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  1. Article ; Online: A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis.

    Lee, Kevin Kyungmin / Rahimi, Osman / Lee, Charlie Kyungchan / Shafi, Amaan / Hawwass, Dalia

    Medical sciences (Basel, Switzerland)

    2022  Volume 10, Issue 1

    Abstract: Background: Multiple studies have investigated the correlations of mortality, mechanical ventilation, and intensive care unit (ICU) admissions with CAC scores. This analysis overviews the prognostic capability of CAC scoring in mortality, mechanical ... ...

    Abstract Background: Multiple studies have investigated the correlations of mortality, mechanical ventilation, and intensive care unit (ICU) admissions with CAC scores. This analysis overviews the prognostic capability of CAC scoring in mortality, mechanical ventilation, and ICU admission for hospitalized COVID-19 patients. Methods: Online search was conducted on PubMed, Cochrane Library, and Scopus from inception to 22 November 2021 to identify studies involving CAC scores in relation to ICU admission, mechanical ventilation, and death rates. Results: A total of eight studies were analyzed. In the absence of CAC group compared with the presence of CAC score, there was an increase in mortality in the presence of CAC (RR 2.24, 95% CI, 1.41−3.56; p < 0.001). In the low CAC group and high CAC group, high CAC group had increase in mortality (RR 2.74; 95% CI, 1.94−3.86; p < 0.00001). There was no statistical difference in outcomes of mechanical ventilation and ICU admission between any of the groups. Conclusion: This meta-analysis strictly examined the outcomes of interest in death, mechanical ventilation, and ICU admission while comparing the CAC scores in patients with COVID-19. Given these findings, CAC scoring can aid in stratifying patients, thus allowing earlier interventions in rapidly developing illnesses.
    MeSH term(s) COVID-19 ; Calcium ; Coronary Vessels ; Humans ; Prognosis ; SARS-CoV-2
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2022-01-21
    Publishing country Switzerland
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 2754473-4
    ISSN 2076-3271 ; 2076-3271
    ISSN (online) 2076-3271
    ISSN 2076-3271
    DOI 10.3390/medsci10010005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Takotsubo Cardiomyopathy in a Vaccinated Patient with Severe COVID-19.

    Rahimi, Osman / Varada, Neilmegh / Palma, Chriselyn / Al Taweel, Omar / Lei, Kachon / Hawwass, Dalia / Ahsan, Chowdhury

    Kansas journal of medicine

    2022  Volume 15, Page(s) 255–256

    Language English
    Publishing date 2022-07-21
    Publishing country United States
    Document type Case Reports
    ISSN 1948-2035
    ISSN 1948-2035
    DOI 10.17161/kjm.vol15.16456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diversity in U.S. Cardiovascular Trainees and Leadership Where we are and What the Future Holds.

    Sossou, Christoph W / Fakhra, Sadaf / Batra, Kavita / Nouthe, Brice / Okoh, Alexis / Phillips-Wilson, Tasha / Kuria, Carolyne N / Hawwass, Dalia / Ogunniyi, Modele O / Singh, Aditi / Cohen, Marc / Dawn, Buddhadeb / Ahsan, Chowdhury H

    Current problems in cardiology

    2022  Volume 48, Issue 3, Page(s) 101518

    Abstract: Cardiovascular (CV) outcomes can be improved with commonality between provider and patient regarding gender and race/ethnicity. Slow growth in CV care provider diversity is an obstacle for women and underrepresented groups. The hope for more equitable ... ...

    Abstract Cardiovascular (CV) outcomes can be improved with commonality between provider and patient regarding gender and race/ethnicity. Slow growth in CV care provider diversity is an obstacle for women and underrepresented groups. The hope for more equitable outcomes is unlikely to be realized unless trends change in selection of CV fellows and program directors (PDs). We investigate longitudinal trends of gender and racial/ethnic composition of CV FITs. De-identified demographic data were compiled in a descriptive cross-sectional study from AAMC of internal medicine (IM) residents and CV FITs from 2011 through 2021 to evaluate gender and race/ethnicity trends among CV trainees. Trends of CV fellows who later became program directors were analyzed. In the US between 2011 and 2021, 53% of IM residents were male while 40% female (7% unreported). Among CV FITs, 78% were male and 21% female. Races/ethnicities among CV FITs consisted of 36% non-Hispanic white, 28% non-Hispanic Asian, 5% Hispanic, 4%Black, and 25% were classified within other race/ethnicity categories. The proportion who became CV program directors followed similarly: 79% of PDs were male and 21% female. Demographic profiles for CV FITs have not significantly changed over the past decade despite increased diversity among IM residents. Efforts to improve diversity of CV FITs and PDs need to be analyzed. Slow growth of diversity in CV FITs is outpaced by rising patient diversity, leading to disparities in care and poorer CV outcomes for women and underrepresented minorities. Recruiting, training, and retaining diverse CV FITs is necessary.
    MeSH term(s) Humans ; Male ; Female ; United States/epidemiology ; Cross-Sectional Studies ; Leadership ; Ethnicity ; Hispanic or Latino ; Minority Groups
    Language English
    Publishing date 2022-12-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2022.101518
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Clinical Characteristics and Implications of Bradycardia in COVID-19 Patients Treated with Remdesivir: A Single-Center Retrospective Cohort Study.

