillin/adverse effects ; Piperacillin/therapeutic use ; Postoperative Complications/drug therapy ; Postoperative Complications/microbiology ; Prospective Studies ; Staphylococcus aureus/drug effects
    Chemical Substances Anti-Bacterial Agents ; Penicillins ; Metronidazole (140QMO216E) ; piperacillin, tazobactam drug combination (157044-21-8) ; Ciprofloxacin (5E8K9I0O4U) ; Amoxicillin (804826J2HU) ; Penicillanic Acid (87-53-6) ; Piperacillin (X00B0D5O0E)
    Language English
    Publishing date 2003-12
    Publishing country England
    Document type Clinical Trial ; Comparative Study ; Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkg463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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