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Article ; Online: The relation between family socioeconomic status and depressive symptoms among children and adolescents in mainland China

Yingnan Niu / Xiaolin Guo / He Cai / Liang Luo

Frontiers in Public Health, Vol

a meta-analysis

2024 Volume 11

Abstract: Family socioeconomic status (SES) is widely believed to be associated with depressive symptoms in children and adolescents. The correlation between SES and depressive symptoms changes based on social culture and the economic development level. In China, ... ...

Abstract	Family socioeconomic status (SES) is widely believed to be associated with depressive symptoms in children and adolescents. The correlation between SES and depressive symptoms changes based on social culture and the economic development level. In China, which includes many children and adolescents, the magnitude of the relationship between SES and depressive symptoms and its potential moderators remains unclear. The current meta-analysis was conducted to determine the overall association between SES and depressive symptoms in children and adolescents in mainland China. We included 197 estimates in mainland China from 2000–2023. Among 147,613 children and adolescents aged 7–18 years, the results showed a weak but significant overall negative association between SES and depression (r = −0.076). Moderator testing showed that the composite SES indicator (r = −0.104) had a stronger association with depression than parental educational level (r = −0.065) and occupational status (r = −0.025) but not family income (r = −0.088). Additionally, the negative association between SES and depression became weaker over the past 20 years in China (β = 0.010). Furthermore, the magnitude of the relationship between SES and depression was stronger in West China (r = −0.094) than in Middle China (r = −0.065), but not East China (r = −0.075). These findings indicate that the relationship between SES and depression among children and adolescents in mainland China may vary based on social contexts. It is necessary to further explore the effect of these social factors and the underlying mechanisms.
Keywords	socioeconomic status ; depressive symptoms ; children ; adolescents ; mainland China ; meta-analysis ; Public aspects of medicine ; RA1-1270
Subject code	950
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Sociodemographic Factors Related to Adverse Donor Reactions in Shenzhen.

Sun, Li-Yan / Yu, Qiong / He, Cai-Ming / Wang, Song-Xing

International journal of general medicine

2023 Volume 16, Page(s) 5493–5499

Abstract: Background: The adverse donor reaction (ADR) means the uncomfortable feeling felt by blood donors during the whole process of blood donation, which can affect the blood donation behavior of blood donors. So, it is very necessary for blood centers to ... ...

Abstract	Background: The adverse donor reaction (ADR) means the uncomfortable feeling felt by blood donors during the whole process of blood donation, which can affect the blood donation behavior of blood donors. So, it is very necessary for blood centers to monitor and prevent it. Methods: Data about ADRs in Shenzhen Blood Center from January 2018 to December 2022 were collected, and correlation analysis was conducted using SPSS 24.0 software. Results: From January 2018 to December 2022, a total of 1265 ADRs occurred in 642,767 blood donations in Shenzhen Blood Center, with an incidence of 0.20%. Most of the ADRs were mild and occurred during blood collections (>90%). The ADR rate of young individuals aged 18-29 years old was the highest ( Conclusion: The occurrence of ADRs is related to the sociodemographic factors of blood donors, including age, donation type, donation history, and donation sites. Shenzhen Blood Centers should pay special attention to the process of blood donation among young blood donors aged 18-29 years old, first-time blood donors, whole-blood donors, and blood donors who donate at mobile sites to further reduce the occurrence of ADRs.
Language	English
Publishing date	2023-11-23
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2452220-X
ISSN	1178-7074
ISSN	1178-7074
DOI	10.2147/IJGM.S443682
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Research progress in spike mutations of SARS-CoV-2 variants and vaccine development.

He, Xuemei / He, Cai / Hong, Weiqi / Yang, Jingyun / Wei, Xiawei

Medicinal research reviews

2023 Volume 43, Issue 4, Page(s) 932–971

Abstract: The coronavirus disease 2019 (COVID-19) pandemic can hardly end with the emergence of different variants over time. In the past 2 years, several variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), such as the Delta and Omicron ... ...

