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  1. Article ; Online: C

    Gakhar, Teena / Hazra, Arnab

    Nanotechnology

    2021  Volume 32, Issue 50

    Abstract: The current study concerns development of fullerene- ... ...

    Abstract The current study concerns development of fullerene-C
    Language English
    Publishing date 2021-09-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ac23f9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Electroless deposition of Pd/Pt nanoparticles on electrochemically grown TiO

    Bindra, Prateek / Hazra, Arnab

    The Analyst

    2021  Volume 146, Issue 6, Page(s) 1880–1891

    Abstract: This work presents a comparative sensing study of three sensors based on pristine ... ...

    Abstract This work presents a comparative sensing study of three sensors based on pristine TiO
    Language English
    Publishing date 2021-01-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d0an01757d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2423: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Oxygen vacancy modulation of titania nanotubes by cathodic polarization and chemical reduction routes for efficient detection of volatile organic compounds.

    Gakhar, Teena / Hazra, Arnab

    Nanoscale

    2020  Volume 12, Issue 16, Page(s) 9082–9093

    Abstract: In this work, we have synthesized a highly ordered ... ...

    Abstract In this work, we have synthesized a highly ordered TiO
    Language English
    Publishing date 2020-04-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/c9nr10795a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Nanostructural evolution of hydrothermally grown SrTiO

    Bhardwaj, Radha / Jena, Sushri Soumya / Srikar, Valiveru Sai / Ghosh, Sarbani / Hazra, Arnab

    Nanotechnology

    2023  Volume 34, Issue 40

    Abstract: A group of ... ...

    Abstract A group of SrTiO
    Language English
    Publishing date 2023-07-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ace44d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Resolving the polycistronic aftermath: Essential role of topoisomerase IA in preventing R-loops in Leishmania.

    Das, Payel / Hazra, Arnab / Saha, Saradindu / Roy, Sadhana / Mukherjee, Mandrita / Hazra, Saugata / Majumdar, Hemanta K / BoseDasgupta, Somdeb

    The Journal of biological chemistry

    2024  Volume 300, Issue 4, Page(s) 107162

    Abstract: Kinetoplastid parasites are "living bridges" in the evolution from prokaryotes to higher eukaryotes. The near-intronless genome of the kinetoplastid Leishmania exhibits polycistronic transcription which can facilitate R-loop formation. Therefore, to ... ...

    Abstract Kinetoplastid parasites are "living bridges" in the evolution from prokaryotes to higher eukaryotes. The near-intronless genome of the kinetoplastid Leishmania exhibits polycistronic transcription which can facilitate R-loop formation. Therefore, to prevent such DNA-RNA hybrids, Leishmania has retained prokaryotic-like DNA Topoisomerase IA (LdTOPIA) in the course of evolution. LdTOPIA is an essential enzyme that is expressed ubiquitously and is adapted for the compartmentalized eukaryotic form in harboring functional bipartite nuclear localization signals. Although exhibiting greater homology to mycobacterial TOPIA, LdTOPIA could functionally complement the growth lethality of Escherichia coli TOPIA null GyrB ts strain at non-permissive temperatures. Purified LdTOPIA exhibits Mg
    MeSH term(s) DNA Topoisomerases, Type I/metabolism ; DNA Topoisomerases, Type I/genetics ; R-Loop Structures ; Protozoan Proteins/metabolism ; Protozoan Proteins/genetics ; Protozoan Proteins/antagonists & inhibitors ; Protozoan Proteins/chemistry ; Leishmania/enzymology ; Leishmania/genetics ; Animals ; Escherichia coli/genetics ; Escherichia coli/metabolism
    Chemical Substances DNA Topoisomerases, Type I (EC 5.99.1.2) ; Protozoan Proteins
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2024.107162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.108: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: A Bumpy Ride of Mycobacterial Phagosome Maturation: Roleplay of Coronin1 Through Cofilin1 and cAMP.

    Saha, Saradindu / Hazra, Arnab / Ghatak, Debika / Singh, Ajay Vir / Roy, Sadhana / BoseDasgupta, Somdeb

    Frontiers in immunology

    2021  Volume 12, Page(s) 687044

    Abstract: Phagosome-lysosome fusion in innate immune cells like macrophages and neutrophils marshal an essential role in eliminating intracellular microorganisms. In microbe-challenged macrophages, phagosome-lysosome fusion occurs 4 to 6 h after the phagocytic ... ...

