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  1. Book ; Online: Organizational Design for Marketing Futures

    Hayhurst, Roy / Wills, Gordon

    (Routledge Library Editions: Management Ser)

    2018  

    Abstract: Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- CONTENTS -- INTRODUCTION AND PURPOSE -- PART A: MARKETING'S FUTURE TASKS-SOME SCENARIOS -- A.1 The Corporate Planning Backlash -- A.2 Problem Orientations -- A.3 Social and Political ... ...

    Series title Routledge Library Editions: Management Ser
    Abstract Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- CONTENTS -- INTRODUCTION AND PURPOSE -- PART A: MARKETING'S FUTURE TASKS-SOME SCENARIOS -- A.1 The Corporate Planning Backlash -- A.2 Problem Orientations -- A.3 Social and Political Momentum -- A.4 The Customer Backlash -- A.5 Fashions and Fads -- PART B: HISTORICAL DEVELOPMENT OF MARKETING ORGANIZATIONS -- B.1 Theory and Practice in Organization Structures -- B.2 The Evolution of Marketing Structures -- B.3 Structural Alternatives -- (a) Function Oriented -- (b) Product Oriented -- (c) Regionally Oriented -- (d) Customer-Type Orientation -- (e) Divisionalized Marketing Structures -- B.4 The Organization of Marketing Subsystems -- (a) Sales Force Organization -- (b) Marketing Research Departments -- (c) Product Manager or Market Manager? -- B.5 Some Emergent Principles -- (a) Analysis of Company Needs -- (b) Analysis of Human Needs -- (c) Structure from the Top -- (d) Proper Balance of Talent -- (e) Staffing with the Right People -- (f) Design of Adequate Controls -- (g) Built-in Co-ordination -- (h) Evolution not Revolution -- B.6 References cited in Part B -- PART C: BRITISH ORGANIZATIONAL STATUS QUO -- C.1 Introduction -- C.2 The Chief Marketing Executive and his Responsibilities -- C.3 The Marketing Department -- C.4 External Agencies -- C.5 Advertising and Promotion -- C.6 Pricing -- C.7 Distribution Channels -- C.8 Sales Forecasting -- C.9 Written Down Marketing Plans -- C.10 Organizing for Marketing Research -- (a) The Development of Marketing Research in the United Kingdom -- (b) The Current Status of Marketing Research -- (c) Designation of Marketing Research Executives -- (d) Responsibility for Marketing Research Executives -- (e) Expenditure on Marketing Research -- (f) Profile of Marketing Research Activities -- C.11 Marketing Attitudes and Definitions

    PART D: ORGANIZATIONAL TRANSFER - ORGANIZATIONAL DEVELOPMENT -- D.1 The Routinization of Operational Marketing Activities -- D.2 The Fusion of Marketing Development and Technical Research and Development -- D.3 The Customer Service Function -- D.4 Marketing Intelligence Systems -- D.5 Total Distribution Approaches -- D.6 The International Dimension -- D.7 Ethics and Aesthetics -- D.8 Educational Development and Training -- D.9 The Present/Future Dichotomy in Organizational Design -- APPENDIX 1 RESEARCH METHODOLOGY EMPLOYED IN SURVEY OF COMPANIES -- APPENDIX 2 SURVEY QUESTIONNAIRES ON THE MARKETING ORGANIZATIONAL STATUS QUO -- APPENDIX 3 SELECTION OF DEFINITIONS OF MARKETING BY CHIEF MARKETING EXECUTIVES -- INDEX
    Language English
    Size 1 Online-Ressource (218 pages)
    Document type Book ; Online
    ISBN 9780815370079 ; 9781351250870 ; 9780815370079 ; 0815370075 ; 1351250876 ; 0815370075
    Database ECONomics Information System

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  2. Article: Norway looks to biotech as the oil starts to run out.

    Hayhurst, Richard

    Drug discovery today

    2005  Volume 10, Issue 6, Page(s) 387–390

    MeSH term(s) Biotechnology/economics ; Biotechnology/organization & administration ; Biotechnology/trends ; Commerce/trends ; Humans ; Marine Biology/trends ; Norway ; Research Support as Topic/trends
    Language English
    Publishing date 2005-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1324988-5
    ISSN 1878-5832 ; 1359-6446
    ISSN (online) 1878-5832
    ISSN 1359-6446
    DOI 10.1016/S1359-6446(05)03378-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: EuroGentest standing up to scrutiny--first year demonstrates good progress harmonizing community approaches.

