LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Hatsuzawa, Saki"
  2. AU="Huß, Kristina"
  3. AU="Yi, Lisha"
  4. AU=Moorman Jonathan P
  5. AU="Tallaksen, Helene Bandsholm Leere"
  6. AU=Kramer Barnett S
  7. AU="Wurm, Johannes"
  8. AU="Chahboune, Halima"
  9. AU="Louache, Fawzia"
  10. AU="Ghanim, Husam"
  11. AU="Cassetta, Alberto"
  12. AU="Guan, Xiao-Li"
  13. AU="de Neve-Enthoven, N G M"
  14. AU="Konjeti R. Sekhar"
  15. AU="Dufresne, Eric M"
  16. AU="Pérez-Monje, Dan A"
  17. AU="Gazzola, Stefania"
  18. AU="Gruner, William"
  19. AU="Didichenko, Svetlana A"
  20. AU="Milone F."
  21. AU="Bianski, Brandon"
  22. AU="Swan, Aili"
  23. AU="Cao, Mengli"
  24. AU="Rayya, W."
  25. AU="Bleher, Jana"
  26. AU="Fong, Fuk-Kei"
  27. AU="Bouvier, Nicolas"
  28. AU="Mims, Catherine"
  29. AU="Abbasi, Ardeshir"
  30. AU="Gailey, Samantha" AU="Gailey, Samantha"
  31. AU="Yano, Shuya"
  32. AU="Balaur, Eugeniu"
  33. AU="Ağaçfidan, Ali"
  34. AU="Perkins, James A."
  35. AU="Arkoun, Brahim"

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: Anti-Inflammatory Effects of a Novel Nuclear Factor-

    Baba, Hiroyuki / Hosoya, Tadashi / Ishida, Ryosuke / Tai, Kenpei / Hatsuzawa, Saki / Kondo, Yuma / Kusuhara, Hiroyuki / Kagechika, Hiroyuki / Yasuda, Shinsuke

    The Journal of pharmacology and experimental therapeutics

    2024  Volume 388, Issue 3, Page(s) 788–797

    Abstract: Nuclear factor- ...

    Abstract Nuclear factor-
    MeSH term(s) Mice ; Animals ; NF-kappa B/metabolism ; Arthritis, Experimental/pathology ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Inflammation/drug therapy ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Hepatitis/drug therapy ; Pyrimidines/adverse effects ; Inflammation Mediators/metabolism ; Amines/therapeutic use ; Immunoglobulin G
    Chemical Substances NF-kappa B ; Anti-Inflammatory Agents ; Pyrimidines ; Inflammation Mediators ; Amines ; Immunoglobulin G
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3106-9
    ISSN 1521-0103 ; 0022-3565
    ISSN (online) 1521-0103
    ISSN 0022-3565
    DOI 10.1124/jpet.123.001904
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uf I Zs.40: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Comprehensive exploration of chemical space using trisubstituted carboranes.

    Asawa, Yasunobu / Hatsuzawa, Saki / Yoshimori, Atsushi / Yamada, Kentaro / Katoh, Akira / Kouji, Hiroyuki / Nakamura, Hiroyuki

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 24101

    Abstract: A total of 42 trisubstituted carboranes categorised into five scaffolds were systematically designed and synthesized by exploiting the different reactivities of the twelve vertices of o-, m-, and p-carboranes to cover all directions in chemical space. ... ...

    Abstract A total of 42 trisubstituted carboranes categorised into five scaffolds were systematically designed and synthesized by exploiting the different reactivities of the twelve vertices of o-, m-, and p-carboranes to cover all directions in chemical space. Significant inhibitors of hypoxia inducible factor transcriptional activitay were mainly observed among scaffold V compounds (e.g., Vi-m, and Vo), whereas anti-rabies virus activity was observed among scaffold V (Va-h), scaffold II (IIb-g), and scaffold IV (IVb) compounds. The pharmacophore model predicted from compounds with scaffold V, which exhibited significant anti-rabies virus activity, agreed well with compounds IIb-g with scaffold II and compound IVb with scaffold IV. Normalized principal moment of inertia analysis indicated that carboranes with scaffolds I-V cover all regions in the chemical space. Furthermore, the first compounds shown to stimulate the proliferation of the rabies virus were found among scaffold V carboranes.
    Language English
    Publishing date 2021-12-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-03459-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top