    Abstract Phagosome-lysosome fusion in innate immune cells like macrophages and neutrophils marshal an essential role in eliminating intracellular microorganisms. In microbe-challenged macrophages, phagosome-lysosome fusion occurs 4 to 6 h after the phagocytic uptake of the microbe. However, live pathogenic mycobacteria hinder the transfer of phagosomes to lysosomes, up to 20 h post-phagocytic uptake. This period is required to evade pro-inflammatory response and upregulate the acid-stress tolerant proteins. The exact sequence of events through which mycobacteria retards phagolysosome formation remains an enigma. The macrophage coat protein Coronin1(Cor1) is recruited and retained by mycobacteria on the phagosome membrane to retard its maturation by hindering the access of phagosome maturation factors. Mycobacteria-infected macrophages exhibit an increased cAMP level, and based on receptor stimulus, Cor1 expressing cells show a higher level of cAMP than non-Cor1 expressing cells. Here we have shown that infection of bone marrow-derived macrophages with H37Rv causes a Cor1 dependent rise of intracellular cAMP levels at the vicinity of the phagosomes. This increased cAMP fuels cytoskeletal protein Cofilin1 to depolymerize F-actin around the mycobacteria-containing phagosome. Owing to reduced F-actin levels, the movement of the phagosome toward the lysosomes is hindered, thus contributing to the retarded phagosome maturation process. Additionally, Cor1 mediated upregulation of Cofilin1 also contributes to the prevention of phagosomal acidification, which further aids in the retardation of phagosome maturation. Overall, our study provides first-hand information on Cor1 mediated retardation of phagosome maturation, which can be utilized in developing novel peptidomimetics as part of host-directed therapeutics against tuberculosis.
    MeSH term(s) Animals ; Cell Line ; Cofilin 1/metabolism ; Cyclic AMP/metabolism ; Host-Pathogen Interactions ; Hydrogen-Ion Concentration ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/microbiology ; Mice ; Microfilament Proteins/genetics ; Microfilament Proteins/metabolism ; Mycobacterium Infections, Nontuberculous/immunology ; Mycobacterium Infections, Nontuberculous/metabolism ; Mycobacterium Infections, Nontuberculous/microbiology ; Mycobacterium bovis/immunology ; Mycobacterium bovis/pathogenicity ; Mycobacterium smegmatis/immunology ; Mycobacterium smegmatis/pathogenicity ; Mycobacterium tuberculosis/immunology ; Mycobacterium tuberculosis/pathogenicity ; Phagosomes/immunology ; Phagosomes/metabolism ; Phagosomes/microbiology ; Second Messenger Systems ; Tuberculosis/immunology ; Tuberculosis/metabolism ; Tuberculosis/microbiology
    Chemical Substances Cfl1 protein, mouse ; Cofilin 1 ; Microfilament Proteins ; coronin proteins (145420-64-0) ; Cyclic AMP (E0399OZS9N)
    Language English
    Publishing date 2021-09-23
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.687044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Multiple nano-filaments based efficient resistive switching in TiO

    Hazra, Arnab / Tripathi, Ashutosh / Jan, Atif / Kundu, Souvik / Boppidi, Pavan Kumar Reddy

    Nanotechnology

    2020  Volume 32, Issue 11, Page(s) 115201

    Abstract: In this paper, the impact of thermally induced self-doping and phase transformation in ... ...

    Abstract In this paper, the impact of thermally induced self-doping and phase transformation in TiO
    Language English
    Publishing date 2020-11-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/abd05c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Localized thermal spike driven morphology and electronic structure transformation in swift heavy ion irradiated TiO

    Dey, Sutapa / Chakravorty, Anusmita / Mishra, Shashi Bhusan / Khatun, Nasima / Hazra, Arnab / Nanda, Birabar Ranjit Kumar / Sudakar, Chandran / Kabiraj, Debdulal / Roy, Somnath C

    Nanoscale advances

    2021  Volume 4, Issue 1, Page(s) 241–249

    Abstract: Irradiation of materials by high energy (∼MeV) ions causes intense electronic excitations through inelastic transfer of energy that significantly modifies physicochemical properties. We report the effect of 100 MeV Ag ion irradiation and resultant ... ...