Abstract	The coronavirus disease 2019 (COVID-19) pandemic can hardly end with the emergence of different variants over time. In the past 2 years, several variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), such as the Delta and Omicron variants, have emerged with higher transmissibility, immune evasion and drug resistance, leading to higher morbidity and mortality in the population. The prevalent variants of concern (VOCs) share several mutations on the spike that can affect virus characteristics, including transmissibility, antigenicity, and immune evasion. Increasing evidence has demonstrated that the neutralization capacity of sera from COVID-19 convalescent or vaccinated individuals is decreased against SARS-CoV-2 variants. Moreover, the vaccine effectiveness of current COVID-19 vaccines against SARS-CoV-2 VOCs is not as high as that against wild-type SARS-CoV-2. Therefore, more attention might be paid to how the mutations impact vaccine effectiveness. In this review, we summarized the current studies on the mutations of the SARS-CoV-2 spike, particularly of the receptor binding domain, to elaborate on how the mutations impact the infectivity, transmissibility and immune evasion of the virus. The effects of mutations in the SARS-CoV-2 spike on the current therapeutics were highlighted, and potential strategies for future vaccine development were suggested.
MeSH term(s)	Humans ; SARS-CoV-2/genetics ; COVID-19/prevention & control ; COVID-19 Vaccines/genetics ; Vaccine Development ; Mutation
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-03-16
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	603210-2
ISSN	1098-1128 ; 0198-6325
ISSN (online)	1098-1128
ISSN	0198-6325
DOI	10.1002/med.21941
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Article ; Online: Duration of infertility and assisted reproductive outcomes in non-male factor infertility

Liting Zhang / He Cai / Wei Li / Li Tian / Juanzi Shi

BMC Women's Health, Vol 22, Iss 1, Pp 1-

can use of ICSI turn the tide?

2022 Volume 9

Abstract: Abstract Background Intracytoplasmic sperm injection (ICSI) is increasingly used among in vitro fertilization (IVF) cycles without male factor infertility. For couples with prolonged infertility duration, the preferred insemination method may vary across ...

Abstract	Abstract Background Intracytoplasmic sperm injection (ICSI) is increasingly used among in vitro fertilization (IVF) cycles without male factor infertility. For couples with prolonged infertility duration, the preferred insemination method may vary across laboratories and clinics. We analyzed whether ICSI is effective for non-male factor infertility with long infertility duration. Methods Seventeen thousand four hundred seventy-seven IVF/ICSI cycles from women with non-male factor infertility were included, of these 4177 women with infertility duration ≥ 5 years were in the final analysis. Primary outcome was the live birth rate after first embryo transfer. Secondary outcomes were rates of clinical pregnancy and fertilization. Results A nonlinear relationship was observed between infertility duration and IVF fertilization rate, which decreased with infertility years up to the turning point (4.8 years). 4177 women with infertility ≥ 5 years were categorized by IVF (n = 3806) or ICSI (n = 371). Live birth rate after first embryo transfer was 43.02% in ICSI and 47.85% in IVF group (adjusted odds ratio (aOR), 0.91; 95% confidence interval (CI), 0.72–1.15). Fertilization rate per metaphaseII (aOR, 1.10; 95% CI, 0.86–1.40) and clinical pregnancy rate (aOR, 0.89; 95% CI, 0.71–1.13) were similar between the two groups. Sensitive analyses (women ≥ 35 years) did not show a benefit of ICSI over IVF. Conclusions Women with infertility exceeding 4.8 years had decreased incidence of IVF fertilization. The use of ICSI showed no significant improvement in fertilization and live birth rates for non-male factor couples with ≥ 5 years of infertility.
Keywords	Duration of infertility ; ICSI ; Non-male factor ; Fertilization ; Live birth ; Gynecology and obstetrics ; RG1-991 ; Public aspects of medicine ; RA1-1270
Subject code	306
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Metal-based nano-delivery platform for treating bone disease and regeneration

Yanhua Liu / Zhengyi Xu / Mingxin Qiao / He Cai / Zhou Zhu

Frontiers in Chemistry, Vol

2022 Volume 10

Abstract: Owing to their excellent characteristics, such as large specific surface area, favorable biosafety, and versatile application, nanomaterials have attracted significant attention in biomedical applications. Among them, metal-based nanomaterials containing ...

Abstract	Owing to their excellent characteristics, such as large specific surface area, favorable biosafety, and versatile application, nanomaterials have attracted significant attention in biomedical applications. Among them, metal-based nanomaterials containing various metal elements exhibit significant bone tissue regeneration potential, unique antibacterial properties, and advanced drug delivery functions, thus becoming crucial development platforms for bone tissue engineering and drug therapy for orthopedic diseases. Herein, metal-based drug-loaded nanomaterial platforms are classified and introduced, and the achievable drug-loading methods are comprehensively generalized. Furthermore, their applications in bone tissue engineering, osteoarthritis, orthopedic implant infection, bone tumor, and joint lubrication are reviewed in detail. Finally, the merits and demerits of the current metal-based drug-loaded nanomaterial platforms are critically discussed, and the challenges faced to realize their future applications are summarized.
Keywords	metal-based nanocarriers ; drug deivlery ; bone disease ; bone regeneration ; tissue engineering ; Chemistry ; QD1-999
Subject code	670
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: High-Light-Induced Degradation of Photosystem II Subunits’ Involvement in the Albino Phenotype in Tea Plants