    Hayhurst, Richard / Cassiman, Jean-Jacques

    Journal of applied genetics

    2006  Volume 47, Issue 1, Page(s) 5–7

    MeSH term(s) European Union ; Genetic Services/organization & administration ; Genetic Services/standards ; Genetic Testing/organization & administration ; Genetic Testing/standards ; Humans ; International Cooperation
    Language English
    Publishing date 2006
    Publishing country England
    Document type Editorial
    ZDB-ID 1235302-4
    ISSN 2190-3883 ; 1234-1983
    ISSN (online) 2190-3883
    ISSN 1234-1983
    DOI 10.1007/BF03194592
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Data Resource Profile: MedicineInsight, an Australian national primary health care database.

    Busingye, Doreen / Gianacas, Christopher / Pollack, Allan / Chidwick, Kendal / Merrifield, Alistair / Norman, Sarah / Mullin, Bernie / Hayhurst, Rachel / Blogg, Suzanne / Havard, Alys / Stocks, Nigel

    International journal of epidemiology

    2019  Volume 48, Issue 6, Page(s) 1741–1741h

    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Australia ; Child ; Child, Preschool ; Data Accuracy ; Databases as Topic ; Databases, Factual ; Electronic Health Records ; Female ; General Practice ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Primary Health Care ; Young Adult
    Language English
    Publishing date 2019-07-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187909-1
    ISSN 1464-3685 ; 0300-5771
    ISSN (online) 1464-3685
    ISSN 0300-5771
    DOI 10.1093/ije/dyz147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Medical response to a radiologic/nuclear event: integrated plan from the Office of the Assistant Secretary for Preparedness and Response, Department of Health and Human Services.

    Coleman, C Norman / Hrdina, Chad / Bader, Judith L / Norwood, Ann / Hayhurst, Robert / Forsha, Joseph / Yeskey, Kevin / Knebel, Ann

    Annals of emergency medicine

    2009  Volume 53, Issue 2, Page(s) 213–222

    Abstract: The end of the Cold War led to a reduced concern for a major nuclear event. However, the current threats from terrorism make a radiologic (dispersal or use of radioactive material) or nuclear (improvised nuclear device) event a possibility. The specter ... ...

    Abstract The end of the Cold War led to a reduced concern for a major nuclear event. However, the current threats from terrorism make a radiologic (dispersal or use of radioactive material) or nuclear (improvised nuclear device) event a possibility. The specter and enormousness of the catastrophe resulting from a state-sponsored nuclear attack and a sense of nihilism about the effectiveness of a response were such that there had been limited civilian medical response planning. Although the consequences of a radiologic dispersal device are substantial, and the detonation of a modest-sized (10 kiloton) improvised nuclear device is catastrophic, it is both possible and imperative that a medical response be planned. To meet this need, the Office of the Assistant Secretary for Preparedness and Response in the Department of Health and Human Services, in collaboration within government and with nongovernment partners, has developed a scientifically based comprehensive planning framework and Web-based "just-in-time" medical response information called Radiation Event Medical Management (available at http://www.remm.nlm.gov). The response plan includes (1) underpinnings from basic radiation biology, (2) tailored medical responses, (3) delivery of medical countermeasures for postevent mitigation and treatment, (4) referral to expert centers for acute treatment, and (5) long-term follow-up. Although continuing to evolve and increase in scope and capacity, current response planning is sufficiently mature that planners and responders should be aware of the basic premises, tools, and resources available. An effective response will require coordination, communication, and cooperation at an unprecedented level. The logic behind and components of this response are presented to allow for active collaboration among emergency planners and responders and federal, state, local, and tribal governments.
    MeSH term(s) Acute Radiation Syndrome ; Algorithms ; Civil Defense/organization & administration ; Disaster Planning/organization & administration ; Disasters ; Government Agencies ; Humans ; Mass Casualty Incidents ; Nuclear Warfare ; Radioactive Hazard Release ; Terrorism ; Transportation ; Triage ; United States ; United States Dept. of Health and Human Services
    Language English
    Publishing date 2009-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603080-4
    ISSN 1097-6760 ; 0196-0644
    ISSN (online) 1097-6760
    ISSN 0196-0644
    DOI 10.1016/j.annemergmed.2007.12.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Treatment of Yaws.

    Hayhurst, R J

    Canadian Medical Association journal

    1964  Volume 90, Issue 8, Page(s) 555

    Language English
    Publishing date 1964-02-22
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Time-dependent actions of aldosterone and amiloride on Na+-K+-ATPase of cortical collecting duct.

