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  1. Article ; Online: [7. Basic Theory and History of Pulse Sequences in MRI].

    Hata, Junichi

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2022  Volume 78, Issue 4, Page(s) 389–394

    MeSH term(s) Artifacts ; Magnetic Resonance Imaging
    Language Japanese
    Publishing date 2022-04-20
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.2022-2006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [16. Brain Mapping of Common Marmoset Using Ultra-high Magnetic Field MRI-from Structure to Function].

    Hata, Junichi

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2019  Volume 75, Issue 6, Page(s) 555–561

    MeSH term(s) Animals ; Brain ; Brain Mapping ; Callithrix ; Magnetic Fields ; Magnetic Resonance Imaging
    Language Japanese
    Publishing date 2019-06-20
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.2019_JSRT_75.6.555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [3. Introduction to MRI Image Analysis Using ImageJ].

    Hata, Junichi

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2019  Volume 75, Issue 1, Page(s) 89–94

    MeSH term(s) Image Processing, Computer-Assisted ; Magnetic Resonance Imaging ; Software
    Language Japanese
    Publishing date 2019-01-17
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.2019_JSRT_75.1.89
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [4. The Trueness and Precision in Relaxation-time Measurement Using Magnetic Resonance].

    Hata, Junichi

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2019  Volume 75, Issue 7, Page(s) 699–704

    MeSH term(s) Magnetic Resonance Spectroscopy
    Language Japanese
    Publishing date 2019-07-22
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.2019_JSRT_75.7.699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Structural MRI analysis of age-related changes and sex differences in marmoset brain volume.

    Sogabe, Kazumi / Hata, Junichi / Yoshimaru, Daisuke / Hagiya, Kei / Okano, Hirotaka James / Okano, Hideyuki

    Neuroscience research

    2024  

    Abstract: The field of aging biology, which aims to extend healthy lifespans and prevent age-related diseases, has turned its focus to the Callithrix jacchus (common marmoset) to understand the aging process better. This study utilized magnetic resonance imaging ( ... ...

    Abstract The field of aging biology, which aims to extend healthy lifespans and prevent age-related diseases, has turned its focus to the Callithrix jacchus (common marmoset) to understand the aging process better. This study utilized magnetic resonance imaging (MRI) to non-invasively analyze the brains of 216 marmosets, investigating age-related changes in brain structure; the relationship between body weight and brain volume; and potential differences between males and females. The key findings revealed that, similar to humans, Callithrix jacchus experiences a reduction in total intracranial volume, cortex, subcortex, thalamus, and cingulate volumes as they age, highlighting site-dependent changes in brain tissue. Notably, the study also uncovered sex differences in cerebellar volume. These insights into the structural connectivity and volumetric changes in the marmoset brain throughout aging contribute to accumulating valuable knowledge in the field, promising to inform future aging research and interventions for enhancing healthspan.
    Language English
    Publishing date 2024-04-16
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 605842-5
    ISSN 1872-8111 ; 0168-0102 ; 0921-8696
    ISSN (online) 1872-8111
    ISSN 0168-0102 ; 0921-8696
    DOI 10.1016/j.neures.2024.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1993: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Identification of the reporter gene combination that shows high contrast for cellular level MRI.

    Hayashi, Naoya / Hata, Junichi / Yoshida, Tetsu / Yoshimaru, Daisuke / Haga, Yawara / Oshiro, Hinako / Oku, Ayano / Kishi, Noriyuki / Shirakawa, Takako / Okano, Hideyuki

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0297273

    Abstract: Currently, we can label the certain cells by transducing specific genes, called reporter genes, and distinguish them from other cells. For example, fluorescent protein such as green fluorescence protein (GFP) is commonly used for cell labeling. However, ... ...