    Schreiber, Ariyon / Bauzon, Justin S / Batra, Kavita / Mohammed, Salman / Lee, Kevin / Houshmand, Nazanin / Pham, Uyen / Cosme, Celica / Inciong, Kim / Al-Taweel, Omar / Nasser, Keaton / Rana, Jibran / Sossou, Chris / Go, Ariel / Hawwass, Dalia / Diep, Jimmy / Ahsan, Chowdhury H

    Clinical drug investigation

    2022  Volume 42, Issue 9, Page(s) 763–774

    Abstract: Background and objectives: Remdesivir is an antiviral drug used to treat coronavirus disease 2019 (COVID-19) with a relatively obscure cardiac effect profile. Previous studies have reported bradycardia associated with remdesivir, but few have examined ... ...

    Abstract Background and objectives: Remdesivir is an antiviral drug used to treat coronavirus disease 2019 (COVID-19) with a relatively obscure cardiac effect profile. Previous studies have reported bradycardia associated with remdesivir, but few have examined its clinical characteristics. The objective of this study was to investigate remdesivir associated bradycardia and its associated clinical characteristics and outcomes.
    Methods: This is a single-institution retrospective study that investigated bradycardia in 600 patients who received remdesivir for treatment of COVID-19. A total of 375 patients were included in the study after screening for other known causes of bradycardia (atrioventricular [AV] nodal blockers). All patients were analyzed for episodes of bradycardia from when remdesivir was initiated up to 5 days after completion, a time frame based on the drug's putative elimination half-life. Univariate and multivariate statistical tests were conducted to analyze the data.
    Results: The mean age of the sample was 56.63 ± 13.23 years. Of patients who met inclusion criteria, 49% were found to have bradycardia within 5 days of remdesivir administration. Compared to the cohort without a documented bradycardic episode, patients with bradycardia were significantly more likely to experience inpatient mortality (22% vs 12%, p = 0.01). The patients with bradycardia were found to have marginally higher serum D-dimer levels (5.2 vs 3.4 µg/mL, p = 0.05) and were more likely to undergo endotracheal intubation (28% vs 14%, p = 0.008). Male sex, hyperlipidemia, and bradycardia within 5 days of completing remdesivir were significant predictors of inpatient mortality. No significant differences in length of stay were found.
    Conclusions: Bradycardia that occurs during or shortly after remdesivir treatment in COVID-19 patients may be associated with an increased rate of in-hospital mortality. However, COVID-19 and its cardiac complications cannot be excluded as potential contributors of bradycardia in the present study. Future studies are needed to further delineate the cardiac characteristics of COVID-19 and remdesivir.
    MeSH term(s) Adenosine Monophosphate/analogs & derivatives ; Adult ; Aged ; Alanine/adverse effects ; Alanine/analogs & derivatives ; Antiviral Agents/adverse effects ; Bradycardia/chemically induced ; Bradycardia/drug therapy ; Bradycardia/epidemiology ; COVID-19/drug therapy ; Humans ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2
    Chemical Substances Antiviral Agents ; remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Alanine (OF5P57N2ZX)
    Language English
    Publishing date 2022-08-17
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 1220136-4
    ISSN 1179-1918 ; 0114-2402 ; 1173-2563
    ISSN (online) 1179-1918
    ISSN 0114-2402 ; 1173-2563
    DOI 10.1007/s40261-022-01187-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cardiac Catheterization Laboratory Volume Changes During COVID-19-Findings from a Cardiovascular Fellows Consortium.