Wen-He Cai / Xin-Qiang Zheng / Yue-Rong Liang

International Journal of Molecular Sciences, Vol 23, Iss 15, p

2022 Volume 8522

Abstract: The light-sensitive (LS) albino tea plant grows albinic shoots lacking chlorophylls (Chls) under high-light (HL) conditions, and the albinic shoots re-green under low light (LL) conditions. The albinic shoots contain a high level of amino acids and are ... ...

Abstract	The light-sensitive (LS) albino tea plant grows albinic shoots lacking chlorophylls (Chls) under high-light (HL) conditions, and the albinic shoots re-green under low light (LL) conditions. The albinic shoots contain a high level of amino acids and are preferential materials for processing quality green tea. The young plants of the albino tea cultivars are difficult to be cultivated owing to lacking Chls. The mechanisms of the tea leaf bleaching and re-greening are unknown. We detected the activity and composition of photosystem II (PSII) subunits in LS albino tea cultivar “Huangjinya” (HJY), with a normal green-leaf cultivar “Jinxuan” (JX) as control so as to find the relationship of PSII impairment to the albino phenotype in tea. The PSII of HJY is more vulnerable to HL-stress than JX. HL-induced degradation of PSII subunits CP43, CP47, PsbP, PsbR. and light-harvest chlorophyll–protein complexes led to the exposure and degradation of D1 and D2, in which partial fragments of the degraded subunits were crosslinked to form larger aggregates. Two copies of subunits PsbO, psbN, and Lhcb1 were expressed in response to HL stress. The cDNA sequencing of CP43 shows that there is no difference in sequences of PsbC cDNA and putative amino acids of CP43 between HJY and JX. The de novo synthesis and/or repair of PSII subunits is considered to be involved in the impairment of PSII complexes, and the latter played a predominant role in the albino phenotype in the LS albino tea plant.
Keywords	Camellia sinensis ; albino tea ; photosystem II ; photodamage ; thylakoid ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	580
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Feasibility of the Application of Common Law Double Tier Model in China from the Burden of Proof Perspective

He CAI

Canadian Social Science, Vol 9, Iss 4, Pp 57-

2013 Volume 62

Abstract: Since just cause and other behaviors that exclude social harmfulness are not included in constitution of a crime, the distribution of burden of proof is not clear. Behaviors that exclude social harmfulness is the content of the defense of just cause in ... ...

Abstract	Since just cause and other behaviors that exclude social harmfulness are not included in constitution of a crime, the distribution of burden of proof is not clear. Behaviors that exclude social harmfulness is the content of the defense of just cause in British and American double tier model and the burden of proof is clear. We cannot introduce or borrow the British and American double tier model to clearly exclude the burden of proof of behaviors which have social harmfulness for it could lead to the increase of the accused’s burden of proof and therefore causes inability of proofing, the burden of proof of both the prosecuting and defending parties mixed and conflict, and no way for bearing the burden of proof for the accused.
Keywords	The constitution of a crime ; Behaviors that exclude social harmfulness ; Double tier model ; Burden of proof ; Social Sciences ; H ; Social sciences (General) ; H1-99
Subject code	004
Publishing date	2013-08-01T00:00:00Z
Publisher	Canadian Academy of Oriental and Occidental Culture
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comparison of general and aesthetic effects between flapless and flap techniques in dental implantation

Xiaomeng Gao / Siyu Qin / He Cai / Qianbing Wan

International Journal of Implant Dentistry, Vol 7, Iss 1, Pp 1-

a meta-analysis of randomized controlled trials

2021 Volume 13

Abstract: Abstract Background Information about the aesthetic effects of flapless in implant surgeries is scant. Differences of the survival rate (SR) and crestal bone loss (CBL) between the two techniques were also controversial. Thus, this review was aimed to ... ...

