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  1. Article ; Online: Sandwich electrochemical thrombin assay using a glassy carbon electrode modified with nitrogen- and sulfur-doped graphene oxide and gold nanoparticles.

    He, Baoshan

    Mikrochimica acta

    2018  Volume 185, Issue 7, Page(s) 344

    Abstract: Graphene oxide doped with nitrogen and sulfur was decorated with gold nanoparticles (AuNP-SN-GO) and applied as a substrate to modify a glassy carbon electrode (GCE). An aptamer against the model protein thrombin was self-assembled on the modified GCE ... ...

    Abstract Graphene oxide doped with nitrogen and sulfur was decorated with gold nanoparticles (AuNP-SN-GO) and applied as a substrate to modify a glassy carbon electrode (GCE). An aptamer against the model protein thrombin was self-assembled on the modified GCE which then was exposed to thrombin. Following aptamer-thrombin interaction, biotin-labeled DNA and aptamer 2 are immobilized on another AuNP-SN-GO hybrid and then are reacted with the thrombin/AuNP-SN-GO/GCE to form a sandwich. The enzyme label horseradish peroxidase (HRP) was then attached to the electrode by biotin-avidin interaction. HRP catalyzes the oxidation of hydroquinone by hydrogen peroxide. This generates a strong electrochemical signal that increases linearly with the logarithm of thrombin concentration in the range from 1.0 × 10
    Language English
    Publishing date 2018-06-28
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-018-2872-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 56/171: Show issues
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  2. Article ; Online: A "signal off" aptasensor based on NiFe

    He, Baoshan / Wang, Kai

    Mikrochimica acta

    2021  Volume 188, Issue 1, Page(s) 23

    Abstract: A "signal off" aptasensor has been developed to detect deoxynivalenol (DON). DON aptamers (Apt) were used as biological recognition elements, nickel ferrite nanotubes ( ... ...

    Abstract A "signal off" aptasensor has been developed to detect deoxynivalenol (DON). DON aptamers (Apt) were used as biological recognition elements, nickel ferrite nanotubes (NiFe
    MeSH term(s) Aptamers, Nucleotide/chemistry ; Biosensing Techniques/methods ; DNA, Complementary/chemistry ; Edible Grain/chemistry ; Electrochemical Techniques/methods ; Ferric Compounds/chemistry ; Flour ; Food Contamination/analysis ; Gold/chemistry ; Immobilized Nucleic Acids/chemistry ; Limit of Detection ; Nanotubes/chemistry ; Nickel/chemistry ; Phenothiazines/chemistry ; Platinum/chemistry ; Reproducibility of Results ; Trichothecenes/analysis ; Zea mays/chemistry
    Chemical Substances Aptamers, Nucleotide ; DNA, Complementary ; Ferric Compounds ; Immobilized Nucleic Acids ; Phenothiazines ; Trichothecenes ; nickel ferrite ; Platinum (49DFR088MY) ; Gold (7440-57-5) ; Nickel (7OV03QG267) ; deoxynivalenol (JT37HYP23V) ; thionine (VTT2SAT5H0)
    Language English
    Publishing date 2021-01-06
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-020-04666-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 56/171: Show issues
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  3. Article ; Online: An electrochemical aptasensor based on PEI-C

    He, Baoshan / Wang, Senyao

    Mikrochimica acta

    2021  Volume 188, Issue 1, Page(s) 22

    Abstract: An electrochemical aptasensor, including the polyethyleneimine-graphite-like carbon nitride/Au nanowire nanocomposite (PEI- ... ...