    Abstract Irradiation of materials by high energy (∼MeV) ions causes intense electronic excitations through inelastic transfer of energy that significantly modifies physicochemical properties. We report the effect of 100 MeV Ag ion irradiation and resultant localized (∼few nm) thermal spike on vertically oriented TiO
    Language English
    Publishing date 2021-11-15
    Publishing country England
    Document type Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d1na00666e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: A multivariate spatial skew-t process for joint modeling of extreme precipitation indexes

    Hazra, Arnab / Reich, Brian J. / Staicu, Ana-Maria

    2018  

    Abstract: To study trends in extreme precipitation across US over the years 1951-2017, we consider 10 climate indexes that represent extreme precipitation, such as annual maximum of daily precipitation, annual maximum of consecutive 5-day average precipitation, ... ...

    Abstract To study trends in extreme precipitation across US over the years 1951-2017, we consider 10 climate indexes that represent extreme precipitation, such as annual maximum of daily precipitation, annual maximum of consecutive 5-day average precipitation, which exhibit spatial correlation as well as mutual dependence. We consider the gridded data, produced by the CLIMDEX project (http://www.climdex.org/gewocs.html), constructed using daily precipitation data. In this paper, we propose a multivariate spatial skew-t process for joint modeling of extreme precipitation indexes and discuss its theoretical properties. The model framework allows Bayesian inference while maintaining a computational time that is competitive with common multivariate geostatistical approaches. In a numerical study, we find that the proposed model outperforms multivariate spatial Gaussian processes, multivariate spatial t-processes including their univariate alternatives in terms of various model selection criteria. We apply the proposed model to estimate the average decadal change in the extreme precipitation indexes throughout the United States and find several significant local changes.

    Comment: 23 pages, 6 Figures
    Keywords Statistics - Applications
    Subject code 910
    Publishing date 2018-12-31
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article: A Spatio-Temporal Model for Longitudinal Image-on-Image Regression.

    Hazra, Arnab / Reich, Brian J / Reich, Daniel S / Shinohara, Russell T / Staicu, Ana-Maria

    Statistics in biosciences

    2017  Volume 11, Issue 1, Page(s) 22–46

    Abstract: Neurologists and radiologists often use magnetic resonance imaging (MRI) in the management of subjects with multiple sclerosis (MS) because it is sensitive to inflammatory and demyelinative changes in the white matter of the brain and spinal cord. Two ... ...

    Abstract Neurologists and radiologists often use magnetic resonance imaging (MRI) in the management of subjects with multiple sclerosis (MS) because it is sensitive to inflammatory and demyelinative changes in the white matter of the brain and spinal cord. Two conventional modalities used for identifying lesions are T1-weighted (T1) and T2-weighted fluid-attenuated inversion recovery (FLAIR) imaging, which are used clinically and in research studies. Magnetization transfer ratio (MTR), which is available only in research settings, is an advanced MRI modality that has been used extensively for measuring disease-related demyelination both in white matter lesions as well across normal-appearing white matter. Acquiring MTR is not standard in clinical practice, due to the increased scan time and cost. Hence, prediction of MTR based on the modalities T1 and FLAIR could have great impact on the availability of these promising measures for improved patient management. We propose a spatio-temporal regression model for image response and image predictors that are acquired longitudinally, with images being co-registered within the subject but not across subjects. The model is additive, with the response at a voxel being dependent on the available covariates not only through the current voxel but also on the imaging information from the voxels within a neighboring spatial region as well as their temporal gradients. We propose a dynamic Bayesian estimation procedure that updates the parameters of the subject-specific regression model as data accummulates. To bypass the computational challenges associated with a Bayesian approach for high-dimensional imaging data, we propose an approximate Bayesian inference technique. We assess the model fitting and the prediction performance using longitudinally acquired MRI images from 46 MS patients.
    Language English
    Publishing date 2017-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2497694-5
    ISSN 1867-1772 ; 1867-1764
    ISSN (online) 1867-1772
    ISSN 1867-1764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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