Abstract	Abstract Background Information about the aesthetic effects of flapless in implant surgeries is scant. Differences of the survival rate (SR) and crestal bone loss (CBL) between the two techniques were also controversial. Thus, this review was aimed to compare the general and aesthetic effects of flapless and flap approaches in implant surgeries. Materials and methods Following the principals of PRISMA, literature databases were searched for the eligible randomized controlled trials (RCTs) comparing the clinical performances of flap and flapless techniques. After that, relevant data of selected studies were pooled and analyzed to compare SR, bleeding on probing (BOP), probing depth (PD), visual analogue scale (VAS), papillae presentation index (PPI), keratinized mucosa (KM) width and CBL between the two techniques. Results Fourteen RCTs were included. No significant difference was found in SR (RR = − 0.01, 95% confidence interval (CI) (− 0.05, 0.04)), BOP (OR = 0.40, 95% CI (0.15, 1.02)), KM width (WMD = − 0.42, 95% CI (− 1.02, 0.17)) between two groups. Subgroup analysis revealed that the difference of CBL was insignificant in two groups (WMD = − 0.13, 95% CI (− 0.63, 0.38)). However, flap techniques would lead more peri-implant PD (WMD = − 0.37, 95% CI (− 0.51, − 0.23)). Subgroup analysis also indicated lower VAS scores in flapless group after 1 day (WMD = − 1.66, 95% CI (− 2.16, − 1.16)) but comparable pain experience after 3 days (WMD = − 0.59, 95% CI (− 1.33, 0.16)). Mean difference of PPI (WMD = 0.32, 95% CI (0.28, 0.35)) between the two groups was significant. Conclusions The flapless procedure showed a superiority in preserving gingival papillae, reducing postoperative pain and peri-implant PD compared to the flap procedure, while exhibiting comparable effects on SR, BOP, KW width changes and CBL. Flapless technique is more recommended at the ideal soft and hard tissue implanting sites.
Keywords	Flapless ; Flap ; Aesthetics ; Dental implants ; Meta-analysis ; Medicine ; R ; Dentistry ; RK1-715
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of the Paralympic Games on the Beliefs of Children with Physical Disabilities Engaging in Sports and Physical Activities

Jing Qi / Jin-He Cai / Xun Meng

International Journal of Environmental Research and Public Health, Vol 18, Iss 7296, p

A Chinese Perspective

2021 Volume 7296

Abstract: The purpose of this qualitative study was to explore the beliefs of Chinese children with physical disabilities engaging in sports and physical activity (PA), and the impact of the Paralympic Games on these beliefs. Five Chinese children with physical ... ...

Abstract	The purpose of this qualitative study was to explore the beliefs of Chinese children with physical disabilities engaging in sports and physical activity (PA), and the impact of the Paralympic Games on these beliefs. Five Chinese children with physical disabilities (female = 2, male = 3) were recruited for participating in the workshops of the Paralympic Games and PA, and received individual semi-structured interviews before and after the workshop implementations. Interview transcripts were analysed and presented as descriptive summaries. Three themes emerged based on the analysis of the participants’ interview data: (1) shocked, knowledgeable, and useful; (2) willingness to try, and (3) hope to obtain support. Results indicated that children with physical disabilities in this study acknowledged the positive outcomes of participating in the workshops of the Paralympic Games on the sports and PA engagement attitude change. However, children with disabilities also expressed that they need more related knowledge and information. The results of the study revealed that impairment and contextual factors (i.e., lack of support from family and physical education teachers, unsafe environments, and negative attitudes of peers without disabilities) were barriers to sports and PA engagement among children with physical disabilities in this study.
Keywords	Paralympic Games ; Beijing 2008 ; legacy ; beliefs ; physical activity ; Medicine ; R
Subject code	796
Language	English
Publishing date	2021-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Research on the actual combat maintenance and support capability system of aerospace equipment

LI Pei-yue, ZHANG Yong-fu, LI He-cai

Zhihui kongzhi yu fangzhen, Vol 45, Iss 1, Pp 21-

2023 Volume 28

Abstract: The complexity of the war and the density of high and new technologies have led to an increasing demand for the maintenance and support of space equipment in actual combat. The traditional maintenance support capability system is difficult to meet the ... ...

Abstract	The complexity of the war and the density of high and new technologies have led to an increasing demand for the maintenance and support of space equipment in actual combat. The traditional maintenance support capability system is difficult to meet the dynamic and complex maintenance support needs. By analyzing the factors and relationships generated by the actual combat maintenance and support capability of aerospace equipment, the idea of constructing a capability system based on the decomposition of maintenance support activities is proposed, and the improved gray correlation analysis method is used to optimize, and the optimized maintenance support capability system is obtained. The research can provide a reference for the generation of actual combat maintenance support capability of aerospace equipment.
Keywords	aerospace equipment\|actual combat\|maintenance support\|capability system ; Military Science ; U
Subject code	690
Language	Chinese
Publishing date	2023-02-01T00:00:00Z
Publisher	Editorial Office of Command Control and Simulation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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