    Abstract An electrochemical aptasensor, including the polyethyleneimine-graphite-like carbon nitride/Au nanowire nanocomposite (PEI-C
    MeSH term(s) Animals ; Aptamers, Nucleotide/chemistry ; Biosensing Techniques/methods ; Chloramphenicol/analysis ; Chloramphenicol/chemistry ; Electrochemical Techniques/methods ; Electrodes ; Exonucleases/chemistry ; Food Contamination/analysis ; Gold/chemistry ; Graphite/chemistry ; Immobilized Nucleic Acids/chemistry ; Limit of Detection ; Milk/chemistry ; Nanowires/chemistry ; Nitrogen Compounds/chemistry ; Polyethyleneimine/chemistry ; Reproducibility of Results ; Water Pollutants, Chemical/analysis ; Water Pollutants, Chemical/chemistry
    Chemical Substances Aptamers, Nucleotide ; Immobilized Nucleic Acids ; Nitrogen Compounds ; Water Pollutants, Chemical ; graphitic carbon nitride ; Chloramphenicol (66974FR9Q1) ; Gold (7440-57-5) ; Graphite (7782-42-5) ; Polyethyleneimine (9002-98-6) ; Exonucleases (EC 3.1.-)
    Language English
    Publishing date 2021-01-06
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-020-04688-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 56/171: Show issues
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  4. Article ; Online: Effect of sanxan on the composition and structure properties of gluten in salt-free frozen-cooked noodles during freeze-thaw cycles.

    Liang, Ying / Zhu, Xiuling / Liu, Hao / Wang, Jiayi / He, Baoshan / Wang, Jinshui

    Food chemistry: X

    2024  Volume 21, Page(s) 101229

    Abstract: In this study, the mechanisms by which sanxan protected the quality of salt-free frozen-cooked noodles (SFFCNs) were investigated, with a focus on the composition and structural properties of gluten. The results showed that sanxan facilitated the ... ...

    Abstract In this study, the mechanisms by which sanxan protected the quality of salt-free frozen-cooked noodles (SFFCNs) were investigated, with a focus on the composition and structural properties of gluten. The results showed that sanxan facilitated the formation of glutenin macropolymer and maintained the stabilization of glutenin subunits in freeze-thaw cycles (FTs). In terms of protein structure, sanxan weakened the disruption of secondary structure caused by FTs and increased the proportion of
    Language English
    Publishing date 2024-02-15
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-1575
    ISSN (online) 2590-1575
    DOI 10.1016/j.fochx.2024.101229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effects of sanxan on water and ice crystal status of salt free frozen cooked noodles during freeze-thaw cycles.

    Liang, Ying / Cao, Zhihui / Wang, Jiayi / Jie, Yangyi / Liu, Hao / He, Baoshan / Wang, Jinshui

    Food chemistry

    2024  Volume 448, Page(s) 139137

    Abstract: This study compared four biocolloids (sanxan, xanthan gum, curdlan, and guar gum) in different concentrations to replace NaCl in improving the recooking quality of salt free frozen cooked noodles (SF-FCNs). Sanxan outperformed NaCl and other biocolloids ... ...

    Abstract This study compared four biocolloids (sanxan, xanthan gum, curdlan, and guar gum) in different concentrations to replace NaCl in improving the recooking quality of salt free frozen cooked noodles (SF-FCNs). Sanxan outperformed NaCl and other biocolloids significantly improving the firmness (21.0%), chewiness (63.5%), and toughness (15.4%) of SF-FCNs after 10 freeze-thaw (FT) cycles. The results of the freezing-thawing curves showed SF-FCNs had prior FT stability when sanxan was added at 1.2%. Subsequently, the result of differential scanning calorimetry and nuclear magnetic resonance revealed sanxan reduced the content and mobility of freezable water while increasing the content of bound water. The scanning electron microscope, mercury intrusion, and optical microscopy analyses indicated that sanxan reduced the size and volume of ice crystals and the structural damage of SF-FCNs by controlling the water. The work contributes to a theoretical framework for enhancing SF-FCNs quality through precise water and ice crystal control.
    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2024.139137
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    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

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  6. Article ; Online: Amyloid-like Aggregation of Wheat Gluten and Its Components during Cooking: Mechanisms and Structural Characterization.

