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  1. Article ; Online: Episode Payment Models and Provider Consolidation: Evidence From the Comprehensive Care for Joint Replacement Model.

    He, Fang

    Medical care research and review : MCRR

    2023  Volume 80, Issue 4, Page(s) 396–409

    Abstract: A possible unintended consequence of episode payment models is provider consolidation, which can, in turn, increase prices for commercially insured enrollees. We assess the effect of Medicare's Comprehensive Care for Joint Replacement (CJR) model on ... ...

    Abstract A possible unintended consequence of episode payment models is provider consolidation, which can, in turn, increase prices for commercially insured enrollees. We assess the effect of Medicare's Comprehensive Care for Joint Replacement (CJR) model on provider consolidation. Hospitals in randomly assigned metropolitan statistical areas were mandated to participate during the first 2 years of the model and a subset of hospitals were mandated for later years. We used a difference-in-differences approach to assess whether CJR affected consolidation, as measured by hospital ownership of practices, the number and size of practices, the Herfindahl-Hirschman Index, and the four-firm concentration ratio. Given limited sample sizes, our results are only suggestive that CJR was not associated with changes in consolidation. Our strongest results suggest null effects for changes in hospital ownership and practice size. These findings suggest that concerns regarding the role alternative payment models play in consolidation may have been overstated.
    MeSH term(s) Aged ; Humans ; United States ; Medicare ; Arthroplasty, Replacement ; Hospitals ; Comprehensive Health Care ; Patient Care Bundles
    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1232314-7
    ISSN 1552-6801 ; 1077-5587
    ISSN (online) 1552-6801
    ISSN 1077-5587
    DOI 10.1177/10775587231160912
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Expression of miRNA-29c in the carotid plaque and its association with diabetic mellitus.

    Wang, Hua / Mai, Peipei / He, Fang / Zhang, Yanfang

    Frontiers in cardiovascular medicine

    2024  Volume 11, Page(s) 1276066

    Abstract: Background: Carotid artery atherosclerosis is a major cause of ischemic stroke, and ischemic stroke is the leading cause of morbidity and mortality worldwide. Unfortunately, the reason for the build-up of atherosclerosis plaque is unknown. The miRNA-29c ...

    Abstract Background: Carotid artery atherosclerosis is a major cause of ischemic stroke, and ischemic stroke is the leading cause of morbidity and mortality worldwide. Unfortunately, the reason for the build-up of atherosclerosis plaque is unknown. The miRNA-29c was reported to promote the phenotype transformation of vascular smooth muscle cells (VSMCs) in diabetes mice, eventually leading to plaque formation and bleeding. However, such studies are rare and limited to animal experiments.
    Methods: In our study, 40 patients were divided into a diabetic mellitus (DM) group and a non-DM group according to whether they were diagnosed with DM. Then, the real-time quantitative PCR was applied to examine the miRNA-29c level in human carotid plaque tissue derived from 40 subjects receiving carotid endarterectomy.
    Results: Briefly, diabetes patients had a decreased miRNA-29c level as compared with non-DM subjects, and this comparison was statistically significant (
    Conclusion: Collectively, the miRNA-29c level in the carotid plaque is closely associated with DM and cerebral stroke, which may contribute to atherosclerosis formation.
    Language English
    Publishing date 2024-02-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2024.1276066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A Study of Elderly Patients' Preference for "Internet + Nursing Service" Based on Discrete Choice Experiments.

    Liu, Cui / Zhang, Zhixia / Chen, Qiuxia / He, Fang

    Alternative therapies in health and medicine

    2024  

    Abstract: Objective: To investigate the preference of elderly patients for "Internet + Nursing Service", so as to provide reference for accurately matching their service needs.: Methods: Based on discrete choice experiments, the elderly patients' "Internet + ... ...