    Abstract Currently, we can label the certain cells by transducing specific genes, called reporter genes, and distinguish them from other cells. For example, fluorescent protein such as green fluorescence protein (GFP) is commonly used for cell labeling. However, fluorescent protein is difficult to observe in living animals. We can observe the reporter signals of the luciferin-luciferase system from the outside of living animals using in vivo imaging systems, although the resolution of this system is low. Therefore, in this study, we examined the reporter genes, which allowed the MRI-mediated observation of labeled cells in living animals. As a preliminary stage of animal study, we transduced some groups of plasmids that coded the protein that could take and store metal ions to the cell culture, added metal ions solutions, and measured their T1 or T2 relaxation values. Finally, we specified the best reporter gene combination for MRI, which was the combination of transferrin receptor, DMT1, and Ferritin-M6A for T1WI, and Ferritin-M6A for T2WI.
    MeSH term(s) Animals ; Genes, Reporter ; Ferritins/genetics ; Cell Line, Tumor ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Magnetic Resonance Imaging/methods ; Ions/metabolism
    Chemical Substances Ferritins (9007-73-2) ; Green Fluorescent Proteins (147336-22-9) ; Ions
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Formation Processes of a Solid Electrolyte Interphase at a Silicon/Sulfide Electrolyte Interface in a Model All-Solid-State Li-Ion Battery.

    Asano, Sho / Hata, Jun-Ichi / Watanabe, Kenta / Shimizu, Keisuke / Matsui, Naoki / Yamada, Norifumi L / Suzuki, Kota / Kanno, Ryoji / Hirayama, Masaaki

    ACS applied materials & interfaces

    2024  Volume 16, Issue 6, Page(s) 7189–7199

    Abstract: Understanding the electrochemical reactions at the interface between a Si anode and a solid sulfide electrolyte is essential in improving the cycle stabilities of Si anodes in all-solid-state batteries (ASSBs). Highly dense Si films with very low ... ...

    Abstract Understanding the electrochemical reactions at the interface between a Si anode and a solid sulfide electrolyte is essential in improving the cycle stabilities of Si anodes in all-solid-state batteries (ASSBs). Highly dense Si films with very low roughnesses of <1 nm were fabricated at room temperature via cathodic arc plasma deposition, which led to the formation of a Si/sulfide electrolyte model interface. Li (de)alloying through the model interface hardly occurred during the first cycle, whereas it proceeded stably in subsequent cycles. Hard X-ray photoelectron spectroscopy and neutron reflectometry directly revealed that the reduction or oxidation of the interfacial component or Li
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c16862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Restricted diffusion characteristics in oscillating gradient spin echo with mesoscopic phantom.

    Oshiro, Hinako / Hata, Junichi / Nakashima, Daisuke / Oshiro, Rintaro / Hayashi, Naoya / Haga, Yawara / Hagiya, Kei / Yoshimaru, Daisuke / Okano, Hideyuki

    Heliyon

    2024  Volume 10, Issue 4, Page(s) e26391

    Abstract: In diffusion magnetic resonance imaging, oscillating gradient spin echo (OGSE) has an extremely short diffusion time if motion probing gradient (MPG) is applied to the waveform. Further, it can detect microstructural specificity. OGSE changes sensitivity ...

    Abstract In diffusion magnetic resonance imaging, oscillating gradient spin echo (OGSE) has an extremely short diffusion time if motion probing gradient (MPG) is applied to the waveform. Further, it can detect microstructural specificity. OGSE changes sensitivity to spin displacement velocity based on the MPG phase. The current study aimed to investigate the restricted diffusion characteristics of each OGSE waveform using the capillary phantom with various b-values, frequencies, and MPG phases. We performed OGSE (b-value = 300, 500, 800, 1200, 1600, and 2000 s/mm
    Language English
    Publishing date 2024-02-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26391
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  9. Article ; Online: Distinct roles of amylin and oxytocin signaling in intrafamilial social behaviors at the medial preoptic area of common marmosets.

    Kurachi, Takuma / Shinozuka, Kazutaka / Yoshihara, Chihiro / Yano-Nashimoto, Saori / Murayama, Ayako Y / Hata, Junichi / Haga, Yawara / Okano, Hideyuki / Kuroda, Kumi O

    Communications biology

    2023  Volume 6, Issue 1, Page(s) 1231

    Abstract: Calcitonin receptor (Calcr) and its brain ligand amylin in the medial preoptic area (MPOA) are found to be critically involved in infant care and social contact behaviors in mice. In primates, however, the evidence is limited to an excitotoxic lesion ... ...