    Liang, Ying / Liu, Hao / Jie, Yangyi / Liu, Mei / He, Baoshan / Wang, Jinshui

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 19, Page(s) 11080–11093

    Abstract: Amyloid-like aggregation widely occurs during the processing and production of natural proteins, with evidence indicating its presence following the thermal processing of wheat gluten. However, significant gaps remain in understanding the underlying ... ...

    Abstract Amyloid-like aggregation widely occurs during the processing and production of natural proteins, with evidence indicating its presence following the thermal processing of wheat gluten. However, significant gaps remain in understanding the underlying fibrillation mechanisms and structural polymorphisms. In this study, the amyloid-like aggregation behavior of wheat gluten and its components (glutenin and gliadin) during cooking was systematically analyzed through physicochemical assessment and structural characterization. The presence of amyloid-like fibrils (AFs) was confirmed using X-ray diffraction and Congo red staining, while Thioflavin T fluorescence revealed different patterns and rates of AFs growth among wheat gluten, glutenin, and gliadin. AFs in gliadin exhibited linear growth curves, while those in gluten and glutenin showed S-shaped curves, with the shortest lag phase and fastest growth rate (
    MeSH term(s) Glutens/chemistry ; Triticum/chemistry ; Cooking ; Amyloid/chemistry ; Gliadin/chemistry ; Hot Temperature ; Protein Aggregates ; Molecular Weight ; X-Ray Diffraction
    Language English
    Publishing date 2024-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c09451
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: A label-free electrochemical aptasensor based on NH₂-MIL-235(Fe) for the sensitive detection of citrinin

    Yan, Haoyang / He, Baoshan / Xie, Lingling / Cao, Xiaoyu

    Analytical methods. 2022 Sept. 29, v. 14, no. 37

    2022  

    Abstract: This study successfully developed a simple, specific, and ultrasensitive electrochemical aptasensor based on a label-free strategy for detecting citrinin (CIT). The NH₂–Fe-MOF nanomaterial has a large specific surface area, good biocompatibility, a ... ...

    Abstract This study successfully developed a simple, specific, and ultrasensitive electrochemical aptasensor based on a label-free strategy for detecting citrinin (CIT). The NH₂–Fe-MOF nanomaterial has a large specific surface area, good biocompatibility, a simple preparation method, and low synthesis cost, so it was chosen as the aptamer's loading platform to improve the detection performance of the sensor. When CIT is present, the aptamer will specifically bind to it with a conformational change that prevents electron transfer to the electrode surface. Based on this, CIT could be quantitatively detected by measuring the change of differential pulse voltammetric (DPV) responses of the [Fe(CN)₆]³⁻/⁴⁻ peak current. Under optimized experimental conditions, the proposed aptasensor showed a low detection limit of 4.52 × 10⁻¹¹ g mL⁻¹ and a wide linear range of 0.1 to 1 × 10⁴ ng mL⁻¹. Furthermore, the proposed aptasensor shows excellent selectivity, reliable stability, and significant potential for the ultrasensitive detection of CIT in practical applications.
    Keywords aptasensors ; biocompatibility ; citrinin ; detection limit ; electrochemistry ; electrodes ; electron transfer ; nanomaterials ; oligonucleotides ; surface area ; voltammetry
    Language English
    Dates of publication 2022-0929
    Size p. 3702-3708.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2515210-5
    ISSN 1759-9679 ; 1759-9660
    ISSN (online) 1759-9679
    ISSN 1759-9660
    DOI 10.1039/d2ay01243j
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Latest strategies for rapid and point of care detection of mycotoxins in food: A review.

    Suo, Zhiguang / Niu, Xingyuan / Wei, Min / Jin, Huali / He, Baoshan

    Analytica chimica acta

    2023  Volume 1246, Page(s) 340888

    Abstract: Mycotoxins contaminated in agricultural products are often highly carcinogenic and genotoxic to humans. With the streamlining of the food industry chain and the improvement of food safety requirements, the traditional laboratory testing mode is ... ...