    Abstract Objective: To investigate the preference of elderly patients for "Internet + Nursing Service", so as to provide reference for accurately matching their service needs.
    Methods: Based on discrete choice experiments, the elderly patients' "Internet + Nursing Service" choice preference questionnaire was prepared, and 410 elderly patients were interviewed face-to-face. The Conditional Logit Model was used for quantitative analysis of the experimental data.
    Results: The six attributes included in the study had a significant impact on the elderly patients' preference for "Internet + Nursing Service" (P < .05). Among non-economic attributes, "medical insurance reimbursement ratio -70%" has the highest utility (.263, P < .001), with "hospital size - larger (.205, P < .05)" and "medical insurance reimbursement ratio -50%" (.188, P < .05) ranking second and third, respectively. The relative importance of the attribute of medical insurance reimbursement proportion is the highest (26.44%), and the relative importance of service content is the lowest (9.78%). If the proportion of medical insurance reimbursement increases from 30% to 70%, patients are willing to pay 202.9 yuan, and the probability of choosing "Internet + Nursing Service" increases by 6.1%.
    Conclusion: Patients prefer to choose a higher proportion of medical insurance reimbursement, a larger medical institution, a higher level of nurses, low single service costs, a basic package, and "Internet + Nursing Service" led by the government and hospitals. Improvement of the price and medical insurance payment policy is recommended, along with the enhancement of the ability of primary nursing services, strengthening of the management of Internet enterprise platforms, and scientific assessment of the needs of patients for personalized nursing services.
    Language English
    Publishing date 2024-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Molecularly imprinted electrochemiluminescence sensor based on a novel luminol derivative for detection of human serum albumin via click reaction.

    Li, Wei / Liu, Guangyan / He, Fang / Hou, Shili

    Mikrochimica acta

    2024  Volume 191, Issue 3, Page(s) 151

    Abstract: A novel luminol derivative of N-(1,4-dioxo-1,2,3,4-tetrahydrophthalazin-5-yl)acrylamide (DTA) with excellent luminescence efficiency was designed and synthesized. Furthermore, a molecularly imprinted electrochemiluminescence sensor (MIECLS) was ... ...

    Abstract A novel luminol derivative of N-(1,4-dioxo-1,2,3,4-tetrahydrophthalazin-5-yl)acrylamide (DTA) with excellent luminescence efficiency was designed and synthesized. Furthermore, a molecularly imprinted electrochemiluminescence sensor (MIECLS) was fabricated to detect ultratrace levels of human serum albumin (HSA) with high sensitivity and selectivity via a click reaction. The molecularly imprinted polymers (MIPs) were formed on the electrode surface via electropolymerization with HSA as a template molecule and catechol as a monomer. In the detection process, the -SH group of HSA on the electrode and the C = C bond of acryloyl group in DTA formed a new C-S bond via the Michael addition reaction to construct the MIECLS. The higher the concentration of HSA, the greater electrochemiluminescence (ECL) intensity measured. Taking advantage of MIECLS for ECL detection (scanning potential, - 0.4 to 0.5 V), there was a good linear relationship between ECL intensity and the logarithm of HSA concentration in the range 5 × 10
    MeSH term(s) Humans ; Luminol ; Acrylamide ; Electrochemical Techniques ; Electrodes ; Serum Albumin, Human
    Chemical Substances Luminol (5EXP385Q4F) ; Acrylamide (20R035KLCI) ; Serum Albumin, Human (ZIF514RVZR)
    Language English
    Publishing date 2024-02-22
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-024-06215-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nomogram establishment for short-term survival prediction in ICU patients with aplastic anemia based on the MIMIC-IV database.

    Tu, Yan / Zhang, Jingcheng / Zhao, Mingzhe / He, Fang

    Hematology (Amsterdam, Netherlands)

    2024  Volume 29, Issue 1, Page(s) 2339778

    Abstract: Objective: To establish an efficient nomogram model to predict short-term survival in ICU patients with aplastic anemia (AA).: Methods: The data of AA patients in the MIMIC-IV database were obtained and randomly assigned to the training set and ... ...