    Hayhurst, R A / O'Neil, R G

    The American journal of physiology

    1988  Volume 254, Issue 5 Pt 2, Page(s) F689–96

    Abstract: The actions of aldosterone on Vmax Na+-K+-ATPase activity and length of latent period were assessed for the rabbit cortical collecting duct (CCD). Initially, animals were moderately aldosterone depleted and then treated with a constant infusion of ... ...

    Abstract The actions of aldosterone on Vmax Na+-K+-ATPase activity and length of latent period were assessed for the rabbit cortical collecting duct (CCD). Initially, animals were moderately aldosterone depleted and then treated with a constant infusion of physiological doses of aldosterone. Aldosterone administration had no influence after 3 h but caused a detectable increase with 6 (borderline significance) or more hours. An apparent plateau was reached between 24 and 48 h at twice the initial activity. This aldosterone-induced stimulation could be abolished by simultaneous treatment of the animals with amiloride, demonstrating a Na+-dependent modulation of the Vmax Na+-K+-ATPase activity. The aldosterone-stimulated enzyme had kinetic properties similar to those reported by others, but the latent period for aldosterone action on the Vmax Na+-K+-ATPase activity averaged near 6 h in the present study, as opposed to the highly variable period (from 1 h to several days) seen by others. This latent period variability was shown to be directly related to the initial Vmax Na+-K+-ATPase activity in the CCD and could be likened to an "end product dependent" latent period, i.e., the lower the initial end product (Vmax Na+-K+-ATPase activity) the shorter the latent period. Hence aldosterone's actions on the Na+-K+-ATPase of the CCD would be consistent with a single mechanism of action, i.e., increased synthesis, but with a variable modulation of this synthesis, which is dependent on the initial Vmax Na+-K+-ATPase activity of the CCD cells and/or the initial aldosterone status of the animal.
    MeSH term(s) Aldosterone/pharmacology ; Amiloride/pharmacology ; Animals ; Female ; Kidney Tubules/enzymology ; Kidney Tubules, Collecting/enzymology ; Kinetics ; Rabbits ; Sodium-Potassium-Exchanging ATPase/metabolism ; Time Factors
    Chemical Substances Aldosterone (4964P6T9RB) ; Amiloride (7DZO8EB0Z3) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9)
    Language English
    Publishing date 1988-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2948-8
    ISSN 0002-9513
    ISSN 0002-9513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Functional differentiation of cell types of cortical collecting duct.

    O'Neil, R G / Hayhurst, R A

    The American journal of physiology

    1985  Volume 248, Issue 3 Pt 2, Page(s) F449–53

    Abstract: Interference-contrast and fluorescent microscopy were used to differentiate between the two cell types--principal cells (PC) and intercalated cells (IC)--of the isolated perfused cortical collecting duct of the rabbit. Using Hoffman Modulation Contrast ... ...

    Abstract Interference-contrast and fluorescent microscopy were used to differentiate between the two cell types--principal cells (PC) and intercalated cells (IC)--of the isolated perfused cortical collecting duct of the rabbit. Using Hoffman Modulation Contrast optics, two types of cell outlines could be identified: "hexagonal" and "circular" profiles. To characterize the cell types further, the binding of fluorescein-labeled peanut lectin, which has been shown to be specific for the luminal cell membrane of the IC, was monitored with epifluorescent techniques. The lectin was observed to bind to the circular cell type only, confirming it as the IC. With use of the fluorescent nuclear probe acridine orange to quantitate the total number of cells per millimeter of tubule length, the fraction of ICs (lectin-binding cells) was estimated to average 29%, and the fraction of PCs (non-lectin-binding cells) to average 71% of all cells. The studies were extended to functionally separate between the two cell types by monitoring cell swelling when a lumen-to-bath current pulse was passed. Current-induced swelling was observed only in the PC and could be inhibited by the luminal addition of both the Na+ channel blocker amiloride, and the K+ channel blocker barium, thereby implicating the PC in the process of Na+ absorption and K+ secretion in this tissue. It is concluded that optical techniques can be applied to the cortical collecting duct perfused in vitro to differentiate between and study functional properties of the cell types.
    MeSH term(s) Acridine Orange ; Amiloride/pharmacology ; Animals ; Arachis ; Barium/pharmacology ; Binding Sites ; Female ; Ion Channels/drug effects ; Ion Channels/metabolism ; Kidney Tubules/cytology ; Kidney Tubules, Collecting/cytology ; Kidney Tubules, Collecting/metabolism ; Lectins/metabolism ; Microscopy, Fluorescence ; Microscopy, Interference ; Peanut Agglutinin ; Plant Lectins ; Potassium/metabolism ; Rabbits ; Sodium/metabolism
    Chemical Substances Ion Channels ; Lectins ; Peanut Agglutinin ; Plant Lectins ; Barium (24GP945V5T) ; Amiloride (7DZO8EB0Z3) ; Sodium (9NEZ333N27) ; Acridine Orange (F30N4O6XVV) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 1985-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2948-8
    ISSN 0002-9513
    ISSN 0002-9513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Sodium-dependent modulation of the renal Na-K-ATPase: influence of mineralocorticoids on the cortical collecting duct.