    Abstract Mycotoxins contaminated in agricultural products are often highly carcinogenic and genotoxic to humans. With the streamlining of the food industry chain and the improvement of food safety requirements, the traditional laboratory testing mode is constantly challenged due to the expensive equipment, complex operation steps, and lag in testing results. Therefore, rapid detection methods are urgently needed in the food safety system. This review focuses on the latest strategies that can achieve rapid and on-site testing, with particular attention to the nanomaterials integrated biosensors. To provide researchers with the latest trends and inspiration in the field of rapid detection, we summarize several strategies suitable for point of care testing (POCT) of mycotoxins, including enzyme-linked immunoassay (ELISA), lateral flow assay (LFA), fluorescence, electrochemistry, and colorimetry assay. POCT-based strategies are all developing towards intelligence and portability, especially when combined with smartphones, making it easier to read signals for intuitive access and analysis of test data. Detection performance of the devices has also improved considerably with the integration of biosensors and nanomaterials.
    MeSH term(s) Humans ; Point-of-Care Systems ; Mycotoxins/analysis ; Point-of-Care Testing ; Biosensing Techniques ; Nanostructures ; Immunoassay/methods
    Chemical Substances Mycotoxins
    Language English
    Publishing date 2023-01-24
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1483436-4
    ISSN 1873-4324 ; 0003-2670
    ISSN (online) 1873-4324
    ISSN 0003-2670
    DOI 10.1016/j.aca.2023.340888
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  9. Article ; Online: A label-free electrochemical aptasensor based on NH

    Yan, Haoyang / He, Baoshan / Xie, Lingling / Cao, Xiaoyu

    Analytical methods : advancing methods and applications

    2022  Volume 14, Issue 37, Page(s) 3702–3708

    Abstract: This study successfully developed a simple, specific, and ultrasensitive electrochemical aptasensor based on a label-free strategy for detecting citrinin (CIT). The ... ...

    Abstract This study successfully developed a simple, specific, and ultrasensitive electrochemical aptasensor based on a label-free strategy for detecting citrinin (CIT). The NH
    MeSH term(s) Aptamers, Nucleotide/chemistry ; Biosensing Techniques/methods ; Citrinin ; Electrochemical Techniques/methods
    Chemical Substances Aptamers, Nucleotide ; Citrinin (3S697X6SNZ)
    Language English
    Publishing date 2022-09-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2515210-5
    ISSN 1759-9679 ; 1759-9660
    ISSN (online) 1759-9679
    ISSN 1759-9660
    DOI 10.1039/d2ay01243j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: An electrochemical aptasensor based on tetrahedral DNA nanostructures as a signal probe carrier platform for sensitive detection of patulin.

    He, Baoshan / Lu, Xia

    Analytica chimica acta

    2020  Volume 1138, Page(s) 123–131

    Abstract: In this work, we proposed an electrochemical aptasensor for patulin (PAT) based on tetrahedral DNA nanostructures (TDNs) and thionine (Thi)-labeled ... ...

    Abstract In this work, we proposed an electrochemical aptasensor for patulin (PAT) based on tetrahedral DNA nanostructures (TDNs) and thionine (Thi)-labeled Fe
    MeSH term(s) Aptamers, Nucleotide ; Biosensing Techniques ; DNA ; Electrochemical Techniques ; Gold ; Graphite ; Limit of Detection ; Nanostructures ; Patulin ; Reproducibility of Results
    Chemical Substances Aptamers, Nucleotide ; Gold (7440-57-5) ; Graphite (7782-42-5) ; DNA (9007-49-2) ; Patulin (95X2BV4W8R)
    Language English
    Publishing date 2020-09-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1483436-4
    ISSN 1873-4324 ; 0003-2670
    ISSN (online) 1873-4324
    ISSN 0003-2670
    DOI 10.1016/j.aca.2020.09.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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