    Abstract Calcitonin receptor (Calcr) and its brain ligand amylin in the medial preoptic area (MPOA) are found to be critically involved in infant care and social contact behaviors in mice. In primates, however, the evidence is limited to an excitotoxic lesion study of the Calcr-expressing MPOA subregion (cMPOA) in a family-living primate species, the common marmoset. The present study utilized pharmacological manipulations of the cMPOA and shows that reversible inactivation of the cMPOA abolishes infant-care behaviors in sibling marmosets without affecting other social or non-social behaviors. Amylin-expressing neurons in the marmoset MPOA are distributed in the vicinity of oxytocin neurons in the anterior paraventricular nucleus of the hypothalamus. While amylin infusion facilitates infant carrying selectively, an oxytocin's inverse agonist, atosiban, reduces physical contact with non-infant family members without grossly affecting infant care. These data suggest that the amylin and oxytocin signaling mediate intrafamilial social interactions in a complementary manner in marmosets.
    MeSH term(s) Humans ; Mice ; Animals ; Preoptic Area ; Oxytocin/pharmacology ; Callithrix ; Islet Amyloid Polypeptide ; Drug Inverse Agonism ; Social Behavior
    Chemical Substances Oxytocin (50-56-6) ; Islet Amyloid Polypeptide
    Language English
    Publishing date 2023-12-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-023-05593-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A shift of brain network hub after spinal cord injury.

    Matsubayashi, Kohei / Shinozaki, Munehisa / Hata, Junichi / Komaki, Yuji / Nagoshi, Narihito / Tsuji, Osahiko / Fujiyoshi, Kanehiro / Nakamura, Masaya / Okano, Hideyuki

    Frontiers in molecular neuroscience

    2023  Volume 16, Page(s) 1245902

    Abstract: Background: Spinal cord injury (SCI) causes severe sequelae and significant social loss, depending on the extent of the damage. Most previous studies have focused on the pathology of the spinal cord to develop treatments for SCI. However, it is now ... ...

    Abstract Background: Spinal cord injury (SCI) causes severe sequelae and significant social loss, depending on the extent of the damage. Most previous studies have focused on the pathology of the spinal cord to develop treatments for SCI. However, it is now known that the brain, which is not directly damaged, also undergoes morphological changes after spinal cord injury, which could affect natural recovery and treatment. In recent years, magnetic resonance imaging (MRI) has been developed to analyze functional changes in the brain. Resting-state functional MRI (rsfMRI), which captures brain activity at rest, can calculate functional connections between brain areas and identify central hubs by network analysis.
    Purpose: We aim to investigate functional connectivity in the brain using rsfMRI after SCI and to determine how brain-network main hubs change over time.
    Methods: We evaluated rsfMRI in 10 mice of the contusional SCI model and calculated connectivity using graph theory. We evaluated "centrality," a representative parameter of network analysis. The subtype of centrality was degree centrality, which indicates the hub function of a single area. The five times of rsfMRI were performed in each individual mouse: before injury and at 1, 3, 7, and 14 weeks post-injury.
    Results: Before the injury, the degree centralities of the primary and secondary motor cortex were high, suggesting that these motor cortices served as main hubs for motor function. After SCI, the hub function of the motor cortices decreased by 14 weeks. In contrast, hub function in the external capsule and the putamen comparatively increased with time after injury, suggesting that the extrapyramidal/subcortical system, which runs the ventral side of the spinal cord and remains after injury in this model, becomes dominant.
    Conclusion: We demonstrated the shift of the brain network hub after SCI. The results of this study provide basic information for understanding brain network changes after SCI and would be useful for treatment selection and evaluation of its efficacy in SCI patients.
    Language English
    Publishing date 2023-10-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2452967-9
    ISSN 1662-5099
    ISSN 1662-5099
    DOI 10.3389/fnmol.2023.1245902
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