    O'Neil, R G / Hayhurst, R A

    The Journal of membrane biology

    1985  Volume 85, Issue 2, Page(s) 169–179

    Abstract: Mineralocorticoids play a major role in the regulation of sodium transport in a variety of tissues, including the cortical collecting duct (CCD) of the mammalian nephron. To assess, in part, the underlying mechanism(s) of this control, the present ... ...

    Abstract Mineralocorticoids play a major role in the regulation of sodium transport in a variety of tissues, including the cortical collecting duct (CCD) of the mammalian nephron. To assess, in part, the underlying mechanism(s) of this control, the present studies were designed to evaluate, first, the influence of mineralocorticoids on the Na-K-ATPase activity in the rabbit CCD and, secondly, a possible role of sodium entry into the cell at the luminal border on the regulation of the Na-K-ATPase. In the first series of studies, rabbits were maintained on a low sodium diet which raised serum aldosterone levels from 16 to 70 ng/dl after 3-4 days, with further elevations being expressed with treatment for two weeks or more. In CCDs isolated from these animals, the Na-K-ATPase increased from 13 to 40 pmol ADP min-1 mm-1 after 3-4 days on the low sodium regimen, but then declined, returning to control values after approximately 2 weeks. This decline in activity was preceded by a decrease in the Na+ concentration of the urine to low levels and hence, likely coincided with a decreased delivery of sodium to, and sodium entry into the cells of, the CCD. If dietary manipulations were used to maintain a high delivery of sodium to the CCD in the animal, elevation of plasma mineralocorticoid levels by treatment with deoxycorticosterone acetate (DOCA) caused a similar elevation in the Na-K-ATPase activity after 3-4 days, which did not decline with continued treatment for up to 2 weeks. Furthermore, it was observed that mineralocorticoids only exerted their effect on the Na-K-ATPase after a latent period of 1 day, well after sodium excretion had fallen, indicating that sodium entry into the CCD cells was already stimulated. If animals were simultaneously treated with DOCA and the sodium channel blocker amiloride for 3-4 days, the effects on the Na-K-ATPase were markedly reduced, whereas amiloride treatment alone had no effect on the enzyme activity. Since others have shown that mineralocorticoids induce synthesis of the Na-K-ATPase subunits in toad bladder cells in an amiloride-insensitive manner, sodium must be exerting its effect on a process after translation. It is concluded that the initial effect of mineralocorticoids in the CCD is on sodium entry with a delayed induction of the Na-K-ATPase, which is regulated by Na-dependent modulation of a posttranslational process.
    MeSH term(s) Aldosterone/physiology ; Animals ; Desoxycorticosterone/pharmacology ; Dexamethasone/pharmacology ; Diet ; Female ; Kidney Cortex/enzymology ; Kidney Tubules/enzymology ; Nephrons/enzymology ; Potassium/metabolism ; Potassium/pharmacology ; Rabbits ; Sodium/metabolism ; Sodium/pharmacology ; Sodium-Potassium-Exchanging ATPase/metabolism
    Chemical Substances Desoxycorticosterone (40GP35YQ49) ; Aldosterone (4964P6T9RB) ; Dexamethasone (7S5I7G3JQL) ; Sodium (9NEZ333N27) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 1985
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3082-x
    ISSN 1432-1424 ; 0022-2631
    ISSN (online) 1432-1424
    ISSN 0022-2631
    DOI 10.1007/bf01871269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Organizational design for marketing futures

    Hayhurst, Roy / Wills, Gordon

    [by] Roy Hayhurst and Gordon Wills, in association with James Mann, Peter Cooke and Saddik Saddik

    (Studies in management, no. 10)

    1972  

    Series title Studies in management, no. 10
    Keywords Marketing.
    Language English
    Size 3-217 p. illus., forms.
    Publisher Allen and Unwin
    Publishing place London
    Document type Book
    Note Includes bibliographical references.
    Database NAL-Catalogue (AGRICOLA)

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