    Abstract Objective: To establish an efficient nomogram model to predict short-term survival in ICU patients with aplastic anemia (AA).
    Methods: The data of AA patients in the MIMIC-IV database were obtained and randomly assigned to the training set and testing set in a ratio of 7:3. Independent prognosis factors were identified through univariate and multivariate Cox regression analyses. The variance inflation factor was calculated to detect the correlation between variables. A nomogram model was built based on independent prognostic factors and risk scores for factors were generated. Model performance was tested using C-index, receiver operating characteristic (ROC) curve, calibration curve, decision curve analysis (DCA) and Kaplan-Meier curve.
    Results: A total of 1,963 AA patients were included. A nomogram model with 7 variables was built, including SAPS II, chronic pulmonary obstructive disease, body temperature, red cell distribution width, saturation of peripheral oxygen, age and mechanical ventilation. The C-indexes in the training set and testing set were 0.642 and 0.643 respectively, indicating certain accuracy of the model. ROC curve showed favorable classification performance of nomogram. The calibration curve reflected that its probabilistic prediction was reliable. DCA revealed good clinical practicability of the model. Moreover, the Kaplan-Meier curve showed that receiving mechanical ventilation could improve the survival status of AA patients in the short term but did not in the later period.
    Conclusion: The nomogram model of the short-term survival rate of AA patients was built based on clinical characteristics, and early mechanical ventilation could help improve the short-term survival rate of patients.
    MeSH term(s) Humans ; Anemia, Aplastic/diagnosis ; Anemia, Aplastic/therapy ; Nomograms ; Databases, Factual ; Erythrocyte Indices ; Intensive Care Units
    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1341428-8
    ISSN 1607-8454 ; 1024-5332 ; 1024-5340
    ISSN (online) 1607-8454
    ISSN 1024-5332 ; 1024-5340
    DOI 10.1080/16078454.2024.2339778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Systematic nursing interventions in gastric cancer: A randomized controlled study.

    He, Fang / He, Rui-Xian

    World journal of clinical cases

    2022  Volume 10, Issue 6, Page(s) 1843–1851

    Abstract: Background: Scientific and effective nursing methods can effectively mitigate negative emotions in patients. Related studies have shown that systematic nursing interventions are beneficial in enhancing the self-efficacy and self-care abilities of ... ...

    Abstract Background: Scientific and effective nursing methods can effectively mitigate negative emotions in patients. Related studies have shown that systematic nursing interventions are beneficial in enhancing the self-efficacy and self-care abilities of patients and improving their physical and mental state, thereby alleviating their fatigue and improving their quality of life.
    Aim: To explore the effects of systematic nursing intervention on cancer-related fatigue, self-efficacy, self-nursing ability, and quality of life in gastric cancer (GC) patients during the perioperative period.
    Methods: In this study, sample size was based on the multivariable scale. The sample size was 10 times the acceptable variable, with an additional 20% added to account for an expected loss of patients in follow-up for a final sample size of 168 patients. Conventional nursing measures were used in the control group, while the systematic nursing intervention Adopted Cancer Fatigue Scale (CFS), General Self-Efficacy Scale-Schwarzer (GSES), Self-Care Agency Scale (ESCA), and simple health scale (SF-36) were used in the observation group. The questionnaires were administered on admission and discharge.
    Results: At admission, there was no statistically significant difference in the scores on each scale between the groups. At discharge, the CFS and GSES scores in the observation group were 21.56 ± 2.24 and 51.16 ± 11.71, while those in the control group were 29.61 ± 3.48 and 41.58 ± 8.54, respectively, with statistically significant differences. The ESCA score in the observation and control groups was 112.09 ± 11.72 and 97.87 ± 9.26, respectively. Moreover, the scores in all dimensions (self-concept, self-responsibility, health knowledge level, and self-care skills) in the observation group were higher than those in the control group, with statistically significant differences. The SF-36 score in the observation and control groups was 75.51 ± 3.63 and 63.24 ± 3.41, respectively, with statistically significant differences. The scores in all dimensions (mental health, vitality, physical function, physical pain, social function, emotional function, and overall health level) in the observation group were higher than those in the control group, with statistically significant differences.
    Conclusion: Systemic nursing intervention for GC patients during the perioperative period could alleviate cancer-related fatigue, improve self-efficacy and self-nursing ability, and improve quality of life, which all have clinical value.
    Language English
    Publishing date 2022-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v10.i6.1843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Spinocerebellar Ataxia 36: From Mutations Toward Therapies.

    Lopez, Samuel / He, Fang

    Frontiers in genetics

    2022  Volume 13, Page(s) 837690

    Abstract: Spinocerebellar ataxia 36 (SCA36) is a type of repeat expansion-related neurodegenerative disorder identified a decade ago. Like other SCAs, the symptoms of SCA36 include the loss of coordination like gait ataxia and eye movement problems, but motor ... ...