    Kadavath, Sabeeda / Mohan, Jay / Ashraf, Said / Kassier, Adnan / Hawwass, Dalia / Madan, Nidhi / Salehi, Negar / Bernardo, Marie / Mawri, Sagger / Rehman, Karim Abdur / Ya'qoub, Lina / Strobel, Aaron / Dixon, Simon R / Siraj, Aisha / Messenger, John / Spears, James R / Lopez-Candales, Angel / Madder, Ryan / Bailey, Steven R /
    Alaswad, Khaldoon / Kim, Michael C / Safian, Robert D / Alraies, M Chadi

    The American journal of cardiology

    2020  Volume 130, Page(s) 168–169

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiac Catheterization/trends ; Coronavirus Infections/epidemiology ; Data Collection ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Social Media
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country United States
    Document type Letter ; Multicenter Study
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2020.06.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cardiac Catheterization Laboratory Volume Changes During COVID-19 – Findings from a Cardiovascular Fellows Consortium

    Kadavath, Sabeeda / Mohan, Jay / Ashraf, Said / Kassier, Adnan / Hawwass, Dalia / Madan, Nidhi / Salehi, Negar / Bernardo, Marie / Mawri, Sagger / Rehman, Karim Abdur / Ya'qoub, Lina / Strobel, Aaron / Dixon, Simon R / Siraj, Aisha / Messenger, John / Spears, James R / Lopez-Candales, Angel / Madder, Ryan / Bailey, Steven R /
    Alaswad, Khaldoon / Kim, Michael C / Safian, Robert D / Alraies, M Chadi

    Am J Cardiol

    Keywords covid19
    Publisher Elsevier; PMC; WHO
    Document type Article ; Online
    Note WHO #Covidence: #593706
    DOI 10.1016/j.amjcard.2020.06.009
    Database COVID19

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  7. Article: Cardiac Catheterization Laboratory Volume Changes During COVID-19-Findings from a Cardiovascular Fellows Consortium

    Kadavath, Sabeeda / Mohan, Jay / Ashraf, Said / Kassier, Adnan / Hawwass, Dalia / Madan, Nidhi / Salehi, Negar / Bernardo, Marie / Mawri, Sagger / Rehman, Karim Abdur / Ya039, / qoub, Lina / Strobel, Aaron / Dixon, Simon R / Siraj, Aisha / Messenger, John / Spears, James R / Lopez-Candales, Angel / Madder, Ryan /
    Bailey, Steven R / Alaswad, Khaldoon / Kim, Michael C / Safian, Robert D / Alraies, M Chadi

    Am J Cardiol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #593706
    Database COVID19

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  8. Book ; Online: Cardiac Catheterization Laboratory Volume Changes During COVID-19-Findings from a Cardiovascular Fellows Consortium

    Kadavath, Sabeeda / Mohan, Jay / Ashraf, Said / Kassier, Adnan / Hawwass, Dalia / Madan, Nidhi / Salehi, Negar / Bernardo, Marie / Mawri, Sagger / Rehman, Karim Abdur / Ya'qoub, Lina / Strobel, Aaron / Dixon, Simon R / Siraj, Aisha / Messenger, John / Spears, James R / Lopez-Candales, Angel / Madder, Ryan / Bailey, Steven R /
    Alaswad, Khaldoon / Kim, Michael C / Safian, Robert D / Alraies, M Chadi

    Cardiology Articles

    2020  

    Keywords covid19
    Publishing date 2020-09-01T07:00:00Z
    Publisher Henry Ford Health System Scholarly Commons
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Cardiac Catheterization Laboratory Volume Changes During COVID-19—Findings from a Cardiovascular Fellows Consortium

    Kadavath, Sabeeda / Mohan, Jay / Ashraf, Said / Kassier, Adnan / Hawwass, Dalia / Madan, Nidhi / Salehi, Negar / Bernardo, Marie / Mawri, Sagger / Rehman, Karim Abdur / Ya'qoub, Lina / Strobel, Aaron / Dixon, Simon R. / Siraj, Aisha / Messenger, John / Spears, James R. / Lopez-Candales, Angel / Madder, Ryan / Bailey, Steven R. /
    Alaswad, Khaldoon / Kim, Michael C. / Safian, Robert D. / Alraies, M. Chadi

    The American Journal of Cardiology

    2020  Volume 130, Page(s) 168–169

    Keywords Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2020.06.009
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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