    Abstract Spinocerebellar ataxia 36 (SCA36) is a type of repeat expansion-related neurodegenerative disorder identified a decade ago. Like other SCAs, the symptoms of SCA36 include the loss of coordination like gait ataxia and eye movement problems, but motor neuron-related symptoms like muscular atrophy are also present in those patients. The disease is caused by a GGCCTG hexanucleotide repeat expansion in the gene
    Language English
    Publishing date 2022-03-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.837690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Placenta percreta complicated with uterine rupture.

    Yang, Yilin / He, Fang

    Archives of gynecology and obstetrics

    2022  Volume 305, Issue 1, Page(s) 291–292

    MeSH term(s) Female ; Humans ; Placenta ; Placenta Accreta/surgery ; Pregnancy ; Pregnancy Trimester, Second ; Uterine Rupture/etiology ; Uterine Rupture/surgery
    Language English
    Publishing date 2022-01-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-021-06340-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The Effectiveness of Symptom Management Theory in Guiding Clinical Practice-A Systematic Review.

    Wei, Jianjian / Yan, Hongxia / Xiang, Yaqi / Ni, Jinnv / He, Fang

    Alternative therapies in health and medicine

    2024  

    Abstract: Objective: Symptom Management Theory has been extensively used in guiding clinical practice to reduce patients' symptom burden, improve their outcomes and quality of life. However, concerning various participants, settings and methods, the effectiveness ...

    Abstract Objective: Symptom Management Theory has been extensively used in guiding clinical practice to reduce patients' symptom burden, improve their outcomes and quality of life. However, concerning various participants, settings and methods, the effectiveness of practice and research based on the theory was inconsistent, which hindered the further implementation of this theory in clinical practice. Thus, this study aims to systematically evaluate the effectiveness of the Symptom Management Theory in guiding clinical practice.
    Methods: Systematic review. An online search of Chinese and English databases, including SinoMed, CNKI, WanFang Library, VIP database, MEDLINE, PubMed, Embase, Web of Science database, and Cochrane Library up to December 2023. This systematic review was conducted in accordance with the Joanna Briggs Institute critical appraisal checklist for randomized controlled trials and controlled clinical trials. The literature appraisal and extraction were independently conducted by two researchers. The third person was consulted if there was any disagreement between the two researchers.
    Results: A total of 20 articles (15 randomized controlled trials and five controlled clinical trials) were finally included. The overall quality of the articles was high. Additionally, the results showed that symptom management measurements based on the Symptom Management Theory could reduce the severity of patient's symptoms, alleviate their distress, relieve patients' anxiety and depression and improve their quality of sleep and quality of life.
    Conclusion: The Symptom Management Theory positively influenced clinical symptom management. It could provide theory-based symptom management methods in clinical practice to reduce patients' severity and burden of symptoms, level of anxiety, depression and distress. More high-quality original research should be conducted to further explore the theory's influence in guiding clinical practice in the future.
    Language English
    Publishing date 2024-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Application of Biomass Smoldering for Rural Building Heating in China: Strengths and Challenges.

    Wang, Xiaowei / Li, Xiuhua / Wang, Zhifang / Gao, Feng / He, Fang

    ACS omega

    2024  Volume 9, Issue 9, Page(s) 9991–9999

    Abstract: Biomass smoldering for rural building heating could be a potential choice for bioenergy utilization in China to reduce the pollution caused by agroresidues open burning and to satisfy the increased demand of rural building heating. Its strengths include ... ...

    Abstract Biomass smoldering for rural building heating could be a potential choice for bioenergy utilization in China to reduce the pollution caused by agroresidues open burning and to satisfy the increased demand of rural building heating. Its strengths include low pretreatment, transportation, and storage fees of fuel; ease of operation; good fertilizer characteristics of ash; use of latent heat of water vapor; pollution reduction; reduction of pests, weeds, and plant diseases on the farm; etc. However, controls of the burn rate and the gas emission are two challenges of the application, and related solutions of these challenges are discussed.
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c08804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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